Patents
Sitemap › A61 - Medical or veterinary science; Hygiene › A61K - Preparations for medical, dental, or toilet purposes › A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2003
08/14/2003WO2001090421A3 Method of detecting inflammatory lung disorders
08/14/2003US20030153738 Homologs of bacterial AlkB gene (hABH); receptor binding assay; for repairing alkylated DNA, preventing/treating cell death/cancer
08/14/2003US20030153733 Antibiotic resistant drug screening; vaccines
08/14/2003US20030153527 Infecting animal cells with live invasive bacteria containing a eukaryotic expression cassette encoding gene, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA
08/14/2003US20030153526 Compositions contain antisense oligonucleotides that hybridize to Grb2 and Crkl nucleic acids, gene products of which are known to interact with tumorigenic protein bcr-abl
08/14/2003US20030153525 Identifies differential expression of 1465, 1587, 2146, 2207, 32838, 336 OR 52908 genes in tissues relating to pain sensation relative to their expression in normal or non-painful disease states
08/14/2003US20030153524 Including extracellular matrix production and/or deposition, neovascularization, inflammation, cell proliferation, cell migration, associated with connective tissue growth factor by administering agent that decreases expression of the factor
08/14/2003US20030153522 Rat pituitary tumor transforming gene (PTTG) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation
08/14/2003US20030153519 Drug delivering a nucleic acid and an RNase inhibitor to a target cell of a vascularized multi-cellular organism; RNA interference
08/14/2003US20030153518 Activation and inhibition of the immune system
08/14/2003US20030153498 An isolated polynucleotide encoding the polypeptide, treating infections, viral diseases, anorexia, bulimia, asthma, Parkinson's diseases, hypotension, hypertension, cancers, osteoporosis, angina pectoris, cardiovascular disorders
08/14/2003US20030153497 A polypeptides and polynucleotides encoding the polypeptides, for obesity, insulin resistance, type 2 diabetes, cachexia
08/14/2003US20030153490 Insulin conjugates and methods of use thereof
08/14/2003US20030153082 An isolated population of human hematopoietic cells that proliferates in culture, obtained by differentiating primate pluripotent stem (pPS) cells, and atleast 1% cells are CD45 + and population forms colonies
08/14/2003US20030153081 Viral core protein-cationic lipid-nucleic acid-delivery complexes
08/14/2003US20030153075 TGF-beta-specific covalently closed antisense molecule
08/14/2003US20030153063 Polypeptides; membrane proteins for diagonsis, prevention and treatment of cardiovascular disorders
08/14/2003US20030153054 Methods and compositions for use in spliceosome mediated RNA trans-splicing
08/14/2003US20030153040 Central nervous system disorders; antiinflammatory agents; antidiabetic agents; anticancer agents; hybrid polynucleotide
08/14/2003US20030152973 G-protein coupled receptor org3
08/14/2003US20030152970 Methods and compositions to treat pain and painful disorders using 577, 20739 or 57145
08/14/2003US20030152954 NPHS2 gene involved in the steroid-resistant nephrotic syndrome, protein encoded by said gene and diagnostic and therapeutic uses
08/14/2003US20030152947 Methods for detecting and treating the early onset of aging-related conditions
08/14/2003US20030152935 Comprises hybridization probes; electrophoresis; drug screening
08/14/2003US20030152914 From adeno-associated virus; for treatment of acute conditions requiring rapid gene expression
08/14/2003US20030152583 Dna which codes complex
08/14/2003US20030152582 CTL epitopes from EBV
08/14/2003US20030152579 Controlling biosynthesis of hybrid protein; therapy against Helicobacter infections
08/14/2003US20030152574 Modulate nucleic acid gene expression
08/14/2003US20030152573 Anticancer, antitumor agents
08/14/2003US20030152572 Blocking production of synoviocytes; antiinflammatory agents; prevent signal transduction
08/14/2003US20030152559 Infecting bone marrow cells; anticancer agents; inducing immunology response; viricides, antiallergens, autoimmune disease
08/14/2003US20030152558 Methods and compositions for the use of stromal cells to support embryonic and adult stem cells
08/14/2003US20030152553 Transfection, transduction of cells
08/14/2003CA2485064A1 Albumin-fused kunitz domain peptides
08/14/2003CA2483630A1 Compositions and methods for modulation of effects on phagocyte and lymphoid cell populations
08/14/2003CA2476275A1 Schwann cell bridge implants and phosphodiesterase inhibitors to stimulate cns nerve regeneration
08/14/2003CA2475539A1 Hiv inhibiting proteins
08/14/2003CA2475447A1 Short interfering rna molecules directed towards a tissue factor coding nucleic acid
08/14/2003CA2475382A1 Albumin-fused anti-angiogenesis peptides
08/14/2003CA2475273A1 Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy
08/14/2003CA2475101A1 Recombinant bovine immunodeficiency virus based gene transfer system
08/14/2003CA2474800A1 Polymorphisms in the human gene for tpmt and their use in diagnostic and therapeutic applications
08/14/2003CA2474783A1 Pluripotent embryonic-like stem cells derived from teeth and uses thereof
08/14/2003CA2474203A1 Compositions and methods for promoting lipid mobilization, glycogen mobilization, or both, in humans
08/14/2003CA2474011A1 Use of the mammalian cytokine, tslp/il-50, for modulating dendritic cell activity and treatment of immune disorders
08/14/2003CA2473853A1 Mammalian migration inducting gene and methods for detection and inhibition of migrating tumor cells
08/14/2003CA2473499A1 Minrs as modifiers of insulin receptor signaling and methods of use
08/14/2003CA2473212A1 Pharmaceutical composition which improves in vivo gene transfer
08/13/2003EP1335021A1 Genomes participating in rheumatoid arthritis, method of the diagnosis thereof, method of evaluating the onset possibility thereof, diagnostic kit for detecting them and therapeutic method and remedies for rheumatoid arthritis
08/13/2003EP1334358A1 Targeting cells having mad2 mutation for treatment and/or prevention of disease
08/13/2003EP1334195A2 Analogues, agonists, antagonists and variants of the oxidoreductase enzyme activity of the macrophage-migration inhibition factor (mif) as immunomodulators, medicaments, diagnostics and screening agents in inflammatory and immune diseases
08/13/2003EP1334194A2 Imaging, diagnosis and treatment of disease
08/13/2003EP1334191A2 Human g-protein coupled receptor and uses thereof
08/13/2003EP1334190A2 Human g-protein coupled receptor and uses thereof
08/13/2003EP1334187A2 C. elegans genes involved in viability and/or reproduction and uses thereof
08/13/2003EP1334186A2 Nucleic acid generating the abca7 gene, molecules modulating its activity and therapeutic applications
08/13/2003EP1334180A1 Isocitrate dehydrogenase, gene thereof, and use of the same in the treatment of obesity, hyperlipidemia, and fatty liver in lipid biosynthesis
08/13/2003EP1334179A2 A human serpin secreted from lymphoid cells lsi-01
08/13/2003EP1334174A2 Paramyxovirus vector for gene transfer to the cardiovascular system
08/13/2003EP1334126A1 Human stra6-like protein and nucleic acids encoding the same
08/13/2003EP1333863A2 Vector system for transducing th positive neurons
08/13/2003EP1333850A2 Method and composition for inhibition of tumor growth and enhancing an immune response
08/13/2003EP1333845A1 Treatment of t cell disorders
08/13/2003EP1333841A2 M. tuberculosis chaperonin 10 and uses thereof
08/13/2003EP1333840A2 M. tuberculosis chaperonin 60.1 and uses thereof
08/13/2003EP1333719A2 Corticotropin releasing factor receptor 2 deficient mice and uses thereof
08/13/2003EP1066060B1 Mesenchymal stem cells as immunosuppressants
08/13/2003EP0989859B1 Cns neuroregenerative compositions and methods of use
08/13/2003EP0614374B1 MURINE MONOCLONAL ANTIBODY (5c8) RECOGNIZES A HUMAN GLYCOPROTEIN ON THE SURFACE OF T-LYMPHOCYTES
08/13/2003CN1436239A Novel enzyme gene and its expression product
08/13/2003CN1436237A Nucleotide sequences involved in increasing or decreasing mammalian ovulation rate
08/13/2003CN1436236A Gasci基因 Gasci gene
08/13/2003CN1436233A Methods and compositions based on VEGF antisense oligonucleotides
08/13/2003CN1435427A Recombinant human alpha-prothymosin interleukin 2 gene and its expression and use
08/13/2003CN1117876C Screening assay for compounds stimulating somatostatin and insulin production
08/12/2003US6605712 Isolated DNA comprising a radiation inducible promoter linked to a region encoding a polypeptide; use for regulating polypeptide expression and inhibiting tumor growth; anticarcinogenic agent
08/12/2003US6605703 Deletion of the Hck binding region in the IL-6 receptor
08/12/2003US6605592 Protein HOFNF53
08/12/2003US6605464 Expressible polynucleotides encoding eukaryotic heat shock proteins
08/12/2003US6605449 Saturation mutagenesis to produce progenitor polynucleotide library
08/12/2003US6605443 Drug screening for compound which disrupts Smad7 transforming growth-beta factor superfamily signal transduction inhibitory activity
08/12/2003US6605437 Screening methods for compounds useful for the treatment of body weight disorders, including obesity
08/12/2003US6605426 Compounds, methods of screening, and in vitro and in vivo uses involving anti-apoptotic genes and anti-apoptotic gene products
08/12/2003US6605286 Delivery of biologically active polypeptides
08/12/2003US6605282 Inducing immune response against feline immunodeficiency virus; obtain animal, administer protective agent, detect immunological response against viral infection
08/12/2003US6605280 Interleukin-18 binding proteins, their preparation and use for blocking the activity of IL-18
08/12/2003US6605274 Method for in vivo regulation of cardiac muscle contractility
08/12/2003US6605271 Activating cell proliferation and differentiation in hematopoietic cells; obtain cells, incubate with modulator, monitor cell propagation
08/07/2003WO2003065046A2 Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor
08/07/2003WO2003065006A2 Methods and compositions for treating cancer
08/07/2003WO2003064680A2 Light activated gene transduction using ultraviolet light for cell targeted gene delivery
08/07/2003WO2003064666A1 Adenoviral vectors for modulating the cellular activities associated with pods
08/07/2003WO2003064665A2 Viral vector
08/07/2003WO2003064664A1 Physiologically regulated erythropoietin- exprressing vector for the treatment of anaemia
08/07/2003WO2003064663A1 Polymorphisms in elastin, fibrillin, and related genes as predisposing to restenosis and to atherosclerosis
08/07/2003WO2003064654A1 Human serine/threonine protein kinase
08/07/2003WO2003064647A1 Method of controlling circadian rhythm
08/07/2003WO2003064646A1 Novel peptide and use thereof
08/07/2003WO2003064629A2 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
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