Patents
Patents for C40B 60 - Apparatus specially adapted for use in combinatorial chemistry or with libraries (10,214)
07/1996
07/23/1996US5538694 Device for simultaneously or sequentially carrying out chemical reactions
07/18/1996WO1996021859A1 Methods for production of large catalogued chemical libraries
07/18/1996CA2210071A1 Methods for production of large catalogued chemical libraries
07/16/1996US5536056 Gripping apparatus
07/10/1996EP0586600B1 Parallel sequential reactor
07/02/1996US5532128 Electric signal from probes that bond with associated target molecular structure
06/1996
06/26/1996EP0717749A1 Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
06/25/1996US5529756 Apparatus and method for polymer synthesis using arrays
06/20/1996WO1996018903A1 Combinatorial libraries having a predetermined frequency of each species of test compound
06/20/1996CA2207435A1 Combinatorial libraries having a predetermined frequency of each species of test compound
06/19/1996EP0717113A2 Computer-aided visualization and analysis system for nucleic acid sequence evaluation
06/18/1996US5527681 Immobilized molecular synthesis of systematically substituted compounds
06/13/1996WO1996017957A1 Methods and apparatus for dna sequencing and dna identification
06/13/1996CA2206815A1 Methods and apparatus for dna sequencing and dna identification
06/11/1996CA2095591C Device and method for moving a target-bearing solid through a liquid for detection while being contained
05/1996
05/23/1996WO1996015576A1 Liquid distribution system
05/23/1996WO1996015450A1 A partitioned microelectronic device array
05/23/1996CA2205066A1 A partitioned microelectronic device array
05/15/1996EP0653965B1 Fluid delivery system uitlizing multiple port valve
05/14/1996US5516664 Enzymatic synthesis of repeat regions of oligonucleotides
05/14/1996US5516491 Disposable reactor vessel
05/08/1996EP0593422B1 Method of synthesizing oligonucleotides adaptable to large scale syntheses
05/07/1996US5514569 Reducing inhibition of a nucleoside 5'-monophosphate on phosphodiesterase i by incubating the enzyme in the presence of a nucleoside 5'-monophosphate degrading enzyme
05/07/1996US5514501 Process for UV-photopatterning of thiolate monolayers self-assembled on gold, silver and other substrates
05/01/1996EP0708827A1 Purification method and apparatus
05/01/1996EP0708751A1 Synthesis of combinatorial arrays of organic compounds through the use of multiple component combinatorial array syntheses
04/1996
04/30/1996US5512131 Formation of microstamped patterns on surfaces and derivative articles
04/25/1996WO1996012186A1 Method and apparatus for efficient mimotope discovery
04/25/1996WO1996011878A1 The combinatorial synthesis of novel materials
04/25/1996CA2202286A1 The combinatorial synthesis of novel materials
04/24/1996EP0648221A4 Trityl monitor for automated polynucleotide synthesis.
04/23/1996US5510628 Using diamine as cell adhesion promoter
04/23/1996US5510270 Generating pattern of light and dark areas by selectively irradiating surface areas; deprotecting; contacting with receptor to identify oligonucleotide showing complementarity to receptor
04/16/1996US5508200 Placing small volumes of sample/regent combination at discrete locations in common test area on media and simulatneously measuring optical changes
04/10/1996EP0705271A1 Hybridization and sequencing of nucleic acids
04/09/1996US5506141 Apertured cell carrier
04/03/1996EP0703825A1 Method and apparatus for conducting an array of chemical reactions on a support surface
04/02/1996US5504190 Equimolar multiple oligomer mixtures, especially oligopeptide mixtures
04/02/1996US5503805 Apparatus and method for parallel coupling reactions
03/1996
03/19/1996US5500315 An article comprising an image pattern on a substrate
03/14/1996WO1996007917A1 Automated molecular biological diagnostic system
03/13/1996EP0700434A1 Novel process and apparatus
03/05/1996US5496473 Apparatus for processing biopolymer-containing columns
02/1996
02/22/1996WO1996005511A1 Biocatalytic methods for synthesizing and identifying biologically active compounds
02/22/1996WO1996005488A1 Automated system and method for simultaneously performing a plurality of signal-base assays
02/22/1996CA2197068A1 Automated system and method for simultaneously performing a plurality of signal-base assays
02/08/1996WO1996003212A1 Multidimensional conduit combinatorial library synthesis device
02/07/1996EP0695941A2 Method and apparatus for packaging a chip
02/06/1996US5489678 Photolabile nucleoside and peptide protecting groups
01/1996
01/25/1996WO1996001836A1 Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
01/11/1996DE4424307A1 Simultaneous, multiple solid phase synthesis of peptide(s), other bio-organic polymers, or libraries of them
01/04/1996DE4422049A1 Ultra-micro-electrodes and nano-sized array for chemical and biochemical analysis
12/1995
12/28/1995WO1995035505A1 Method and apparatus for fabricating microarrays of biological samples
12/21/1995WO1995034575A1 Combinatorial peptide library and method
12/20/1995EP0495066B1 Apparatus for carrying out biochemical reactions
12/14/1995WO1995033846A1 Bioarray chip reaction apparatus and its manufacture
12/12/1995US5474796 Immobilization
12/05/1995US5472672 Apparatus and method for polymer synthesis using arrays
11/1995
11/29/1995EP0683790A1 Automated synthesis of oligonucleotides
11/16/1995WO1995030773A1 Method of nucleic acid transfer
11/14/1995US5466608 Process and apparatus for heterogeneous phase synthesis of macromolecules such as peptides, polynucloetides or oligosaccharides
11/02/1995EP0562047A4 Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
10/1995
10/31/1995US5462748 For stepwise addition of biopolymer subunits to growing biopolymer chain on a solid phase support
10/24/1995US5460786 Cleaving peptied-solid support bond and removing side chain protecting groups
10/18/1995EP0629144B1 Device for simultaneously or successively carrying out chemical reactions
10/11/1995EP0675966A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
10/11/1995EP0675963A1 Method and apparatus for enzymatic synthesis of oligonucleotides
10/11/1995EP0675760A1 Method and apparatus for creating biopolymer arrays on a solid support surface
10/03/1995US5455008 Apparatus for robotically performing sanger dideoxynucleotide DNA sequencing reactions using controlled pipet
09/1995
09/28/1995WO1995026061A1 Optical sources having a strongly scattering gain medium providing laser-like action
09/27/1995EP0593460B1 Method and apparatus for biopolymer synthesis
09/26/1995US5453487 Solid phase peptide synthesizer
09/26/1995US5453247 Instrument and method for the sequencing of genome
09/21/1995WO1995025116A1 Method and apparatus for performing multiple sequential reactions on a matrix
09/21/1995CA2184589A1 Method and apparatus for performing multiple sequential reactions on a matrix
09/20/1995EP0672751A1 Gene macromolecule reaction method and apparatus therefor
09/20/1995EP0672049A1 Support for the synthesis of modular polymers
09/12/1995US5449754 Generation of combinatorial libraries
09/05/1995US5448582 Optical sources having a strongly scattering gain medium providing laser-like action
09/05/1995US5447692 Automatic chemical reactors and reservoirs for controlling delivery and bubbling
08/1995
08/31/1995WO1995018814A3 Polymer-supported solution synthesis of oligosaccharides
08/29/1995US5445934 Selective photoremovable groups on surface
08/17/1995WO1995022056A1 Highly specific surfaces for biological reactions, method of preparation and utilization
08/17/1995WO1995021939A1 Method for ordering macromolecules by means of a moving meniscus, and uses thereof
08/10/1995WO1995021265A1 Methods for discovering ligands
08/08/1995US5439650 Reaction vessel
08/01/1995US5437979 Immobilizing on support located inside the tip of a pipette; automated; programmable; time reduction; uniformity
07/1995
07/26/1995EP0663856A1 Apparatus and method for multiple simultaneous synthesis
07/25/1995US5436493 Color imaging charge-coupled array with multiple photosensitive regions
07/25/1995US5436143 Genetic engineering; one vessel; enzyme deactivation
07/13/1995WO1995018814A2 Polymer-supported solution synthesis of oligosaccharides
07/13/1995CA2180979A1 Polymer-supported solution synthesis of oligosaccharides
07/05/1995EP0660936A1 Up-converting reporters for biological and other assays using laser excitation techniques
07/04/1995US5429807 Method and apparatus for creating biopolymer arrays on a solid support surface
06/1995
06/21/1995EP0658566A1 Process of polynucleotide preparation on a solid support and apparatus allowing it to be carried out
06/13/1995US5424186 Very large scale immobilized polymer synthesis
05/1995
05/30/1995US5419874 Synthesis reaction column
05/24/1995EP0653965A1 Fluid delivery system uitlizing multiple port valve.
05/11/1995WO1995012808A1 Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
05/11/1995WO1995012608A1 Synthesizing and screening molecular diversity