Patents
Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892)
10/2008
10/02/2008US20080241124 Nucleotide sequences coding g-protein couple receptor for use in identifying modulators for prevention and treatment of inflammation, sarcoidosis and rheumatoid arthritis
10/02/2008US20080241118 Methods and Compositions for Targeting Proteins Across the Blood Brain Barrier
10/02/2008US20080241110 Targeting of sall4 for the treatment and diagnosis of proliferative disorders associated with myelodysplastic syndrome (MDS)
10/02/2008US20080241108 Bone Morphogenic Protein Binding Peptide
10/02/2008US20080241104 Espfu nucleic acids and proteins and uses thereof
10/02/2008US20080241102 Nucleophile/biodrug cascades
10/02/2008US20080241096 IL-1 family variants
10/02/2008US20080241069 Methods and compositions for treating IgE-mediated diseases
10/02/2008US20080241067 co-culturing cancer cells and host cells for a time sufficient to detect evidence of gene expression in co-culture for simulating the progression from a primary tumor to a metastasis in an in vitro model; anti-EphA2 ( epithelial cell kinase) antibody
10/02/2008CA2681921A1 Peptides with anitfungal activity
10/02/2008CA2680046A1 Methods of diagnosing, classifying and treating endometrial cancer and precancer
10/02/2008CA2676090A1 Genemap of the human genes associated with adhd
10/02/2008CA2653967A1 Lyase enzymes, nucleic acids encoding them and methods for making and using them
10/01/2008EP1975256A1 Modified oligonucleotides for mismatch discrimination
10/01/2008EP1975251A2 Real-time sequence determination
10/01/2008EP1975231A1 Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
10/01/2008EP1975172A2 High affinity TGFß nucleic acid ligands and inhibitors
10/01/2008EP1973946A2 Translocation and mutant ros kinase in human non-small cell lung carcinoma
10/01/2008EP1973945A2 Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis
10/01/2008EP1973927A2 Cationic oligonucleotides, automated methods for preparing same and their uses
10/01/2008EP1973926A2 Methods and compositions for sequencing a nucleic acid
10/01/2008EP1802774A4 Reagents and methods for improving reproducibility and reducing mispriming in pcr amplification
10/01/2008EP1689355A4 Selective inhibitors of nuclear factor-kb activation and uses thereof
10/01/2008EP1633859B1 Cell line and uses thereof
10/01/2008EP1208111B1 Genes encoding insect odorant receptors and uses thereof
10/01/2008EP0766512B1 Replication-competent herpes simplex virus mediates destruction of neoplastic cells
10/01/2008CN101278295A Methods of amplifying and sequencing nucleic acids
10/01/2008CN101275166A Nucleotide primer set and nucleotide probe for detecting genotype of n-acetyltransferase 2 (NAT2)
10/01/2008CN101275163A Restriction enzyme-long catenative sequence semi-synthetic method for gene or nucleic acid sequence
10/01/2008CN101274952A Method for reclaiming DNA from agarose gel
10/01/2008CN100422326C Si RNA capable of controlling foot-and-mouth disease virus copying and infection and its preparing method and use
10/01/2008CN100422320C DNA sequences encoding dystrophin minigenes and methods of use thereof
10/01/2008CN100422319C Method for producing chiral carboxylic acids from nitriles with assistance of nitrilase or microorganisms which contain gene for nitrilase
10/01/2008CN100422316C Neutralizing human anti-IGFR antibody
10/01/2008CN100422210C Recombinant protective protein from streptococcus pneumoniae
10/01/2008CN100422203C Marker primer linked with wheat powdery mildew resistant gene Pm6 and its usage method
10/01/2008CN100422202C Adrenergic receptor SNP for improved milking characteristics
10/01/2008CA2654894A1 Csf3r polypeptides and uses thereof
09/2008
09/30/2008US7429693 Method for the production of plant seed with modified fiber content and modified seed coat
09/30/2008US7429692 Using vector comprising nucleotide sequences coding methyltransferase to generate plants with larger seed size; tissue engineering;
09/30/2008US7429657 DNA molecules encoding enzymes involved in starch synthesis, vectors, bacteria, transgenic plant cells and plants containing these molecules
09/30/2008US7429656 Inhibition of SARS-associated coronavirus (SCoV) infection and replication by RNA interference
09/30/2008US7429655 Method for determining a concentration of target nucleic acid molecules, nucleic acid probes for the method and method for analyzing data obtained by the method
09/30/2008US7429654 Prolongs expression of cold-shock inducible genes under conditions of physiological stress that elicit the cold-shock response in bacteria; nucleotide sequences; genetic engineering
09/30/2008US7429652 Expression vector comprising nucleotide sequences coding non-single-chain antigen-binding units for use in generating immunoglobulins for diagnosing and treating human disease
09/30/2008US7429651 Fluorescent nucleobase conjugates having anionic linkers
09/30/2008US7429650 Methods and compositions in breast cancer diagnosis and therapeutics
09/30/2008US7429649 nucleotide sequences encoding the enzymes 4-coumarate CoA-ligase (4CL), cinnamoyl-CoA reductase (CCR), cinnamyl alcohol dehydrogenase (CAD) of the lignin biosynthetic pathway, from ryegrass (Lolium) and fescue (Festuca); transgenic plant
09/30/2008US7429648 IREN protein, its preparation and use
09/30/2008US7429647 Polypeptides capable of forming antigen binding structures with specificity for the Rhesus D antigens, the DNA encoding them and the process for their preparation and use
09/30/2008US7429645 Humanized anti-lymphotoxin beta receptor antibodies
09/30/2008US7429644 Comprises lymphotoxin beta receptor (LT-BETA-R) immunoglobulin for treatment of tumor disorders
09/30/2008US7429640 PRO6181 polypeptides
09/30/2008US7429569 Compositions and methods for the regulation of homocysteine levels within the body
09/30/2008US7429482 Screening tools for discovery of novel anabolic agents
09/30/2008US7429475 Phytase enzymes, nucleic acid sequences encoding phytase enzymes and vectors and host cells incorporating same
09/30/2008US7429473 Diacylglycerol acyltransferase genes, proteins, and uses thereof
09/30/2008US7429470 for purification of nucleic acids of cells or viruses are provided. The nucleic acid purification apparatus includes: a cell lysis capillary having a sample inlet through which samples and magnetic beads are introduced; a vibrator attached to the capillary and mixing the samples and the magnetic beads
09/30/2008US7429469 producing polyesters resulting from homopolymerization or copolymerization of a 3-hydroxyalkanoic acid(s) and having biodegradability and good physical properties using yeasts as hosts. By constructing at least one enzyme gene involved in polyester synthesis by adding a DNA coding a peroxisome-targeting
09/30/2008US7429468 thermostable mutants of B-type DNA polymerases comprising a Y-GG/A amino acid motif between the N-terminal 3'-5'-exonuclease domain and the C-terminal polymerase domain whereas the tyrosine of the Y-GG/A amino acid motif is mutated and whereas these mutant DNA polymerases are suitable for PCR.
09/30/2008US7429456 Identification of a JAK2 mutation in Polycythemia Vera
09/30/2008US7429455 analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes.
09/30/2008US7429452 Methods for diagnosis and therapy of pancreatic cancer and composition useful therein
09/30/2008US7429451 Nucleic acids isolated from stage 4 neuroblastoma
09/25/2008WO2008116223A1 Preq1 riboswitches and methods and compositions for use of and with preq1 riboswitches
09/25/2008WO2008115525A2 Metal-binding therapeutic peptides
09/25/2008WO2008115487A1 Methods of affecting plant growth with microrna
09/25/2008WO2008115387A2 Screening, diagnosing, treating and prognosis of pathophysiologic states by rna regulation
09/25/2008WO2008114672A1 Cancer-specific biomarker
09/25/2008WO2008081066A8 Method for detecting and identifying peronospora arborescens
09/25/2008WO2008073201A3 Compositions and methods for identifying agents that alter expression of survivin
09/25/2008WO2008070477A3 Polymeric short interfering rna conjugates
09/25/2008WO2008066776A3 Methods for treating hypercholesterolemia
09/25/2008WO2008030616A3 Monitoring cancer stem cells
09/25/2008WO2007081534A3 Method of producing catalytically active bace2 enzymes
09/25/2008WO2007040546A3 Production of recombinant protein pap 31 for the diagnosis and prevention of bartonella bacilliformis infection
09/25/2008US20080235826 useful in the production of dwarf plants; type 5 serine/threonine protein phosphatase activity; production of plants sensitive to light signal transduction
09/25/2008US20080235816 Multiple inducible gene regulation system
09/25/2008US20080234474 Methods for the separation of biological molecules using sulfolane
09/25/2008US20080234473 Oligonucleotide probe for use as diagnostic indicator in dection of urogenital infections
09/25/2008US20080234465 Expression in filamentous fungi of protease inhibitors and variants thereof
09/25/2008US20080234219 TGF- beta binding proteins which can be utilized to increase bone mineralization, and thus may be utilized in treating osteopenia, osteoporosis and bone fractures
09/25/2008US20080234218 Sirna For Inhibiting Il-6 Expression and Composition Containing Them
09/25/2008US20080234217 Double stranded nucleotide sequences for use as tools in tissue targeted gene expression inhibition and treatment of cancer, vascular, neuronal and endocrine diseases
09/25/2008US20080234216 TGF-beta type receptor cDNAs encoded products and uses therefor
09/25/2008US20080234215 DNA composition and uses thereof
09/25/2008US20080234213 Oncogenic regulatory RNAs for diagnostics and therapeutics
09/25/2008US20080234212 siRNA molecules which target the transcription factor STAT6 and repress the expression of STAT6 mRNA, STAT6 protein and STAT6 function in lung cells
09/25/2008US20080234191 Depleting complement; treatment of diseases such as reperfusion injury, autoimmune diseases, and other diseases of increased complement activation; increasing the efficiency and/or effectiveness of gene therapy; may be chemically linked to an antibody with an affinity for a specific tissue
09/25/2008US20080234187 In particular amidated, acetylated, phosphorylated and/or glycosylated derivatives; diagnostic agents including a nucleic acid or messenger RNA coding for the cytokine; isolated from human hemofiltrate
09/25/2008US20080233645 Methods and Compositions of Ig20 and Denn-Sv Splice Variants
09/25/2008US20080233644 Chimeric Transcription Factor Decoy Oligonucleotides
09/25/2008US20080233639 Fusion protein delivery system and uses thereof
09/25/2008US20080233638 Nucleotide sequences coding regulatory proteins comprising death domains for identifying modulators of nuclear factor kappa beta activity and treatments for cell proliferative and neurodegenerative diseases; gene expression inhibition
09/25/2008US20080233618 Isolated, purified genetic engineered DNA; culturing a host cell to produce polyketide
09/25/2008US20080233613 Polypeptides having beta-glucosidase activity and polynucleotides encoding same
09/25/2008US20080233611 pairs of orthogonal-tRNAs (O-tRNAs) and orthogonal aminoacyl-tRNA synthetases (O RSs) that do not interact with the host cell translation machinery
09/25/2008US20080233598 Active and/or passive immunization; accurate early stage, localized tumor detection
09/25/2008US20080233589 If a molecular interaction occurs, then the heterologous polypeptide fragments are able to associate and produce a detectable signal; allows for real time enhanced imaging of biomolecule interactions both in vitro and in vivo
09/25/2008US20080233588 Using RNA probes to quantify and detect preferential nucleotide sequences in sample; bioassay; bioluminescent signalling system comprises luciferase and luciferin