Patents
Patents for C07D 455 - Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine (2,122)
11/2013
11/13/2013CN103387574A Synthetic method of epiberberine
11/07/2013US20130296360 Benzoquinoline inhibitors of vesicular monoamine transporter 2
11/06/2013CN102634225B Method for resolving and synthetizing 5(6) substitutional rhodamine isomer
10/2013
10/23/2013CN103360377A A compound used for a dye
10/22/2013US8562949 Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents
10/03/2013WO2013147586A1 A method for preparing an immunogen and a use thereof
09/2013
09/26/2013US20130252882 Antimicrobial 4-oxoquinolizines
09/25/2013CN103319479A Rheinic acid berberine ion pair compound, preparation method and applications
09/25/2013CN103319456A Dihydropyridine compounds, and compositions, preparation methods and applications thereof
09/24/2013US8540521 Benzoxazole-based fluorescent metal ion indicators
09/19/2013US20130245035 2-pyridone antimicrobial compositions
09/18/2013CN103304562A Phellodendrine monomer and preparation method of salt thereof
09/12/2013WO2013133218A1 Photoelectric conversion element, method for using same, imaging element, optical sensor, and chemical
09/11/2013CN103288821A Palmatine derivative and preparation method and application thereof
09/11/2013CN103288820A Compound 13-methyl-palmatrubine and application thereof
09/11/2013CN103288819A Salt of crinum asiaticum novacine derivative
08/2013
08/28/2013CN102174050B Method for separating and purifying coptis alkaloids by utilizing polyamide resin
08/21/2013CN103254189A Method for separating berberine hydrochloride by applying berberine hydrochloride molecular imprinting chromatographic column
08/13/2013US8507519 Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
08/01/2013US20130197227 Method of preparing tetrabenazine and dihydrotetrabenazine
07/2013
07/24/2013CN103214477A Process for separating corydalmine alkaloids by utilizing alkaline silica gel
07/24/2013CN103214410A Series of asymmetrical squarine micromolecules as well as preparation method and application thereof
07/18/2013US20130184304 Pyrido[4,3-b]indoles and methods of use
07/18/2013US20130184303 Pyrido[4,3-b]indoles and methods of use
07/17/2013CN103204850A Acetylsalicylic acid berberine salt, preparation method and application thereof
07/10/2013CN103193974A Method for preparing polyether glycol by liquefying starch
07/10/2013CN103193772A Preparation method and application of substituted aryl propionic berberine ion-pair compound
07/10/2013CN102260255B Simple and convenient synthesis method of 9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-3-isobutyl-2H-benzo[a] quinolizidine-2-ketone
07/04/2013US20130172335 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds
07/03/2013EP2610254A1 Deuterated benzoquinoline derivatives as inhibitors of vesicular monoamine transporter 2
06/2013
06/25/2013US8470786 Pyrroloquinolinyl-pyrrolidine-2,5-dione compositions and methods for preparing and using same
06/19/2013EP2604290A2 Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents
06/19/2013CN103159755A Alpha-glycosidase inhibitor preparation method and purpose
06/18/2013CA2443317C Materials, methods, and uses for photochemical generation of acids and/or radical species
06/12/2013CN103145703A Process technique to prepare rotundine based on different plants
06/05/2013CN103130806A Phenanthroindo(quio)lizidine alkaloid derivative, and preparation, anti-TMV activity, anti-HIV activity and anti-tumor activity thereof
05/2013
05/08/2013CN102285983B Method for modifying flumequine into 7-hydroxyflumequine
05/02/2013WO2013060274A1 Derivatives of protoberberine biological alkaloids and use of same inhibiting ulcerative colitis
05/01/2013EP2585460A1 Quinolizidine and indolizidine derivatives
04/2013
04/24/2013CN103059017A Design of comprehensive extraction process for barberry plant resources
04/24/2013CN103059016A Coptisine derivatives as well as synthesis methods and medicinal application thereof to resistance of tumors
04/24/2013CN102285981B Preparation method of fibrauretin
04/24/2013CN102015710B Azatricyclic antibiotic compounds
04/17/2013CN103044417A Novel technology method for purifying berberine in wild berberis sibirica
04/16/2013US8420818 Process for the preparation of pyrido[2,1-a] isoquinoline derivatives
04/04/2013WO2013046061A1 Pures-(-)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1h,-5h-benzo[i,j]quinolizine-2- carboxylic acid l-arginine salt tetrahydrate and a process for its preparation
04/04/2013CA2850159A1 Pure s-(-)- 9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl -1-oxo-1h,-5h-benzo[i,j]quinolizine-2-carboxylic acid l-arginine salt tetrahydrate and a process for its preparation
03/2013
03/27/2013CN102993198A Three novel intermediates used for preparing three isoquinoline alkaloids or salts thereof and preparation method thereof, and preparation method of three isoquinoline alkaloids or salts thereof
03/27/2013CN102989017A Usage of berberine or derivatives thereof in preparation of tumor diagnosis imaging agent
03/27/2013CN102093345B Method for separating out dehydrogenized turkey corn by applying silicagel column chromatography
03/13/2013CN102120742B Preparation method of tetrabenazine
02/2013
02/27/2013CN102947301A Quinolizidine and indolizidine derivatives
02/21/2013US20130045480 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules
02/20/2013CN102936246A Method for synthesizing tetrabenazine
02/20/2013CN102086197B Protoberberine derivative with insulin-sensitizing activity and application thereof
02/14/2013WO2013020229A1 Tetrahydroprotoberbine compounds and uses thereof in the treatment of neurological, psychiatric and neurodegenerative diseases
02/14/2013US20130040959 Heterocyclic Quinolizine Derived M1 Receptor Positive Allosteric Modulators
01/2013
01/22/2013US8357697 Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto
01/22/2013US8357686 Aryl-substituted polycyclic amines, method for the production thereof, and use thereof as a medicament
01/17/2013US20130018191 Process for the preparation of pyrido [2,1-a] isoquinoline derivatives comprising optical resolution of an enamine
01/16/2013EP2545991A1 Gold polymer nano-structure-supported scandium catalyst and use of the same
01/16/2013CN102875546A Second-order nonlinear optical chromophore having D-pi-A structure and treating julolidine derivative as donor, and synthetic method and use thereof
01/16/2013CN102875545A Novel preparation method of palmatine
01/02/2013CN102850346A Berberrubine 12-site derivatives as well as preparation method and applications thereof
12/2012
12/25/2012US8338449 Isoquinolinone potassium channel inhibitors
12/20/2012US20120321726 Berberine-containing pharmaceutical composition for inhibiting cancer stem cell growth or carcinoma metastasis and application thereof
12/19/2012CN102827159A Preparation method of jatrorrhizine
12/19/2012CN102827158A Preparation method of jatrorrhizine
12/13/2012WO2012168368A1 Benzoquinolizidine derivatives, method for preparing same, and therapeutic uses thereof
12/12/2012CN102040604B Fibriuretinin synthesis method
12/06/2012WO2012163179A1 Hexahydrodibenzo[a,g]quinolizine compound, preparation method therefor, pharmaceutical composition and use thereof
12/05/2012CN102807565A Improved method for extracting berberine
11/2012
11/29/2012WO2012162175A1 Emetine derivatives, prodrugs containing same, and methods of treating conditions using same
11/29/2012CA2836915A1 Emetine derivatives, prodrugs containing same, and methods of treating conditions using same
11/28/2012CN102796096A Hexahydro dibenzo [a,g] quinolizidine compound and preparation method, medicinal composition and application thereof
11/28/2012CN102150670B Application of phenanthroindolizidine and phenanthroquinolizidine derivatives and salts thereof in pesticides
11/28/2012CN102060853B Method for separating alkaloid by reversely two-way eluted pH-zone-refining counter-current chromatography
11/21/2012CN102786518A Palmatine hydrochloride crystal B substance, its preparation method, and its applications in medicines and healthcare products
11/21/2012CN102786482A Akt蛋白激酶抑制剂 Akt protein kinase inhibitor
11/21/2012CN102786472A Method for extraction separation of huperzine A in all-grass of snake foot clubmoss and its hairy root by supercritical extraction-crystallization technology
11/14/2012EP2522670A1 Heterocyclic CRF receptor antagonists
11/14/2012CN101619062B Natural fibrauretine crystal and macroporous adsorbent resin preparation method thereof
11/08/2012US20120283220 Antofine and cryptopleurine derivatives as anticancer agents
10/2012
10/26/2012WO2012143526A1 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof
10/26/2012CA2833648A1 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof
10/24/2012CN102746292A Cyclized berberine derivatives, preparation method and uses thereof
10/24/2012CN102746291A 13-substituted berberine derivatives and preparation method thereof, and uses of 13-substituted berberine derivatives as anti-tuberculosis drugs
10/16/2012US8288409 Quinolizidinone M1 receptor positive allosteric modulators
10/10/2012CN102285984B Preparation method of (2R, 3R, 11bR)-dihydrotetrabenazine and relevant compounds
10/03/2012CN102702190A Berberine electrostatic composite and preparation method of berberine electrostatic composite
10/03/2012CN102702189A Application of silica gel in purifying process of tetrahydro berberrubine
10/03/2012CN102702188A Method for extracting 2, 7-dihydroxyapogeissoschizine
10/03/2012CN101812061B Method for producing tetrahydroberineper from berberine hydrochloride
10/02/2012US8278453 Quinolizidinone M1 receptor positive allosteric modulators
10/02/2012US8278323 Opioid antagonists
09/2012
09/13/2012US20120232273 Process for the preparation of a dpp-iv inhibitor
09/13/2012US20120232076 Quinolizidinone carboxamide m1 receptor positive allosteric modulators
09/13/2012US20120232071 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds
09/12/2012CN102659777A Antitumor medicament
09/12/2012CN102285982B Method for separating and purifying monomer compounds from Chinese medicinal herb rhizoma coptidis
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