| Patents for C07D 461 - Heterocyclic compounds containing indolo [3, 2, 1-d, e] pyrido [3, 2, 1-i, j] [1, 5]-naphthyridine ring systems, e.g. vincamine (286) |
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| 02/04/2015 | CN104327073A 一种长春西汀的半合成生产方法 A semi-synthetic production methods vinpocetine |
| 01/21/2015 | CN102952128B 长春西汀的精制方法 Purification method vinpocetine |
| 12/24/2014 | CN104230921A 一种长春胺乙酯的制备方法 A process for preparing ethyl vincamine |
| 07/09/2014 | CN103910722A 一种长春西汀化合物及其制备方法 One kind of vinpocetine compounds and methods |
| 06/25/2014 | CN103880838A 一种长春西汀半合成新合成工艺 One kind of semi-synthetic vinpocetine new synthesis process |
| 06/04/2014 | CN103833751A Synthetic process of related impurity A of vinpocetine |
| 05/07/2014 | CN102702191B 长春西汀的合成方法 Synthesis vinpocetine |
| 04/02/2014 | CN102164921B Process for the preparation of vinpocetine and apovincamine |
| 03/26/2014 | CN103664934A Preparation method for vinpocetine |
| 02/05/2014 | CN103554102A Simple synthetic method of vinpocetine |
| 01/01/2014 | CN103483336A Preparation method of byproduct in vinpocetine preparation process |
| 12/24/2013 | US8614321 Benzoimidazolyl-pyrazine compounds for inflammation and immune-related uses |
| 11/12/2013 | US8580814 Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| 10/02/2013 | CN103333166A Method for catalyzed synthesis of vinpocetine by using solid acid and alkali |
| 09/18/2013 | CN103304563A Method for efficiently synthesizing vinpocetine from vincamine |
| 09/11/2013 | CN103288822A Preparation method of vinpocetine |
| 08/07/2013 | CN103232452A Industrialized semi-synthesis process of vincamine |
| 05/30/2013 | WO2013076646A1 A new diaza-benzofluoranthene derivative as drug |
| 05/29/2013 | CN103121998A Vinpocetine compound and drug composition thereof |
| 03/06/2013 | CN102952128A Refining method of vinpocetine |
| 02/20/2013 | CN102936247A Preparation technology of high-purity vinpocetine |
| 02/06/2013 | CN102911171A Semisynthesis method of vinpocetine |
| 01/16/2013 | CN102875547A Vinpocetine compound and its preparation method |
| 01/09/2013 | CN102350083B Crystallizing tank used for vincamine |
| 10/17/2012 | CN102311432B Stable vinpocetine compound and pharmaceutical composition thereof |
| 10/17/2012 | CN102276599B Process for preparing vincamine by semisynthetic method |
| 10/03/2012 | CN102702192A Synthesis method of vinpocetine |
| 10/03/2012 | CN102702191A Synthesis method of vinpocetine |
| 10/03/2012 | CN102040606B Synthetic method of vinpocetine |
| 07/11/2012 | CN102558170A Method for preparing optically pure cis apovincaminic acid ester |
| 06/06/2012 | CN102485723A Semi-synthesis of vinpocetine through one kettle way and preparation of water-soluble vinpocetine salt |
| 06/05/2012 | CA2520000C Compositions and methods for treating cancer |
| 04/25/2012 | CN202199159U 一种长春胺用结晶罐 One kind Vincamine crystalline tank |
| 04/25/2012 | CN202199158U 一种长春西汀专用结晶罐 One kind of special crystallization tank vinpocetine |
| 04/25/2012 | CN102423543A 一种长春西汀专用结晶罐 One kind of special crystallization tank vinpocetine |
| 02/15/2012 | CN102350083A Crystallizing tank used for vincamine |
| 01/11/2012 | CN102311432A Stable vinpocetine compound and pharmaceutical composition thereof |
| 12/14/2011 | CN102276599A 半合成法长春胺的制备工艺 Preparation of semi-synthetic method vincamine |
| 08/24/2011 | CN102164921A Process for the preparation of vinpocetine and apovincamine |
| 07/20/2011 | EP2344489A1 Process for the preparation of vinpocetine and apovincamine |
| 06/29/2011 | CN102108082A Industrialized semisynthesis of medicine-vincamine for treating cerebral ischemia |
| 06/01/2011 | CN1953977B Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 05/04/2011 | CN102040606A Synthetic method of vinpocetine |
| 12/29/2010 | CN101928286A Pervone derivative and preparation method thereof |
| 11/17/2010 | EP1737856B1 Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 05/06/2010 | US20100113498 Novel vinblastine derivatives, their preparation, use and pharmaceutical compositions comprising the said derivatives |
| 04/01/2010 | WO2010034647A1 Process for the preparation of vinpocetine and apovincamine |
| 03/31/2010 | EP2168963A1 Process for the preparation of vinpocetine and apovincamine |
| 04/17/2008 | US20080090803 Fatty alcohol drug conjugates |
| 04/09/2008 | CN101157699A Method for extracting vinca alkaloids extract from Vinca rosea |
| 04/08/2008 | US7354918 cerebral oxygenators and vasoregulators; antidepressant, cognition activator; sleep disorders; enantiomer mixture separated by HPLC; classical antidepressants resistance |
| 04/25/2007 | CN1953977A Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 04/19/2007 | US20070088046 cerebral oxygenators and vasoregulators; antidepressant, cognition activator; sleep disorders; enantiomer mixture separated by HPLC; classical antidepressants resistance |
| 01/03/2007 | EP1737856A1 Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 11/16/2006 | WO2005103047A8 Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 05/26/2006 | WO2006054536A1 Therapeutic agent for urolithiasis |
| 11/03/2005 | WO2005103047A1 Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 11/03/2005 | CA2563491A1 Derivatives of 14.15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof |
| 09/30/2004 | DE10311850A1 Preparation of vinpocetin used as vasodilator and nootropic agent, comprises dehydrating vincamine ester to apovincamine derivative and transesterifying |
| 04/15/2003 | CA2036337C Derivatives of 20,21-dinoreburnamenin, their preparation process and the new intermediates thus obtained, their application as drugs and the compositions containing such |
| 03/18/2003 | US6534515 20,21-dinor-eburnamenines |
| 09/11/2002 | EP0876367B1 Trans apovincaminic acid ester derivatives as drugs |
| 04/18/2002 | US20020045637 Novel 20,21-dinor-eburnamenine |
| 03/12/2002 | CA2137889C Eburnan analogs; process for preparing the same and pharmaceutical compositions containing them |
| 10/10/2001 | CN1072670C Trans-apovincaminic acid ester derivatives as drugs |
| 07/25/2000 | US6093720 An antioxidant, antiischemic as well as antiamnesic effects for inhibiting lipid peroxidation, treating various degenerative neurological diseases alzheimer's disease |
| 09/29/1999 | CN1045295C Process for prepn. of 14,15-dihydro-14-hydroxy-(3,16)-eburnamenine-14-carboxylic acid |
| 01/20/1999 | CN1205701A Trans apovincaminic acid ester derivatives as drugs |
| 12/02/1998 | CN1200733A Apovincaminic acid derivative and medicine contg. same |
| 11/11/1998 | EP0876367A1 Trans apovincaminic acid ester derivatives as drugs |
| 10/21/1998 | CN1040325C Application of 'Changchun' amine and its derivant for preparation of hair growing agent |
| 09/30/1998 | CN1040000C Process for preparing derivatives substituted in position 15 of 20, 21-dinoreburnamenine |
| 09/16/1998 | EP0864571A1 Apovincaminic acid derivative and medicine containing the same |
| 07/03/1997 | WO1997023481A1 Trans apovincaminic acid ester derivatives as drugs |
| 07/03/1997 | CA2238635A1 Trans apovincaminic acid ester derivatives as drugs |
| 06/05/1997 | WO1997019945A1 Apovincaminic acid derivative and medicine containing the same |
| 06/05/1997 | CA2238488A1 Apovincaminic acid derivatives and drugs containing the same |
| 04/22/1997 | US5622957 Inducers of tyrosine hydroxylase; treatment of depression and anxiety |
| 02/11/1997 | US5602131 EburnanE analogues |
| 02/05/1997 | CN1033973C Preparation of vincamine amino acid ester |
| 10/16/1996 | EP0737232A1 Modular design and synthesis of aminimide containing molecules |
| 07/31/1996 | EP0723441A1 Aminimide-containing molecules and materials as molecular recognition agents |
| 04/23/1996 | US5510345 Biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same |
| 03/13/1996 | CN1118348A Process for the preparation of 14,15-dihydro-14-hydroxy-(3,16)-eburnamenine-14-carboxylic acid |
| 01/17/1996 | CN1114958A Application of "changchun" amine and its derivant for preparation of hair growing agent |
| 10/17/1995 | CA1337348C Optically active 20,21-dinoreburnamenin derivatives; process for preparing the same; use thereof as drugs and pharmaceutical compositions containing them |
| 07/06/1995 | WO1995018186A1 Modular design and synthesis of aminimide containing molecules |
| 07/06/1995 | CA2179983A1 Modular design and synthesis of aminimide containing molecules |
| 06/21/1995 | EP0658557A1 Eburnane derivatives, processes for their preparation and pharmaceutical compositions containing them |
| 06/13/1995 | US5424314 Anti-anoxic |
| 03/29/1995 | EP0644885A1 Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same |
| 12/06/1994 | CA1333394C Apovincaminic acid derivatives |
| 10/25/1994 | CA1332735C 20, 21-dinoreburnamenine substituted derivatives, preparation process thereof and new intermediates so obtained, their application as drugs, and pharmaceutical compositions containing them |
| 08/02/1994 | US5334385 New alkaloid derivatives, their use and pharmaceutical formulations containing them |
| 07/26/1994 | US5332748 Substituted derivatives of 20,21-dinoreburnamenine, their preparation process and the new intermediates thus obtained, their use as medicaments and the pharmaceutical compositions containing them |
| 01/20/1994 | WO1994001102A1 Aminimide-containing molecules and materials as molecular recognition agents |
| 01/20/1994 | CA2139349A1 Aminimide-containing molecules and materials as molecular recognition agents |
| 12/23/1993 | WO1993025550A1 Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same |
| 12/23/1993 | CA2136547A1 Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same |
| 12/08/1993 | EP0573260A1 New alkaloid derivatives, their use and pharmaceutical formulations containing them |