Patents
Patents for C07D 461 - Heterocyclic compounds containing indolo [3, 2, 1-d, e] pyrido [3, 2, 1-i, j] [1, 5]-naphthyridine ring systems, e.g. vincamine (286)
03/1983
03/29/1983CA1143735A1 Synthesis of vincaminic acid derivatives
01/1983
01/25/1983CA1140121A1 Process for preparing 10-halogen-e-homo eburnanes
01/18/1983US4369175 Stable resinates as vasodilators
12/1982
12/28/1982US4366157 Novel polycyclic indole derivatives
12/21/1982US4364947 Resistance to deactivation
12/14/1982CA1137473A1 Halogenated 15-hydroxy-e-homoeburnane derivatives and a process for the preparation thereof
12/07/1982US4362730 Vincamine saccharinate and a pharmaceutical composition containing it dissolved therein
12/07/1982CA1137083A1 Process for the preparation of 15- hiydroxyimino-homoeburnane derivatives
11/1982
11/23/1982CA1136139A1 Polycyclic indole derivatives
10/1982
10/26/1982US4356305 Process for the preparation of halovincamone derivatives
10/06/1982EP0061654A1 Vincamine cyclamate, process for its preparation and medicaments containing it
08/1982
08/17/1982US4345082 Process for the preparation of hydroxyamino-eburnane derivatives and octahydroindoloquinolizine intermediates
08/10/1982US4343738 Intermediates for vincamine
05/1982
05/26/1982EP0052238A1 A new vincamine derivative, a method for its preparation and pharmaceutical compositions containing it
05/04/1982US4328231 Method of treating psoriasis
04/1982
04/28/1982EP0050492A1 1,1-Disubstituted-hexahydro-indolo(2,3-a)quinolizine derivatives and their use in the enantioselective synthesis of optically active 14-oxo-E-homo-eburnane derivatives
03/1982
03/03/1982EP0046506A1 Vincamine saccharinate and drug containing it
02/1982
02/17/1982EP0045918A1 A process for the synthesis of vincamine and related indole alkaloids
02/16/1982US4316029 Synthesis of vincaminic acid derivatives
02/16/1982US4316028 Process for producing eburnane derivatives
02/10/1982EP0045602A1 Novel polycyclic indole derivatives
02/09/1982US4315011 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
02/09/1982US4314939 Process for the preparation of 15-hydroxyimino-E-homoeburnane and intermediates therefor
02/09/1982CA1117939A1 Derivatives of eburnamomine and related method of manufacturing
12/1981
12/30/1981EP0042818A1 Process for the preparation of delayed-release vincamine compositions, the vincamine compositions so obtained and drugs containing them
12/30/1981EP0042526A1 Process for producing apovincaminic acid esters and their salts
12/02/1981EP0041030A1 Compositions for topical use containing Ergot or Vinca Rosea alkaloids for treatment of hyperseborrhoea, and their preparation
12/01/1981US4303584 Method of preparing vincristine
11/1981
11/25/1981EP0040507A1 New vincamine derivatives, their production and pharmaceutical compositions containing them
10/1981
10/28/1981EP0038619A2 Process for preparing vincamine and related alkaloids
10/07/1981EP0037289A1 Method of preparing a vinca dimer
09/1981
09/22/1981US4291038 Cerebral vasodilating 20,21-dinoreburnamenine derivatives
09/22/1981CA1109418A1 Containers and closure assemblies
08/1981
08/25/1981US4285950 Effecting cyclization by treating a 1-(2-hydroxy-2-carbalkoxyethyl)-9-halo-octahydroindoloquinolizine with a strong base
08/25/1981US4285949 Vincamine derivatives, their preparation and therapeutical use
08/25/1981US4285865 Process for the preparation of halogenated 15-hydroxy-E-homoeburnane compounds
08/11/1981US4283401 Process for the preparation of 11-bromo-vincaminic acid ester derivatives and their use in protecting animals against cerebral hypoxy
05/1981
05/27/1981EP0029117A1 10-Bromosandwicine and 10-bromoisosandwicine, as well as their additions salts with pharmacolical acceptable acids process for their preparation and their use
05/27/1981EP0029116A1 N(b)-quaternary 10-bromo-sandwicine and 10-bromo-isosandwicine derivatives, process and intermediates for preparing the derivatives and medicaments containing these derivatives
05/27/1981EP0029115A1 N(b)-quaternary 10-bromo-ajmaline and 10-bromo-isoajmaline derivatives, process and intermediates for preparing the derivatives and medicaments containing the derivatives
05/12/1981US4267328 1-Phenylpiperazines
04/1981
04/28/1981CA1100135A1 Method for the preparation of apovincamine from vincamine and epivincamine
02/1981
02/10/1981CA1095520A1 Process for the preparation of new derivatives of 20, 21-dinoreburnamenin
01/1981
01/07/1981EP0021923A1 Process for the preparation of vincamine derivatives
09/1980
09/16/1980CA1085827A1 Derivatives of vincamine and apovincamine and related preparation process
09/02/1980CA1084931A1 Process for the preparation of vincamine and of related alkaloids
07/1980
07/23/1980EP0013315A2 Eburnane derivatives, their synthesis and pharmaceutical compositions containing them
02/1980
02/26/1980US4190658 Oxygenators, cerebral vasoregulators
01/1980
01/29/1980CA1070692A1 (-)-11-METHOXY-14-HYDROXYMETHYL-3.alpha.,16.alpha._EBURNAMINE AND DERIVATIVES THEREOF
01/22/1980CA1070310A1 Derivatives of vincamine, methods for their preparation and related pharmaceutical compositions
11/1979
11/20/1979CA1066706A1 14,15-dihydro-eburnamenine compounds
11/20/1979CA1066705A1 3,4-dehydro-14,15-dihydro-eburnamenine compounds
10/1979
10/16/1979CA1064496A1 Preparation of a new cincamine salt and compound thus obtained
08/1979
08/07/1979US4163851 Vasodilator alkaloids
05/1979
05/22/1979CA1055031A1 Process for the preparation of vincamine and other indole alkaloids
05/16/1979EP0001940A1 Derivatives of eburnamenine, their preparation and their therapeutical application
04/1979
04/03/1979CA1051899A1 Vincamine compounds
04/03/1979CA1051898A1 Preparation of vincamine 2-ketoglutarate
03/1979
03/27/1979US4146643 Halo-, hydroxy-, alkyl-, and alkoxy-vincamine derivatives
03/20/1979US4145552 Forming carbanions; oxidation, reduction
03/07/1979EP0001021A2 Derivatives of pentacyclic alcaloids, method for their preparation, application in the synthesis of products of the eburnamonine group and pharmaceutical compositions
02/1979
02/20/1979US4140777 Cerebral vasodilating 6-substituted vincamines
01/1979
01/30/1979US4137316 Anti-depressive vincamine pyridoxal-5-phosphate
01/16/1979CA1046514A1 Dihydroapovincaminic acid amines
10/1978
10/31/1978US4123535 Psychostimulating 14-amino-14,15-dihydroeburnamenines
10/24/1978US4122179 Acid addition salts of vincamine and apovincamine
10/17/1978US4120858 Hypotensive, arteriosclerosis agents
09/1978
09/26/1978CA1039284A1 Esters of dihydroapovincaminic acid
08/1978
08/22/1978US4108996 (-)-Apovincaminol lauric acid ester and cerebral vasodilatory composition thereof
03/1978
03/14/1978US4078696 Containers and closures therefor
12/1977
12/27/1977US4065458 Eburnamenine derivatives
11/1977
11/08/1977US4057550 14,15-dihydro-14-cyano-eburnamenines, vasodilation
10/1977
10/18/1977US4054571 Nitrogen-containing polycyclic compounds and a process for the preparation thereof
08/1977
08/30/1977US4045443 Organic compounds
07/1977
07/12/1977US4035370 Vasodilatory, apovincaninic acid ethyl ester
07/05/1977US4033969 Cerebro-vascular disorders
05/1977
05/03/1977US4021430 Dihydroapovincaminic acid amines
03/1977
03/08/1977US4011330 Central nervous system disorders involving anoxia factor
01/1977
01/04/1977US4001251 Apovincaldehyde
10/1976
10/19/1976US3987177 Vincaminic acid esters
10/19/1976US3987049 Esters of dihydroapovincaminic acid
09/1976
09/21/1976US3982002 Vincamine 2-ketoglutarate and compositions containing vincamine 2-ketoglutarate
09/07/1976US3979395 Process for the preparation of vincamine and other indole alkaloids
06/1976
06/29/1976US3966745 Vinvamine series cycloalkyl-alkyl esters
04/1976
04/13/1976US3950345 Process for the preparation of cis-vincamine
02/1976
02/10/1976US3937709 Enamines, alkylation, methyl a-bromomethyl acrylate, reduction, oxidation, cyclization
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