Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2003
08/07/2003WO2003064626A2 Double-stranded oligonucleotides
08/07/2003WO2003064625A2 Oligonucleotide compositions with enhanced efficiency
08/07/2003WO2003064607A2 Clinical grade vectors based on natural microflora for use in delivering therapeutic compositions
08/07/2003WO2003064473A2 Human monoclonal antibody fab fragments directed against hcv e2 glycoprotein and endowed with in vitro neutralizing activity
08/07/2003WO2003064471A2 Gene for peripheral arterial occlusive disease
08/07/2003WO2003064459A1 Peptides for increasing transfection efficiency
08/07/2003WO2003064441A2 Oligonucleotides comprising alternating segments and uses thereof
08/07/2003WO2003063911A1 Decoy-containing pharmaceutical compositions and method of using the same
08/07/2003WO2003063893A2 Fgfr agonists
08/07/2003WO2003063786A2 Methods and composition for delivering nucleic acids and/or proteins to the respiratory system
08/07/2003WO2003063785A2 Methods and composition for delivering nucleic acids and/or proteins to the intestinal mucosa
08/07/2003WO2003063773A2 Differentially-regulated prostate cancer genes
08/07/2003WO2003030826A3 Antisense modulation of insulin-like growth factor binding protein 5 expression
08/07/2003WO2003030616A3 21132, a human g-protein coupled receptor family member and uses therefor
08/07/2003WO2003018788B1 Improved nitroreductase enzymes
08/07/2003WO2003008640A3 Asthma-associated gene
08/07/2003WO2002092825B1 Retroviral vectors for gene therapy
08/07/2003WO2002064157A3 Localized myocardial injection method for treating ischemic myocardium
08/07/2003WO2002057457A3 Human proteins 55562 and 21617, and methods of use thereof
08/07/2003WO2002050288A9 Neocentromere-based mini-chromosomes or artificial chromosomes
08/07/2003WO2002033119A3 Mutations in the ferroportin 1 gene associated with hereditary haemochromatosis
08/07/2003WO2002013867A3 Augmented cognitive training
08/07/2003WO2002002593A3 Modulators of cellular proliferation and angiogenesis, methods for use and identification thereof
08/07/2003WO2001092578A3 Reagents and methods for identifying and modulating expression of genes regulated by retinoids
08/07/2003US20030150006 Gene transfer in poultry by introduction of embryo cells in ovo
08/07/2003US20030149998 Nucleotide sequences coding orphan receptors/membrane proteins OM-10 and UP-11 for detecting modulators of inflammation, nervous system activity and infection; antitumor/antiinflammatory agents; gene expression inhibition
08/07/2003US20030149256 Transferrin polynucleotides, polypeptides, and antibodies
08/07/2003US20030149242 Novel polypeptide
08/07/2003US20030149237 G-protein coupled receptor for treatment and prevention of eating, cancer, autoimmune, vision and nervous sytem disorders; antiinflammatory agents
08/07/2003US20030149235 Peptide complex comprising expression vector for transfer of heterologous polynucleotides to endothelial cells; gene therapy; drug delivery
08/07/2003US20030148990 Administering a therapeutically effective amount of an epidermal growth factor receptor (EGF-R) antagonist for therapy of hypersecretion of mucus in lungs
08/07/2003US20030148988 Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats
08/07/2003US20030148986 For therapy of atherosclerosis and other vascular diseases such as thrombosis, restenosis after angioplasty and/or stenting, and vein-graft disease after bypass surgery
08/07/2003US20030148985 Methods and reagents for the inhibition of hepatitis B virus replication
08/07/2003US20030148984 Molecular chemotherapy enhancement of radiotherapy
08/07/2003US20030148983 Polynucleotide therapy
08/07/2003US20030148981 Administering a therapeutic formulation containing the phosphorothioate oligonucleotide and at least one cyclodextrin to the mammal; monitoring the immune response of mammal
08/07/2003US20030148979 Traversal of nucleic acid molecules through a fluid space and expression in repair cells
08/07/2003US20030148978 Oligonucleotides antisense to mouse pituitary tumor transforming gene carboxy-terminal (PTTG-C) and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation
08/07/2003US20030148977 Delivering to mammalian cell that overexpresses pituitary tumor transforming gene carboxy-terminal (PTTG-C) formulation comprising polynucleotide to allow the polynucleotide to enter the cell, whereby expression of PTTG protein is prevented
08/07/2003US20030148976 For therapy of cancer, infectious disease, and allergic disorders
08/07/2003US20030148975 Method of achieving persistent transgene expression
08/07/2003US20030148972 Hereditary hemochromatosis gene
08/07/2003US20030148969 Antisense modulation of mucin 1, transmembrane expression
08/07/2003US20030148968 Delivering a transgene encoding an angiogenic protein or peptide to myocardium of patient by introducing a vector comprising transgene into coronary artery, wherein the transgene is is delivered to the myocardium and expressed
08/07/2003US20030148952 Recruiting endothelial precursor cells (bone marrow-derived angioblasts) to a wound site by administering angiopoietin-1; to enhance angiogenesis and the maintenance of organ transplants; wound healing agents; gene therapy
08/07/2003US20030148948 Super-active porcine growth hormone releasing hormone analog
08/07/2003US20030148947 MIP as a research tool for identification, characterization and purification of molecules involved in cellular transport and osmotic regulation; agonists/antagonists; vision defects; anitinflammatory agents; nervous system and kidney disorders
08/07/2003US20030148937 Methods and compositions for use in spliceosome mediated RNA trans-splicing
08/07/2003US20030148935 Novel nuclear factor polypeptides and nucleic acids encoding same
08/07/2003US20030148929 Polypeptide comprises diaminobutyric acid for safe delivery to cells
08/07/2003US20030148522 Equine infectious anemia viral plasmid for transfection of heterologous genes into mammalian cells
08/07/2003US20030148520 Replication-competent adenovirus vector comprising first and second genes co-transcribed as a single mRNA wherein the first and the second genes are under transcriptional control of a heterologous, target cell-specific transcriptional
08/07/2003US20030148516 Medium containing flt3 ligand for culturing hematophoietic cells
08/07/2003US20030148515 Generating blood producing tissues from central nervous system pluripotent cells for repair, regeneration or augmentation of mammalian hematopoietic system; gene therapy; tissue engineering; blood disorders; anticarcinogenic agents
08/07/2003US20030148514 Human embryonic germ cell line and methods of use
08/07/2003US20030148509 Retrovirus isolated from humans
08/07/2003US20030148507 RNA interference mediated inhibition of prostaglandin D2 receptor (PTGDR) and prostaglandin D2 synthetase (PTGDS) gene expression using short interfering RNA
08/07/2003US20030148465 Comprises membrane protein for diagnosis and treatment of atherosclerosis, viral and inflammatory diseases
08/07/2003US20030148456 Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins
08/07/2003US20030148451 Endothelial differntiation gene 6-like g protein coupled receptor
08/07/2003US20030148446 Acute neuronal induced calcium binding protein type 1 ligand
08/07/2003US20030148421 Comprises nucleotide sequences coding pancreatic polypeptides for use in treatment of diabetes and insulin resistance; drug screening
08/07/2003US20030148394 Methods and compositions for treating urological disorders using 1435, 559, 34021, 44099, 25278, 641, 260, 55089, 21407, 42032, 46656, 62553, 302, 323, 12303, 985, 13237, 13601, 18926, 318, 2058, or 6351 molecules
08/07/2003US20030148382 PanCAM nucleic acids and polypeptides
08/07/2003US20030148376 Secreted and transmembrane polypeptides and nucleic acids encoding the same
08/07/2003US20030148373 Comprises nucleotide sequences coding membrane protein/pro-polypeptide; antitumor agents; drug screening
08/07/2003US20030148327 Nucleic acid of given sequence; oligonucleotides and oligomers for detecting the cytosine methylation of genes; tumors and cancer
08/07/2003US20030148326 Diagnosis of diseases associated with dna transcription
08/07/2003US20030148325 Infectious clones
08/07/2003US20030148324 Polynucleotides which are of nature B2/D+ A- and which are isolated from E. coli, and biological uses of these polynucleotides and of their polypeptides
08/07/2003US20030148323 Analyzing nucleic acid and determining presence of mutant alleles encoding a protein with reduced activity/thermal stability; useful in diagnosing schizophrenia
08/07/2003US20030148312 Measuring the expression level of MAL gene; atopic dermatitis and bronchial asthma
08/07/2003US20030148305 Nucleic acids, polypeptides, single nucleotide polymorphisms and methods of use thereof
08/07/2003US20030148265 The factor allowing translocation is the homeodomain of antennapedia, and the viral protein can be from Flavivirus; fusion proteins as therapeutic agents
08/07/2003US20030148262 Chimeric alphavirus replicon particles
08/07/2003US20030147966 Nanoparticle delivery vehicle
08/07/2003US20030147924 Chlamydia antigens and corresponding dna fragments and uses thereof
08/07/2003US20030147912 Use generating immunity to human immunodeficiency virus-1 (HIV); also gene therapy for neurodegenerative disorders; AAV inverted terminal repeats flanking DNA sequences encoding an immunodeficiency virus protein and regulatory sequences
08/07/2003US20030147910 Vaccine compositions and methods useful in inducing immune protection against arthritogenic peptides involved in the pathogenesis of rheumatoid arthritis
08/07/2003US20030147907 Retroviral vectors
08/07/2003US20030147903 ABC transport polynucleotides, polypeptides and antibodies
08/07/2003US20030147895 Constructs for delivery of threrapeutic agents to neuronal cells
08/07/2003US20030147892 Antibodies against rat pituitary tumor transforming gene carboxy-terminal (PTTG-C) peptides
08/07/2003US20030147887 B-cell lymphoma specific antigen for use in diagnosis and treatment of B-cell malignancies
08/07/2003US20030147874 A targeted beta-lactamase enzyme can converting a prodrug to a drug product; used as antiproliferative disorder, anticarcinogenic agent treating cancer, treating autoimmune disease or infectious diseases
08/07/2003US20030147871 An immunotherapy by administering two engineered mammalian cells that each expresses IL-12 and IL-18 interleukins; synergistic response; antitumor treatment
08/07/2003US20030147868 A gene therapy, transfecting cells with exogenous genetic DNA for coding a desired therapeutic proteins, culturing the cells, for large-scale protein production
08/07/2003US20030147862 Administering a colony stimulating factor and/or a nucleic acids encoding the factor; treating a vascular tumor
08/07/2003US20030147855 Using a recombinant adeno-associated virus (rAAV) vector; useful for treating obesity and diabetes
08/07/2003US20030147854 Adenovirus vectors for gene therapy
08/07/2003US20030147853 Recombinant adeno-associated virus-mediated gene transfer via retroductal infusion of virions
08/07/2003US20030147846 Methods of using macrophage inflammatory protein-4 (MIP-4) and myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides
08/07/2003CA2475003A1 Double-stranded oligonucleotides
08/07/2003CA2474910A1 Oligonucleotide compositions with enhanced efficiency
08/07/2003CA2474777A1 Adenoviral vectors for modulating the cellular activities associated with pods
08/07/2003CA2474759A1 Gene for peripheral arterial occlusive disease
08/07/2003CA2474649A1 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
08/07/2003CA2474485A1 Light activated gene transduction using ultraviolet light for cell targeted gene delivery
08/07/2003CA2474414A1 Oligonucleotides comprising alternating segments and uses thereof
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