Patents
Patents for C07D 455 - Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine (2,122)
08/2008
08/27/2008CN100413863C Novel 1,2,3-substituted indolizine derivatives, inhibitors of FGFs, method for making same and pharmaceutical compositions containing same
08/20/2008EP1485369B1 Blue 3h-naphtho- 2,1-b -pyran derivatives and use thereof
08/20/2008EP1289993B9 Caspase inhibitors and uses thereof
08/20/2008CN101245064A Process for producing hydrochloric berberine
08/14/2008WO2008096777A1 Therapeutic agent for irritable bowel syndrome
08/13/2008EP1437354B1 4-oxoquinolizine antimicrobials having 2-pyridone skeleton as partial structure
08/06/2008EP1907366A4 New imidazole derivatives, preparation method thereof and organic electronic device using the same
08/05/2008US7407964 Stable; potent; penetrates cell membranes; effectively hinders cellular apoptosis; Antiinflammatory agents, Ischemic agents, cancer, autoimmune diseases and nervous system disorders.
07/2008
07/24/2008US20080176860 8-[4-{4-[5-(Acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-4-(3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-carbonyloxy)-piperidin-1-yl]-1-cyclopropyl-7-fluoro-9-methyl; microbioside; multi-drug resistant bacteria; bacterial topoisomerases and protein synthesis inhibitor
07/24/2008US20080176833 Dihydropyridine derivatives as useful as protein kinase inhibitors
07/23/2008CN100404534C Use of berberine derivativein preparing medicament for treating type-2 diabetes, adjusting blood sugar and blood fat
07/17/2008US20080169453 Near infrared ray absorbing material and near infrared ray absorbing filter
07/16/2008CN101220026A 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
07/16/2008CN100403577C Red organic electroluminescent element
07/16/2008CN100402527C Clean kurarinol producing process
07/10/2008WO2008082715A2 Sox-based kinase sensor
07/10/2008US20080167337 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2-ol compounds and methods relating thereto
07/10/2008US20080167318 Pharmaceutically active pyrrolidine derivatives
07/09/2008CN100400537C Red fluorescent dye compound. preparation process and application thereof
07/09/2008CN100400487C Glucocorticoid receptor modulators
07/02/2008EP1937686A1 New anti-malaria derivatives of 4-aminoquinoline
07/02/2008EP1509519B1 Crystalline fluoroquinolone arginine salt form
07/01/2008US7393957 Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
06/2008
06/18/2008EP1846401B1 New 4-aminoquinoline derivatives as antimalarials
06/11/2008EP1930330A1 Pleuromutilin derivatives as antimicrobials
06/11/2008CN101195627A New application of benzo [C] phenanthridine and protopine in producing overriding resistant bacterium medicament
05/2008
05/28/2008CN100390211C High polarity polystyrene adsorption resin preparation method and its uses in separating bocconine
05/28/2008CN100390171C Method for extracting dophoridine from residual solution of matrine extracting solution from fenugreek
05/21/2008EP1599206A4 Aminocyclopentyl fused heterotricylicamide modulators of chemokine receptor activity
05/14/2008CN100387596C Preparation of 13-hexyl berberine salt and its anti-virus and antibacterial action
05/08/2008US20080108816 Process for the preparation of (s)-4-fluoromethyl-dihydro-furan-2-one
05/08/2008US20080108646 9-fluoro-6,7,-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid; optically pure isomers of Nadifloxacin; bactericide; systemic or topical Gram-positive, Gram-negative bacterial, mycobacterial and nosocomlal pathogen infections
05/08/2008US20080108645 Dihydrotetrabenazines And Pharmaceutical Compositions Containing Them
05/07/2008EP1918289A2 Crystalline fluoroquinolone arginine salt form
05/07/2008CN101172975A Method of preparing five-alkaloid composition of corydalis saxicola bunting
04/2008
04/16/2008CN101161652A Quinolizine derivatives having antibacterial activity
04/10/2008WO2008040192A1 13,13a-DIHYDROBERBERINE DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE
04/09/2008EP1907366A1 New imidazole derivatives, preparation method thereof and organic electronic device using the same
04/09/2008CN101157693A Method for preparing berberinc derivate
04/09/2008CN101157692A Berberinc derivatives, preparation method and medicinal composition and usage thereof
04/09/2008CN101157689A Complex salt of Silybin and oxymatrine or matrine and uses thereof
04/02/2008EP1904493A1 Tetrahydroprotoberberine compounds, the synthetic method and the use thereof
04/02/2008CN101153039A 13, 13a- dihydro berberine derivant, pharmaceutical composition and uses of the same
03/2008
03/27/2008US20080076925 process for the preparation of pyrido[2,1-a] isoquinoline derivatives of the formula** Image-1wherein R2, R3and R4 are as defined in the specification, comprising the steps of a) catalytic asymmetric hydrogenation of an enamine of the formula
03/20/2008US20080071087 PROCESS FOR THE PREPARATION OF PYRIDO [2,1-a] ISOQUINOLINE DERIVATIVES COMPRISING OPTICAL RESOLUTION OF AN ENAMINE
03/20/2008US20080070916 Treating disorders such as proliferative diseases, and cancer; compounds can act as probes of biological function; libraries; for example, 2-ethoxy-3-(2-hydroxyethoxyethoxyethyl)-4-(1-acetylindol-3-yl)-6-(morpholinocarbonyl)-2H-3,4-dihydropyran
03/13/2008WO2008030226A1 3h-naphth0 [2, 1-b] pyrans as photochromic dichroic dyes and optical article containing them
03/13/2008WO2007136570A3 5,6-fused pyrrolidine compounds useful as tachykinin receptor antagonists
03/11/2008US7341700 Method for recovery of metals from metal-containing materials using medium temperature pressure leaching
03/05/2008EP1732541A4 Cyclic compounds
03/05/2008CN100372845C Polycyclic compounds as potent alpha2-adrenoceptor antagonists
02/2008
02/28/2008US20080050761 Sox-based kinase sensor
02/28/2008US20080050312 Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents
02/27/2008CN101130541A Method for extracting and separating matrine and oxymatrine from trialkyl phosphine oxide inverse micellar solution
02/21/2008US20080044466 Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
02/13/2008CN101121714A Method for synthesizing 3-(2-phenylethyl)-5-[2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolin-en]-2,4-oxazolidinedione
02/07/2008WO2008015516A1 Fused tricyclic heterocycles for the treatment of schizophrenia
02/07/2008WO2008014661A1 Tetrahydroprotoberberine compounds, their manufacture, medicinal composition and uses.
01/2008
01/30/2008CN101113149A Aliphatic organic acid salt of berberine type alkaloid and preparation method and usage thereof
01/24/2008US20080016674 Method And Installation Means For Installing An Electrical Machine
01/16/2008CN101104618A Long chain alkyl berberine salt derivative, synthetic method and use
01/02/2008EP1390664A4 Materials, methods, and uses for photochemical generation of acids and/or radical species
01/02/2008CN101099286A Method and installation means for installing an electrical machine
12/2007
12/20/2007US20070293527 1-Methyl-1,3,4,5,6,11b-hexahydro-2H-11-oxa-4a-aza-benzo[a]fluoren-1-ol; alpha 2C adrergic receptors; adrenergic blocking agents; central nervous system; cognition activators; antidepressants; anxiolytic agents; peripheral nervous syster; antidiabetic agents; hypertensive agents; Raynaud's disease
12/13/2007US20070287699 Antiviral agents
11/2007
11/28/2007CN100351242C Processes and intermediates for preparing anti-cancer compounds
11/27/2007US7300732 Organophotoreceptors with azine-based compounds
11/15/2007CA2650904A1 Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents
11/14/2007EP1311506B1 Chiral fluoroquinolizinone arginine salt forms
11/07/2007EP1361225B1 Compounds substituted with bicyclic amino groups
10/2007
10/31/2007EP1289993B1 Caspase inhibitors and uses thereof
10/31/2007CN100345848C Leavo halogenated salt and its preparation process and use
10/25/2007US20070249661 Compounds for inflammation and immune-related uses
10/25/2007US20070249650 isolating and purifying quaternary ammonium alkaloid species from medicinal plant of Yan Huang Lian (Corydalis saxicola Bounting) through solvent extraction, crystallization and recrystallization; for treating viral hepatitis, hepatic injury, influenza, AIDS, tumors or arrhythmia
10/24/2007EP1846401A1 New 4-aminoquinoline derivatives as antimalarials
10/24/2007CN101058580A Method of extracting matrine by ultrasound wave method
10/24/2007CN101058575A Method of extracting and refining palmatin hydrochloride and application thereof
10/17/2007EP1844161A2 Dark quenchers, probes and other conjugates incorporating the same, their use
10/10/2007CN101050213A Fat amido substitutional berberine derviation, preparation method, and application of anticancer drugs
10/09/2007US7279472 cathepsins inhibitors such as N-(4-Cyano-methyl-piperidin-4-yl)-3-cyclohexyl-2-(3-oxo-3H-isoindol-1-ylamino)-propionamide, used for treating autoimmune diseases such as arthritis, multiple sclerosis, asthma and osteoporosis
10/03/2007EP1490361B1 Polycyclic compounds as potent alpha2-adrenoceptor antagonists
09/2007
09/20/2007US20070219227 Prodrugs of benzoquinolizine-2-carboxylic acid
09/19/2007CN101037436A L-stepholidine (l-SPD) derivatives, preparation method and usage thereof
09/11/2007US7267925 Photosensitive composition and novel compound used therefor
09/05/2007CN101028343A Total alkaloid of meadowrue corydalis and its purification and medicinal composition
09/04/2007US7265132 Peptidyl spiroheterocyclic, amidino and guanidino compounds; reversible inhibitors of the cysteine protease cathepsin S, K, F, L and B; useful in the treatment of autoimmune and other related diseases
08/2007
08/23/2007WO2007094548A2 Berberrubine derivatives having antifungal activities
08/23/2007WO2007093366A1 Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
08/23/2007CA2636617A1 Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
08/22/2007CN1332950C Improved compounds for generating chemiluminescence with peroxidase
08/15/2007EP1817834A1 Method and installation means for installing an electrical machine
08/09/2007US20070185158 Indol-4 sulfonamide derivatives, their preparation and their use 5-ht-6 as modulators
08/08/2007CN101012227A Novel 13-n-octylberberine derivative with antineoplastic action
08/07/2007US7253292 Synthesis of cyclopentadiene derivatives
08/02/2007US20070179165 Cyclic compounds
07/2007
07/26/2007WO2007067478A3 P38 kinase inhibiting agents
07/26/2007WO2007041241A3 Compositions and methods for detecting ligand-receptor interactions
07/24/2007US7247642 Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
07/18/2007CN100999522A Preparation process of palmatine
07/11/2007EP1660495B1 Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
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