| Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210) |
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| 01/27/1988 | EP0254315A2 Mammalian cell derived autonomously replicating sequence DNA fragments having affinity to DNA binding proteins |
| 01/27/1988 | EP0254249A1 Preparation of binding factor related polypeptides |
| 01/27/1988 | EP0254090A1 Process for recovering proteins by means of gene technology using gram-negative host cells |
| 01/27/1988 | EP0254076A1 Improved recombinant protein production |
| 01/27/1988 | EP0253912A1 Oligosaccharides, method for their manufacture and their use |
| 01/27/1988 | EP0253870A1 METHOD FOR PRODUCING FACTOR VIII:c-TYPE PROTEINS. |
| 01/27/1988 | EP0253823A1 Process for activating heterologous, eucaryotic proteins genetically engineered and presenting disulphide bridges after their expression in procaryotic cells |
| 01/27/1988 | CN87104270A Improved fusion method |
| 01/27/1988 | CN87103568A Htlv-3/lav virus related peptides, antibodies to the peptides, vaccines, passive and active immunization against aids virus |
| 01/27/1988 | CN86108579A Mammalian interleukin-4 |
| 01/26/1988 | US4721672 CDNA and gene for human angiogenin (angiogenesis factor) and methods of expression |
| 01/26/1988 | US4721671 Efficient prokaryotic expression system using portions of the E. coli .beta. |
| 01/26/1988 | US4721668 Pre-electrophoretic nucleic acid hybridization |
| 01/25/1988 | EP0195078A4 Bacillus strains with reduced extracellular protease levels. |
| 01/21/1988 | EP0187814A4 Diagnostic assay for inhibitor or tissue-type and urokinase-type plasminogen activators. |
| 01/20/1988 | EP0253693A1 Vaccine containing the AIDS virus F protein |
| 01/20/1988 | EP0253690A1 Alpha-1-antitrypsin variants particularly useful as kallikrein inhibitors |
| 01/20/1988 | EP0253646A2 Anti-human gastric cancer monoclonal antibody |
| 01/20/1988 | EP0253455A1 Method for the preparation of proteins with factor VIII activity by microbial host cells; expression vectors, host cells, antibodies |
| 01/20/1988 | EP0253325A2 Oncogene-related peptides |
| 01/20/1988 | EP0253241A1 Human prourokinase mutants, method for producing the same, DNA sequences encoding the same, plasmids containing the same and transformants containing the same |
| 01/20/1988 | EP0253193A2 Method for mutagenesis by oligonucleotide-directed repair of a strand break |
| 01/20/1988 | EP0252940A1 Anti-sense rna for treatment of retroviral disease states |
| 01/20/1988 | CN87103688A Process for obtaining chemically defined and reproducible polydeoxy-ribonucleotide |
| 01/19/1988 | US4720483 Oligopeptides and intermediates and processes for their manufacture |
| 01/19/1988 | CA1231651A1 Recombinant dna expression vectors useful in bacillus and other host cells |
| 01/14/1988 | WO1988000346A1 Monoclonal antibodies to unreduced, nonenzymatically-glycated proteins |
| 01/14/1988 | WO1988000344A1 Peptide fragments of organ-specific neoantigens |
| 01/14/1988 | WO1988000242A1 Recombinant human tissue plasminogen activator composition |
| 01/14/1988 | WO1988000241A1 Human erythropoietin gene: high level expression in stably transfected mammalian cells |
| 01/14/1988 | WO1988000239A1 Peptide production |
| 01/14/1988 | WO1988000238A1 Process for the genetic production of proteins by using of gram-negative host cells |
| 01/14/1988 | WO1988000210A1 A process for producing a coagulation active complex of factor viii fragments |
| 01/14/1988 | WO1988000209A1 gamma, delta T CELL RECEPTOR AND METHODS FOR DETECTION |
| 01/14/1988 | WO1988000208A1 Ovine inhibin |
| 01/14/1988 | WO1988000206A1 Production and use of il-6 |
| 01/14/1988 | WO1988000205A1 Novel osteoinductive compositions |
| 01/14/1988 | WO1988000204A2 Polypeptide competitor for immunoglobulin e |
| 01/14/1988 | WO1987007302A3 MONOCLONAL ANTIBODIES TO HUMAN LYMPHOCYTE IgE RECEPTORS, HYBRIDOMAS PRODUCING SUCH ANTIBODIES, AND KITS FOR USING SUCH ANTIBODIES |
| 01/13/1988 | EP0252894A2 Hybrid polypeptides comprising somatocrinine and alpha-antitrypsine, process for their production from bacterial clones and their use in the production of somatocrinine |
| 01/13/1988 | EP0252854A1 Functional DNA block and plasmid coding for hirudine, transformed yeast and process for the preparation of hirudine. |
| 01/13/1988 | EP0252774A1 Saccharomyces strains producing alpha-amylase |
| 01/13/1988 | EP0252741A2 Use of a monoclonal antibody against the 17-1A antigen for the manufacture of a medicament for the treatment of a gastrointestinal tumor |
| 01/13/1988 | EP0252737A2 Improved strains of yeast for the expression of heterologous genes |
| 01/13/1988 | EP0252685A2 Diagnostic methods for detecting lymphomas in humans |
| 01/13/1988 | EP0252683A2 Process and reagents for DNA sequence analysis |
| 01/13/1988 | EP0252666A2 Chimeric Enzymes |
| 01/13/1988 | EP0252561A2 Expression and secretion vector in yeasts, useful for preparing heterologous proteins |
| 01/13/1988 | EP0252558A2 Element of dna of corynebacterium diphteriae with typical properties of an is insertion element |
| 01/13/1988 | EP0252531A1 Structural phosphoprotein (pp 150) of human cytomegalovirus, its preparation and use |
| 01/13/1988 | EP0252302A1 Major glycoprotein of human cytomegalo virus, its preparation and use |
| 01/13/1988 | EP0252146A1 Nuclear factors associated with transcriptional regulation. |
| 01/13/1988 | EP0252098A1 ASEXUAL BLOOD STAGE ANTIGENS OF $i(PLASMODIUM FALCIPARUM) |
| 01/13/1988 | CN87102457A Immortalization of primary cells |
| 01/12/1988 | US4719180 Genetic engineering |
| 01/12/1988 | US4719179 Six base oligonucleotide linkers and methods for their use |
| 01/12/1988 | US4719177 Genetic engineering |
| 01/12/1988 | CA1231314A1 Plasmids for foreign gene expression in b. subtilis |
| 01/07/1988 | EP0252060A1 DNA sequence, recombinant DNA molecules, and method for the production of the Newcastle disease virus fusion protein or equivalent polypeptides, products obtained and preparations containing them |
| 01/07/1988 | EP0251933A1 Peptide having antigenic properties isolated from the S. Mansoni 28KD proteingroup and its isolation process, monoclonal antibodies recognizing at least one epitope of that peptide, and uses in the induction of neutralizing antibodies synthesis |
| 01/07/1988 | EP0251874A1 Integration vectors for the expansion of factor IX in eucaryotic cells, cell lines obtained and method for their preparation |
| 01/07/1988 | EP0251842A1 Composite DNA sequence and its use in the production of a growth hormone |
| 01/07/1988 | EP0251786A2 Alkynylamino-nucleotides |
| 01/07/1988 | EP0251744A2 Process for the genetic modification of yeast |
| 01/07/1988 | EP0251730A2 Production of human lysozyme |
| 01/07/1988 | EP0251654A2 Transformation of chloroplasts |
| 01/07/1988 | EP0251635A2 Monoclonal antibodies and method for detecting dioxins and dibenzofurans |
| 01/07/1988 | EP0251612A2 Human monoclonal antibody to lymphadenopathy-associated virus |
| 01/07/1988 | EP0251579A2 Non-antibiotic marker system |
| 01/07/1988 | EP0251575A1 Hepatitis delta diagnostics and vaccines, their preparation and use |
| 01/07/1988 | EP0251554A2 A Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin |
| 01/07/1988 | EP0251534A1 Varicella-zoster virus as a live recombinant vaccine |
| 01/07/1988 | EP0251510A1 A new tylosin resistance-conferring gene, designated tlrB for use in streptomyces and other organisms |
| 01/07/1988 | EP0251467A2 Compositions and methods of use for a major outer capsid protein (VP7) of rotavirus SA-11 |
| 01/07/1988 | EP0251460A2 Method for producing hepatitis B virus core antigen (HBcAg) in yeast |
| 01/07/1988 | EP0251449A2 Recombinant alveolar surfactant protein |
| 01/07/1988 | EP0251446A2 Non-human Carbonyl hydrolase mutants, DNA sequences and vectors encoding same and hosts transformed with said vectors |
| 01/07/1988 | EP0251440A2 Human anti-Rhesus D producing heterohybridomas |
| 01/07/1988 | EP0251320A2 Microorganisms for degrading toxic waste materials |
| 01/07/1988 | EP0251283A2 Poly-labelled oligonucleotide derivative |
| 01/07/1988 | EP0251244A2 Polypeptide and production thereof |
| 01/07/1988 | EP0251195A2 Method and reagent for the determination of alpha-amylase |
| 01/07/1988 | EP0251107A2 Improved fusion products |
| 01/07/1988 | EP0251106A2 Improved fusion method |
| 01/07/1988 | EP0251065A2 Enhanced production of antibodies utilizing insolubilized immune complexes |
| 01/07/1988 | EP0251064A1 A vector plasmid suited for souring agents, dairy souring agents in particular |
| 01/07/1988 | EP0251037A2 Novel human TNF polypeptide mutants and DNAs encoding said mutants |
| 01/07/1988 | EP0250614A1 DNA fragments encoding the chromosomal nucleotide sugar synthetases and glycosyl transferases |
| 01/07/1988 | EP0250523A1 Fermentation processes |
| 01/07/1988 | EP0103000B1 Method for determination of tissue types coded by mhc genes |
| 01/05/1988 | US4717666 Cloned streptomycete lividans excretable β-galactosidase gene |
| 01/05/1988 | US4717653 Comparing dna and rna segments, chromatography, hybrids, endonuclease digestion |
| 01/05/1988 | CA1231068A1 Cloning vectors for expression of exogenous protein |
| 01/05/1988 | CA1231067A1 Monoclonal antibody to peroxidase and hybridoma producing it |
| 12/30/1987 | WO1987007912A1 Method for detecting in seropositive individuals dna sequences of the retrovirus htlv iii-lav and kit for implementing such method |
| 12/30/1987 | WO1987007910A1 Bradyrhizobium japonicum nodulation regulatory protein and gene |
| 12/30/1987 | WO1987007909A1 Light inducible promoter |
| 12/30/1987 | WO1987007908A1 Vaccines containing epitopes of both the csp and a blood stage antigen of a plasmodium parasite |
| 12/30/1987 | WO1987007907A1 Process for the production of a protein |
| 12/30/1987 | WO1987007896A1 T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen |