Patents for C07D 498 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms (21,960) |
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12/23/2014 | US8916593 Alkoxy-substituted 2-aminopyridines as ALK inhibitors |
12/23/2014 | US8916584 Benzisoxazoles and azabenzisoxazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction |
12/23/2014 | US8916580 Spiro-oxindole compounds and their use as therapeutic agents |
12/23/2014 | US8916577 Tricyclic derivatives, process for their preparation and their use as kinase inhibitors |
12/23/2014 | US8916549 Thienooxazepine derivative |
12/18/2014 | US20140371458 Process for the preparation of morphine analogs via the reaction of organometallic reagents with an oxazolidine derived from morphinans |
12/18/2014 | US20140371212 Bace inhibitors |
12/18/2014 | US20140371206 Bromodomain inhibitors and uses thereof |
12/17/2014 | CN104220428A 杀真菌嘧啶化合物 Fungicidal pyrimidine compounds |
12/17/2014 | CN104211717A N-苯甲酰基-星孢素的多晶型形式iii和iv N- benzoyl - polymorph form staurosporine of iii and iv |
12/17/2014 | CN104211716A 雷帕霉素的制备方法 Preparation of rapamycin |
12/17/2014 | CN104211715A 雷帕霉素的39-去甲氧基衍生物 Rapamycin 39- to methoxy derivative |
12/17/2014 | CN102807509B 稠合多环化合物和使用该化合物的有机发光器件 Condensed polycyclic compounds and the use of organic light emitting device of the compound |
12/17/2014 | CN102245585B 环状碳化二亚胺化合物 Cyclic carbodiimide compound |
12/17/2014 | CN102203062B 用于合成8-[{i-(3,5-双-(三氟甲基)苯®)-乙氧基)甲基]-8-苯基-1,7-二氣杂-螺[4.5]癸-2-酮化合物的方法和中间体 For the synthesis of 8 - [{i- (3,5- bis - (trifluoromethyl) benzene ®) - ethoxy) methyl] -8-phenyl-1,7-gas hybrid - spiro [4.5 ] dec-2-one compound to processes and intermediates |
12/17/2014 | CN101965353B 共价连接到取代苯基噁唑烷酮的双环硝基咪唑类 Covalently attached to a substituted phenyl oxazolidinone of bicyclic nitroimidazoles |
12/16/2014 | US8912179 Heterocyclyl compounds as histamine H3 receptor ligands |
12/16/2014 | US8912170 Prodrugs of 2,4-pyrimidinediamine compounds and their uses |
12/11/2014 | US20140364601 Process |
12/11/2014 | US20140364444 Fused heterocyclic compound and use thereof for pest control |
12/11/2014 | US20140364429 Antiviral compounds highly effective as hcv-ns5a inhibitor |
12/10/2014 | CN104203959A 雷帕霉素40-o-环状烃酯、组合物和方法 Rapamycin 40-o- cyclic hydrocarbon esters, compositions and methods |
12/10/2014 | CN104203958A 二环杂环衍生物、其制备及治疗用途 Bicyclic heterocyclic derivatives, their preparation and therapeutic use |
12/10/2014 | CN104203937A 作为btk活性的抑制剂的8-氟酞嗪-1(2h)-酮化合物 Btk activity as inhibitors of 8-fluoro-phthalazine -1 (2h) - keto compound |
12/10/2014 | CN104193763A 一种滑桃树新的分离纯化方法 A new method for the separation and purification of peach slip |
12/10/2014 | CN104193750A 通过抑制极光激酶抑制有丝分裂的化合物和方法 The compounds and methods of Aurora kinase inhibition by inhibiting mitosis |
12/10/2014 | CN104193740A 作为沉默调节蛋白调节剂的苯并咪唑类和相关的类似物 As a sirtuin modulators benzimidazole class and related analogs |
12/10/2014 | CN102887889B 杂环取代的嘧啶类化合物 Heterocyclic substituted pyrimidine compounds |
12/10/2014 | CN102812005B β-分泌酶抑制剂 β- secretase inhibitors |
12/10/2014 | CN102807543B 生物内源性氧化剂的检测试剂及方法 Biological endogenous oxidant detection reagent and method |
12/10/2014 | CN102781432B 利福昔明粉末、制备其的方法和用于获得长效作用的含所述利福昔明的控释组合物 Rifaximin powder, and a process for preparing thereof for obtaining a long-lasting effect of the controlled-release composition comprising the rifaximin |
12/09/2014 | US8907104 Synthesis of enone intermediate |
12/09/2014 | US8907095 Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 |
12/09/2014 | US8907093 Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring |
12/09/2014 | US8907087 Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors |
12/09/2014 | US8906929 Inhibitors of human immunodeficiency virus replication |
12/09/2014 | US8906904 Alkoxy pyrazoles as soluble guanylate cyclase activators |
12/04/2014 | US20140357643 Derivatives of Betulin |
12/04/2014 | US20140357627 Imidazopyrazine syk inhibitors |
12/04/2014 | US20140357625 Diazepinone derivatives |
12/04/2014 | US20140357598 Prodrugs of 2,4-Pyrimidinediamine Compounds and Their Uses |
12/04/2014 | US20140356873 Derivatives of 1,2-dihydro-7-hydroxyquinolines Containing Fused Rings |
12/04/2014 | US20140356417 Modified drugs for use in liposomal nanoparticles |
12/02/2014 | US8901345 Process for preparation of optically active diamine derivative salt |
12/02/2014 | US8901302 Pyrazino[2,3-D]isoxazole derivative which is useful as a production intermediate of pyrazine carboxamide derivative |
12/02/2014 | US8901175 Use of opioids or opioid mimetics for the treatment of resistant cancer patients |
12/02/2014 | US8901164 Amphipathic and other double-sided alpha-helix mimetics based on a 1,2-diphenylacetylene scaffold |
12/02/2014 | US8901152 Inhibitors of diacylglycerol O-acyltransferase type 1 enzyme |
12/02/2014 | US8901149 Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications |
12/02/2014 | US8901141 Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them |
12/02/2014 | US8901115 Cyclic P1 linkers as factor XIa inhibitors |
12/02/2014 | US8901112 Spirocyclic aminoquinolones as GSK-3 inhibitors |
11/27/2014 | US20140350253 Asymmetric electrophilic fluorination using an anionic chiral phase-transfer catalyst |
11/27/2014 | US20140350246 Nitrogen-containing heterocyclic compounds and methods of making the same |
11/27/2014 | US20140350244 Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors |
11/27/2014 | US20140350242 Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating |
11/27/2014 | US20140350034 Aminopyridine derivatives as plasma kallikrein inhibitors |
11/27/2014 | US20140350004 Amorphous form of dolutegravir |
11/27/2014 | US20140349992 Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof |
11/25/2014 | US8895733 Triazine-oxadiazoles |
11/25/2014 | US8895549 Aminoalcohol substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
11/25/2014 | US8895545 Acrylamide derivatives as Fab I inhibitors |
11/25/2014 | US8895306 Oxadiazoline ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
11/20/2014 | US20140343276 Macrocycles as factor xia inhibitors |
11/20/2014 | US20140343059 Novel piperazines, pharmaceutical compositions and methods of use thereof |
11/20/2014 | US20140343039 Process for preparing cephalotaxine esters |
11/20/2014 | US20140343032 Novel 6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection |
11/20/2014 | US20140341851 Novel benzimidazole derivatives |
11/18/2014 | US8889877 Processes for preparing pyridinone carboxylic acid aldehydes |
11/18/2014 | US8889871 Hepatitis C virus inhibitors |
11/18/2014 | US8889855 Preparation of maytansinoid esters |
11/18/2014 | US8889854 C-17 bicyclic amines of triterpenoids with HIV maturation inhibitory activity |
11/18/2014 | US8889718 Thiazole derivatives |
11/18/2014 | US8889711 Pyrazolopyridine derivatives as anticancer agent |
11/18/2014 | US8889706 Soluble mTOR complexes and modulators thereof |
11/18/2014 | US8889671 Compounds and methods for treating bacterial infections |
11/13/2014 | US20140336374 Process and intermediates for the production of ccr2 antagonists |
11/13/2014 | US20140336184 Method to enhance cognition |
11/13/2014 | US20140336177 Inhibitors of the renal outer medullary potassium channel |
11/13/2014 | US20140336169 Imidazopyrazine syk inhibitors |
11/13/2014 | US20140336158 Nk1 antagonists |
11/11/2014 | US8883833 Substituted benzoazole PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders |
11/11/2014 | US8883826 Alkynyl derivatives as modulators of metabotropic glutamate receptors |
11/11/2014 | US8883819 Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension |
11/11/2014 | US8883807 Piperidinone carboxamide indane CGRP receptor antagonists |
11/11/2014 | US8883799 Tricyclic PI3K inhibitor compounds and methods of use |
11/11/2014 | US8883795 Polymorphic forms of Rifaximin |
11/11/2014 | US8883786 Glucocorticoid receptor antagonists |
11/11/2014 | US8883782 Spiro-tetracyclic ring compounds as beta-secretase modulators and methods of use |
11/06/2014 | US20140330007 2,4-pyrimidinediamine compounds and their uses |
11/06/2014 | US20140329820 Triazine Derivatives |
11/06/2014 | US20140329808 Tocotrienol derivatives and associated methods |
11/06/2014 | US20140329798 Substituted cyclopropyl compounds useful as gpr119 agonists |
11/04/2014 | US8877771 Treatment of solid tumors with rapamycin derivatives |
11/04/2014 | US8877770 Polymorph of rifaximin and process for the preparation thereof |
11/04/2014 | US8877750 2-oxy-benzoxazinone derivatives for the treatment of obesity |
11/04/2014 | US8877742 Compounds |
11/04/2014 | US8877706 Maytansinoid derivatives |
10/30/2014 | US20140323476 Peptide deformylase inhibitors |
10/30/2014 | US20140323470 Kinase inhibitors |