Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
07/2004
07/28/2004EP1440090A2 A synthetic chimeric fusion protein with immuno-therapeutic uses
07/28/2004EP1440083A2 Molecules
07/28/2004EP1440079A1 Acyclic linker-containing oligonucleotides and uses thereof
07/28/2004EP1439864A2 Methods for the treatment and diagnosis of tumorigenic and angiogenic disorders using 32616
07/28/2004EP1439863A2 Mnk kinase homologous proteins involved in the regulation of energy homeostasis and organelle metabolism
07/28/2004EP1439862A2 Methods and compositions for the treatment and diagnosis of pain disorders using 9805
07/28/2004EP1439861A2 Methods and kits for use in selecting approaches to treating cancer
07/28/2004EP1226244B1 Polypeptides with non-natural primary signalling motifs
07/28/2004EP1075461B1 Perfluorinated esters of alkanoyl l-carnitine for the preparation of cationic lipids for the intracellular delivery of pharmacologically active compounds
07/28/2004EP0719332B1 Monocyte macrophage line recombinant cells for gene therapy
07/28/2004CN1515672A Human chemotactic factor beta-8, chemotactic factor beta-1 and macrophage inflammatory protein-4
07/28/2004CN1515588A Biological function of human testis specific gene HSD-3,8 coded protein
07/28/2004CN1159455C Detection of DNA, RNA and proteins
07/28/2004CN1159453C Methods for identifying pathogenic markers in sample o normal cells
07/28/2004CN1159445C Recombinant adevovirus for tissue specifie expression in heart
07/28/2004CN1159440C Mutants of Rb and p53 genes and uses thereof
07/27/2004US6767997 Antibodies that bind deoxyribonuclease IIβ enzyme proteins
07/27/2004US6767743 Method and an apparatus for generating shockwave, a method and an apparatus for accelerating particles, an apparatus for delivering drugs, and a method and an apparatus for delivering DNA
07/27/2004US6767738 Repairing damaged or diseased, specialized or differentiated tissue in mature animals, like neuronal tissue such as retinas transplantation of adult, hippocampus-derived progenitor cells into a selected neural tissue site of a recipient
07/27/2004US6767736 Human ion channel protein and polynucleotides encoding the same
07/27/2004US6767720 Protein-protein or protein-dna interactions in a signal transduction or transcriptional pathway controlling cell growth/development in a wide range of cells; drug discovery, diagnosis and treatment of cancer and neurological disorders
07/27/2004US6767705 Recombinant expression construct encoding a reporter gene operably linked to a promoter from a gene the expression of which is induced by a retinoid, wherein the promoter does not contain a retinoic acid response elements site
07/27/2004US6767704 Methods of screening and diagnosing esophageal cancer by determining guanylin cyclase C expression
07/27/2004US6767699 Viral purification; mix viral preparation and ion exchange resins, remove unbound viral particles, elute bound viral particles, recover preferential replicon
07/27/2004US6767531 High dose radionuclide complexes for bone marrow suppression
07/24/2004CA2428744A1 Inhibition of lysozyme in treating sepsis-induced myocardial dysfunction
07/22/2004WO2004061456A2 Uses of hmgb, hmgn, hmga proteins
07/22/2004WO2004061423A2 Compositions and methods for diagnosing and treating colon cancers
07/22/2004WO2004061113A1 Adeno-associated virus mediated b7.1 vaccination synergizes with angiostatin to eradicate disseminated liver metastatic cancers
07/22/2004WO2004061110A1 Complementation method for producing rna-containing virus-like particles of hepatotropic viruses
07/22/2004WO2004061107A1 Cell growth inhibitor using sphingosine kinase 2, method of constructing fused protein having its nuclear localization signal, method of screening drug candidate, and screening kit
07/22/2004WO2004061106A1 Novel mammal-origin protein negatively regulating the expression of antigen presentation-associated molecule such as b7-2 molecule or mhc class ii molecule on cell surface and utilization of the same
07/22/2004WO2004061099A1 Method for treating an early embryo by creatin a chimera
07/22/2004WO2004060912A2 Chimeric capsid proteins and expression vectors for monocistronic expression of multiple genes
07/22/2004WO2004060476A2 Wound healing method and kits
07/22/2004WO2004060408A1 p53 TREATMENT OF PAPILLOMAVIRUS AND CARCINOGEN-TRANSFORMED CELLS IN HYPERPLASTIC LESIONS
07/22/2004WO2004060407A1 Calcium phosphate ceramics and particles for in vivo and in vitro transfection
07/22/2004WO2004060363A1 Method for producing sterile polynucleotide based medicaments
07/22/2004WO2004060323A2 Novel inhibitors of poxvirus replication
07/22/2004WO2004060303A2 Methods and reagents for the enhancement of virus transduction in the bladder epithelium
07/22/2004WO2004060302A2 Methods and compositions for the diagnosis, prognosis, and treatment of cancer
07/22/2004WO2004060295A2 Methods of inducing and maintaining immune tolerance
07/22/2004WO2004060280A2 Methods and compositions for inhibiting the growth of hematopoietic malignant cells
07/22/2004WO2004060274A2 Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
07/22/2004WO2004060269A2 Mda-7 and free radicals in the treatment of cancer
07/22/2004WO2004050844A3 Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases
07/22/2004WO2004045513A3 Coronary artery disease treatment
07/22/2004WO2004041843A3 Hop - a novel cardiac-restricted transcriptional factor potentially useful for cardiac regeneration and specification
07/22/2004WO2004035789A9 Gene families associated with cancers
07/22/2004WO2004029617A3 Diagnostics and therapeutics for diseases associated with human phosphodiesterase 11a (pde11a)
07/22/2004WO2004029229A3 Methods for promoting dopaminergic neuronal development by using ng4a-subfamily and wnt-ligands
07/22/2004WO2004028554A3 Skrp, astray, string, vacm associated with metabolic control
07/22/2004WO2004027049B1 Methods and compositions to generate and control the effector profile of t cells by simultaneous loading and activation of selected subsets of antigen presenting cells
07/22/2004WO2004027044A3 Triplex hairpin ribozyme
07/22/2004WO2004021977A3 Nucleic acid and corresponding protein entitled 98p4b6 useful in treatment and detection of cancer
07/22/2004WO2004015058A3 Nephritis treatment by gene therapy
07/22/2004WO2004013279A9 Helix-hairpin-helix motifs to manipulate properties of dna processing enzymes
07/22/2004WO2004005529A3 GEF-H1b: BIOMARKERS, COMPLEXES, ASSAYS AND THERAPEUTIC USES THEREOF
07/22/2004WO2003097158A3 Electroporation-mediated transfection of the salivary gland
07/22/2004WO2003077863A3 Method for overexpression of zwitterionic polysaccharides
07/22/2004WO2003075843A3 Multiple and multivalent dna vaccines in ovo
07/22/2004WO2003064680A3 Light activated gene transduction using ultraviolet light for cell targeted gene delivery
07/22/2004WO2002101076A3 Methods for targeted expression of therapeutic nucleic acid
07/22/2004WO2002099048A3 LIMKs AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
07/22/2004WO2002074239A3 Compositions and methods for the treatment and clinical remission of psoriasis
07/22/2004US20040143861 Using satellite artificial chromosome (SATAC) as gene therapeutic tool to transform and propagate transgenic cells and treat metabolic disorders
07/22/2004US20040143103 Comprises nucleotide sequences coding mitogens for treating psoriasis, vision defects, tumors and arthritis
07/22/2004US20040142900 polypeptide with the transport function of herpesviral VP22 protein and which can regulate cell cycle progression, e.g. proteins which can induce apoptosis, or proteins which can arrest cells from the cell cycle to arrest cell proliferation
07/22/2004US20040142899 Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals
07/22/2004US20040142897 Compositions and methods for inhibiting tumor growth and metastasis
07/22/2004US20040142893 Methods for treating and preventing vascular disease
07/22/2004US20040142892 expression cassettes comprising a eukaryotic promoter and a first RNA polymerase promoter operably linked to a nucleic acid encoding a secretable RNA polymerase comprising a RNA polymerase and a secretion domain, and internal ribosome entry site
07/22/2004US20040142886 use of vascular endothelial growth factor to enhance smooth muscle cell proliferation and to treat diseases associated with reduced smooth muscle cell proliferation
07/22/2004US20040142885 host cell; gene therapy
07/22/2004US20040142475 Delivery systems for bioactive agents
07/22/2004US20040142474 Liposomic structure comprising polyethylenimine (PEI), a fatty acid, cholesterol and polyethylene glycol for use as gene transfer tool in tissue engineering
07/22/2004US20040142473 Means and methods for fibroblast-like or macrophage-like cell transduction
07/22/2004US20040142472 Gene delivery vectors with cell type specificity for primary human chondrocytes
07/22/2004US20040142464 Transgenic human cells expressing superantigens/antiproliferative agents for use as gene therapeutic tools in cancer treatment ; tissue engineering
07/22/2004US20040142452 Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy
07/22/2004US20040142442 Human glycosylation enzymes
07/22/2004US20040142431 Nucleotide sequences comprising restriction fragment length polymorphisms coding polypeptide with antiproliferative, antiviral and antiparasitic effects
07/22/2004US20040142418 Novel neurotrophic factors
07/22/2004US20040142416 Treatment for phenylketonuria
07/22/2004US20040142395 Compositions and methods for identifying agents which modulate PTEN function and PI-3 kinase pathways
07/22/2004US20040142394 Method for diagnosing a tumor in a patient determining the concentration of PIBF
07/22/2004US20040142388 Method for detecting chronic dementia diseases, and corresponding VGF peptides and detection reagents
07/22/2004US20040142387 Mutants of GAD65 and Ian5 relating to diabetes
07/22/2004US20040142376 Deoxyribonuclease IIbeta proteins and cDNAs
07/22/2004US20040142363 N-acetylglycosaminyl transferase genes
07/22/2004US20040142348 solid phase synthesis; for diagnosis/treatment/prophyaxis; animal models; genetic engineering
07/22/2004US20040142317 Use of amino acid transporter atbo,+ as a delivery system for drugs and prodrugs
07/22/2004US20040142003 entirely vector-based intracellular system; introducing into a 293T cell expression vectors capable of expressing genomic or antigenomic vRNA segments, and a nucleoprotein, and an RNA-dependent polymerase
07/22/2004US20040142002 Recombinant poxvirus
07/22/2004US20040141997 Methods for treating or preventing infections from coagulase-negative staphylococci
07/22/2004US20040141994 Herpes simplex virus recombinase comprising an alkaline nuclease and a single stranded DNA binding polypeptide; has polynucleotide strand exchange activity; cloning kit
07/22/2004US20040141991 novel prostatic acid phosphatase and corresponding coding region derived from mouse; immunizing a subject with a xenogeneic polypeptide antigen, either alone, as part of a viral antigen construct, or as part of a pulsed dendritic cell preparation.
07/22/2004US20040141982 Use of genetically engineered antibodies to treat multiple myeloma
07/22/2004US20040141953 delivery of a neurotrophin to targeted defective, diseased or damaged cholinergic neurons
07/22/2004US20040141918 Nucleotide and deduced amino acid sequences of tumor gene Int6