Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
02/1999
02/11/1999WO1999006394A1 Substituted 2-(benzoaryl)pyridines
02/11/1999WO1999006376A1 Novel sulphonamide derived from substituted anilines useful as medicines
02/11/1999WO1999006041A1 SUBSTITUTED ALKANOHYDROXAMIC ACIDS AND METHOD OF REDUCING TNFα LEVELS
02/11/1999CA2297894A1 Pyrrolidine-3-carboxylic acid derivatives and their use as endothelin antagonists
02/11/1999CA2296282A1 Substituted 2-(benzoaryl)pyridines
02/11/1999CA2295295A1 Substituted alkanohydroxamic acids and method of reducing tnf.alpha. levels
02/10/1999EP0895475A1 Vitronectin receptor antagonists
02/10/1999CN1207734A Metalloproteinase inhibitors, pharmaceutical compositions contg. them and their pharmaceutical uses, and methods and intermediates useful for their preparation
02/10/1999CN1207727A Substd. aryl or heteroarylamides having retinoid-like biological activity
02/10/1999CN1207291A Use of substituted 2,4-imidazolidinedione compounds as analgesics
02/10/1999CN1042033C Process for preparation of azithromycin dihydrochloride
02/09/1999US5869680 Reacting a oxazolidine derivative with protected hydroxy-taxol; decyclization and amination
02/09/1999US5869670 7-(4-aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
02/09/1999US5869663 Intermediates for neurokinin receptor antagonists
02/09/1999US5869659 Microbiocides
02/09/1999US5869655 Diamine compounds, methods of making same, method of use of same and intermediates
02/09/1999US5869516 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones
02/09/1999US5869511 Isoxazoline compounds as inhibitors of TNF release
02/09/1999US5869509 Treat disorders responsive to openers of the large conductance calcium-activated potassium channels
02/09/1999US5869495 Treatment and/or prophylaxis of hyperglycaemia
02/09/1999US5869481 Treating epileptic disorders
02/09/1999US5869455 Serine protease inhibitors-N-substituted derivatives
02/04/1999WO1999005139A1 2-[pyrazolyl and triazolyl-3'-oxymethylene]-phenyl-isoxazolones, triazolones and tetrazolones as pesticides and fungicides
02/04/1999WO1999005138A1 Heterocyclic compounds and antitumor agent containing the same as active ingredient
02/04/1999WO1999005132A1 Benzothia(oxa)diazol derivatives and their use as endothelin-receptor antagonists
02/04/1999WO1999005104A1 Indole compounds as cox-2 inhibitors
02/04/1999WO1999004794A1 Cyclic amine modulators of chemokine receptor activity
02/04/1999WO1999004780A1 Therapeutic or prophylactic agent for glomerulopathy
02/04/1999CA2297315A1 Endothelin receptor antagonists
02/04/1999CA2296729A1 2-[pyrazolyl and triazolyl-3'-oxymethylene]-phenyl-isoxazolones, triazolones and tetrazolones as pesticides and fungicides
02/04/1999CA2296314A1 Cyclic amine modulators of chemokine receptor activity
02/03/1999EP0894796A1 Imidazolines substituted with a heterocyclic ring as alpha-2 antagonists
02/03/1999EP0894795A1 Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them
02/03/1999EP0894792A1 Heterocycle-substituted benzene derivatives and herbicides
02/03/1999EP0894497A1 Use of substituted imidazolidin-2,4-diones as analgesics
02/03/1999EP0894088A1 Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl]-azaheterocyclamide compounds
02/03/1999EP0893995A1 Anticachectic composition
02/03/1999CN1207099A Substituted sulphonylamino (thio) carbonyl compounds as herbicides
02/03/1999CN1207092A Biphenyl ether oxazolines and their use as pest-control agents
02/03/1999CN1206712A Heterocyclic compound, preparation process thereof and medicinal composition containing same
02/03/1999CN1041919C N-(3-piperidinylcarbonyl)-beta-alanine derivatives as PAF antagonists
02/02/1999US5866593 Potent and selective phosphodiesterase type iv inhibitors, useful in the prophylaxis and treatment of diseases such as asthma where an unwanted inflammatory response or muscular spasm is present.
02/02/1999US5866572 Receptor tyrosine kinase inhibitory properties, treatment of proliferative diseases such as cancer.
02/02/1999US5866568 Heterocyclic compounds
01/1999
01/31/1999CA2244200A1 Use of substituted 2,4-imidazolidinedione compounds as analgesics
01/30/1999CA2244438A1 New benzimidazole, benzoxazole and benzothiazole derivatives, their preparation process and the pharmaceutical compositions containing them
01/30/1999CA2244435A1 New heterocyclic compounds, their preparation process and the pharmaceutical compounds containing them
01/28/1999WO1999003856A1 4-benzoyl-isoxazole- and -pyrazole derivatives and 2-cyano 1,3-dione derivatives as herbicides
01/28/1999WO1999003847A1 Process of production of 4-substituted-3-halogeno-1,4-benzoxazepine derivative and salts thereof
01/28/1999WO1999003846A1 Tricyclically substituted oxazolidinones
01/28/1999WO1999003833A1 Piperazine derivatives
01/28/1999DE19731571A1 Endothelin-Rezeptor-Antagonisten Endothelin receptor antagonists
01/28/1999DE19731153A1 2-(Pyrazolyl- und Triazolyl-3'-oxymethylen)-phenyl-isoxazolone und -triazolone, Verfahren zu ihrer Herstellung und ihre Verwendung 2- (pyrazolyl and triazolyl-3'-oxymethylene) phenyl-isoxazolones and -triazolone, processes for their preparation and their use
01/28/1999DE19730847A1 Tricyclisch substituierte Oxazolidinone Tricyclic substituted oxazolidinones
01/27/1999EP0892797A1 Inhibitors of farnesyl protein transferase
01/27/1999EP0892795A1 Piperidinylpyramidine derivatives
01/27/1999EP0892792A1 Process to prepare oxazolidinones
01/27/1999CN1206417A 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
01/27/1999CN1206414A N-acyl-2-substituted-4-(benzimidazolyl-or imidazopyridinyl-substituted pesidues)-piperidines as tachykinin antagonists
01/27/1999CN1206412A Method for selective protection of baccation derivatives and its application to taxane synthesis
01/27/1999CN1206410A Azolyl piperazinyl phenyl oxazolidinone antimicrobials
01/26/1999US5863935 Synthesis of indole derivatives of heterocyclic compounds for treatment of headaches and migraines
01/26/1999US5863924 5ht2b antagonist
01/26/1999US5863917 Anxiolytic agent, anticonvulsants, analgesics and neuroprotectives.
01/26/1999US5863753 Fluorescent stains for nucleic acids
01/26/1999CA2166901C 3-amidopyrazole derivatives, process for preparing these and pharmaceutical compositions containing them
01/21/1999WO1999002525A1 Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agents
01/21/1999WO1999002507A1 Isoxazole compounds, process for the preparation thereof, and insecticides and acaricides
01/21/1999WO1999002505A1 Il-5 inhibiting 6-azauracil derivatives
01/21/1999WO1999002503A1 Triazole compounds and the use thereof as dopamine-d3-ligands
01/21/1999WO1999002497A2 Pyridine derivatives
01/21/1999WO1999002155A1 Imidazole derivatives as mdr modulators
01/21/1999CA2296102A1 Triazole compounds and the use thereof as dopamine-d3-ligands
01/21/1999CA2294293A1 Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agents
01/21/1999CA2294145A1 Il-5 inhibiting 6-azauracil derivatives
01/20/1999EP0891972A1 3-(isoxazol-5-yl)-substituted benzoic acid derivatives and process for producing the same
01/20/1999EP0891361A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891359A1 Novel oxazolidine derivatives, process for their production and medicaments containing them
01/20/1999EP0891358A1 Oxazolidin-2-one derivatives, preparation method therefor and therapeutical use thereof
01/20/1999EP0891357A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891356A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891355A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891351A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891343A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891341A1 1,3,4-oxadiazine derivatives and their use as pesticides
01/20/1999EP0891340A1 Oxazole derivatives, their production and use
01/20/1999EP0891339A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891336A1 Substituted 1-methyl-3-benzyluracils
01/20/1999EP0891334A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0891333A1 Inhibitors of farnesyl-protein transferase
01/20/1999EP0790986B1 Aniline derivatives
01/20/1999EP0707579B1 Piperidinyl substituted methanoanthracenes as d1/d2-antagonists and 5ht2-serotanin-antagonists
01/20/1999CN1205699A 1-(1,2-disubstituted piperidinyl)-4-substituted piperazine derivatives
01/20/1999CN1205694A Quinazoline derivatives
01/20/1999CN1205328A Sulfonylaminocarboxylic acids
01/20/1999CN1041731C Pyrido [1,2,3-d,3)(1,3,4) benzoxadiazine derivatives
01/19/1999US5861515 Esterification of protected baccatin iii or 10-deacetylbaccatin iii using a carboxylic acid substituted oxazolidine, then deprotecting and acylation
01/19/1999US5861512 Reaction of 2-tert-butylcarboxamidepiperazine with acid in solvent, heating, dissolving, cooling, precipitation of crystals
01/19/1999US5861510 Antiarthritic agents, antiulcer agents, restenosis, oral diseases
01/19/1999US5861428 Alleviation of osteoarthritis, rheumatoid arthritis, septic arthritis, periodontal disease, corneal ulceration, proteinuria, aneurysmal aortic disease, dystrophobic epidermolysis bullosa, inflammation, osteopenias, tempero