Patents
Patents for C40B 60 - Apparatus specially adapted for use in combinatorial chemistry or with libraries (10,214)
05/1995
05/11/1995CA2175587A1 Synthesizing and screening molecular diversity
05/10/1995EP0651762A1 Method and apparatus for the rapid synthesis of substrate-bound or free peptides or oligonucleotides, flat material synthesized in this way and the use of such material
05/09/1995US5413762 Device for the purification of synthetic oligonucleotides
05/04/1995WO1995011995A1 Arrays of nucleic acid probes on biological chips
05/04/1995WO1995011755A1 Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
05/04/1995WO1995011748A1 Method and apparatus for creating biopolymer arrays on a solid support surface
05/03/1995EP0650393A1 Synthesis reaction column.
05/02/1995US5412087 Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
04/1995
04/27/1995WO1995011262A1 Apparatus and method for polymer synthesis using arrays
04/26/1995EP0649341A1 On-line process flow and reaction monitor.
04/19/1995EP0648221A1 Trityl monitor for automated polynucleotide synthesis
04/11/1995US5405783 Removing photoremovable protective group from region of substrate, contacting with protected amino acid, repeating to form peptide
04/11/1995US5405585 Designed for handling different type of fluids in flow system and reduces chemical reagent cross contamination; used for nuclic acid and other biosynthesis; automatic
04/04/1995US5403680 A microelectrode comprising an array of multiple micro-protrusions made of electroconductive polyaniline; improve charge storage capacity
03/1995
03/30/1995DE4329791A1 Method and device for automatic distribution of microfilter discs
03/29/1995EP0644792A1 System for solid phase reactions
03/07/1995US5396635 Power conservation apparatus having multiple power reduction levels dependent upon the activity of the computer system
03/07/1995US5395594 Simultaneous multiple chemical synthesizer
02/1995
02/22/1995EP0463036B1 Immobilized oligonucleotide probes and uses therefor
02/21/1995US5391463 Surface modification to create regions resistant to adsorption of biomolecules
02/21/1995US5391353 Metering device with radial arrangement of valves
02/16/1995WO1995004594A1 Method of dispensing micro-doses of aqueous solutions of substances onto a carrier and a device for carrying out said method
02/15/1995EP0638173A1 Optical and electrical methods and apparatus for molecule detection
02/14/1995US5389496 Processes and compositions for electroless metallization
02/08/1995EP0637344A1 Electrochemical treatment of surfaces
02/07/1995US5387395 Fluid distribution manifold
02/01/1995EP0636413A2 Nucleic acid amplification reaction apparatus and method
01/1995
01/31/1995US5386022 Primes and probes for the amplification and detection of aids associated nucleic acids
01/26/1995WO1995002566A1 Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses
01/26/1995CA2167391A1 Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses
01/24/1995US5384261 Channel blocking on rotating stage, treatment with light
01/19/1995WO1995002049A1 Purification method and apparatus
01/19/1995CA2166772A1 Purification method and apparatus
01/10/1995US5380495 Solid phase peptide synthesizer
01/05/1995WO1995000530A1 Hybridization and sequencing of nucleic acids
01/03/1995US5378916 Color imaging charge-coupled array with multiple photosensitive regions
01/03/1995US5378638 Solid state immunoassay, reagent dots applied by ink jet printing
12/1994
12/21/1994EP0624059A4 Combinatorial strategies for polymer synthesis.
12/08/1994WO1994028119A1 Novel process and apparatus
12/08/1994WO1994027719A1 Method and apparatus for conducting an array of chemical reactions on a support surface
11/1994
11/29/1994US5368823 Automated synthesis of oligonucleotides
11/17/1994EP0624059A1 Combinatorial strategies for polymer synthesis
11/15/1994US5364591 Device for moving a target-bearing solid through a liquid for detection while being contained
11/15/1994US5364068 Valve block assembly
11/09/1994EP0623626A1 Automated allyl deprotection in solid-phase synthesis
11/08/1994US5362447 Automated peptide synthesizer
11/02/1994EP0622115A1 Fluid delivery system
11/02/1994EP0622114A1 Laminated conduit plate for fluid delivery system
10/1994
10/18/1994US5356596 Apparatus for isolation of synthetic peptide without mechanical loss
10/12/1994EP0619321A1 Very large scale immobilized peptide synthesis
10/05/1994EP0574511B1 Method and device for heterogeneous phase synthesis of macromolecules such as peptides, polynucleotides or oligosaccharides
09/1994
09/13/1994US5346999 Method of nucleic acid extraction
09/07/1994EP0613400A1 Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices.
09/06/1994US5344613 Prevents splashing, agglomeration
09/01/1994WO1994019694A1 Thin film hpmp matrix systems and methods for constructing and displaying ligands
09/01/1994DE4406491A1 Cleavage apparatus
08/1994
08/31/1994EP0476014B1 Very large scale immobilized polymer synthesis
08/31/1994EP0373203B1 Method and apparatus for analysing polynucleotide sequences
08/30/1994US5342585 Apparatus for making multiple synthesis of peptides on solid support
08/18/1994WO1994018226A1 Automated synthesis of oligonucleotides
08/18/1994DE4403967A1 Process and apparatus for simultaneous multiple solid-phase synthesis
08/16/1994US5338831 Anchoring amino acid to inert porous material in compartments of carrier disk, dispensing measured quantity of reactant to each by rotating disk, while common synthesis steps proceed in all compartments at same time
08/16/1994US5338688 Method for the metered application of a biochemical analytical liquid to a target
08/03/1994EP0608779A1 Apparatus for peptide synthesis
08/02/1994US5333675 Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
07/1994
07/13/1994EP0605430A1 Kit for liquid phase quantitative analysis of oligonucleotides and method of use thereof
07/07/1994WO1994014972A1 Method and apparatus for enzymatic synthesis of oligonucleotides
07/07/1994CA2150670A1 Method and apparatus for enzymatic synthesis of oligonucleotides
07/06/1994EP0604552A1 Method of synthesizing diverse collections of oligomers.
07/05/1994US5325889 Laminated conduit plate for fluid delivery system
06/1994
06/28/1994US5324633 Exposing immobilized polymers to a fluorescently-labelled receptor in solutions of varying concentration
06/28/1994US5324591 Deep ultraviolet photolithographically defined ultra-thin films for selective cell adhesion and outgrowth and method of manufacturing the same and devices containing the same
06/28/1994US5324483 Apparatus for multiple simultaneous synthesis
06/14/1994US5320139 Fluid delivery system
06/07/1994US5318679 Photoprotected amines attached to support surface are selectively irradiated to deprotect preselected area so that support surface are subjected to chemical reaction to link aminoacids to the selectively deprotected area
05/1994
05/31/1994US5316954 Chemical reactors with multicompartment tubes and means for detaching, coupling and joining
05/31/1994US5316034 For dispensing reactive fluids
05/26/1994WO1994011388A1 Support for the synthesis of modular polymers
05/26/1994CA2148591A1 Support for the synthesis of modular polymers
05/18/1994EP0596915A1 Device for oligonucleotide assay and method of preparation thereof
05/11/1994WO1994010564A1 Process for separating substances from dilute solutions and suspensions
05/11/1994EP0558671A4 Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
05/11/1994EP0516672B1 Process and device for the simultaneous synthesis of several polypeptides
05/11/1994EP0344177B1 Porous wafer for segmented synthesis of biopolymers
05/11/1994DE4305651A1 Verfahren zur Trennung von Substanzen aus verdünnten Lösungen oder Suspensionen A process for the separation of substances from diluted solutions or suspensions
05/10/1994US5310674 Apertured cell carrier
04/1994
04/28/1994WO1994008759A1 Method and apparatus for robotically performing sanger dideoxynucleotide dna sequencing reactions
04/28/1994WO1994008711A1 Apparatus and method for multiple simultaneous synthesis
04/27/1994EP0593422A1 Method of synthesizing oligonucleotides adaptable to large scale syntheses.
04/20/1994EP0592968A1 Automated peptide synthesizer
03/1994
03/31/1994WO1994007142A1 Up-converting reporters for biological and other assays using laser excitation techniques
03/31/1994WO1994006291A1 Solid phase and combinatorial synthesis of compounds on a solid support
03/29/1994US5298259 Subunit delivery composition and method
03/17/1994WO1994005394A1 Specification method and apparatus for peptide synthesis and screening
03/16/1994EP0586600A1 Parallel sequential reactor.
03/15/1994US5294504 Three-dimensional microstructure as a substrate for a battery electrode
03/10/1994DE4230089A1 A laboratory robot for automated processing of proteins - uses a filtration aid, e.g. diatomite, after peptide pptn., and is useful for the parallel purificn. of several peptide(s)
02/1994
02/22/1994US5288644 High speed, automatic detection of mass weights of DNA fragments; mass spectrometry
02/22/1994US5288514 Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening
02/22/1994US5288468 Parallel sequential reactor
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