Patents for C07D 461 - Heterocyclic compounds containing indolo [3, 2, 1-d, e] pyrido [3, 2, 1-i, j] [1, 5]-naphthyridine ring systems, e.g. vincamine (286) |
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03/29/1983 | CA1143735A1 Synthesis of vincaminic acid derivatives |
01/25/1983 | CA1140121A1 Process for preparing 10-halogen-e-homo eburnanes |
01/18/1983 | US4369175 Stable resinates as vasodilators |
12/28/1982 | US4366157 Novel polycyclic indole derivatives |
12/21/1982 | US4364947 Resistance to deactivation |
12/14/1982 | CA1137473A1 Halogenated 15-hydroxy-e-homoeburnane derivatives and a process for the preparation thereof |
12/07/1982 | US4362730 Vincamine saccharinate and a pharmaceutical composition containing it dissolved therein |
12/07/1982 | CA1137083A1 Process for the preparation of 15- hiydroxyimino-homoeburnane derivatives |
11/23/1982 | CA1136139A1 Polycyclic indole derivatives |
10/26/1982 | US4356305 Process for the preparation of halovincamone derivatives |
10/06/1982 | EP0061654A1 Vincamine cyclamate, process for its preparation and medicaments containing it |
08/17/1982 | US4345082 Process for the preparation of hydroxyamino-eburnane derivatives and octahydroindoloquinolizine intermediates |
08/10/1982 | US4343738 Intermediates for vincamine |
05/26/1982 | EP0052238A1 A new vincamine derivative, a method for its preparation and pharmaceutical compositions containing it |
05/04/1982 | US4328231 Method of treating psoriasis |
04/28/1982 | EP0050492A1 1,1-Disubstituted-hexahydro-indolo(2,3-a)quinolizine derivatives and their use in the enantioselective synthesis of optically active 14-oxo-E-homo-eburnane derivatives |
03/03/1982 | EP0046506A1 Vincamine saccharinate and drug containing it |
02/17/1982 | EP0045918A1 A process for the synthesis of vincamine and related indole alkaloids |
02/16/1982 | US4316029 Synthesis of vincaminic acid derivatives |
02/16/1982 | US4316028 Process for producing eburnane derivatives |
02/10/1982 | EP0045602A1 Novel polycyclic indole derivatives |
02/09/1982 | US4315011 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow |
02/09/1982 | US4314939 Process for the preparation of 15-hydroxyimino-E-homoeburnane and intermediates therefor |
02/09/1982 | CA1117939A1 Derivatives of eburnamomine and related method of manufacturing |
12/30/1981 | EP0042818A1 Process for the preparation of delayed-release vincamine compositions, the vincamine compositions so obtained and drugs containing them |
12/30/1981 | EP0042526A1 Process for producing apovincaminic acid esters and their salts |
12/02/1981 | EP0041030A1 Compositions for topical use containing Ergot or Vinca Rosea alkaloids for treatment of hyperseborrhoea, and their preparation |
12/01/1981 | US4303584 Method of preparing vincristine |
11/25/1981 | EP0040507A1 New vincamine derivatives, their production and pharmaceutical compositions containing them |
10/28/1981 | EP0038619A2 Process for preparing vincamine and related alkaloids |
10/07/1981 | EP0037289A1 Method of preparing a vinca dimer |
09/22/1981 | US4291038 Cerebral vasodilating 20,21-dinoreburnamenine derivatives |
09/22/1981 | CA1109418A1 Containers and closure assemblies |
08/25/1981 | US4285950 Effecting cyclization by treating a 1-(2-hydroxy-2-carbalkoxyethyl)-9-halo-octahydroindoloquinolizine with a strong base |
08/25/1981 | US4285949 Vincamine derivatives, their preparation and therapeutical use |
08/25/1981 | US4285865 Process for the preparation of halogenated 15-hydroxy-E-homoeburnane compounds |
08/11/1981 | US4283401 Process for the preparation of 11-bromo-vincaminic acid ester derivatives and their use in protecting animals against cerebral hypoxy |
05/27/1981 | EP0029117A1 10-Bromosandwicine and 10-bromoisosandwicine, as well as their additions salts with pharmacolical acceptable acids process for their preparation and their use |
05/27/1981 | EP0029116A1 N(b)-quaternary 10-bromo-sandwicine and 10-bromo-isosandwicine derivatives, process and intermediates for preparing the derivatives and medicaments containing these derivatives |
05/27/1981 | EP0029115A1 N(b)-quaternary 10-bromo-ajmaline and 10-bromo-isoajmaline derivatives, process and intermediates for preparing the derivatives and medicaments containing the derivatives |
05/12/1981 | US4267328 1-Phenylpiperazines |
04/28/1981 | CA1100135A1 Method for the preparation of apovincamine from vincamine and epivincamine |
02/10/1981 | CA1095520A1 Process for the preparation of new derivatives of 20, 21-dinoreburnamenin |
01/07/1981 | EP0021923A1 Process for the preparation of vincamine derivatives |
09/16/1980 | CA1085827A1 Derivatives of vincamine and apovincamine and related preparation process |
09/02/1980 | CA1084931A1 Process for the preparation of vincamine and of related alkaloids |
07/23/1980 | EP0013315A2 Eburnane derivatives, their synthesis and pharmaceutical compositions containing them |
02/26/1980 | US4190658 Oxygenators, cerebral vasoregulators |
01/29/1980 | CA1070692A1 (-)-11-METHOXY-14-HYDROXYMETHYL-3.alpha.,16.alpha._EBURNAMINE AND DERIVATIVES THEREOF |
01/22/1980 | CA1070310A1 Derivatives of vincamine, methods for their preparation and related pharmaceutical compositions |
11/20/1979 | CA1066706A1 14,15-dihydro-eburnamenine compounds |
11/20/1979 | CA1066705A1 3,4-dehydro-14,15-dihydro-eburnamenine compounds |
10/16/1979 | CA1064496A1 Preparation of a new cincamine salt and compound thus obtained |
08/07/1979 | US4163851 Vasodilator alkaloids |
05/22/1979 | CA1055031A1 Process for the preparation of vincamine and other indole alkaloids |
05/16/1979 | EP0001940A1 Derivatives of eburnamenine, their preparation and their therapeutical application |
04/03/1979 | CA1051899A1 Vincamine compounds |
04/03/1979 | CA1051898A1 Preparation of vincamine 2-ketoglutarate |
03/27/1979 | US4146643 Halo-, hydroxy-, alkyl-, and alkoxy-vincamine derivatives |
03/20/1979 | US4145552 Forming carbanions; oxidation, reduction |
03/07/1979 | EP0001021A2 Derivatives of pentacyclic alcaloids, method for their preparation, application in the synthesis of products of the eburnamonine group and pharmaceutical compositions |
02/20/1979 | US4140777 Cerebral vasodilating 6-substituted vincamines |
01/30/1979 | US4137316 Anti-depressive vincamine pyridoxal-5-phosphate |
01/16/1979 | CA1046514A1 Dihydroapovincaminic acid amines |
10/31/1978 | US4123535 Psychostimulating 14-amino-14,15-dihydroeburnamenines |
10/24/1978 | US4122179 Acid addition salts of vincamine and apovincamine |
10/17/1978 | US4120858 Hypotensive, arteriosclerosis agents |
09/26/1978 | CA1039284A1 Esters of dihydroapovincaminic acid |
08/22/1978 | US4108996 (-)-Apovincaminol lauric acid ester and cerebral vasodilatory composition thereof |
03/14/1978 | US4078696 Containers and closures therefor |
12/27/1977 | US4065458 Eburnamenine derivatives |
11/08/1977 | US4057550 14,15-dihydro-14-cyano-eburnamenines, vasodilation |
10/18/1977 | US4054571 Nitrogen-containing polycyclic compounds and a process for the preparation thereof |
08/30/1977 | US4045443 Organic compounds |
07/12/1977 | US4035370 Vasodilatory, apovincaninic acid ethyl ester |
07/05/1977 | US4033969 Cerebro-vascular disorders |
05/03/1977 | US4021430 Dihydroapovincaminic acid amines |
03/08/1977 | US4011330 Central nervous system disorders involving anoxia factor |
01/04/1977 | US4001251 Apovincaldehyde |
10/19/1976 | US3987177 Vincaminic acid esters |
10/19/1976 | US3987049 Esters of dihydroapovincaminic acid |
09/21/1976 | US3982002 Vincamine 2-ketoglutarate and compositions containing vincamine 2-ketoglutarate |
09/07/1976 | US3979395 Process for the preparation of vincamine and other indole alkaloids |
06/29/1976 | US3966745 Vinvamine series cycloalkyl-alkyl esters |
04/13/1976 | US3950345 Process for the preparation of cis-vincamine |
02/10/1976 | US3937709 Enamines, alkylation, methyl a-bromomethyl acrylate, reduction, oxidation, cyclization |