Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
08/1988
08/24/1988CN87106856A Prodn. of glyceraldehyde-3 phosphate dehydrogenase
08/24/1988CN87105411A Prepn. method about t cell and b cell antigens of hepatitis b virus surface antigen
08/23/1988US4766203 Insecticides
08/23/1988US4766077 Ice nucleation deficient microorganisms by genetic manipulation
08/23/1988US4766075 From cell cultures using recombitant dna
08/23/1988US4766073 Expression of biologically active PDGF analogs in eucaryotic cells
08/23/1988US4766072 Vectors for in vitro production of RNA copies of either strand of a cloned DNA sequence
08/23/1988US4766069 Recombinant DNA which codes for interleukin-1 B
08/23/1988US4766068 Cytochrome P-450MC gene, expression plasmid carrying the said gene, yeasts transformed with the said plasmid and a process for producing cytochrome P-450MC by culturing the said transformant yeasts
08/23/1988US4766067 Genetic engineering
08/23/1988US4766066 Genetic engineering
08/23/1988US4766062 Displacement polynucleotide assay method and polynucleotide complex reagent therefor
08/23/1988EP0215942A4 Polynucleotide assay reagent and method.
08/23/1988CA1240941A1 Method of inserting amino acid analogs into proteins
08/23/1988CA1240940A1 A-factor and its processing signals
08/23/1988CA1240938A1 Hybrid cell lines producing monoclonal antibodies directed against treponema
08/17/1988EP0278941A1 Expression of the P. falciparum circumsporozoite protein by yeast
08/17/1988EP0278940A2 Hepatitis B virus surface antigens and hybrid antigens containing them
08/17/1988EP0278776A2 Methods and deoxyribonucleic acid for the preparation of tissue factor protein
08/17/1988EP0278706A2 Recombinant plasmid for the expression of L-phenylalanine ammonia-lyase and transformed strain carrying same
08/17/1988EP0278697A2 A system for release of proteins from microbe cells
08/17/1988EP0278696A2 An arg-serpin human plasminogen activator inhibitor designated PAI-2
08/17/1988EP0278667A2 Hybrid RNA virus
08/17/1988EP0278659A2 OCS enhancer
08/17/1988EP0278658A2 Use of a plant anaerobic regulatory element
08/17/1988EP0278541A1 Antigenically active proteins and peptides, and transmissible gastro-enteritis virus TGEV vaccines
08/17/1988EP0278513A2 Process of preparing single-stranded DNA
08/17/1988EP0278487A2 Process for the inactivation of enveloped viri in protein preparations produced in vitro by means of a single cell
08/17/1988EP0278355A2 Novel expression system
08/17/1988EP0278220A1 Diagnostic assays using nucleic acid probes
08/17/1988EP0278160A2 Human monoclonal anti cancer antibodies, hybridoma cell lines producing them and their uses
08/17/1988EP0278121A1 Microbially produced bovine growth hormone (BGH) and its use
08/17/1988EP0278112A2 Pancreatic secretory trypsin inhibitor and its variants produced by genetic engineering
08/17/1988EP0278005A1 Dna for shuttle vector
08/17/1988EP0277954A1 Promoter system
08/17/1988CN87108308A Polypeptides and production thereof
08/17/1988CN87107275A Monoclonal antibody specific to neutrophils
08/16/1988US4764593 Manufacture and expression of genes for urogastrone and polypeptide analogs thereof
08/16/1988US4764510 Antibiotic A42125 and process for its production
08/16/1988US4764504 Novel atrial natriuretic/vasodilator polypeptides
08/16/1988US4764473 Chamber for the treatment of cells in an electrical field
08/16/1988US4764460 Hybridization probe assays, nonstructural
08/16/1988US4764370 Vaccine utilizing an avirulent strain of Salmonella typhimurium
08/16/1988CA1240629A1 Deoxyribonucleic acid molecules useful as probes for detecting deleterious genes incorporated into chromosomal dna
08/11/1988WO1988005826A1 Polypeptides with activity against gram-positive and gram-negative bacteria
08/11/1988WO1988005825A1 A method for producing factor viii in high yield
08/11/1988WO1988005822A1 Des-epidermal growth factor plasminogen activators
08/11/1988WO1988005821A1 Periplasmic protease mutants of escherichia coli
08/11/1988WO1988005820A1 Recombinant alveolar surfactant protein
08/11/1988WO1988005819A1 RECOMBINANT PLASMID DNA pPR-IFNbeta1-13, CODING FOR SYNTHESIS OF HUMAN FIBROBLAST beta1-INTERFERON, METHOD OF ITS CONSTRUCTION AND STRAIN OF BACTERIA ESCHERICHIA COLI VNIIGENETIKA VL 903 (pPR-IFNbeta1-13) AS PRODUCER OF HUMAN beta1-INTERFERON, CONTAINING IT
08/11/1988WO1988005818A1 RECOMBINANT PLASMID DNA pPR-IL2-19, CODING FOR SYNTHESIS OF HUMAN INTERLEUKIN-2, METHOD OF ITS CONSTRUCTION AND STRAIN OF BACTERIA ESCHERICHIA COLI VNIIGENETIKA VL 903 (pPR-IL2-19) AS PRODUCER OF HUMAN INTERLEUKIN-2, CONTAINING IT
08/11/1988WO1988005817A1 Expression of the p. falciparum circumsporozoite protein by yeast
08/11/1988WO1988005816A1 Polypeptide
08/11/1988WO1988005786A1 Colony stimulating factors having reduced levels of carbohydrate
08/11/1988WO1988005785A1 Molecules comprising at least one peptidic sequence carrying one or a plurality of epitopes characterizing a protein produced by p. falciparum in hepatocytes and compositions containing them
08/11/1988WO1988005659A1 Human proteins having anticoagulant and anti-inflammatory activity
08/11/1988WO1988005466A3 Tandem gene eukaryotic expression vectors
08/11/1988WO1988003807A3 Production and use of a novel t-cell suppressor factor
08/10/1988EP0277773A1 Hybrid cytomegalovirus (CMV) and vaccine
08/10/1988EP0277770A1 Alpha-mating factor promoter is modified by deleting pre-pro secretory leader sequence
08/10/1988EP0277751A2 Modified fibrinolytic enzyme
08/10/1988EP0277674A1 A process for producing compounds containing a terminal hydroxyl or epoxy group; and microorganisms suitable therefor
08/10/1988EP0277563A1 Polypeptide and production thereof
08/10/1988EP0277313A1 Hybrid plasminogen activators
08/10/1988EP0277212A1 Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators, and gene coding for the inhibitor.
08/10/1988EP0277195A1 Transcriptional control element adapted for regulation of gene expression in animal cells
08/10/1988EP0135532B1 Method of producing and selectively isolating proteins and polypeptides, recombinant and expression vector therefor and fusion protein able to bind to the constant region of immunoglobulins
08/10/1988CN88100542A Precursor protein of apc polypeptide, dna coding for this, and diagnostic use of dna and of protein
08/10/1988CN88100322A Activity of 2-amino-4-methyl phosphoryl butyric acid resistence gene in plant and use
08/10/1988CN87101275A Dna and its use
08/10/1988CN87100603A Vaccines against melanoma
08/09/1988US4762791 Human immune interferon
08/09/1988US4762786 Insertion of dna cloning vector comprising saccharomyces
08/09/1988US4762785 Novel method and compositions for introducting alien DNA in vivo
08/09/1988US4762784 Fermemtation process for the high level production of bovine growth hormone
08/09/1988US4762783 Process and reagent for the determination of the follicle-stimulating hormone and monoclonal antibodies suitable therefor
08/09/1988CA1240265A1 Lyophilized hepatitis b vaccine
08/04/1988DE3701623A1 Phosphinothricin-resistance gene effective in plants and its use
08/03/1988EP0277071A2 Process for the production of a human monoclonal antibody (IgG) anti-cytomegalovirus, and monoclonal antibody so obtained
08/03/1988EP0276846A2 Colony-stimulating factor derivatives
08/03/1988EP0276832A2 Process for the preparation of cetogulonic acid
08/03/1988EP0276778A2 High level expression in E. coli of soluble mature hIL-1beta and derivatives with altered biological activity
08/03/1988EP0276730A2 Cassette vector system for the expression of open reading frames in eukaryotic cells
08/03/1988EP0276723A2 Precursor protein of APC polypeptide, DNA coding therefor and diagnostic use of the DNA and protein
08/03/1988EP0276591A2 Vaccine consisting of a viral vector and recombinant DNA coding for the p25 protein of the AIDS virus
08/03/1988EP0276330A1 Recombinant plasmid dnas, coding for synthesis of polypeptide substances for a vaccine against hepatitis a
08/03/1988EP0276302A1 Nucleic acid probe assay methods and compositions.
08/03/1988EP0276287A1 Sex determination in ruminants using y-chromosome specific polynucleotides.
08/03/1988CN86106574A Human insulin analogues
08/02/1988US4761377 Human-human hybrid cell lines that produce antibodies against antigenic determinants on cancer cells
08/02/1988US4761376 Facultatively anaerobic microorganism for degrading toxic waste materials
08/02/1988US4761375 Human interleukin-2 cDNA sequence
08/02/1988US4761373 Acetohydroxyacid synthase enzyme
08/02/1988US4761371 Genetic engineering
08/02/1988US4761367 Genetic engineering
07/1988
07/28/1988WO1988005471A1 Cytotoxic lymphocyte-specific protease-related molecules and methods
07/28/1988WO1988005466A2 Tandem gene eukaryotic expression vectors
07/28/1988WO1988005465A1 Production of fibroblast growth factor
07/28/1988WO1988005464A1 PhoE PROTEIN WITH AN INSERTED ANTIGENIC DETERMINANT
07/28/1988WO1988005440A1 Peptides having immunological properties 2-hiv-2