Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
01/2005
01/12/2005EP1495001A1 Antibacterial agents
01/12/2005EP1494989A2 Compounds that modulate ppar activity and methods for their preparation
01/12/2005EP1494671A1 1-(4-piperidinyl)benzimidazolones as histamine h3 antagonists
01/12/2005EP1494668A2 Use of benzimidazole analogs in the treatment of cell proliferation
01/12/2005EP1494666A1 Orally deliverable pharmaceutical composition comprising an active compound having an aminosulfonyl group (cox-2 inhibitor), a polyethylene glycol and a free-radical scavenging antioxidant
01/12/2005EP1494663A1 Derivatives of 1-(oxoaminoacetyl) pentylcarbamate as cathepsin k inhibitors for the treatment of bone loss
01/12/2005EP1434773A4 Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
01/12/2005EP1299383B1 Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders
01/12/2005EP1183254B1 Substituted bicyclic heteroaryl compounds as integrin antagonists
01/12/2005EP1171423B1 Carbamic acid derivatives and their use as metabotropic glutamate receptor ligands
01/12/2005CN1564820A Heterocyclic compounds for use in the treatment of disorders of the urinary tract
01/12/2005CN1564687A Use of phosphodiesterase IV inhibitors
01/12/2005CN1564685A Pyrrolidinone derivatives
01/12/2005CN1562986A Precursor of key intermediate of AG 7088 class compound and its sythetic process
01/11/2005US6841685 Methods for making bis-heterocyclic alkaloids
01/11/2005US6841684 Imidiazoles having reduced side effects
01/11/2005US6841682 Prevent binding of adrenergenic receptors
01/11/2005US6841674 N-heterocyclic derivatives as NOS inhibitors
01/11/2005US6841673 Enzyme inhibitors; antiinflammatory agents; rheumatic diseases; antidiabetic agents
01/11/2005US6841571 Compounds useful as reversible inhibitors of cysteine proteases
01/11/2005US6841560 Substituted isoquinoline derivatives and their use as anticonvulsants
01/11/2005US6841550 Benzoxazine and benzothiazine derivatives and their use in medicines
01/11/2005CA2269128C Piperazino derivatives as neurokinin antagonists
01/11/2005CA2104909C Decahydroisoquinolines as excitatory amino acid receptor antagonists
01/11/2005CA2100924C Oxadiazine derivatives
01/06/2005WO2005000852A2 Product containing at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent
01/06/2005WO2005000841A1 Preparation of n2-alkylated 1,2,3-triazoles
01/06/2005WO2005000840A1 Substituted diketopiperazines and their use as oxytocin antagonists
01/06/2005WO2005000839A1 Process for producing 3-acylaminobenzofuran-2-carboxylic acid derivative
01/06/2005WO2005000821A1 Tachykinin receptor antagonists
01/06/2005WO2005000818A1 5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
01/06/2005WO2005000404A2 Heterocyclic compounds for preventing and treating disorders associated with excessive bone loss
01/06/2005WO2004101528A3 Isoquinoline derivatives and their use as gfat inhibitors
01/06/2005WO2004089947A3 Novel compounds having an antibacterial activity
01/06/2005WO2004087646A3 Pyrrolidino-1,2-dicarboxy-1-(phenylamide)-2-(4-(3-oxo-morpholino-4-yl)-phenylamide) derivatives and related compounds for use as inhibitors of coagulation factor xa in the treatment of thrombo-embolic diseases
01/06/2005WO2004037166A3 Therapeutic guanidines
01/06/2005WO2003042177A8 Piperidine derivatives and their use as modulators of chemokine receptor activity (especially ccr5)
01/06/2005US20050004368 N-heteroarylnicotinamide derivatives
01/06/2005US20050004360 Compounds and methods for modulation of estrogen receptors
01/06/2005US20050004207 Substituted isoindoles and the use thereof
01/06/2005US20050004204 2-Iminopyrrolidine derivatives
01/06/2005US20050004197 Thrombin receptors antagonists; oral efficacy
01/06/2005US20050004188 cytotoxic secondary metabolites; selective towards cancer cells magnesium ion binders
01/06/2005US20050004186 Phenyl-(2-[1,3,4]thiadiazol-2-yl-phenyl)-amine and (2-[1,3,4]Oxadiazol-2-yl-phenyl)phenyl-amine derivatives; immunomodulators; inflammation, proliferative diseases
01/06/2005US20050004180 Conditions mediated by beta chemokine receptor 2, monocyte chemotactic protein 1 and/or their interaction; such as 4-acetyl-5-cyclohexyl-3-amino-1-(4-methylphenyl)-1,5-dihydro-2H-pyrrol-2-one
01/06/2005US20050004176 Pyrazole-amide compounds useful as kinase inhibitors
01/06/2005US20050004175 Xanthine oxidase inhibitors; hyperuricemia and gout; such as 3-(4-isobutoxy-3-nitrophenyl)-5-(2-methyl-4-pyridyl)-1,2,4-triazole
01/06/2005US20050004174 Antibacterial agents
01/06/2005US20050004170 Substituted 4-phenyl-4-[1h-imidazol-2-yl]-piperidine derivatives for reducing ischaemic damage
01/06/2005US20050004140 Such as n-(4-fluorobenzyl)-6-(4-methyl-1H-imidazol-1-yl)pyrazin-2-amine; protein kinase associated disease states
01/06/2005US20050004136 Novel amidoalkyl-piperidine and amidoalkyl-piperazine derivatives useful as neurokinin receptor modulators
01/06/2005US20050004133 Inhibiting ligand gated ion channel vanilloid receptor (VR1); pain relievers; such as 6-(3,4-dichloro-phenyl)-N-(2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-nicotinamide
01/06/2005US20050004110 Inhibitors of glycogen synthase kinase-3 (gsk-3) and aurora-2, both serine/threonine protein kinases; for treating diseases such as cancer, diabetes and alzheimer's disease
01/06/2005US20050004097 Indole derivatives
01/06/2005US20050004096 Indole derivatives, process for producing the same and drugs containing the same as the active ingredient
01/06/2005CA2672071A1 Process for preparing 3-acylaminobenzofuran-2-carboxylic acid derivative
01/06/2005CA2530668A1 Product containing at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent
01/06/2005CA2530662A1 Benzothiazole-4,7-diones and benzoxazole-4,7-diones with substituents in position 5 or 6 and method for production thereof
01/06/2005CA2530377A1 Process for preparing 3-acylaminobenzofuran-2-carboxylic acid derivative
01/06/2005CA2529109A1 Preparation of n2-alkylated 1,2,3-triazoles
01/06/2005CA2528619A1 Diphenylpyridine derivatives, preparation and therapeutic application thereof
01/06/2005CA2527079A1 Heterocyclic compounds for preventing and treating disorders associated with excessive bone loss
01/06/2005CA2526487A1 Heterocyclic methyl sulfone derivative
01/05/2005EP1493757A1 Photopolymerizable composition
01/05/2005EP1493743A1 Substituted bipiperidine intermediates and derivatives thereof
01/05/2005EP1492795A1 1- or 3-thia-benzonaphthoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
01/05/2005EP1492788A1 Indole-amid derivatives which possess glycogen phosphorylase inhibitory activity
01/05/2005EP1492785A1 New compounds
01/05/2005EP1492765A2 Novel gamma secretase inhibitors
01/05/2005EP1492763A1 Carboxamidine derivatives and their use in the treatment of vascular diseases
01/05/2005EP1492756A1 Novel thyroid receptor ligands
01/05/2005EP1492571A2 Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
01/05/2005EP1492537A1 Morpholine derivatives with a substituted acetamide group in the 2-position for use as ccr-3 antagonists for the treatment of inflammatory diseases
01/05/2005EP1492536A1 4-(n-phenylamino)-quinazolines / quinolines as tyrosine kinase inhibitors
01/05/2005EP1492533A1 N-substituted pyridinone and pyrimidinone derivatives for use as lp-pla2 inhibitors in the treatment of artherosclerosis
01/05/2005EP1492528A1 Antidiabetic agents
01/05/2005EP1492487A2 Mitotic kinesin inhibitors
01/05/2005EP1226126B1 Pyrimidine derivatives
01/05/2005EP1027051B1 Antithrombotic agents
01/05/2005DE10328036A1 New N-benzyl-anthranilic acid (hetero)arylamide derivatives and analogs, are tyrosine kinase KDR and FLT inhibitors and angiogenesis inhibitors, useful e.g. for treating tumors, psoriasis or restenosis
01/05/2005DE10327428A1 Preparation of pyrrolidine-1,2-dicarboxanilide derivatives for use as factor Xa inhibiting antithrombotic agents, comprises reacting pyrrolidine-2-carboxylic acid with phenyl isocyanate then aniline derivative
01/05/2005CN1561340A Novel 1, 2, 4-triazole compound
01/05/2005CN1561338A Chroman derivatives as 5-hydroxytryptamine-6 ligands
01/05/2005CN1561337A Stereospecific process for the synthesis of 2-yl chroman derivatives
01/05/2005CN1561212A Benzimidazolidinone derivatives as muscarinic agents
01/05/2005CN1561211A Nociceptin analogs
01/05/2005CN1183156C Heterocyclic compounds, intermediates thereof and elastase inhibitors
01/05/2005CN1183129C Condensed azepines as vasporession agonists
01/05/2005CN1183116C Substituted isoquinoline derivatives and pharmaceutical composition containing them, its preparation method and use
01/05/2005CN1183113C Tri-aryl acid derivatives as PPAR receptor ligands
01/04/2005US6838564 Substituted pyridine herbicides
01/04/2005US6838483 Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same
01/04/2005US6838466 Compounds for the treatment of inflammatory disorders
01/04/2005US6838464 Inhibitor of cyclin-dependent kinase
01/04/2005US6838453 Therapy for osteoporosis
01/04/2005US6838416 Herbicidal 5-benzyloxymethyl-1,2-isoxazoline derivatives
01/04/2005US6838415 Substituted benzoylisoxazoles and the use thereof as herbicides
01/04/2005CA2350854C 1,4-dihydropyridine derivatives and methods of producing the same
01/04/2005CA2293834C Substituted naphthopyrans
01/04/2005CA2106897C Use of substituted 1,2,4-oxadiazole derivatives for combating endoparasites, new substituted 1,2,4-oxadiazole derivatives, and processes for their preparation