| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 05/03/1989 | EP0313584A1 Stabilised polypeptides and their expression and use in fermentation |
| 05/03/1989 | DE3833897A1 Klonierung und expression des transforming growth faktor-(beta)2 Cloning and expression of transforming growth factor (beta) 2 |
| 05/02/1989 | US4826957 Immunogenic recombinant yeast expression product and method for purifying it |
| 05/02/1989 | US4826765 Yeast strains genetically engineered to produce wheat gluten proteins |
| 05/02/1989 | US4826764 Enhancing the translational initiation frequency of a gene |
| 05/02/1989 | US4826763 Genetically transformed saccharomyces |
| 04/27/1989 | DE3734632A1 Process for the preparation of t-PA |
| 04/26/1989 | EP0313538A2 Monoclonal antibody, a process for its preparation and the use thereof |
| 04/26/1989 | EP0313333A2 Bacterial strain |
| 04/26/1989 | EP0313156A1 SnRNP-A antigen and fragments thereof |
| 04/26/1989 | EP0313104A2 Purification, production and use of tumor necrosis factors |
| 04/26/1989 | EP0313094A2 Anticancer agent and reagent for obtaining revertants |
| 04/26/1989 | EP0313009A2 Method of gene amplification for enhancing protein production in cultured animal cells |
| 04/26/1989 | EP0312996A2 Anti-human bcdf monoclonal antibody |
| 04/26/1989 | EP0312942A2 Polypeptides with a prourokinase activity, their production and use |
| 04/26/1989 | EP0312941A2 Polypeptides with a prourokinase activity, their production and use |
| 04/26/1989 | EP0312934A2 Pichia transformation |
| 04/26/1989 | EP0312617A1 Method of obtaining polypeptides in cell-free translation system |
| 04/26/1989 | EP0312598A1 Peptide functioning to accelerate activation of protein c with thrombin |
| 04/26/1989 | EP0312540A1 Monoclonal antibodies to unreduced, nonenzymatically-glycated proteins. |
| 04/25/1989 | US4824786 Methylotroph cloning vehicle |
| 04/25/1989 | US4824782 DNA base sequence, method for preparing a recombinant plasmid including the DNA base sequence, and breeding method for enhancing the protein-secreting ability of a microorganism by introducing thereinto the recombinant plasmid |
| 04/25/1989 | US4824667 Thymidine kinase deletion mutants of bovine herpesvirus-1, vaccines against infectious bovine rhinotracheitis containing same and methods for the production and use of same |
| 04/25/1989 | CA1253093A1 Rabies vaccine and preparation process thereof |
| 04/25/1989 | CA1253092A1 Derivative of the tryptophan operon for expression of fused gene products |
| 04/25/1989 | CA1253091A1 Plasmid phjl210 and related bifunctional cloning vectors for use in streptomycetes |
| 04/24/1989 | EP0302925A4 A method for producing factor viii in high yield. |
| 04/24/1989 | EP0241539A4 Expression systems for overproduction of desired proteins. |
| 04/20/1989 | WO1989003430A1 Method to produce immunodiagnostic reagents |
| 04/20/1989 | WO1989003429A1 Recombinant avipox virus |
| 04/20/1989 | WO1989003427A1 A method of maintaining a desired recombinant gene in a genetic population of cells |
| 04/20/1989 | WO1989003426A2 Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses |
| 04/20/1989 | WO1989003425A1 Immunoglobulin gene-related dna fragment |
| 04/20/1989 | WO1989003424A1 Synthetic gene |
| 04/20/1989 | WO1989003423A1 Synthetic dna sequence coding for human insulin-like growth factor ii |
| 04/20/1989 | WO1989003422A1 Synthetic gene |
| 04/20/1989 | WO1989003421A1 Thermostable cyclodextrin glycosyl transferase, its production and use |
| 04/20/1989 | WO1989003399A1 Method of preparation and use for zona pellucida antigens and antibodies for sterilization and contraception |
| 04/20/1989 | WO1989003398A1 Human monoclonal antibody against candida |
| 04/20/1989 | WO1989003397A1 Mouse monoclonal antibodies raised to the t-cell line hsb-2 and t-cell chronic lymphocytic leukemia (t-cll) cells react with normal human t and b lymphocytes and monocytes |
| 04/20/1989 | WO1989003396A2 Antibodies to natural killer cell and non-specific cytotoxic cell receptor |
| 04/20/1989 | WO1989003226A1 Process for inactivating recombinant dna |
| 04/20/1989 | WO1989003222A1 Soluble human cd4 fragments and uses therefor |
| 04/20/1989 | WO1989002469A3 Human erythroid-specific transcriptional enhancer |
| 04/20/1989 | WO1989001783A3 Recombinant antibody and method |
| 04/19/1989 | EP0312346A2 E. coli sequence specific acid protease |
| 04/19/1989 | EP0312164A1 Purification of recombinant epstein-barr virus antigens from vero cells, yeast cells or L cells |
| 04/19/1989 | EP0312159A2 Method for producing hepatitis B virus proteins in yeast |
| 04/19/1989 | EP0312121A2 Yeast strains producing cellulolytic enzymes and methods and means for constructing them |
| 04/19/1989 | EP0312089A2 Method for producing L-threonine |
| 04/18/1989 | US4822739 Partition proficiency in genetically engineered plasmids for transforming gram-positive organisms |
| 04/18/1989 | US4822738 Transducible composite plasmid |
| 04/18/1989 | US4822736 Amplification of adenosine deaminase genes in mammalian cells using adenosine, alanosine, uridine, and deoxycoformycin |
| 04/18/1989 | US4822470 Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses |
| 04/18/1989 | CA1252948A1 Process for purifying proteins |
| 04/18/1989 | CA1252720A1 Vaccine for cytomegalovirus |
| 04/18/1989 | CA1252715A1 Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activator |
| 04/18/1989 | CA1252714A1 Diagnostic agent for heart disease and use thereof |
| 04/12/1989 | EP0311589A1 Modified tissue plasminogen activator |
| 04/12/1989 | EP0311469A2 Transformed lactic acid bacteria |
| 04/12/1989 | EP0311273A1 Transformation system for Penicillium |
| 04/12/1989 | EP0311228A2 Recombinant polypeptides and their uses, including assay for AIDS virus |
| 04/12/1989 | EP0311059A2 Cell handling apparatus |
| 04/12/1989 | EP0310913A2 DNA isolation procedure |
| 04/12/1989 | CN1032367A Dna construction with preceding sequence of kluyveromyces x-factor directing heterologous polypeptide excretion |
| 04/11/1989 | US4820642 Over production of beta-lactamase by dna; vaccine against hepatitis b |
| 04/11/1989 | US4820641 Monoclonal antibody capable of specifically distinguishing human hepato-carcinoma cells |
| 04/11/1989 | US4820639 Process for enhancing translational efficiency of eukaryotic mRNA |
| 04/11/1989 | US4820638 Novel alpha interferon species produced by recombinant means |
| 04/11/1989 | US4820630 Detecting site for restriction endonuclease enzyme; sickle cell anemia mutants; hybrid assaying |
| 04/11/1989 | US4820505 Detection of activated platelets with antibodies to thrombospondin |
| 04/11/1989 | CA1252256A1 Drain assembly with synthetic resin lock nut and coupling elements |
| 04/06/1989 | WO1989002935A1 Respiratory syncytial virus: vaccines and diagnostic assays |
| 04/06/1989 | WO1989002924A1 Vaccines for malaria |
| 04/06/1989 | WO1989002922A1 Adheson variants |
| 04/06/1989 | WO1989002921A1 Artificial dna base pair analogues |
| 04/06/1989 | WO1989002899A1 Monoclonal antibody that recognizes an epitope of the gamma chain of human t cell surface receptors |
| 04/05/1989 | EP0310586A1 Stable genomic integration and expression of a foreign coding sequence in yeast |
| 04/05/1989 | EP0310585A2 Octapeptide inhibitors of myristoylating enzymes |
| 04/05/1989 | EP0310436A2 Streptomyces expression vectors |
| 04/05/1989 | EP0310229A1 Selective amplification of target polynucleotide sequences |
| 04/05/1989 | EP0310178A1 Recovery of pres2+S antigen |
| 04/05/1989 | EP0310137A2 BAR1 secretion signal |
| 04/05/1989 | EP0310136A2 Macrophage-derived inflammatory mediator (MIP-1alpha and MIP-1beta) |
| 04/05/1989 | EP0310030A1 Cloning of DNA encoding transcription factor S-11 and utilization of the DNA |
| 04/05/1989 | EP0309969A2 Method of gene mapping |
| 04/05/1989 | EP0309961A1 Plasmid vector containing streptomycin-sensitivity gene |
| 04/05/1989 | EP0309879A2 Molecular cloning and expression of neutral protease genes |
| 04/05/1989 | EP0309862A1 Stilbene synthase gene |
| 04/05/1989 | EP0309746A1 Antimalaria vaccines |
| 04/05/1989 | EP0309569A1 Production of purified, biologically active, bacterially produced recombinant human csf-1 |
| 04/05/1989 | EP0309565A1 Subtilisin analogs. |
| 04/05/1989 | EP0309559A1 Transgenic animals. |
| 04/05/1989 | EP0309558A1 Method for detecting the expression of bioregulatory genes in microcultures of eukaryotic cells. |
| 04/05/1989 | EP0309555A1 Immunogenic polypeptide and method for purifying it |
| 04/05/1989 | EP0309548A1 Human tissue factor related dna segments, polypeptides and antibodies |
| 04/05/1989 | EP0136353B1 Serum-free animal cell culture medium and method for the primary culture and obtention of cell lines using such medium |
| 04/04/1989 | US4818700 Pichia pastoris argininosuccinate lyase gene and uses thereof |
| 04/04/1989 | US4818698 Polypeptides and preparation process thereof |
| 04/04/1989 | US4818696 Rhizobium japonicum symbiosis gene transfer |