| Patents for C07H 21 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids (89,892) |
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| 07/31/2008 | US20080182835 Cobalt attached/coordinated to 6 same or different ligands including a N-based ligand donor atom that is ammonia, primary amine or secondary amine, or salt; does not have free cobalt(III) coordination sites and does not hydrolyze oligonucleotides; complex may be bound to an oligonucleotide |
| 07/31/2008 | US20080182813 UNIVERSAL TARGET SEQUENCES FOR siRNA GENE SILENCING |
| 07/31/2008 | US20080182810 Antisense modulation of acyl coa cholesterol acyltransferase-2 expression |
| 07/31/2008 | US20080182809 Oligonucleotide sequences which bind biomolecules such as peptides, hydrophobic molecules and extracellular proteins for diagnosing and treating cardiovascular disorders in mammals |
| 07/31/2008 | US20080182808 Capable of inducing breakdown of mrna enzymes that break down connective tissue; particularly suited for treating degenerative skin disorders; pharmaceutical and cosmetic compositions for topical application and which contain the oligoribonucleotides |
| 07/31/2008 | US20080182807 gene therapy against tumors and cancer; expression vector includes insert into tumor an effective amount of polynucleotides encoding a functionally active p53, express p53 to first DNA damaging agent, contact tumor cell with first DNA damaging agent, and kill tumor cell |
| 07/31/2008 | US20080182793 Polypeptide comprising oxidized lipid and/or carbohydrate binding activity for use as tool in diagnosis, prevention and treatment of thrombosis, atherosclerosis, inflammatory and bone disorders |
| 07/31/2008 | US20080182790 Nucleic acid encoding protein which has autoinducer inactivation activity; increase disease resistance in plants and animals; capable of efficient inactivation of N-acyl homoserine lactone autoinducers |
| 07/31/2008 | US20080182777 Regulation of cell migration and adhesion |
| 07/31/2008 | US20080182760 Oligonucleotide linkers comprising a variable cohesive portion and method for the preparation of polynucleotide libraries by using said linkers |
| 07/31/2008 | US20080182332 Optimized non-canonical zinc finger proteins |
| 07/31/2008 | US20080182321 Hybrid mushroom strain J9277 and its descendants |
| 07/31/2008 | US20080182315 specified domain capable of independently functioning as a potential sensor and another domain exhibiting a phosphatise activity; capable of converting electrical signals to chemical signals |
| 07/31/2008 | US20080182314 Neuronal serine threonine protein kinase |
| 07/31/2008 | US20080182313 Polypeptide of 250-419 contiguous amino acids of SEQ ID NO:1, where tyrosine 216 is phosphorylated and the polypeptide will crystallize; biological activity consisting of binding a GSK3 inhibitor and kinase activity; antidiabetic agents; Alzeimer's disease; antiinflammation agents; biological screening |
| 07/31/2008 | US20080182311 Novel trehalose synthase from Picrophilus torridus and methods of use thereof |
| 07/31/2008 | US20080182299 Polynucleotide variants of brain natriuretic peptides used as diagnostic markers for cardiovascular diseases including myocardial infarct, acute coronary syndrome, angina pectoris (stable and unstable), cardiomyopathy, myocarditis, congestive heart failure; kits; monitoring disease progression , relapse |
| 07/31/2008 | US20080182296 Pcr-directed gene synthesis from large number of overlapping oligodeoxyribonucleotides |
| 07/31/2008 | US20080182294 Recombinant clostridial neurotoxins (botulinum) having functional binding, translocation, and therapeutic domains; also an amino acid sequence susceptible to specific cleavage by proteases in vitro following expression as a single chain; inserts; therapeutic agents, transporter molecules; drug delivery |
| 07/31/2008 | US20080182275 Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| 07/31/2008 | US20080182268 Schizophrenia associated genes, proteins and biallelic markers |
| 07/31/2008 | US20080182237 MiRNAs; diagnosis, prognosis, and treatments; drug screening; linear amplification and labeling for hybridization techniques like Luminex and Microarray analysis; gene expression inhibition |
| 07/31/2008 | US20080182236 Within human chromosome 7p15-p14; GPRA polypeptides, nucleic acids, host cells, primers and probes; transgenic animal models; anticarcinogenic agents; chronic obstructive pulmonary disorder; diagnosis; analyzing allelic variation in the locus and GPRA gene |
| 07/31/2008 | US20080181925 Compositions and Methods for Enzymatic Detachment of Bacterial and Fungal Biofilms |
| 07/31/2008 | US20080181909 Chimeric immunomodulatory compounds and methods of using the same |
| 07/31/2008 | US20080181908 Genes and proteins, and their use |
| 07/31/2008 | US20080181907 Methods and kits for diagnosing and treating b-cell chronic lymphocytic leukemia |
| 07/31/2008 | US20080181906 For inducing neutralizing antibodies against HIV; hairpin motif; HIV gp120; hydrogen bonding |
| 07/31/2008 | US20080181894 Tumor/cancer antigens; solid phase synthesis; drug screening |
| 07/31/2008 | US20080181892 Binding Domain Fusion Protein |
| 07/31/2008 | US20080181886 Polypeptides That Bind Baff And/Or April |
| 07/31/2008 | US20080181885 202P5A5 gene or fragment or its encoded protein, or variants , or a fragment, used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 202P5A5 be used in active or passive immunization; gene therapy, immunotherapy; anticarcinogenic agent biodrug for pancreatic cancer |
| 07/31/2008 | DE102005011003B4 Verfahren und Mittel zur differentiellen Diagnose von Schilddrüsentumoren Method and means for the differential diagnosis of thyroid tumors |
| 07/31/2008 | CA2675290A1 Dna methylation changes associated with major psychosis |
| 07/31/2008 | CA2657626A1 Viral inhibitory nucleotide sequences and vaccines |
| 07/30/2008 | EP1950288A1 Endoglucanase from Thermotoga |
| 07/30/2008 | EP1950226A2 Receptors for human interleukin-12 |
| 07/30/2008 | EP1949913A1 Immunostimulatory combination for the prophylactics and treatment of hepatitis c |
| 07/30/2008 | EP1949103A2 Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| 07/30/2008 | EP1948832A2 Detection of nucleic acids by target-specific hybrid capture method |
| 07/30/2008 | EP1948827A2 C-kit oncogene mutations in melanoma |
| 07/30/2008 | EP1948796A1 Process for the preparation of nucleic acid duplexes |
| 07/30/2008 | EP1948674A1 Modified sirna molecules and uses thereof |
| 07/30/2008 | EP1948247A2 Compositions for coordinated vegf and pdgf expression, and methods of use |
| 07/30/2008 | EP1948244A2 Pharmaceutical composition and method for regulating abnormal cellular proliferation |
| 07/30/2008 | EP1828422A4 Detection using primers to repetitive dna and transcription-based amplification thereby |
| 07/30/2008 | EP1699923B1 Oligonucleotide and the use thereof for modulating an isoform c beta-1 protein-kinase in the form of a skin depigmentation agent |
| 07/30/2008 | EP1480993B1 Desaturase genes, enzymes encoded thereby, and uses thereof |
| 07/30/2008 | EP1401259B1 Delta-4 desaturase genes and uses thereof |
| 07/30/2008 | EP1392868B1 Method for the synthesis of dna sequences using photo-labile linkers |
| 07/30/2008 | EP0994728B1 Recombinant antibodies specific for beta-amyloid ends, dna encoding and methods of use thereof |
| 07/30/2008 | EP0961825B1 Mutant penicillin g acylases |
| 07/30/2008 | CN101233235A Methods for synthesis of encoded libraries |
| 07/30/2008 | CN101233233A Method for separating and purifying RNA |
| 07/30/2008 | CN101233144A 稳定的nad/nadh衍生物 Stable nad / nadh derivatives |
| 07/30/2008 | CN101230398A Method for preparing three-dimensional gel micro array chip without excitant |
| 07/30/2008 | CN101230394A Multiplex amplification of short tandem repeat loci |
| 07/30/2008 | CN101230380A Characteristic sequences and method for discriminating pivot-end cordyceps sinensis |
| 07/30/2008 | CN101230357A Plant expression vector for improving aluminum-tolerance of plant |
| 07/30/2008 | CN100406554C Colibacillus containing human source guide suppository dissolving antibody gene and its secretion producg |
| 07/30/2008 | CN100406466C Nucleic acid hydrolysis cutting agent based on cucurbituril |
| 07/29/2008 | US7405346 Gene capable of imparting salt stress resistance |
| 07/29/2008 | US7405345 cultivating a transgenic plant containing a nucleotide sequences coding polypeptide, proteins and other products of interest; controlling expression of nucleic acid sequences; product is produced in seed of the plant; increase the oleic acid content of rapeseed oil |
| 07/29/2008 | US7405292 Small, interfering RNA (siRNA) molecules which inhibit expression of HALP (HIV-Associated Life Preserver) protein cloned into a plasmid or retroviral vector for introduction into host cells; screening HIV-modulating componds which prevent apoptosis resistance of infected cell; gene therapy |
| 07/29/2008 | US7405291 Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| 07/29/2008 | US7405290 A gene (designated 161P2F10B) and its encoded protein which exhibits tissue specific expression in normal adult tissue and is aberrantly expressed in the cancers; medical diagnostis;, prognosis, prophylactis and/or gene therapy; tissue-target therapy; used to elicit a humoral or cellular immune response |
| 07/29/2008 | US7405289 Polynucleotide encoding polypeptide comprising proline/glutamine rich domain, an RFX DNA binding domain, an RFX B domain, an RFX C domain, a dimerization domain and a serine/threonine domain; drug screening ; gene therapy; promote differentiations into functioning beta-cells(insulin); diabetes diagnosis |
| 07/29/2008 | US7405288 V-like domain binding molecules and polynucleotides encoding therefor |
| 07/29/2008 | US7405287 Method of treating a cancer |
| 07/29/2008 | US7405286 An isolated polynucleotide encoding the STAR (a striated muscle activated of Rho signaling) polypeptide comprising SEQ ID NO:4; expression inhibition useful in therapy/prevention of cardiovascular disorders,e.g., myocardial infraction, heart failure, cardiac hypertrophy, dilated cardiomyopathy |
| 07/29/2008 | US7405285 Immunostimulatory oligonucleotide multimers |
| 07/29/2008 | US7405284 Reducing cellular dysfunction caused by mitochondrial gene mutations |
| 07/29/2008 | US7405283 Using defects in base excision repair and glycosylase activity as diagnostic indicators of cell proliferative disorders of bowels |
| 07/29/2008 | US7405281 Fluorescent nucleotide analogs and uses therefor |
| 07/29/2008 | US7405275 Nucleic acid and vectors encodes antibodies ; antigen binding fragments |
| 07/29/2008 | US7405269 Identification and isolation of novel DNA and recombinant production of novel polypeptides |
| 07/29/2008 | US7405205 Antitumor antisense sequences directed against R1 and R2 components of ribonucleotide reductase |
| 07/29/2008 | US7405074 Glyphosate-N-acetyltransferase (GAT) genes |
| 07/29/2008 | US7405066 Genome of given DNA sequence; capable of lysing Propionibacterium for treatment of acne |
| 07/29/2008 | US7405064 Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from Comamonas testosteroni 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids |
| 07/29/2008 | US7405061 for drug screening/diagnosis and/or treatment of a variety of human diseases and cancers; immunotherapy; genetic engineering |
| 07/29/2008 | US7405059 Modified Shine-Dalgarno sequences and methods of uses thereof |
| 07/29/2008 | US7405050 Contacting vibrio cells comprising inactivated qrr gene with test compound and determining if it's a regulator |
| 07/29/2008 | US7405044 Multiplex PCR for simultaneous quantitation of human nuclear, mitochondrial, and male Y-chromosome DNA |
| 07/29/2008 | US7405043 Responsiveness to therapy for liver disorders |
| 07/29/2008 | US7405042 Method of extracting nucleic acid or protein using dendrimers and dendrimer-compositional substances |
| 07/29/2008 | US7405040 Preamplification of Dna; fluorescence labels; polymerase chain reaction |
| 07/29/2008 | US7404969 One or more short interfering RNA, 3-dimethylamino-2-(cholest-5-en-3-beta-oxybutan-4-oxy)-1-(cis,cis-9,12-octadecadienoxy) propane, distearoyl phosphatidylcholine, cholesterol, and 1-[8'-(1,2-Dimyristoyl-3-propanoxy)-carboxamido-3',6'-dioxaoctanyl]carbamoyl-omega-methyl-polyethylene glycol; transfection |
| 07/29/2008 | US7404958 Administering polypeptide which elicits an immune response |
| 07/29/2008 | US7404956 Immunoglobulin chimeric monomer-dimer hybrids |
| 07/29/2008 | US7404950 Induced activation in dendritic cell |
| 07/29/2008 | CA2413670C Human brain and testis-specific immunoglobulin superfamily (bt-igsf) cdna for diagnosis of aplasia of corpus callosum and aspermatogenesis |
| 07/29/2008 | CA2296144C Oligonucleotide primers for efficient detection of hepatitis c virus (hcv) and methods of use thereof |
| 07/29/2008 | CA2268771C Polymorphisms and new genes in the region of the human hemochromatosis gene |
| 07/24/2008 | WO2008088583A2 Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
| 07/24/2008 | WO2008088548A2 Disintegrin variants and pharmaceutical uses thereof |
| 07/24/2008 | WO2008033403A3 Agents and methods to elicit anti-tumor immune response |
| 07/24/2008 | WO2008019006A3 Serum dna methylation screening for cancer |
| 07/24/2008 | WO2008008476A3 Transducible delivery of nucleic acids by reversible phosphotriester charge neutralization protecting groups |
| 07/24/2008 | WO2007136989A3 Compounds and methods for modulating expression of dgat2 |