Patents
Patents for C40B 60 - Apparatus specially adapted for use in combinatorial chemistry or with libraries (10,214)
02/1994
02/22/1994US5288464 Peptide synthesis
02/15/1994US5286789 Solid phase multiple peptide synthesis
02/03/1994WO1993022678A3 Optical and electrical methods and apparatus for molecule detection
01/1994
01/20/1994WO1994001215A1 Fluid delivery system utilizing multiple port valve
01/20/1994WO1994001214A1 On-line process flow and reaction monitor
01/20/1994WO1994001213A1 Synthesis reaction column
01/06/1994WO1994000471A1 Trityl monitor for automated polynucleotide synthesis
12/1993
12/28/1993US5273718 Applying gas pressure to the wells of a microtiter plate; and an inflatable collar for sealing
12/28/1993US5273715 Automated system for providing a sequence of chemicals to a reaction process
12/28/1993US5273656 System for solid phase reactions
12/21/1993US5272081 System and methods for cell selection
12/21/1993US5272075 System for solid phase reactions
12/14/1993US5270183 Polymerase chain reaction to amplify DNA
12/09/1993WO1993024625A1 Gene macromolecule reaction method and apparatus therefor
12/08/1993EP0573098A2 Device and method for providing confined reaction and detection
11/1993
11/16/1993US5262530 Solid phase synthesis on polystyrene support, phosphoramidite chemistry
11/11/1993WO1993022680A1 Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
11/11/1993WO1993022678A2 Optical and electrical methods and apparatus for molecule detection
11/11/1993WO1993022480A1 Electrochemical treatment of surfaces
10/1993
10/27/1993EP0431059B1 A method for carrying out organic chemical reactions and apparatus for carrying out that method
10/14/1993WO1993020130A1 Apparatus for processing biopolymer-containing columns
10/14/1993WO1993020096A1 Oligonucleotide libraries useful for producing primers
10/12/1993US5252296 Method and apparatus for biopolymer synthesis
10/05/1993CA1322745C Porous wafer for segmented synthesis of biopolymers
09/1993
09/30/1993DE4310169A1 Automatic chemical analyser for blood or fluid samples - has bar-coded micro-plates containing reaction cells for photoelectric evaluation with sample identification and result validation
09/29/1993EP0562047A1 Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
09/29/1993EP0562025A1 Very large scale immobilized polymer synthesis
09/16/1993WO1993017785A1 Device for simultaneously or successively carrying out chemical reactions
09/16/1993DE4206488A1 Vorrichtung zur durchfuehrung zeitgleich oder sequentiell ablaufender chemischer reaktionen Apparatus for carrying out simultaneously or sequentially occurring chemical reactions
09/08/1993EP0558671A1 Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures
09/07/1993US5243540 Computer-driven amino acid indexer for peptide synthesis
09/07/1993US5242974 Polymer reversal on solid surfaces
09/02/1993WO1993017126A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
09/02/1993CA2130562A1 Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
09/01/1993EP0558050A1 Apparatus and method for isolation of synthetic peptide without loss of reagents
08/1993
08/31/1993US5240680 Automated apparatus for use in peptide synthesis
08/18/1993EP0555706A1 Agitation stabilizer in solidphase peptide synthesizer
08/02/1993EP0604552A4 Method of synthesizing diverse collections of oligomers.
07/1993
07/27/1993US5231029 Spraying, incubation
06/1993
06/24/1993WO1993012427A1 Automated apparatus for use in peptide synthesis
06/16/1993EP0546393A1 Peptide synthesizer
06/02/1993EP0239600B1 Apparatus for, and methods of, operating upon a fluid
05/1993
05/27/1993WO1993010161A1 Polymer reversal on solid surfaces
05/27/1993WO1993009872A1 Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
05/27/1993WO1993009668A1 Combinatorial strategies for polymer synthesis
05/27/1993CA2123801A1 Test device comprising a plate containing a multiplicity of wells with an associated metering device, as well as a kit which comprises these devices and use of the devices
05/26/1993EP0543550A1 Method and apparatus for molecule detection
05/12/1993EP0541340A2 Biopolymer synthesis apparatus and method
04/1993
04/20/1993US5204455 Oligonucleotides having internal phosphonate linkages from a fast and efficient solid phase synthesis
04/20/1993US5203368 Matrix of valves
04/13/1993US5202418 Method of performing multiple synthesis of peptides on solid carrier
04/01/1993WO1993006121A1 Method of synthesizing diverse collections of oligomers
04/01/1993CA2118806A1 Method of synthesizing diverse collections of oligomers
03/1993
03/18/1993WO1993004756A1 System for solid phase reactions
03/18/1993CA2116360A1 System for solid phase reactions
03/03/1993EP0529573A1 Solid-phase synthesizer
03/03/1993EP0529504A2 Apparatus for the simultaneous synthesy of different peptides
02/1993
02/23/1993US5188733 Apparatus and process for effecting sequential peptide syntheses
02/23/1993US5188148 Conduit plate for fluid delivery system
02/18/1993WO1993003182A1 Kit for liquid phase quantitative analysis of oligonucleotides and method of use thereof
02/18/1993WO1993003181A1 Device for oligonucleotide assay and method of preparation thereof
02/18/1993WO1993002992A1 Synthesis of chain chemical compounds
02/18/1993CA2114628A1 Device for oligonucleotide assay and method of preparation thereof
02/18/1993CA2114627A1 Kit for liquid phase quantitative analysis of oligonucleotides and method of use thereof
02/16/1993US5187034 Sulfonic acid dopant
02/16/1993US5186898 Single coupling
02/16/1993US5186824 Rotating processor; sequential separation by fluid density
02/10/1993EP0526691A2 Apparatus for carrying out chemical processes on a sample of chemical material
01/1993
01/26/1993US5182366 Simplified method of forming identifiable sequences of amino acids
01/07/1993WO1993000625A1 Computer-controlled, module type, multipurpose synthesizer
01/05/1993US5176995 Detection of viruses by amplification and hybridization
12/1992
12/29/1992US5175209 Porous wafer for segmented synthesis of biopolymers
12/08/1992CA1311332C Bop reagent for solid phase peptide synthesis
11/1992
11/26/1992WO1992021079A1 Parallel sequential reactor
11/26/1992WO1992020778A1 Biochemical reaction control
11/26/1992CA2109828A1 Parallel sequential reactor
11/17/1992US5164491 High efficiency
11/03/1992US5160378 Rods attached to plate in rows are cleaned by reagent solution; peptide synthesis, immunoassay
10/1992
10/21/1992EP0509612A2 Process for amplifying and detecting nucleic acid sequences
10/20/1992US5156809 Apparatus for the stepwise performance of chemical reactions
10/07/1992EP0506993A1 High resolution patterning on solid substrates
10/06/1992US5153319 Process for preparing polynucleotides
10/06/1992CA1308467C Apparatus and process for reagent fluid dispensing and printing
09/1992
09/23/1992EP0505012A2 Means for amplifying nucleic acid sequences
09/22/1992US5149798 Process for synthesizing oligonucleotides and their analogs adaptable to large scale syntheses
09/17/1992WO1992015867A1 Method and device for heterogeneous phase synthesis of macromolecules such as peptides, polynucleotides or oligosaccharides
09/17/1992CA2105470A1 Process and apparatus for the heterogenous phase synthesis of macromolecules such as peptides, polynucleotides or oligosaccharides
09/16/1992EP0503683A1 A process for the manufacture of peptides by solid phase synthesis
09/15/1992US5147608 Apparatus and process for performing repetitive chemical processing
09/09/1992EP0502589A2 Kit for use in amplifying and detecting nucleic acid sequences
09/09/1992EP0502588A2 Process for amplifying nucleic acid sequences
09/01/1992US5143854 Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
08/1992
08/20/1992WO1992013967A1 Device and method for the automated cycling of solutions between two or more temperatures
08/19/1992EP0499127A1 Conduit plate for fluid delivery system
08/11/1992US5137698 Apparatus for carrying out chemical reaction sequences
08/11/1992US5137695 Polypeptides
08/04/1992US5135720 Reaction chamber for amino-terminal sequence analysis of proteins or peptides
07/1992
07/22/1992EP0495066A1 Apparatus for carrying out biochemical reactions.
07/21/1992US5132418 On modified silica support
07/14/1992CA1304916C Apparatus for the parallel performance of a plurality of chemical reaction sequences
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