Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
09/2008
09/25/2008US20080233587 buffer formulation allows for minimal sample purification; direct buffer comprises at least 5 PCR primer pairs, Tris-HCl at 10-16 mM, KCl at 25-75 mM, dNTPs at 200-400 uM each dNTP, BSA at 160-960 ug/ml, AmpliTaq Gold polymerase at 2 U-8 U, MgCl2 at 1.25-2.2 mM, and DMSO at 0-4%.
09/25/2008US20080233582 Single nucleotide polymorphisms associated with susceptibility to cardiovascular disease
09/25/2008US20080233579 Primer set for detecting overexpression of katp channel and kit comprising said primer set
09/25/2008US20080233570 Oligonucleotide primer for rapid identification and quantification of microorganisms; blood toxemia; obtaining amplification products using primer pairs that hybridize to ribosomal RNA and housekeeping gene; comparing base compositions to known amplification products of sepsis-causing bacteria
09/25/2008US20080233567 Companion diagnostic assays for cancer therapy
09/25/2008US20080233566 Methods and materials for detecting mutations in quasispecies having length polymorphisms
09/25/2008US20080233565 PKHDL1, a homolog of the autosomal recessive kidney disease gene
09/25/2008US20080233563 Enhanced Detection of Rna Using a Panel of Truncated Gene-Specific Primers for Reverse Transcription
09/25/2008US20080233558 Inhibitors of viral entry screening method
09/25/2008US20080233557 can accurately detect mutations of rtL180M, rtM204V, rtM204I and rtV2071 within B and C domains of HBV DNA polymerase gene; kits
09/25/2008US20080233147 Circovirus sequences associated with piglet weight loss disease (PWD)
09/25/2008US20080233146 Promoter gene, recombinant turkey herpesvirus having the novel promoter gene, and poultry vaccine including the recombinant herpes virus of turkey
09/25/2008US20080233139 Polypeptide comprising major histocompatibility complex epitopes for use in targeting and destroying tumor cells
09/25/2008US20080233134 Antibodies That Specifically Bind to Chemokine Beta-4
09/25/2008US20080233133 Specified complementary determining region (CRD) amino acid sequences; specific binding activity for a cryptic collagen epitope; angiogenesis inhibition, antimetastasis, and tumor-targeted therapy uses
09/25/2008US20080233126 G Proteins, Polynucleotides Encoding the Same and Utilization Thereof
09/25/2008US20080233124 Compositions and methods for the therapy and diagnosis of ovarian cancer
09/25/2008US20080233123 Polypeptide from haemophilus influenzae
09/25/2008US20080233120 Complementarity determining region (CDR); cancer, rheumatoid arthritis; immunology
09/25/2008US20080233119 Modulating death receptor 3 and/or CD30 function; interleukin expression inhibition
09/25/2008US20080233103 Mycobacterial peptide deformylase
09/25/2008US20080233101 RNA-mediated epigenetic regulation of gene transcription
09/25/2008US20080233100 Targeted enzymes
09/25/2008US20080233083 Methods and Compositions for Vaccination of Animals with Prrsv Antigens with Improved Immunogenicity
09/25/2008US20080233046 Antisense agents; RNA interference; gene expression inhibition; hybridomas; hormone replacement therapy
09/25/2008CA2681634A1 Methods and compositions related to riboswitches that control alternative splicing
09/25/2008CA2681323A1 Combined hairpin-antisense compositions and methods for modulating expression
09/25/2008CA2681193A1 Pericycle-specific expression of microrna167 in transgenic plants
09/24/2008EP1972635A1 Compounds and methods for lowering cholesterol levels without inducing hypertriglyceridemia
09/24/2008EP1971864A2 Kit comprising 2,4-dichlorophenoxyacetic acd derivatives and antibodies for highly sensitive detection assays
09/24/2008EP1786916A4 Single-primer nucleic acid amplification methods
09/24/2008EP1599492A4 Receptor deorphanization using tagged molecular libraries
09/24/2008EP1383903B1 Methods for the production of ascorbic acid intermediates in host cells
09/24/2008EP1297179B1 Detection of nucleic acid hybridization by fluorescence polarization
09/24/2008CN101273141A Targeted integration and expression of exogenous nucleic acid sequences
09/24/2008CN101273051A Polymeric oligonucleotide prodrugs
09/24/2008CN101270391A MRNA stem ring structure probe, prepraring method thereof and application of the same in EMSA
09/24/2008CN101270388A Prostate cancer field effect analysis methods and kits
09/24/2008CN101270358A MiRNA sequence and uses thereof
09/24/2008CN101270152A Peptide medicament series for accelerating medulla hematopoiesis cell proliferation
09/24/2008CN101270151A Peptide medicaments for accelerating medulla hematopoiesis cell proliferation
09/24/2008CN101269214A Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
09/24/2008CN100420749C Application of ShRNA pointed at HBV gene in inhibiting hepatitis B virus duplication
09/24/2008CN100420693C Apparatus and method for purification of nucleic acids by phase separation using laser and beads
09/23/2008US7427698 Transgenic cell transformed with polynucleotide to increase drought tolerance
09/23/2008US7427697 Using vector comprising dihydroorotase, translation iniation factor-1a and sugar beet kinase as tool for generating drought, cold and frost resistant crop plants
09/23/2008US7427679 Sugar with heterocyclic base having exocyclic amine group and substituted or unsubstituted triaryl methyl protecting group bound to exocyclic amine group
09/23/2008US7427678 Reacting a derivatized molecule with a support; diels-alder reaction; fluorescein; diene or dienophile
09/23/2008US7427677 Expression of zebrafish bone morphogenetic protein 4
09/23/2008US7427675 Compounds and methods for the characterization of oligonucleotides
09/23/2008US7427673 Labelled nucleotides
09/23/2008US7427672 Artificial nucleic acids of n-o bond crosslinkage type
09/23/2008US7427671 DNA sequence which code human platelet derived growth factor receptor proteins which preferentially binds to dimers of platelet derived growth factors with high receptivity
09/23/2008US7427667 monoclonal; humanized; fragments; labeled
09/23/2008US7427658 Chicken anemia virus mutants and vaccines and uses based on the viral proteins VP1, VP2 and VP3 or sequences of that virus coding therefor
09/23/2008US7427605 Inhibitors of ribonucleotide reductase subunit 2 and uses thereof
09/23/2008US7427604 preventing avian coccidiosis; vaccine; host cell
09/23/2008US7427498 Composition, methods and reagents for the synthesis of a soluble form of human PHEX
09/23/2008US7427488 Purified and isolated platelet calcium channel nucleic acids and polypeptides and therapeutic and screening methods using same
09/23/2008US7427487 for the direct identification of candidate compounds such as receptor agonists, inverse agonists, partial agonist or antagonist for use in graft rejection; inflammatory skin disease; inflammatory bowel disease; allergic inflammation, pulmonary inflammation, inflammatory demyelinating neuropathy
09/23/2008US7427484 Polypeptides, nucleic acids; gene codes; antibiotic, immunosuppressants; identifying a novel secondary metabolite biosynthesis gene cluster in a fungus
09/23/2008US7427483 amplification of the 42-kDa C-terminal region of the MSP1 gene by using the PCR technique in the presence of digoxigenin-11-dUTP and the synthesis of the specific biotin labeled nucleotide probes directed to the 42-kDa C-terminal region of the MSP1 gene
09/23/2008US7427482 screening for nucleotide sequences coding enzymatic polypeptide associated with purine nucleotide biosynthesis for use as cancer diagnositic markers; antiproliferative/antitumor agents
09/23/2008US7427481 Method for identifying a testicular cell of a chicken
09/23/2008US7427477 Method of activating a silicon surface for subsequent patterning of molecules onto said surface
09/23/2008US7427476 Using hypermethylation of T-type calcium channel(CACNA1G) gene sequences as diagnostic indicator of cell proliferative disorders; calcium channel blocker and cancer treatment
09/23/2008US7427475 Using probes specific to grampositive bacteria as tool in diagnosing/prognosing streptococcal infection; colorimetric analysis
09/23/2008US7427472 Methods for the differentiation and identification of medically important endemic fungi
09/23/2008US7427471 Modified “S” antibodies
09/23/2008US7427470 Antisense modulation of helicase-moi expression
09/23/2008US7427405 Immunostimulatory oligonucleotide multimers
09/23/2008CA2226721C Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles
09/23/2008CA2219106C Nucleic acid ligands of tissue target
09/23/2008CA2195209C Use of rna polymerase to improve nucleic acid amplification process
09/23/2008CA2169852C Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
09/23/2008CA2139430C Polypeptides having serotoninergie activity (5ht5a), nucleic acids coding for these polypeptides and uses thereof
09/23/2008CA2118373C Method to reverse the phenotype of transformed cells by the transcription factor irf-1
09/18/2008WO2008112730A1 A method for using lowstrength electric field network (lsen) and immunosuppressive strategies to mediate immune responses
09/18/2008WO2008112404A1 Deployable segmented tlif device
09/18/2008WO2008112311A1 Methods for identifying diabetes and obesity therapeutics
09/18/2008WO2008112162A2 Compositions and methods for treating diseases, disorders or conditions characterized by myelin degeneration, myelin deficiency or loss
09/18/2008WO2008112108A1 In vivo hcv resistance to anti-viral inhibitors
09/18/2008WO2008112015A2 Compositions, kits, and methods for isolating cytoplasmic rna
09/18/2008WO2008112008A2 Sensor proteins and assay methods
09/18/2008WO2008111908A1 Five- and six-membered conformationally locked 2',4'- carbocyclic ribo-thymidines for the treatment of infections and cancer
09/18/2008WO2008111485A1 Compound having structure derived from mononucleoside or mononucleotide, nucleic acid, labeling substance, and method and kit for detection of nucleic acid
09/18/2008WO2008110655A1 Method for the simultaneous detection and quantification of dna from wheat, barley, rye and crosses and mixtures thereof in food, elements required to perform same and use thereof
09/18/2008WO2008110019A1 Clinical sample preparation on a microfluidic platform
09/18/2008WO2008036970A3 Insulin-degrading enzyme mutants and methods of use
09/18/2008WO2007148091B1 Dna molecules and methods
09/18/2008WO2007067719A3 Diagnosing human diseases by detecting dna methylation changes
09/18/2008US20080229450 Using vector transformation to generate plants expressing isopentenyl transferase (IPT) and fatty acid desaturase (FAD) gene sequences for use generating tobacco with enhances storage stability and freeze resistance
09/18/2008US20080229442 Nucleotide sequences and corresponding polypeptides conferring modulated growth rate and biomass in plants grown in saline and oxidative conditions
09/18/2008US20080227969 Nucleic acid adsorbent; methods for adsorbing, removing, dissociating, and recovering nucleic acids using the same; and method for regenerating the same
09/18/2008US20080227968 (S)-3-methoxy-1-(monomethoxytrityl)aminopropane-2-ol; rapidly supply an aminated oligonucleotide with high purity
09/18/2008US20080227967 siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)
09/18/2008US20080227966 Expression vector comprising nucleotide sequences coding glyphosate resistant lyase for use in generation of herbicide resistant plants; controlling weed pest in transgenic crop field
09/18/2008US20080227965 Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
09/18/2008US20080227955 Nematode PAN and ZP Receptor-Like Sequences
09/18/2008US20080227754 Phosphoramidate linkages; retroviral or hepadnaviral therapy; tissue targeted therapy; HIV/aquired immunodeficiency syndrome; antitumor agents; improved bioavailability