Patents
Patents for C12N 15 - Mutation or genetic engineering; Dna or rna concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor (402,210)
05/1989
05/24/1989DE3737367A1 Vascular anticoagulant proteins, DNA which encode the latter, process for their preparation and their use
05/24/1989CN1033074A Monoclonal antibody specific to a novel epitope of the lfa-1 antigen of human t lymphocytes
05/24/1989CN1033072A Recombinant dna-derived bordetella toxin subvnit analogs
05/24/1989CN1033071A Monoclonal antibody specific to hiv antigens
05/24/1989CN1033070A Modified plasminogen activators
05/23/1989US4833332 Scanning fluorescent detection system
05/23/1989US4833239 Method for the isolation and purification of DNA molecules
05/23/1989US4833086 Plasmids, pollution control, culture of alcaligenes, ethylene dchloride
05/23/1989US4833085 Monoclonal antibody specific for human colon fibroblast-derived t-PA
05/23/1989US4833080 Regulation of eucaryotic gene expression
05/23/1989US4833071 Peptide composition as anitgen for detection of antibodies to HTLV-I, as a vaccine for ATL and methods therefor
05/23/1989US4832959 Preparation of polypeptides having human γ-interferon activity
05/23/1989CA1254527A1 Expression vectors for enhanced production of polypeptides, plasmids containing the vectors, hosts containing the plasmids, products manufactured thereby and related methods
05/23/1989CA1254526A1 Enhancement of nucleic acid hybridization by anionic polymers
05/18/1989WO1989004491A1 Urinary assay for measuring bone resorption
05/18/1989WO1989004486A1 Diagnostic methods and systems for quantifying apo ai
05/18/1989WO1989004376A1 Monoclonal antibody specific to hiv antigens
05/18/1989WO1989004371A1 Plants genetically enhanced for disease resistance
05/18/1989WO1989004370A1 Human monoclonal anti-hiv-i-antibodies
05/18/1989WO1989004368A1 Novel human tissue-type plasminogen activator variant
05/18/1989WO1989004367A1 Method of purifying recombinant proteins from corresponding host cell proteins
05/18/1989WO1989004365A1 Microorganism having low acetate forming capability and its application
05/18/1989WO1989004327A1 Human monoclonal antibody against aspergilli
05/18/1989WO1989004326A1 Alveolar surfactant proteins
05/18/1989WO1989004320A1 PRODUCTION OF ANIMAL LYSOZYME c VIA SECRETION FROM PICHIA PASTORIS AND COMPOSITION THEREFOR
05/18/1989WO1989004209A1 Emulsifiers
05/18/1989WO1989004175A1 Monoclonal antibody specific to a novel epitope of the lfa-1 antigen of human t lymphocytes
05/18/1989WO1989004174A1 Anti-c3bi receptor (cr3) antibodies and therapeutic composition
05/18/1989WO1989003846A3 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
05/17/1989EP0316306A2 Monoclonal antibodies special for HB A1c
05/17/1989EP0316229A1 Microorganism having low acetate forming capability, and process for production of useful substrate using same
05/17/1989EP0316170A2 Method for the identification of antigens expressed in vivo, diagnostic assays therefor and vaccines containing them
05/17/1989EP0316115A2 Novel voctors and expression sequences for production of polypeptides
05/17/1989EP0316068A1 Modified low molecular weight plasminogen activator and method of preparation
05/17/1989EP0316018A2 Modification of DNA sequences
05/17/1989EP0316016A2 Modified oligonucleotides
05/17/1989EP0315949A2 A method for microbiological reaction
05/17/1989EP0315944A2 Controlled growth rate fermentation
05/17/1989EP0315782A2 Method for the production of proteins
05/17/1989EP0315683A1 Dna sequences, recombinant dna molecules and processes for producing lymphocyte function associated antigen-3
05/17/1989EP0315650A1 Purification of recombinant interleukin-1.
05/16/1989US4831124 Recombinant cDNA construction method and hybrid nucleotides useful in cloning
05/16/1989US4831120 Method for recovering a purified animal growth hormone or polypeptide analog thereof from a bacterial cell
05/16/1989US4830969 Process for the rapid and simple isolation of nucleic acids
05/16/1989US4830965 Dna sequence contains endonuclease recognition sites and base pair attachment sites for mu bacteriophage genome
05/16/1989US4830962 Expression vectors encoding for a dt-a fragment which use dna control sequences not native to the coding sequences but compatible to the host
05/16/1989EP0275298A4 Dmd probes.
05/16/1989EP0228452A4 Protein purification.
05/16/1989CA1254161A1 Herpes virus specific immunological materials and methods
05/16/1989CA1254114A1 Displacement polynucleotide assay employing recombination protein and diagnostic kit
05/11/1989EP0217822A4 Human metallothionein-ii promoter in mammalian expression system.
05/10/1989EP0315456A2 Polysaccharide-modified immunoglobulins having reduced immunogenic potential or improved pharmacokinetics
05/10/1989EP0315254A1 Protein 7B2, recombinant DNA, cDNA and mRNA, and a method of detecting the mRNA
05/10/1989EP0315118A2 DNA coding for endothelin and use thereof
05/10/1989EP0315085A2 Recombinant histidine-rich protein from Plasmodium falciparum, its synthesis and use
05/10/1989EP0315081A2 Anti-coagulating protein PP4-x, its preparation and use
05/10/1989EP0315062A2 Production of chimeric antibodies by homologous recombination
05/10/1989EP0314862A1 Immunogenic conjugates comprising cyclosporins
05/10/1989EP0314861A1 Labeled derivatives of cyclosporins
05/10/1989EP0314744A1 Monokine dosing.
05/10/1989CN1032816A Monoclonal antibodies against human interleukin-4 and hybridomas producing same
05/09/1989US4828994 Genetic engineering, cloning vector, mutants, spores
05/09/1989US4828990 Zinc or copper salt, polyethylenimine
05/09/1989US4828988 Hybrid polypeptides comprising somatocrinine and alpha1 -antitrypsin, method for their production from bacterial clones and use thereof for the production of somatocrinine
05/09/1989US4828987 Avian retrovirus-bovine growth hormone DNA
05/09/1989US4828986 Elisa; monoclonal paratopic molecules secreted by hydbridomas to immunoreact
05/09/1989US4828981 Competitive, homogeneous or heterogeneous
05/09/1989US4828979 Biotinylated
05/09/1989CA1253816A1 Monoclonal antibodies against alveolar surfactant protein
05/09/1989CA1253777A1 Nucleic acid hybridization assay employing immobilized rna probes
05/05/1989WO1989003996A1 Human gamma, delta t cell antigen receptor polypeptides and nucleic acids
05/05/1989WO1989003993A1 Paired helical filament core and antibody thereto useful in diagnosing alzheimer's disease
05/05/1989WO1989003887A1 A process for the production of biologically active peptide via the expression of modified storage seed protein genes in transgenic plants
05/05/1989WO1989003886A1 Expression systems for preparation of polypeptides in prokaryotic cells
05/05/1989WO1989003884A1 Interleukin-7
05/05/1989WO1989003883A1 Enhancement of cell growth by expression of a cloned hemoglobin gene
05/05/1989WO1989003882A1 Multiple promoter transforming retroviral vectors
05/05/1989WO1989003881A1 Nonglycosylated analogs of human colony stimulating factors
05/05/1989WO1989003880A1 A gene coding for glucuronide permease
05/05/1989WO1989003879A1 Fowlpox virus promoters
05/05/1989WO1989003878A1 Defective recombinant gene which can be activated by a transactivator
05/05/1989WO1989003877A1 Integration and expression viral vectors
05/05/1989WO1989003874A1 Novel polypeptide compounds
05/05/1989WO1989003872A1 Generation of neural precursor cell lines
05/05/1989WO1989003846A2 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
05/05/1989WO1989003845A1 Ps2 protein derivative
05/03/1989EP0314569A1 Recombinant fowlpox virus, expression vectors for heterologous proteins, and vaccines for fowl derived from this virus
05/03/1989EP0314534A1 Expression vector for proteins from the HIV-2 virus, one of the agents that cause AIDS
05/03/1989EP0314500A2 Diagnostic probe for diabetes type 1 predisposition
05/03/1989EP0314415A2 Interleukin-7
05/03/1989EP0314402A2 Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
05/03/1989EP0314346A1 Method for producing the Afl II restriction endonuclease
05/03/1989EP0314317A1 Adheson variants, nucleic acid encoding them and compositions comprising them
05/03/1989EP0314294A2 Detection of listeria
05/03/1989EP0314274A2 Improved promoter, vector having the improved promoter, plasmid having the vector, and E.coli transformed with the plasmid
05/03/1989EP0314202A1 The isolation of mRNA
05/03/1989EP0314184A1 Expression plasmids
05/03/1989EP0314161A1 Human immunoglobulines produced by recombinant DNA techniques
05/03/1989EP0314096A2 Methods of regulating protein glycosylation
05/03/1989EP0314094A2 Recombinant lymphotoxin