Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
08/2004
08/12/2004WO2004066946A2 Method for evaluating the efficacy of certain cancer treatments
08/12/2004WO2004066933A2 Compositions and methods for treating cancer using igsf9 and liv-1
08/12/2004WO2004066908A2 Composition containing cationic lipids and a polynucleotide or a polypeptide and method for the targeted delivery of active substances
08/12/2004WO2004054969A3 Sacromastigophoric therapeutic agent delivery system
08/12/2004WO2004053061A8 Methods of therapy and diagnosis using targeting of cells that express lax
08/12/2004WO2004050859A3 Homologous recombination in multipotent adult progenitor cells
08/12/2004WO2004050680A3 Use of spliceosome mediated rna trans-splicing to confer cell selective replication to adenoviruses
08/12/2004WO2004048582A3 Recombinant poxvirus comprising at least two cowpox ati promoters
08/12/2004WO2004047734A3 Methods and immune modulatory nucleic acid compositions for preventing and treating disease
08/12/2004WO2004032880A3 Method for inhibiting angiogenesis with ship-1 inhibitors
08/12/2004WO2004032860A3 Hiv vaccine formulations
08/12/2004WO2004020592A3 Retroductal salivary gland genetic vaccination
08/12/2004WO2004009024A3 Modulation of protein kinase c-iota expression
08/12/2004WO2004007678A3 Codon optimized synthetic plasmids
08/12/2004WO2004007531A3 Activated checkpoint therapy and methods of use thereof
08/12/2004WO2003079977A3 Novel compositions and methods in cancer associated with altered expression of mcm3ap
08/12/2004WO2003037060A3 Compositions and methods for wt1 specific immunotherapy
08/12/2004WO2003032913A3 Methods and compositions for targeting proteins across the blood brain barrier
08/12/2004WO2003029293A3 Modulators of notch ic protease activity for use in immunotherapy
08/12/2004WO2002090504A3 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
08/12/2004US20040158045 Nucleotide sequences coding tumor necrosis factor binding proteins for prevention and treatment of bone disorders
08/12/2004US20040157792 antigen presenting cells (APCs) that express apoptosis inducing ligands and processed viral vector antigens are utilized to directly induce apoptosis of T-cells expressing the ligand receptor resulting in vector-specific T-cell tolerance
08/12/2004US20040157791 Systemic immune activation method using nucleic acid-lipid complexes
08/12/2004US20040157790 introducing the polynucleotide in a solution into a vessel of the heart, increasing the permeability of the vessel with hydrostatic pressure to the polynucleotide and delivering the polynucleotide to the cardiac tissue cell
08/12/2004US20040157775 Effector proteins of rapamycin
08/12/2004US20040157332 Using prokaryotic recombinase to initiate site specific insertion/deletion of extrachromosomal segments of DNA into eukaryotic genomes; gene therapy
08/12/2004US20040157329 Transfecting chondrocytes and other mesenchymal cells with vectors comprising genes capable of stimulating chondrogenesis, osteogenesis, growth, repair, regeneration and/or restoration of the cellular matrix
08/12/2004US20040157327 Pablo, a polypeptide that interacts with BCL-XL, and uses related thereto
08/12/2004US20040157308 Alpha-galactosidase as food-grade genetic marker
08/12/2004US20040157307 for treating a patient with cancer comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient; genetic engineering; drug delivery; kits
08/12/2004US20040157299 by transducing the tumor cells with a herpes simplex virus amplicon containing the gene for an immunomodulating protein; for multi-transduced cells for multi-targeted therapy; genetic engineering
08/12/2004US20040157296 Canine and feline B7-2 proteins, compositions and uses thereof
08/12/2004US20040157292 Sperm-specific cation channel, CatSper1, and uses therefor
08/12/2004US20040157282 Regulation of human dual specificity protein phosphatase 7-like protein
08/12/2004US20040157261 Kv10.1, a novel voltage-gated potassium channel from human brain
08/12/2004US20040157259 Novel human ion channel protein and polynucleotides encoding the same
08/12/2004US20040157258 Isolated nucleic acid comprising polynucleotide of given sequence; screening methods for identifying binding partners of polypeptides; use in diagnosis and treatment
08/12/2004US20040157250 Contacting a test compound with an expression system comprising an ABCA1 polynucleotide and detecting a change; use in treating coronary artery disease
08/12/2004US20040157246 Purified protein encoded by a nucleic acid hybridizable to a DNA of given sequence; use in diagnosis, prognosis and screening for a disposition to cardiovascular disorders
08/12/2004US20040157239 Endonuclease capable of cleaving DNA from divalent cations, which retains its activity in acidic to neutral pH range, and is not inhibited by G-actin; treatment of cystic fibrosis
08/12/2004US20040157232 for inhibiting apoptosis in mammalian cells; zinc finger domains; consensus sequences; genetic engineering; for treating AIDS, alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis (ALS), retinitis pigmentosa, autoimmune diseases
08/12/2004US20040157222 for drug screening anti-cancer, asthma, obesity, diabetes, central nervous system and cardiovascular disorder drugs; genetic engineering; kits
08/12/2004US20040156909 especially amphiphilic cationic or anionic vinyl ether polymers (e.g., copolymerized with maleic anhydride) electrostatically or covalently attached to the polynucleotide
08/12/2004US20040156904 matrix of PEG-g-chitosan and water insoluble polylactic acid, poly-lactide glycolide, polycaprolactones, EVA, or polyanhydridie used as a delivery vehicle for pharmaceuticals and biomedical materials.
08/12/2004US20040156848 Therapeutic uses of factors which inhibit or neutralize MIF activity
08/12/2004US20040156838 inducing cytotoxic T-lymphocytes that will specifically down-regulate B-cells producing autologous IgE, notably by means of nucleic acid vaccination or live vaccination; inducing a combined antibody and CTK response specific for IgE
08/12/2004US20040156833 Devices and methods for implanting transduced cells
08/12/2004US20040156830 Vector and pharmaceutical composition containing cell death inducing gene
08/12/2004US20040156828 Adeno-associated virus mediated B7.1 vaccination synergizes with angiostatin to eradicate disseminated liver metastatic cancers
08/12/2004US20040156827 Recombinant adenoviral vectors and their utility in the treatment of various types of fibrosis: hepatic, renal, pulmonary, as well as hypertrophic scars
08/12/2004US20040156826 Treatment of patients with multiple sclerosis based on gene expression changes in central nervous system tissues
08/12/2004US20040156825 Short immunomodulatory oligonucleotides
08/12/2004CA2514646A1 Factor viii polypeptide
08/12/2004CA2514517A1 Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
08/12/2004CA2514417A1 Custom-made meganuclease and use thereof
08/12/2004CA2514179A1 Modified trafficking patterns for arrestin and g-protein-coupled receptors via arrestin-ubiquitin chimera
08/12/2004CA2514062A1 Compositions and methods for treating cancer using igsf9 and liv-1
08/12/2004CA2513769A1 Method for evaluating the efficacy of certain cancer treatments
08/12/2004CA2513398A1 Antisense oligonucleotides that inhibit expression of hif-1
08/11/2004EP1445322A1 Packaging systems for human recombinant adenovirus to be used in gene therapy
08/11/2004EP1445315A1 Human and mammalian stem cell-derived neuronal survival polypeptides
08/11/2004EP1444999A1 Low pressure gas accelerated gene gun
08/11/2004EP1444986A1 Pharmaceutical preparation for the improved treatment of blood-clotting disorders
08/11/2004EP1444890A1 RS1 deficient transgenic animal and uses thereof
08/11/2004EP1444353A2 Herpes simplex virus amplicon vector targeting system and method of using same
08/11/2004EP1444347A2 METHOD FOR THE IN VITRO SYNTHESIS OF SHORT DOUBLE STRANDED RNAs
08/11/2004EP1444346A2 Sirna knockout assay method and constructs
08/11/2004EP1444335A2 Mutant purine nucleoside phosphorylase proteins and cellular delivery thereof
08/11/2004EP1444262A2 Growth hormone variations in humans and their uses
08/11/2004EP1444256A2 Enzyme-deficient c3 botulinum protein species and their use to promote neuronal growth and neuronal regeneration
08/11/2004EP1443971A2 METHOD OF USING 18080, A HUMAN SERINE CARBOXYPEPTIDASE FAMILY MEMBER
08/11/2004EP1443970A2 Promoters exhibiting endothelial cell specificity and methods of using same
08/11/2004EP1443955A1 Treatment of central nervous system disorders by use of pdgf or vegf
08/11/2004EP1443913A2 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
08/11/2004EP1443905A2 Compositions for oral gene therapy and methods of using same
08/11/2004EP1443818A2 Novel secreted proteins and their uses
08/11/2004EP1003776B1 Screening method using FREAC-11 transcription factor
08/11/2004EP0804453A4 Method for detection and treatment of breast cancer
08/11/2004EP0779922B1 Modified human c3 proteins
08/11/2004EP0749472B1 Extracorporeal cell culture and transplantation kits
08/11/2004EP0730648B1 HUMAN MUTATOR GENE hMSH2 AND HEREDITARY NON POLYPOSIS COLORECTAL CANCER
08/11/2004EP0604560B1 Human cyclin e
08/11/2004CN1520318A Intradermal delivery of vaccines and gene therapeutic agents via microcannula
08/11/2004CN1520304A Xenogenic oligo of or/and polyribonucleotides as agents for treatment of malignant twnours
08/11/2004CN1520303A Turnor therapy with alphavirus-based and high affinity laminin receptor-targeted vectors
08/11/2004CN1520259A Method to treat hemophilia by hepatic gene transfer of factor VIII/IX with vesicle vector
08/11/2004CN1519325A Shuttle plasmid of adenovirus and its constructing method
08/11/2004CN1519032A Plasmid for gene therapy of cardiac muscle
08/11/2004CN1161378C Antitumour polypeptide and gene therapy vector composition
08/11/2004CN1161110C Oral delayed immediate release formulation and method of preparation therefor
08/10/2004US6774227 Reating disorders related to cellular overproliferation comprising neutralizing the production or activity of macrophage migration inhibitory factor (mif)
08/10/2004US6774217 Use of fragile histidine triad gene (fhit) genes and their encoded proteins as diagnostic and therapeutic reagents for the detection and treatment of disease states associated with cell overproliferation
08/10/2004US6774216 Antibody for use in diagnosis and treatment of immunological, inflammatory and nervous system disorders
08/10/2004US6774120 Methods of inducing regulated pancreatic hormone production in non-pancreatic islet tissues
08/10/2004US6774119 Herpes simplex virus type 1 (hsv-1)-derived vector for selectively inhibiting malignant cells and methods for its use to treat cancers and to express desired traits in malignant and non-malignant mammalian cells
08/10/2004US6774118 Therapeutic use of CIS-element decoys in vivo
08/10/2004US6774105 Methods of using latent TGF-β binding proteins
08/10/2004US6773920 Delivery of functional protein sequences by translocating polypeptides
08/10/2004US6773909 Concentration and lysis of adenovirus-infected cells in a single unit operation
08/10/2004US6773881 By modulating vascular endothelial growth factor (vegf)