Patents
Patents for C07H 23 - Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin b12 (1,716)
09/2006
09/14/2006US20060205677 Diammine and bis(cyclohexanediamine) complexes of platinium malonates containing glucopyranosyl, mannopyranosyl, galactopyranosyl or glucurony groups [1R,2R-Cyclohexanediamine-N, N'][{2-( beta -D-Glucopyranos-1-ylamido)ethyl}propanedioato(2-)-O,O']Platinum(II); good water solubility
09/06/2006EP1697397A1 Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation
09/05/2006US7101993 Oligonucleotides containing 2′-O-modified purines
08/2006
08/17/2006US20060183877 Reacting a bis-, tris- or tetrakis(halo- or hydrocarbylsulfonyloxyhydrocarbylsiloxysilane with an alkali or alkaline earth metal salt of a mercaptoalkyl-substituted saccharide to form a bis-, tris- or tetrakis(saccharide-alkylthiohydrocarbylsiloxy)silane
07/2006
07/27/2006US20060167237 Derivatives of monosaccharides for drug discovery
07/27/2006US20060166862 Comprising a transcobalamin (TC) binding carrier and a therapeutic and/or diagnostic agent linked directly or through linker to the TC binding carrier; highly and efficiently absorbed
07/27/2006US20060166197 Building block capable of transferring a functional entity
07/25/2006CA2253330C 6-o-substituted erythromycin compounds and method for making same
07/18/2006US7078517 Using acid/alkali hydrolysis to recycle matrix comprising oligonucleotides immobilized via acid-amido bonding; reusable solid support for nucleotide sequences analysis
07/18/2006CA2267133C Methods for labeling nucleotides, labeled nucleotides and useful intermediates
06/2006
06/15/2006WO2006061685A1 A cost-effective process for preparation of manufacture of iron sucrose
06/08/2006US20060122126 (1S)-1,5-anhydro-1-[3-(1-benzothiene-2-ylmethyl)phenyl-D-glucitol and derivatives are Na+-glucose cotransporter inhibitors and are used to treat diabetes and related diseases such as insulin-resistance and obesity
05/2006
05/30/2006CA2165971C Methylphosphonic acid ester, process for preparing the same and its use
05/24/2006CN1775792A Gemini boric acid ester glucose acylamine compound, and its preparing method and use
05/23/2006CA2351207C Radionuclide labeling of vitamin b12 and coenzymes thereof
05/02/2006CA2250771C 9-oximesilyl erythromycin a derivatives
04/2006
04/25/2006US7034035 Having a high residual activity, greater activity at lower application rates, curative activity, and a broader spectrum of efficacy; heterocyclic aromatic amides having a hydroxy group adjacent to the amide functionality
04/25/2006US7033760 Metallic solid supports modified with nucleic acids
04/18/2006US7030105 Method of synthesis of β-thiolato cobalamin compounds
04/12/2006EP1270017B1 Radiolabeled pyrimidine nucleoside for the diagnosis of tissue-reproductive activity
04/06/2006US20060074034 Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
04/05/2006CN1249058C Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use
03/2006
03/14/2006CA2326684C Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
03/09/2006US20060051323 Formulations comprising vitamin b12, method of production and use thereof
03/01/2006EP1236737B1 Process for production of methylcobalamin
03/01/2006EP1186059B1 Method for forming monolayers
02/2006
02/23/2006CA2575706A1 Vitamin b12 compositions
02/22/2006EP0549615B1 Sugar modified oligonucleotides that detect and modulate gene expression
02/21/2006US7001724 Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases
02/15/2006EP1625138A2 Protected monomers
01/2006
01/25/2006EP1474430B1 Bi-functionalised metallocenes use for marking biological molecules
01/18/2006CN1237051C Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
01/17/2006CA2351829C Macrolide antibiotics
01/03/2006CA2135852C 5-methyluridine process for large-scale preparation of 2',3'-didehydro-3'-deoxythymidine (d4t)
12/2005
12/21/2005CN1711036A Formulations comprising vitamin B12, method of production and use thereof
12/08/2005WO2005116046A1 Method for producing an iron sucrose complex
12/08/2005WO2005116040A1 Process for preparing an iron saccharose complex
12/06/2005CA2235942C Tricyclic erythromycin derivatives
11/2005
11/29/2005CA2164704C Use of cobalamins for topical treatment of dermatological illnesses
11/17/2005US20050256031 Composition for relieving discomfort
11/10/2005US20050249663 Coadministration of transport protein with conjugated cobalamin to deliver agents
11/02/2005EP0923595B1 Nucleic acid mediated electron transfer
10/2005
10/11/2005US6953850 Protecting groups for carbohydrate synthesis
10/06/2005US20050221318 Building block forming a c-c bond upon reaction
09/2005
09/29/2005US20050214759 Enzymatic redox labelling of nucleic acids
09/28/2005CN1675232A Derivatives of monosaccharides for drug discovery
09/21/2005EP1575382A2 Formulations comprising vitamin b12, method of production and use thereof
09/21/2005CN1219551C Conjugates made of metal complexes and oligonucleotides
09/01/2005WO2005080490A1 A solution of metal-polymer chelate(s) and applications thereof
09/01/2005WO2005080489A1 A solution of metal-polymer chelate(s) and applications thereof
08/2005
08/31/2005CN1660883A Polyglycol modified trisilicate containing glucose amide group and preparation method
08/31/2005CN1660882A Method for preparing oxane trisilicate of containing glucosyacylamino
08/18/2005US20050181430 Rapid nucleic acid assay
08/11/2005US20050176948 Libraries; locked nucleic acids; peptide nucleic acids
08/09/2005US6927225 Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation
07/2005
07/28/2005US20050165227 Antiproliferative agents; gene overexpression
07/26/2005US6921818 Using silyl compositions that can be directly coupled, or coupled through linking group, to compound of interest, preferably to oligomer at end of oligomer synthesis; silicon atom includes 1-3 sidechains that function as capture tags
07/19/2005US6919439 Derivatized oligonucleotides having improved uptake and other properties
07/07/2005WO2005061527A1 Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation
07/07/2005CA2550657A1 Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation
06/2005
06/29/2005CN1208321C Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
06/22/2005EP1007533B1 Bioconjugates and delivery of bioactive agents
06/15/2005EP1539780A1 Derivatives of monosaccharides for drug discovery
06/02/2005US20050118621 Methods for labeling nucleotides, labeled nucleotides and useful intermediates
05/2005
05/31/2005US6900297 A compound which hybridizes with a nucleic acid includes multiple inked nucleosides (inlcudes a pentofuranosyl sugar portion and a base portion), and at least one sugar o-is terminated with R-N(R1a R1b) substitutent
05/31/2005US6900180 Mixture of folic acid, vitamin b6 and b12 with carbohydrates, fats and proteins; infant formula; sleep disorders
05/10/2005US6890712 Cycling DNA/RNA amplification electrochemiluminescent probe assay
04/2005
04/28/2005WO2005014609A3 Method of producing a highly stereoregular phosphorus atom-modified nucleotide analogue
04/27/2005EP1143974B1 Pharmaceutical compositions for alleviating discomfort
04/20/2005EP1307446B1 Perfluoroalkyl-containing complexes comprising sugar residues, method for producing the same and use thereof
04/14/2005US20050080042 synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids; Vascular thrombosis, cardiovascular disease
03/2005
03/31/2005US20050069493 Administering a cobalamin linked with a diamino compound to a chelating group of a detectable metal, such as a radionuclide or paramagnetic metal ion
03/24/2005WO2005026188A1 Metal complex type nucleic acid
03/24/2005US20050064494 Chemically modified biological molecules and methods for coupling biological molecules to solid support
03/22/2005US6870039 Synthesizing phosphorothioate oligonucleotides and their intermediates; used in genomic research as probes, primers and alsoin diagnositics
03/17/2005WO2005023829A1 Metal complex type nucleic acid
03/16/2005EP0716604B1 Thiol-derivatized nucleosides and oligonucleosides
03/09/2005EP1075544A4 Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
03/02/2005EP1509533A1 Polyol-modified silanes as precursors for silica
03/02/2005EP1165563B1 Bicyclic heterocycles, method for producing them and their use as herbicides and pharmaceutical agents
02/2005
02/24/2005US20050043365 Reaction productof 4-acetylthiobutyl-2,3,4,6-tetra-O-acetyl beta D-glucopyranoside with terakis(bromopropyldimethylsiloxy)silane
02/22/2005US6858713 DNA, RNA, protein, saccharide or lipid modified with an epoxysilane compound; can be readily affixed to solid supports, for instance, a glass surface, without first derivatizing the glass surface
02/17/2005WO2005014609A2 Method of producing a highly stereoregular phosphorus atom-modified nucleotide analogue
02/17/2005US20050038184 Reaction product of 4-acetylthiobutyl 2,3,4,6-tetra-O-acetyl- beta -D-glucopyranoside and tetrakis(bromopropyldimethylsiloxy)silane
02/09/2005EP1504010A1 Vitamin-mitomycin conjugates
02/03/2005US20050027116 Includes a hydroxyl-containing compound bound to support by disiloxyl linkage; combinatorial chemistry; oligonucleotide biosynthesis
02/01/2005US6849607 Galectin recognized photosensitizers for photodynamic therapy
01/2005
01/06/2005US20050004010 Complex with antitumor agents; therapy, diagnosis
12/2004
12/29/2004EP1490384A2 A building block forming a c-c bond upon reaction
12/29/2004CN1558911A Synthetic heparin pentasaccharides
12/23/2004US20040259810 Porphyrin derivatives for photodynamic therapy
12/22/2004EP1487851A2 A building block capable of functional entity transfer to nucleophil
12/22/2004EP1487849A2 A building block capable of transferring a functional entity
12/15/2004CN1555382A Association compound of trehalose or maltitol with metal ion compound
10/2004
10/21/2004US20040209841 Association compound of trehalose or maltitol with metal ion compound
10/20/2004EP1468006A1 Enzymatic redox labelling of nucleic acids
10/13/2004EP1173184B1 para-BORONOPHENYLALANINE COMPLEXES WITH FRUCTOSE AND RELATED CARBOHYDRATES AND POLYOLS
10/13/2004CN1170841C Process for production of methylcobalamin
09/2004
09/28/2004US6797818 Methods for labeling nucleotides, labeled nucleotides and useful intermediates
09/15/2004EP1032708A4 Nucleic acid ligands of tissue target
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