Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
07/2003
07/24/2003CA2474002A1 Bispecific antibody dna constructs for intramuscular administration
07/24/2003CA2473570A1 Antisense compounds directed against human csf-1
07/24/2003CA2472203A1 The use of il6r/il6 chimera in nerve cell regeneration
07/24/2003CA2472170A1 Pharmaceutical compositions comprising polyanionic polymers and amphiphilic block copolymers and methods of use thereof to improve gene expression
07/24/2003CA2471891A1 Methods of inducing or enhancing connective tissue repair
07/24/2003CA2471480A1 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
07/24/2003CA2470359A1 Assay for the detection of factors that modulate the expression of ingap
07/24/2003CA2464131A1 Compositions and methods for controlled release
07/23/2003EP1329508A1 Novel g protein-coupled receptor protein and dna thereof
07/23/2003EP1329504A1 Nucleic acid of novel human kinesin-associated gene, protein encoded by the nucleic acid, peptide fragment thereof and anticancer agents comprising the nucleic acid and the like
07/23/2003EP1329499A2 Growth factor-responsive progenitor cells which can be proliferated in vitro
07/23/2003EP1328816A2 Regulation of neutral development by daedalos
07/23/2003EP1328807A2 Use of vanilloid 4 receptor and antagonists or agonists thereof for treating diseases associated with pain
07/23/2003EP1328662A2 Flea peritrophin nucleic acid molecules, proteins and uses thereof
07/23/2003EP1328653A2 Highly expressible genes
07/23/2003EP1328646A2 Regulation of human adenylate cyclase, type iv
07/23/2003EP1328641A2 Polynucleotides isolated from e. coli of nature b2/d+ a-, and uses thereof
07/23/2003EP1328637A2 Regulation of human secretin receptor-like gpcr
07/23/2003EP1328633A2 Human ion channel proteins and polynucleotides encoding the same
07/23/2003EP1328631A2 Her-2/neu fusion proteins
07/23/2003EP1328624A2 B7-like molecules and uses thereof
07/23/2003EP1328623A2 Human proteases and polynucleotides encoding the same
07/23/2003EP1328545A1 Human gene critical to fertility
07/23/2003EP1328537A1 Antisense modulation of bh3 interacting domain death agonist expression
07/23/2003EP1328536A1 Antisense modulation of glioma-associated oncogene-1 expression
07/23/2003EP1328298A1 Methods and compositions for modulating t cell activation and uses thereof
07/23/2003EP1328291A2 Viruses targeted to hypoxic cells and tissues
07/23/2003EP1328287A1 Compositions and methods for wt1 specific immunotherapy
07/23/2003EP1328254A2 Lipid formulations for target delivery
07/23/2003EP1328151A2 Isolated nucleic acids of the p-hyde family, p-hyde proteins, and methods of inducing susceptibility to induction of cell death in cancer
07/23/2003EP1067969B1 Polyene macrolide derivatives, use for vectoring molecules
07/23/2003EP1019078B1 Use of cartilage oligomeric matrix protein for the treatment of rheumatoid arthritis
07/23/2003EP0855919B1 Induction of mucosal immune responses by vitamin d3 and antigen-encoding dna complexe to cationic lipid
07/23/2003EP0743958B1 Avidin-biotin immunoconjugates
07/23/2003EP0670905B1 Recombinant viruses displaying a nonviral polypeptide on their external surface
07/23/2003CN1431907A Method of treating hepatitis delta viral infection
07/23/2003CN1431310A Transferring carrier of liver cancer target to ward gene introduced by acceptor of alphafetoprotein enhancement type epidermal growth factor dual controlled by transcription and transfer
07/23/2003CN1431304A Anti blood tumorous reverse VEGF gene sequence and expression carrier of recombination eukaryon
07/23/2003CN1115414C Virus carrier used for gene therapy
07/22/2003US6596851 Antibody for use in the treatment of cell proliferative disorders
07/22/2003US6596698 Localized arterial transduction of RB2/pl30 via a viral vector at the time of angioplasty drastically reduces neointimal hyperplasia and prevents restenosis
07/22/2003US6596544 Diagnosing atherosclerosis in mammals; obtain tissue sample, incbae with oxidized phospholipid, monitor adjustment in oxidation of phospholipid, absence of adjustment indicates atherosclerosis
07/22/2003US6596535 Adeno-associated viral vector for use as tool in the transfer of genetic information for use in the treatment of arthritis
07/22/2003US6596534 Utilization of osteocalcin promoter to deliver therapeutic genes to tumors
07/22/2003US6596533 Polypeptide for use in the treatment of infections and cell proliferative disorders
07/22/2003US6596526 Furin polypeptides with improved characteristics
07/22/2003US6596515 Insulin gene amplified from human genomic DNA by use of a pair of insulin primers and a K14 promoter gene amplified by use of a pair of K14 primers inserted together into pUChsneo
07/22/2003US6596488 Nucleotide sequences coding polypeptide for use in the diagnosis and treatment of cancer
07/22/2003US6596270 Administering the adenoviral gene transfer vector (exogenous) encoding a gene product to a muscle and the vector is neutralized outside of the muscle by systemic neutralizing antibodies; using a chimeric coat protein for cell entry
07/22/2003US6596269 Methods of treating chronic pain
07/22/2003US6596262 Modulated release particles for aerosol delivery
07/22/2003US6596206 Generation of pharmaceutical agent particles using focused acoustic energy
07/22/2003CA2109320C Peptide nucleic acids
07/18/2003CA2369985A1 Generation of recombinant adeno-associated viral vectors by a complete adenovirus-mediated approach
07/17/2003WO2003057926A1 Gene products differentially expressed in cancerous breast cells and their methods of use
07/17/2003WO2003057898A2 Methods and materials for modulating p2x2
07/17/2003WO2003057892A2 Viruses with enhanced lytic potency
07/17/2003WO2003057888A1 Cell-specific expression/replication vector
07/17/2003WO2003057878A1 INDUCTION OF THE FORMATION OF INSULIN-PRODUCING CELLS VIA GENE TRANSFER OF PANCREATIC β-CELL-ASSOCIATED TRANSCRIPTIONAL FACTOR
07/17/2003WO2003057870A1 Human phosphatidic acid phosphatase type 2-like protein
07/17/2003WO2003057869A1 Regulation of human sulfatase
07/17/2003WO2003057854A2 Novel proteins and nucleic acids encoding same
07/17/2003WO2003057849A2 Telomere-encoding synthetic dna nanocircles, and their use for the elongation of telomere repeats
07/17/2003WO2003057846A2 Methods and materials for modulating task-3
07/17/2003WO2003057843A2 Methods and materials for modulating trpc4
07/17/2003WO2003057840A2 Compositions for dna mediated gene silencing
07/17/2003WO2003057835A2 Pak5-related compositions and methods
07/17/2003WO2003057829A2 Methods of generating multispecific, multivalent agents from vh and vl domains
07/17/2003WO2003057827A2 Insulin-responsive dna binding protein-1 and methods to regulate insulin-responsive genes
07/17/2003WO2003057729A2 Mammal prolactin variants
07/17/2003WO2003057726A1 Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants
07/17/2003WO2003057252A1 Human mast cell-expressed membrane proteins
07/17/2003WO2003057190A1 Efficient nucleic acid encapsulation into medium sized liposomes
07/17/2003WO2003057164A2 Compounds for delivering substances into cells
07/17/2003WO2003057159A2 Psoriasin expression by breast epithelial cells
07/17/2003WO2003057148A2 Use of biomolecular targets in the treatment and visualization of tumors
07/17/2003WO2003057007A2 System for monitoring bacterial tumor treatment
07/17/2003WO2003056913A1 Nonhuman model animal lacking the ability to control lymphocyte migration
07/17/2003WO2003038057A3 Genetic vaccine against human immunodeficiency virus
07/17/2003WO2003030827A3 Compositions for and methods of treating and preventing sirs/sepsis
07/17/2003WO2003000896A3 POLYNUCLEOTIDES AND POLYPEPTIDES OF THE IFNα-5 GENE
07/17/2003WO2002099044A3 B3galts as modifiers of the p53 pathway and methods of use
07/17/2003WO2002083928A3 Nucleid acid and corresponding protein entitled 158p3d2 useful in treatment and detection of cancer
07/17/2003WO2002081646A3 Epitope sequences
07/17/2003WO2002058323A3 Method for identifying modulators of bace
07/17/2003WO2002055693A3 Method for inhibiting the expression of a target gene
07/17/2003WO2002040715A3 Molecules for disease detection and treatment
07/17/2003WO2002039947A3 Carrier vectors through an epithelium with tight junctions
07/17/2003WO2002017858A9 Role of fosb in bone formation
07/17/2003WO2002006479A3 Apoptosis-inducing dna sequences
07/17/2003US20030135873 Transgenic animal model coding fusion protein comprising nuclear protein and herpes viral vp16 protein; antidiabetic agents; uncoupling proteins
07/17/2003US20030134819 Recombinant bacterial cells for delivery of PNP to tumor cells
07/17/2003US20030134818 Lyophilizable and enhanced compacted nucleic acids
07/17/2003US20030134817 SIV derived lentiviral vector systems
07/17/2003US20030134815 Adenovirus mediated transfer of genes to the gastrointestinal tract. In particular, the present invention relates to a method of recombinant, replication-deficient adenovirus mediated transfer of therapuetic genes to the
07/17/2003US20030134812 Bladder and lower urinary tract syndromes, particularly, irrative symptoms, and to a method of treating same using alpha 1d-adrenergic receptor ( alpha 1dAR) antagonists. The invention further relates to a method of screening compounds
07/17/2003US20030134811 Methods and compositions comprising hydroxyapatite useful for the administration of therapeutic agents
07/17/2003US20030134810 Delivery of pharmacologically active agents associated with polymeric biocompatible materials. Compositions comprising a first, negatively charged pharmacologically active agent such as an oligonucleotide and a polycationic polymer such as
07/17/2003US20030134785 Secreted and transmembrane polypeptides and nucleic acids encoding the same
07/17/2003US20030134430 Novel amino acid sequences for human caenorhabditis elegans-like protein polypeptides