| Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960) |
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| 04/29/2008 | US7365065 Antigonadotrophins; Breast and prostate cancer, endometriosis and benign prostate hyperplasia; regulation of fertility; in-vitro fertilisation; oral administration; inexpensive; 3-Amino-4-chloro-N-[4-chloro-5-(2,3-dihydro-benzo[1,4]oxazine-4-carbonyl)-thiophen-3-ylmethyl]-N-methyl-benzenesulfonamide |
| 04/24/2008 | WO2008049123A2 2,4-pyrimidinediamine derivatives as inhibitors of jak kinases for the treatment of autoimmune diseases |
| 04/24/2008 | WO2008048611A1 Process for the synthesis of individual isomers of mono-peg cci-779 |
| 04/24/2008 | WO2008046232A1 Aziridine aldehydes, aziridine-conjugated amino derivatives, aziridine-conjugated biomolecules and processes for their preparation |
| 04/24/2008 | US20080097095 Preparation of levofloxacin hemihydrate free of levofloxacin monohydrate by reacting (S)-(-) 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4] benzoxazine-6-carboxylic acid with N-methyl piperazine to yield crude levofloxacin which is suspended in isopropanol, adding water, precipitating |
| 04/24/2008 | US20080097093 Preparing an individual isomer of mono-pegylated rapamycin 42 ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779) by reacting an isomer of rapamycin with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid; use in treating nerve system cancer, leukemia, breast cancer, prostate cancer |
| 04/24/2008 | US20080096914 cell-cycle dependent apoptosis inducing activity; targeted cancer therapy; 3-Cyano-2-(3-pyridin-3-yl-propanoylamino)-4,7-dihydro-5H-thieno[2,3-c]pyridine-6-carboxylic acid ethyl ester |
| 04/24/2008 | US20080096903 inhibitors of disease-related target, Heat Shock Protein 90 (HSP90); antiproliferative; 2-chloro-5'-sulfamoyladenosine analogs; derivatives of adenine and other purines; Sulfamic Acid 2-[6-amino-2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-purin-9-yl]-ethyl ester |
| 04/24/2008 | US20080096864 Partially imatinib-resistant tumors; synergistic; combined packaging; oral administration |
| 04/24/2008 | US20080096862 Lactam compounds and pharmaceutical use thereof |
| 04/24/2008 | US20080096830 9a-aza-9a-Homoerythromycin derivatives with a dibenzo[e,h]azulene subunit; asthma, adult respiratory distress syndrome; gastrointestinal, respiratory system, autoimmune, genetic, skin, rheumatic, or smooth muscular disorders; inhibitors of tumor necrosis factor, interleukins, leukotrienes, lipoxygenase |
| 04/24/2008 | US20080096048 Thermally reversible; absorption ratio greater than 2.3 |
| 04/24/2008 | CA2702605A1 Unprotected amino aldehydes and applications for same |
| 04/24/2008 | CA2673125A1 Compositions and methods for inhibition of the jak pathway |
| 04/23/2008 | EP1912989A2 Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators |
| 04/23/2008 | EP1054875B1 Insecticidal dihydro-oxadiazines, -thiadiazines and -triazines |
| 04/23/2008 | CN100383145C 4-biphenyl-substituted 4-substituted pyrazolidin-3,5-diones pesticide agent and/or microbicide and/or herbicide |
| 04/22/2008 | US7361670 Amide derivatives as NMDA receptor antagonists |
| 04/22/2008 | US7361647 hydroquinone derivatives of the Geldanamycin family; heat shock protein (chaperone) Hsp90 antagonist; improved solubility and air stability; antiproliferative and anticarcinogenic agents |
| 04/17/2008 | WO2008046046A1 Tricyclic spiro-oxindole derivatives and their uses as therapeutic agents |
| 04/17/2008 | WO2008045377A2 High-purity large-scale preparation of stannsoporfin |
| 04/17/2008 | WO2008044022A1 Fused thiazole derivatives as kinase inhibitors |
| 04/17/2008 | US20080091263 Apparatus and Methods for Preventing or Treating Failure of Hemodialysis Vascular Access and Other Vascular Grafts |
| 04/17/2008 | US20080090867 Azole derivatives in the form of lipase and phospholipase inhibitors |
| 04/17/2008 | US20080090815 Anticoagulates for treating cardiovascular disorders, such as myocardial infarct, angina pectoris, restenoses after angioplasty, bypass, stroke; treatment of atherosclerosis, arthritis, Alzheimer's disease or cancer |
| 04/17/2008 | CA2666136A1 Tricyclic spiro-oxindole derivatives and their uses as therapeutic agents |
| 04/17/2008 | CA2665075A1 High-purity large-scale preparation of stannsoporfin |
| 04/16/2008 | EP1911760A1 Xanthine oxidase inhibitor |
| 04/16/2008 | EP1911753A1 Spiro-cyclic compound |
| 04/16/2008 | EP1910382A1 Purification of tacrolimus on supports of vegetable origin |
| 04/16/2008 | EP1910381A2 Substituted 1-oxa-3,8-diazaspiro[4.5]-decan-2-on- compounds and the use thereof for producing drugs |
| 04/16/2008 | EP1910380A1 Oxazolopyridine derivatives as sirtuin modulators |
| 04/16/2008 | EP1910379A2 Caspase inhibitor prodrugs |
| 04/16/2008 | EP1910358A2 Heterocyclic janus kinase 3 inhibitors |
| 04/16/2008 | EP1910350A1 2 -heterocyclyloxybenzoyl amino heterocyclyl compounds as modulators of glucokinase for the treatment of type 2 diabetes |
| 04/16/2008 | EP1910319A1 Use of tetrahydrobenzoxazines as stabilisers |
| 04/16/2008 | CN100381566C Recombinant methods and materials for producing epothilone and eopthilone derivatives |
| 04/15/2008 | USRE40245 Gyrase inhibitors and uses thereof |
| 04/15/2008 | US7358367 Present invention relates to the new 3-decladinosyl derivatives of 9-deoxo-9a-aza9a-homoerythromycin a 9a, 11-cyclic carbamates |
| 04/15/2008 | US7358364 Substituted carboxylic acids |
| 04/15/2008 | US7358246 5-(4,4-dimethyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbothioamide; contraceptive, menopause; reduces risk of uterine cancers coused by treating with estrogen receptor (ER) agonists |
| 04/15/2008 | US7358245 Administering a therapeutically effective amount of a compound which is a cannabinoid receptor agonist, a pharmaceutically acceptable salt of the compound, an isomer of the compound, or a pharmaceutically acceptable salt of the isomer |
| 04/10/2008 | WO2008002959A3 Hiv integrase inhibitors |
| 04/10/2008 | US20080085925 Sulfonyltetrahydro-3H-benzo(e)indole-8-amine compounds as 5-hydroxytryptamine-6 ligands |
| 04/09/2008 | EP1907399A1 5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as cxc-chemokine receptor ligands |
| 04/09/2008 | CN101160315A Cytoskeletal active compounds, composition and use |
| 04/09/2008 | CN101160307A Benzoxazole carboxamides for treating cinv and ibs-d |
| 04/09/2008 | CN101160293A Azole derivatives in the form of lipase and phospholipase inhibitors |
| 04/09/2008 | CN101157619A Process for producing intermediate for benzoxazine derivative |
| 04/09/2008 | CN100379743C New oxabispidine compound useful in treatment of cardiac arrhythmias |
| 04/08/2008 | US7355050 (Meth)acrylate amide acetals |
| 04/08/2008 | US7354946 Biarylurea derivatives |
| 04/08/2008 | US7354929 6-benzyl-3-(4-chlorophenyl)-2-(2,4-dichlorophenyl)-2,6-dihydropyrazolo[3,4-c]pyridin-7-one; eating and psychological disorders; obesity, alcoholism |
| 04/08/2008 | US7354917 Oxabispidine compounds and their use in the treatment of cardiac arrhythmias |
| 04/08/2008 | US7354916 Tumor suppression agents with reduced side effects; anticancer; antibacterial and antiviral |
| 04/08/2008 | CA2337382C Process for the preparation of an indole derivative |
| 04/03/2008 | WO2008039359A2 Bicyclic pyrimidine kinase inhibitors |
| 04/03/2008 | WO2008037888A2 Tetracyclic compounds, process for the preparation thereof pharmaceutical compositions comprising the same and use thereof as dopaminergic receptor ligands |
| 04/03/2008 | WO2008037746A1 Pyridooxazepine progesteron receptor modulators |
| 04/03/2008 | WO2008037011A1 Polycyclic agents for the treatment of respiratory syncytial virus infections |
| 04/03/2008 | WO2007124494A3 Enantioselectve reactions catalyzed by chiral triazolium salts |
| 04/03/2008 | CA2664376A1 Polycyclic agents for the treatment of respiratory syncytial virus infections |
| 04/03/2008 | CA2664120A1 Pyridooxazepine progesteron receptor modulators |
| 04/02/2008 | EP1905775A1 Tetracyclic compounds, method of preparing them, pharmaceutical compositions containing them and their use as dopamine receptors ligands |
| 04/02/2008 | EP1905773A2 Compounds and methods for inhibiting mitotic progression by inhibition of aurora kinase |
| 04/02/2008 | EP1904505A1 Biologically active compounds obtainable from sorangium cellulosum |
| 04/02/2008 | EP1904504A2 Inhibitors of vegf receptor and hgf receptor signaling |
| 04/02/2008 | EP1904457A2 Compositions and methods for inhibition of the jak pathway |
| 04/02/2008 | EP1904057A2 Methods of treatment using hydroquinone ansamycins |
| 04/02/2008 | EP1697384B1 Pyrido- and pyrimidopyrimidine derivatives as anti-proliferative agents |
| 04/02/2008 | CN101155816A (1, 10b-dihydro-2-(aminoalkyl- phenyl)-5h-pyraz0l0 [1,5-c] [1,3] benz0xazin-5-yl) phenyl methanone derivatives as HIV viral repliation inhibitors |
| 04/02/2008 | CN101153043A Tetracyclic compounds, a process for their preparation and pharmaceutical compositions containing them |
| 04/02/2008 | CN101153041A 1,2,3-triazole 1,3-nitrogen heterocyclic, producing method and application of the same |
| 04/02/2008 | CN100378108C Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them |
| 04/02/2008 | CN100378107C Oxazolo-and-furopyrimidines and their use as medicaments against tumors |
| 04/02/2008 | CN100378080C Precursor of Lisinopril compound and synthesizing method |
| 04/01/2008 | US7351825 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) (MMP) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis |
| 04/01/2008 | US7351821 Oxabispidine compounds useful in the treatment of cardiac arrhythmias |
| 04/01/2008 | US7351707 Spiroazacyclic compounds as monoamine receptor modulators |
| 04/01/2008 | US7351481 electrical stability, better charge transporting capability, a high glass transition temperature, and does not crystallize; high-efficiency, low-voltage, high-luminance, long-lifespan; durability; color purity |
| 03/27/2008 | WO2008035629A1 Pyrazolopyrimidine derivative |
| 03/27/2008 | WO2008035109A1 Rifaximin |
| 03/27/2008 | WO2008034973A1 Process for preparing n-alkyl naltrexone halides |
| 03/27/2008 | WO2008008431A3 Heteroaryl sulfonamides and ccr2/ccr9 |
| 03/27/2008 | WO2008000469A3 Nicotinic agonists selective for the alpha7 receptor subtype, the process for the preparation thereof and pharmaceutical compositions therefrom |
| 03/27/2008 | WO2007117381A9 2 -aminopyridine analogs as glucokinase activators |
| 03/27/2008 | US20080076793 Use of an ascomycin for the treatment of blepharitis |
| 03/27/2008 | CA2664247A1 Inhibitors of phosphodiesterase type-iv |
| 03/27/2008 | CA2663776A1 Rifaximin in an amorphous form |
| 03/27/2008 | CA2663509A1 Process for preparing n-alkyl naltrexone halides |
| 03/26/2008 | EP1902050A1 Oxazolidinone derivatives and use thereof as antibiotics |
| 03/26/2008 | EP1902044A1 5-htx modulators |
| 03/25/2008 | US7348339 2-(4-amino-furazan-3-yl)-1-ethyl-N-[(2R)-2-morpholinylmethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide; Mitogen- and Stress-Activated Protein (MSK) and Rho (guanosine triphosphate) 1 or 2 kinase inhibitor; neurodegenerative diaeases; antiinflammatory, anticarcinogenic, antiviral and antibacterial agent |
| 03/25/2008 | US7348336 Inhibitors of IkB kinase (I Kappa B Kinase); 1-acetyl-7-bromo- beta -carboline; antiinflammatory and anticarcinogenic agent; asthma, osteoarthritis, rheumatoid arthritis, Alzheimer's disease, infections, and cardiac infarct |
| 03/25/2008 | US7348148 Polynucleotide analog with polyether, polythioether, polyether sulfone, and/or and polyether sulfoxide linkages; antisense drug therapy |
| 03/25/2008 | CA2359987C 2-amino-benzoxazinone derivatives for the treatment of obesity |
| 03/20/2008 | WO2008031594A1 Benzoxazoles and oxazolopyridines being useful as janus kinases inhibitors |
| 03/20/2008 | WO2006094187A3 Phthalazine, aza- and diaza-phthalazine compounds and methods of use |
| 03/20/2008 | US20080071083 Methods for minimizing thioamide impurities |
| 03/20/2008 | US20080071082 Heteroatoms-Containing Tricyclic Compounds |