| Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960) |
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| 03/20/2008 | US20080070950 Amorphous rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2- methylpropionic acid and its pharmaceutical compositions |
| 03/20/2008 | US20080070907 Substituted chiral fused [1,2] imidazo [4,5-C] ring compounds and methods |
| 03/20/2008 | CA2660987A1 Benzoxazoles and oxazolopyridines being useful as janus kinases inhibitors |
| 03/19/2008 | EP1900742A1 Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof |
| 03/19/2008 | EP1900741A1 New process for the production of oxabispidines |
| 03/19/2008 | EP1900729A1 Benzoxazoles and oxazolopyridines being useful as Janus kinases inhibitors |
| 03/19/2008 | EP1778696B1 (1,10b-dihydro-2-(aminocarbonyl-phenyl)-5h-pyrazolo[1,5- c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as hiv viral replication inhibitors |
| 03/19/2008 | EP1490344B1 Anxiolytic agents with reduced sedative and ataxic side effects |
| 03/19/2008 | EP1399450B1 Benzoxazepine derivatives and their use as ampa receptor stimulators |
| 03/19/2008 | CN101146889A Luminous compound containing lanthanide ion |
| 03/19/2008 | CN101146811A Hiv整合酶抑制剂 Hiv integrase inhibitors |
| 03/19/2008 | CN101146807A Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-C][1,5]naphthyridin-4-amine |
| 03/19/2008 | CN101143867A Antidepressant indolealkyl derivatves of heterocyclefused benzodioxan methylamines |
| 03/18/2008 | US7345055 2,7-dimethylimidazo[1,2- alpha ]pyridin-3-ylmethyl)-dimethylamine; nitric oxide synthase inhibitor; neurodegenerative diseases and antiinflammatory, antitumor agent; multiple sclerosis, Parkinson's, Alzheimer's or Huntington's disease, cerebral ischemia, diabetes, meningitis, angiogenesis, |
| 03/18/2008 | US7345053 Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use |
| 03/18/2008 | US7345038 Pyridyloxymethyl and benzisoxazole azabicyclic derivatives |
| 03/18/2008 | US7345036 (Pyrido/thieno)—[f]—oxazepine-5-one derivatives |
| 03/18/2008 | CA2277893C 4-(3-heterocyclyl-1-benzoyl)pyrazoles and their use as herbicides |
| 03/18/2008 | CA2219659C Rapamycin derivatives |
| 03/13/2008 | WO2008028934A1 Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof |
| 03/13/2008 | WO2008008480A3 Nitroheteroaryl-containing rifamycin derivatives |
| 03/13/2008 | WO2007148185A3 Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors |
| 03/13/2008 | WO2007136302A8 Active substances, pharmaceutical composition and a method for the production and use thereof |
| 03/13/2008 | CA2662776A1 Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease |
| 03/13/2008 | CA2662308A1 Conjugates of disorazoles and their derivatives with cell-binding molecules, novel disorazole derivatives, processes of manufacturing and uses thereof |
| 03/12/2008 | EP1896488A2 Process for purifying tacrolimus |
| 03/12/2008 | EP1896487A1 Process for the preparation of sulfonic acid salts of oxabispidines |
| 03/12/2008 | EP1896486A1 Process for the preparation of 3,7-dihydroxy-1,5-diazacyclooctanes |
| 03/12/2008 | EP1896485A1 Azolopyridine-2-on derivatives as lipase and phospholipase inhibitors |
| 03/12/2008 | EP1896477A1 Aspartyl protease inhibitors |
| 03/12/2008 | CN101139351A Perfluoro alkyl substituted perylene bis diimines and derivative and preparation method thereof |
| 03/12/2008 | CN100374438C Pre-organized tricyclic integrase inhibitor compounds |
| 03/12/2008 | CN100374158C application of agent for lowering the cell ATP level in preparing medicine |
| 03/11/2008 | US7342118 Imidazole compounds for the treatment of neurodegenerative disorders |
| 03/11/2008 | US7342027 1-phenylpiperidin-3-one derivatives and processes for the preparation thereof |
| 03/11/2008 | US7342025 Substituted C-imidazo[1,2-a]pyridin-3-yl-methylamines |
| 03/11/2008 | US7342011 Rifamycin analogs and uses thereof |
| 03/06/2008 | WO2008027990A1 Therapeutic methods using wrn binding molecules |
| 03/06/2008 | WO2008026172A1 Spiro antibiotic derivatives |
| 03/06/2008 | WO2008026046A1 Morpholine d3 dopamine antagonists |
| 03/06/2008 | WO2008025512A1 Pyrrolo isoquinolines as kinase inhibitors |
| 03/06/2008 | WO2008011110A3 Di-amino-substituted heterocyclic compounds and methods of use |
| 03/06/2008 | WO2008008432A3 Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods |
| 03/06/2008 | WO2008006884A3 Mtki quinazoline derivatives |
| 03/06/2008 | US20080058514 ceramide-like inhibitors; novel intermediates formed during the synthesis; Glycosphingolipids |
| 03/06/2008 | US20080058319 Fused ring heterocycles as potassium channel modulators |
| 03/06/2008 | CA2664433A1 Therapeutic methods using wrn binding molecules |
| 03/06/2008 | CA2660980A1 Pyrrolo isoquinolines as kinase inhibitors |
| 03/06/2008 | CA2659493A1 Spiro antibiotic derivatives |
| 03/05/2008 | EP1894920A1 Pharmaceutical composition comprising azarhodacyanine compound as active ingredient |
| 03/05/2008 | EP1893620A2 Substituted spiro compounds and their use for producing pain-relief drugs |
| 03/05/2008 | EP1893619A1 New oxabispidine compounds for the treatment of cardiac arrhytmias |
| 03/05/2008 | EP1893599A1 Compounds for the treatment of multi-drug resistant bacterial infections |
| 03/05/2008 | EP1383733B1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds |
| 03/05/2008 | CN101137660A Benzothiazole, thiazolopyridine, benzooxazole and oxazolopyridine derivatives as antidiabetic compounds |
| 03/05/2008 | CN101137659A Oxepane isomer of 42-o-(2-hydroxy)ethyl-rapamycin |
| 03/05/2008 | CN100372848C Spiroazacyclic compounds as monoamine receptor modulators |
| 03/05/2008 | CN100372841C Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity |
| 03/04/2008 | US7339003 Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals |
| 03/04/2008 | US7338964 2-(2-oxa-3-azabicyclo[2.2.2]oct-5-en-3-yl)-6-amino-9-methyl-1-deazapurine; antiinflammatory, neuroleptic agent, antiallergens, neuroprotectant and antidepressant, cognition activator; improved bioavailability, without a ribose moiety; prodrugs with primary or secondary amino or hydroxy groups |
| 02/28/2008 | WO2008009700A8 Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones |
| 02/28/2008 | US20080051394 6H-Oxazolo[4,5 e]indole derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
| 02/28/2008 | US20080051390 Such as 8-[3-(2-Fluoropyridin-3-yl)phenyl]-8-pyridin-4-yl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine; amyloid disorders, Alzheimer's disease, Down's syndrome |
| 02/27/2008 | EP1892239A1 Inhibitors of cytosolic phospholipase A2 |
| 02/27/2008 | EP1532155B1 C6- AND C9-SUBSTITUTED CHROMENO[4,3-c]ISOXAZOLINE DERIVATIVES AND THEIR USE AS ANTI-DEPRESSANTS |
| 02/27/2008 | EP1392870B1 Screening for enzyme inhibitors |
| 02/27/2008 | CN101133066A Recovery of CCI-779 from mother liquors |
| 02/27/2008 | CN101133065A Purification of rapamycin |
| 02/27/2008 | CN101133064A Substituted oxa-diaza-spiro-[5.5]-undecanone derivatives and their use as neurokinin antagonists |
| 02/26/2008 | US7335667 Use as anticancer agents, immunosuppressants for transplants or autoimmune diseases, or against immune reactions (e.g. contact dermatitis or diarrhea) caused by other drugs; e.g. 3-(3-[methyl(1H-pyrrolo[2,3-b]pyridin-4-yl)amino]piperidin-1-yl)-3-oxopropanenitrile |
| 02/21/2008 | WO2008020607A1 Phthalide derivative and salt thereof |
| 02/21/2008 | WO2007136746A3 Macrocyclic compounds and their uses as stearoyl-coa desaturase |
| 02/21/2008 | WO2007075809A3 Oxazoloisoquinoline derivatives as thrombin receptor antagonists |
| 02/21/2008 | US20080045521 Phenylalanine derivatives |
| 02/21/2008 | US20080045520 Substituted Pyrrolidine Derivative |
| 02/21/2008 | US20080045498 Polycyclic viral inhibitors |
| 02/21/2008 | CA2660441A1 Imidazole amines as inhibitors of .beta.-secretase |
| 02/20/2008 | EP1888597A2 Antibacterial agents |
| 02/20/2008 | EP1888596A1 Substituted spiro compounds and their use for producing pain-relief medicaments |
| 02/20/2008 | EP1888595A2 Spiro-oxindole compounds and their uses as therapeutic agents |
| 02/20/2008 | EP1888530A2 Quinoline derivatives as neurokinin receptor antagonists |
| 02/20/2008 | CN100369920C Crystallization and purification of macrolides |
| 02/20/2008 | CN100369919C Tricyclic protein kinase inhibitors |
| 02/19/2008 | US7332604 a histamine H3 antagonist; obesity, metabolic syndrome, diabetes, hepatic lipidosis or nonalcoholic fatty liver disease |
| 02/19/2008 | US7332601 CCI-779 derivatives and methods of making same |
| 02/19/2008 | US7332500 Heterocyclic antiviral compounds |
| 02/19/2008 | US7332498 N-(3-amino-propyl)-N-[1-(3-benzyl-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl)-2-methyl-propyl]-4-methyl-benzamide; kinesin spindle protein inhibitor; cell division, mitosis phase arrest; antiproliferative and antiinflammation agent, hyperplasias, restenosis, cardiac hypertrophy, autoimmune disorders |
| 02/19/2008 | CA2226582C Non-allosteric gabaa agonists for treating sleep disorders |
| 02/14/2008 | WO2008019124A1 Heteroaryl compounds useful as inhibitors of e1 activating enzymes |
| 02/14/2008 | WO2008017688A1 2-carboxy thiophene derivatives as anti-viral agents |
| 02/14/2008 | WO2007136302A3 Active substances, pharmaceutical composition and a method for the production and use thereof |
| 02/14/2008 | WO2007117381A3 2 -aminopyridine analogs as glucokinase activators |
| 02/14/2008 | US20080039630 Cyanine compounds and their application as quenching compounds |
| 02/14/2008 | US20080039486 Rapamycin analogues; diabetes, acute or chronic rejection of an organ or tissue transplant, asthma, tumours, psoriasis, eczema, rheumatoid arthritis, fibrosis, and allergies |
| 02/14/2008 | US20080039469 3-Benzyl-3a-cyclobutyl-7-methoxymethyl-2-oxo-octahydro-oxazolo[4,5-c]pyridin-5-ium; useful as agents for stimulating the cognitive functions of the brain |
| 02/14/2008 | US20080039449 [1,4]benzodiazepine derivatives, used for treating osteoarthritis, pancreatitis, glomerulonephritis, rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, psoriasis, graft vs host disease, leukemia, septic shock, multiple sclerosis, and inflammatory bowel disease |
| 02/14/2008 | US20080039439 Alpha2C adrenoreceptor agonists |
| 02/14/2008 | US20080039327 3-heterocyclyl-substituted benzoyl derivatives |
| 02/14/2008 | US20080035243 Covalent modification of metal surfaces |
| 02/14/2008 | CA2659894A1 Heteroaryl compounds useful as inhibitors of e1 activating enzymes |