Patents
Patents for C07H 23 - Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin b12 (1,716)
08/2000
08/31/2000WO2000050431A1 Platinum (ii) compounds
08/31/2000CA2364712A1 Platinum (ii) compounds
08/01/2000US6096904 Discodermolides
08/01/2000US6096290 Radionuclide labeling of vitamin B12 and coenzymes thereof
07/2000
07/27/2000WO2000043013A1 Pharmaceutical compositions for alleviating discomfort
07/27/2000WO2000042868A1 Infant formula
07/27/2000CA2627837A1 Pharmaceutical compositions for alleviating discomfort
07/20/2000WO2000042057A1 Protecting groups for carbohydrate synthesis
07/11/2000US6087100 Nucleic acid mediated electron transfer
07/06/2000WO2000039142A1 Erythromycin a compounds and process for preparing the same
07/05/2000EP1015475A1 Vitamin b 12? receptor modulating agents and methods related thereto
07/04/2000US6083926 Water soluble vitamin B12 receptor modulating agents and methods related thereto
06/2000
06/27/2000US6080591 Useful in biological assays for determination of vitamin b12, folate, cortisol, estradiol, and thromboxane b2
06/14/2000EP1007533A1 Bioconjugates and delivery of bioactive agents
06/07/2000EP1005478A1 Ribonucleoside-derivative and method for preparing the same
06/06/2000US6071699 Nucleic acid mediated electron transfer
05/2000
05/23/2000CA2079448C Lanthanide chelate-conjugated oligonucleotides
04/2000
04/19/2000CN1051560C Method for preparing chelate of antibiotic and complex metallic salt
04/18/2000CA2182578C Halogenated derivatives of 2,3'-o-cyclocytidine compounds and process for production thereof
04/13/2000WO2000020428A2 Synthesis of oligosaccharides, reagents and methods related thereto
04/13/2000CA2346237A1 Synthesis of oligosaccharides, reagents and methods related thereto
04/11/2000US6048695 Nucleic acid modified by addition of epoxide-alkoxysilane compound for immobilization to unmodified or underivatized glass surface; for hybridization microarrays for genome-wide genetic mapping and gene expression studies
04/11/2000US6048687 Detecting nucleotide sequence; obtaining sample, mixing sample with reagent, incubating sample with reaction mixture to amplify nucleotide sequence, obtaining samples, adding probe, incubating with second mixture and detecting complex
04/11/2000CA2090301C New sulfated diosmin derivative
04/05/2000EP0989991A1 Purification of oligomers
02/2000
02/29/2000US6031133 Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof
02/22/2000US6028182 Methylphosphonic acid esters, processes for their preparation, and their use
02/08/2000CA1340893C Immuno chemical determination using non-metallic sol labelling
02/03/2000WO2000004865A2 Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
02/03/2000CA2338310A1 Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives
02/02/2000EP0976757A2 A method of purifying vitamin B12 and/or derivatives thereof
01/2000
01/26/2000EP0973785A1 Trans-platinum compound, and diagnostic kit
01/20/2000WO2000002894A1 Silicon-containing linkers for nucleic acid mass markers
01/20/2000WO2000002893A1 Metal ion-binding mass markers for nucleic acids
01/20/2000CA2385970A1 Silicon-containing linkers for nucleic acid mass markers
01/20/2000CA2385962A1 Metal ion-binding mass markers for nucleic acids
01/12/2000EP0969829A1 Synthetic techniques and intermediates for polyhydroxy, dienyllactones and mimics thereof
01/04/2000US6011143 Artificial nucleic acids and a method of making
12/1999
12/28/1999CA2114922C Organosilicon compounds containing glycoside radicals and processes for their preparation
12/23/1999WO1999065930A1 Vitamin b12 derivatives and methods for their preparation
12/23/1999CA2334598A1 Vitamin b12 derivatives and methods for their preparation
12/21/1999US6005087 Nuclease resistant oligonucleotides which are useful as therapeutics, diagnostics, and research reagents for various viral diseases
12/21/1999US6004533 Radionuclide labeling of vitamin B12 and coenzymes thereof
12/14/1999US6001982 Synthesis of oligonucleotides
12/07/1999US5998135 Energy transfer hybridization assay using intercalators and lanthanide metals
11/1999
11/16/1999US5986090 Metallized porphyrins
11/16/1999US5986084 Nucleoside with triple substituted silyloxymethyl group as a protection group on the 2' oxygen; protection groups are not subject to isomerization and give higher coupling yields
11/16/1999US5985566 Detectable labels
11/11/1999WO1999057323A1 Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
11/10/1999EP0531447B1 Compositions and methods for modulating rna activity through modification of the 5' cap structure of rna
10/1999
10/27/1999EP0951842A2 Infant formula
10/20/1999CN1045772C Polyazacycloalkanes as dichelants
10/12/1999US5964224 Method for treating amyotrophic lateral sclerosis and a therapeutic agent therefor
09/1999
09/21/1999US5955601 Useful in nucleic acid hybridization assays and for generating labelled probes; unusually high efficiency of rare earth element capture correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy
09/14/1999US5952478 Nucleotides and analogs in which both the 3' oxy linkage and the 5' oxy linkage are replaced by carbon linkages; for antisense agents; viricides against influenza, herpes and human immune deficiency virus; anticarcinogenic agents
09/14/1999US5952172 Alternating current input signal to a hybridization complex with single stranded nucleic acid containing a covalently attached electron transfer moiety and electrode, detecting target sequence via output signal
08/1999
08/25/1999EP0937090A1 Methods for labeling nucleotides, labeled nucleotides and useful intermediates
08/11/1999EP0722508A4 Self-sustained sequence replication electrochemiluminescent nucleic acid assay
08/04/1999CN1044476C Chelate and preparation thereof
07/1999
07/01/1999WO1999032501A1 Compounds for mass spectrometry comprising nucleic acid bases and aryl ether mass markers
06/1999
06/30/1999EP0925306A1 Solid phase synthesis
06/24/1999WO1999031115A1 Conductive metal-containing nucleic acids
06/23/1999EP0923595A1 Nucleic acid mediated electron transfer
06/23/1999EP0923591A1 Novel boronic acid-containing nucleic acids and their use as diagnostic agents
06/16/1999EP0757690A4 Electron-deficient porphyrins and processes and intermediates for preparing same
06/09/1999EP0920439A1 Nucleic acids internally-derivatized with a texaphyrin metal complex and uses thereof
06/03/1999WO1999027138A1 Nucleic acid ligands of tissue target
06/03/1999CA2311164A1 Nucleic acid ligands of tissue target
06/02/1999EP0918789A1 Pyridine nucleotide-dependent enzymes
05/1999
05/26/1999EP0917533A2 Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
05/12/1999EP0799237B1 Vitamin b 12-containing sallow thorn concentrates or extracts
04/1999
04/21/1999EP0909184A2 Targeted drug delivery using sulfonamide derivatives
04/21/1999EP0543889B1 Incorporation of selectably clevable sites into oligonucleotide chains and reagents therefor
03/1999
03/24/1999EP0810878B1 Rna photocleavage using texaphyrins
03/10/1999EP0900805A2 Incorporation of selectably cleavable and/or abasic sites into oligonucleotide chains and reagents therefor
03/02/1999US5876938 Use of boron-containing polynucleotides as diagnostic agents
02/1999
02/25/1999WO1999009044A1 Ribonucleoside-derivative and method for preparing the same
02/16/1999US5872232 2'-O-modified oligonucleotides
02/16/1999US5872107 Anticarcinogenic agents capture therapy for tumors
02/09/1999US5869465 Binding to cell surface receptors and affecting their trafficking pathway for the treatment and diagnosis of disorders in warm-blooded animals
01/1999
01/19/1999CA2037663C Use of complexes and chelates resp., of antibiotics with bivalent and/or trivalent metals in the obtaining of anti-ulcer drugs, new complexes and chelates resp., of antibiotics with bivalent and/trivalent metals and processes for the obtaining thereof
01/12/1999US5859221 Hybrid dna, rna; nuclease resistant
01/07/1999WO1999000402A1 Purification of oligomers
01/07/1999CA2294617A1 Purification of oligomers
01/05/1999US5856515 Electron-deficient porphyrins and processes and intermediates for preparing same
01/05/1999US5856466 Coupling 2'-o-alkylated guanosine 3'-o-phosphoramidite with a 5'-hydroxyl moiety on an oligonucleotide
12/1998
12/30/1998EP0766688A4 Synthesis of oligonucleotides
12/22/1998US5852188 Oligonucleotides having chiral phosphorus linkages
12/22/1998US5852182 Thiol-derivatized oligonucleosides
12/16/1998EP0883627A1 Radionuclide labeling of vitamin b12 and coenzymes thereof
12/16/1998CN1041166C Use of complexes and chelates resp., of antibiotics with bivalent and/or trivalent metals in obtaining of antiulcer, complexes and chelates
12/08/1998US5847106 Monomeric and dimeric nucleosides with silyl-containing diamino phosphorous linkages
11/1998
11/24/1998US5840880 Receptor modulating agents
11/24/1998US5840712 Water soluble vitamin B12 receptor modulating agents and methods related thereto
11/10/1998US5834448 Dosage form of hydroxocobalamin and its use in cyanide poisoning
11/03/1998US5831080 Process for preparing organosilicon compounds containing glycoside radicals
11/03/1998US5831073 Ion triggered alkylation of biological targets by silyloxy aromatic agents
11/03/1998US5831046 Boronic acid-contaning nucleic acid monomers
11/03/1998US5831045 Boronic acid-containing polynucleotides
10/1998
10/21/1998EP0871642A1 Nucleic acid mediated electron transfer
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18