Patents
Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
09/2004
09/30/2004WO2004083240A2 Regulation of gene expression
09/30/2004WO2004082720A1 Drug for treating hemophilia and method of treating hemophilia using the same
09/30/2004WO2004082703A1 Combined use of g-csf with angiogenetic factor
09/30/2004WO2004082574A2 Diagnostics and therapeutics for diseases associated with dopamine receptor d5 (drd5)
09/30/2004WO2004082573A2 Diagnostics and therapeutics for diseases associated with dopamine receptor d4 (drd4)
09/30/2004WO2004082567A2 Diagnostics and therapeutics for diseases associated with dopamine receptor d1a (drd1)
09/30/2004WO2004073603A3 Dna vaccine that expresses mutant adp-ribosyltransferase toxins which display reduced, or are devoid of, adp-ribosyltransferase activity
09/30/2004WO2004065578A3 Microparticles comprising polynucleotide adsorbed on the surface of or entrapped within the microparticles
09/30/2004WO2004064785A9 Cancer therapy sensitizer
09/30/2004WO2004063332A9 Cancer related genes
09/30/2004WO2004060408A8 p53 TREATMENT OF PAPILLOMAVIRUS AND CARCINOGEN-TRANSFORMED CELLS IN HYPERPLASTIC LESIONS
09/30/2004WO2004060295A3 Methods of inducing and maintaining immune tolerance
09/30/2004WO2004050126A3 Compositions for treating or preventing angiogenesis-dependent symptoms
09/30/2004WO2004038405A3 Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 43 (gpr43)
09/30/2004WO2004037164A3 Crosslinked compounds and methods of making and using thereof
09/30/2004WO2004029070A3 Methods for blocking adipocyte differentiation and triglyceride accumulation with dual-specificity tyrosine- (y) - phosphorylation regulated kinase 4 (dyrk4) inhibitors
09/30/2004WO2003103586A3 Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory cpg nucleic acids
09/30/2004WO2003082200A3 Potent oncolytic herpes simplex virus for cancer therapy
09/30/2004WO2003080105A9 Angiogenesis regulator genes, pharmaceutical preparations containing same and uses thereof
09/30/2004WO2003062447A3 Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression
09/30/2004WO2003049703A3 Chimeric infectious dna clones, chimeric porcine circoviruses and uses thereof
09/30/2004US20040194160 Expression vector comprising nucleotide sequences coding glucocorticoid-induced leucine-zipper family related protein (GILR) and tissue specific regulatory regions for transformation and generation of animal models to identify glucocorticoid hormones regulated genes associated with apoptosis control
09/30/2004US20040194159 Cloning pigs using donor nuclei from differentiated cells
09/30/2004US20040192630 nucleic acid constructs containing a HexB encoding element and a HexA encoding element; used in the treatment of Tay-Sachs and Sandoff disease; delivering a vector to a brain cell
09/30/2004US20040192629 Selectively inhibit the mutant while retaining wild-type gene expression to treat diseases caused by dominant mutants such as amyotrophic lateral sclerosis, Huntington's disease, Alzheimer's disease, and Parkinson's disease; administering to the cell an siRNA specific for the target allele
09/30/2004US20040192628 gene expression inhibition of the kinase to prevent neovascularization, treat cancer
09/30/2004US20040192627 Mitochondrial genome replenishment
09/30/2004US20040192625 administering an isolated nucleic acid molecule of the beta 2AR gene; gene therapy; beta 2-adrenergic receptors ( beta 2AR) gene
09/30/2004US20040192607 Transcriptional regulation of the human beta3-adrenergic receptor gene
09/30/2004US20040192593 Protease resistant ti-growth hormone releasing hormone
09/30/2004US20040192588 Pharmaceutical compositions comprising modified cns-derived peptides for promoting nerve regeneration and prevention of nerve degeneration
09/30/2004US20040191909 Glycerol viral suspension absent of divalent metal cations or alkali metal cations and capable for presevation and storage of adenovirus particles
09/30/2004US20040191905 Modulation of HIV replication by RNA interference
09/30/2004US20040191893 Implantable drug delivery system comprised of sealed thermoplastic polymer in association with permeable membrane; gene therapy; toxicity testing
09/30/2004US20040191866 Attenuated microorganisms for the treatment of infection
09/30/2004US20040191843 Cytotoxic mixture comprising polypeptides for treatment and prevention of cell proliferfative disorders
09/30/2004US20040191820 Using high throughput assay for detection and identification of modulators of telomeric complex binding activity; diagnosis and treatment of cell proliferative and age related disorders; antiproliferative agent
09/30/2004US20040191818 Compositions and methods for diagnosing and treating autoimmune diseases
09/30/2004US20040191800 Comprises nucleotide sequences coding protein which controls thermogenesis in human skeletal muscle and heart for prevention and treatment of obesity, cachexia, cardiovascular and muscular disorders
09/30/2004US20040191791 Comprises nucleotide sequences coding sodium voltage gated channels for identifying modulators for treatment of epilepsy; diagnosis of seizure disorders
09/30/2004US20040191773 Oligoribonucleotides and ribonucleases for cleaving RNA
09/30/2004US20040191767 Comprises nucleotide sequences coding hepatitis core protein fusion for generating vaccine to prevent infcetion and treat liver dysfunction; gene therapy and cell-mediated immune response
09/30/2004US20040191756 Transgenic rodent for diagnosing and identifying modulator for treatment and prevention inflammatory disorders
09/30/2004US20040191247 Use of il-18 inhibitors for treating or preventing cns injuries
09/30/2004US20040191230 Pharmaceutical composition for the diagnosis, prevention or treatment of a tumoral pathology comprising an agent modulating the polymerization state of actin
09/30/2004US20040191228 Methods of kidney transplantation utilizing developing nephric tissue
09/30/2004US20040191223 Combinatorial methods for inducing cancer cell death
09/30/2004US20040191222 Adenovirus serotype 34 vectors, nucleic acids and virus produced thereby
09/30/2004US20040191221 Delivering heterologous gene to a periosteal cell of a mammal; gene expression; bone disorders, osteoarthritis and osteoporosis; antiinflammatory agents
09/30/2004US20040191173 Metastasis models using green fluorescent protein (GFP) as a marker
09/30/2004CA2855229A1 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
09/30/2004CA2524255A1 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
09/30/2004CA2522786A1 Gene therapy vectors having reduced immunogenicity based on cd8 alpha-chain
09/30/2004CA2522380A1 Specific inhibition of allorejection
09/30/2004CA2519863A1 Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure
09/30/2004CA2519412A1 Combined use of g-csf and factors having angiogenic action
09/29/2004EP1462521A1 Human p53 splice variant displaying differential transcriptional activity
09/29/2004EP1462102A1 A method for promoting gonadal growth in an animal
09/29/2004EP1461450A1 T-bet compositions and methods of use thereof
09/29/2004EP1461449A2 System for monitoring bacterial tumor treatment
09/29/2004EP1461441A1 Flavivirus vaccine delivery system
09/29/2004EP1461436A1 Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers
09/29/2004EP1461427A2 Methods for targeted expression of therapeutic nucleic acid
09/29/2004EP1461358A1 Ifnar2 muteins, their production and use
09/29/2004EP1461087A1 Use of cd34+ hematopoietic progenitor cells for the treatment of cns disorders
09/29/2004EP1461073A2 Peptide agonists of prostate-specific antigen, and uses therefor
09/29/2004EP1461071A1 Muscle transcription factors
09/29/2004EP1461066A1 The use of il6r/il6 chimera in nerve cell regeneration
09/29/2004EP1461052A2 Nucleic acid injected into hepatic vein lumen and delivered to primate liver
09/29/2004EP1461014A2 Amphiphilic compounds and vesicles/liposomes for organ-specific drug targeting
09/29/2004EP1156812A4 Multiparticulate formulation
09/29/2004EP0956045B1 Assembly-deficient herpesvirus vaccine
09/29/2004EP0699079B1 Bioactive and/or targeted dendrimer conjugates comprising genetic materials
09/29/2004CN1533433A Method for virus propagation
09/29/2004CN1533284A Use of biologically active HIV-1 Tat, fragments or derivatives thereof for preventing or therapeutic vaccination and/or treating other diseases
09/29/2004CN1533283A Use of osteopontin for treatment and/or prevention of neurologic diseases
09/29/2004CN1533242A Foot and mouth disease virus vaccine
09/29/2004CN1532281A RFecombination of carcino-emhyyonic antigen gene fragment and gene vaccine
09/29/2004CN1531972A Method for treating tumor
09/29/2004CN1168736C Composition and method for delivery of nucleic acids
09/28/2004US6797703 Gene therapy using TGF-β
09/28/2004US6797702 Methods and compositions comprising DNA damaging agents and P53
09/28/2004US6797696 Contacting a bodily fluid with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (haah) polypeptide to form a complex and detecting the complex; treating malignant neoplasms by inhibiting haah.
09/28/2004US6797691 With pigment epithelium-derived factor (pedf)
09/28/2004US6797511 Basis of its ability to bind to presenilin 1; for treatment of alzheimer's disease
09/28/2004US6797502 Polypeptide for use in the treatment of hypertriglyceridemia, atherosclerosis and eating disorders
09/28/2004US6797494 Containing locus control regions (lcr) from epstein-barr virus; globulins; genetic engineering
09/28/2004US6797491 Human papilloma virus treatment
09/28/2004US6797281 Esters of I-carnitine or alkanoyl I-carnitines
09/28/2004US6797271 Methods for enhancing immune responses by fibroblast growth factor receptor 5 polypeptides
09/28/2004US6797269 Mesenchymal stem cells as immunosuppressants
09/28/2004US6797265 Therapy for metabolism disorders; gene therapy
09/28/2004CA2298414C Method for preventing and treating hearing loss using a neurturin protein product
09/24/2004WO2005111058A1 Intracellular delivery of osteoinductive proteins and peptides
09/23/2004WO2004081199A2 Novel compositions and methods for the treatment of immune related disease
09/23/2004WO2004081198A2 Methods for modulating angiogenesis with apelin compositions
09/23/2004WO2004081189A2 Multimodality imaging of reporter gene expression using a novel fusion vector in living cells and organisms
09/23/2004WO2004081188A2 Non-toxic membrane-translocating peptides
09/23/2004WO2004081167A2 Expression vectors comprising the mcmv ie2 promoter
09/23/2004WO2004081052A1 Soluble hybrid prion proteins and their use in the diagnosis, prevention and treatment of transmissible spongiform encephalopathies