Patents
Patents for C07D 413 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms (64,687)
06/2005
06/08/2005EP1537096A2 Derivatives of dioxane-2-alkyl carbamates, preparation method thereof and application of same in therapeutics
06/08/2005EP1537087A1 Novel aminoindazole derivatives as medicines and pharmaceutical compositions containing same
06/08/2005EP1537084A1 Substituted 2-alkylamine nicotinic amide derivatives and use there of
06/08/2005EP1537081A1 Dihydropyridine derivatives for use as human neutrophil elastase inhibitors
06/08/2005EP1537078A1 Indoles having anti-diabetic activity
06/08/2005EP1537072A1 Substituted aminoethers for the treatment of alzheimer s disease
06/08/2005EP1536797A1 1-amido-4-phenyl-4-benzyloxymethyl-piperidine derivatives and related comounds as neurokinin-1 (nk-1) antagonsists for the treatment of emesis, depression, anxiety and cough
06/08/2005EP1536790A2 Oxadiazoles as modulators of metabotropic glutamate receptor-5
06/08/2005EP1536784A1 Hetero biaryl derivatives as matrix metalloproteinase inhibitors
06/08/2005EP1465854A4 Chalcone derivatives and their use to treat diseases
06/08/2005EP1373231B1 3-heterocyclyl-propano-hydroxamic acid as pcp inhibitors
06/08/2005EP1370528B1 Mch antagonists and their use in the treatment of obesity
06/08/2005EP1337526B1 Substituted imidazoles useful in the treatment of inflammatory diseases
06/08/2005EP1294710B1 Indole derivatives useful for the treatment of cns disorders
06/08/2005EP1189895B1 Thiazole and oxazole derivatives and their pharmaceutical use
06/08/2005EP1089735B1 4-benzyl piperidine alkylsulfoxide heterocycles and their use as subtype-selective nmda receptor antagonists
06/08/2005CN1625410A 2, 4, 6-triamino-1, 3, 5-triazine derivative
06/08/2005CN1625400A 2, 4-pyrimidinediamine compounds and their uses
06/08/2005CN1623992A Novel medicine of non peptide like angiotensin II receptor antagonism agent, their preparation and application
06/08/2005CN1623991A Substituded acza nember 5/nember 6 ring compound and its preparation process
06/08/2005CN1623984A Fused-ring compounds and use thereof as drugs
06/08/2005CN1623537A Biaryl sulfonamides and its using method
06/08/2005CN1205213C Method for the production of imidazol-[1,2-c][2,3]-benzodiazepines and intermediates in production thereof
06/08/2005CN1205194C Biphenyl ether oxazolines and their use as pest-control agents
06/08/2005CN1205185C Nitrogenous cyclic compounds and pharmaceutical compositions containing the same
06/08/2005CN1205183C New amidino derivatives and their use as thrombin inhibitors
06/08/2005CN1204889C Adhesion receptor antagonists
06/07/2005US6903128 Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases
06/07/2005US6903125 Tetrahydro-2H-thiopyran-4-carboxamide derivative
06/07/2005US6903117 Indole derivatives for the treatment of osteoporosis
06/07/2005US6903115 Bipiperidine compounds
06/07/2005US6903109 Arylindenopyridines and related therapeutic and prophylactic methods
06/07/2005US6903103 Linear cyclic ureas
06/07/2005US6903095 Phthalimido derivatives and a process for their preparation
06/07/2005US6903094 As analgesic
06/07/2005US6903088 Compounds which inhibit leukocyte adhesion mediated by VLA-4
06/07/2005US6903085 Substituted piperidine compounds useful as modulators of chemokine receptor activity
06/07/2005CA2299036C 4-phenyl-4-heteroarylpiperidine derivatives
06/07/2005CA2281090C Sulfonamide compounds and salts for treatment of endothelin-mediated disorders
06/07/2005CA2186039C New oral pharmaceutical dosage form
06/02/2005WO2005049608A1 Quinolonecarboxylic acid compounds having 5-ht4 receptor agonistic activity
06/02/2005WO2005049605A1 Antibacterial aminoquinazolidinedione derivatives
06/02/2005WO2005049594A1 N-acylsulfonamide apoptosis promoters
06/02/2005WO2005049593A2 N-acylsulfonamide apoptosis promoters
06/02/2005WO2005049589A2 Heterocyclic compounds for the treatment of hyperlipidemia, diabetes, obesity and similar diseases
06/02/2005WO2005049581A1 Pyridazin-3 (2h) -one derivatives and their use as pde4 inhibitors
06/02/2005WO2005049579A2 Immobilized n-substituted tricyclic 3-aminopyrazoles for the identification of biomolecular targets
06/02/2005WO2005049570A1 Method for synthesising optically active piperidines by the hydrogenation of optically active pyridines
06/02/2005WO2005049563A2 Efficient nucleotide synthesis
06/02/2005WO2005049559A2 Novel piperidine-substituted indoles- or hetero-derivatives thereof and their use as modulators of chemokine receptor (ccr-3)
06/02/2005WO2005049064A1 Drug therapy for celiac sprue
06/02/2005WO2005048953A2 Amide derivatives as kinase modulators
06/02/2005WO2005048948A2 Urea derivatives as kinase modulators
06/02/2005WO2005048922A2 Sulfonylaminovalerolactams and derivatives thereof as factor xa inhibitors
06/02/2005WO2005027823A3 3-heterocyclyl-indole derivatives as inhibitors of glycogen synthase kinase-3 (gsk-3)
06/02/2005WO2005016879A3 Cyclic pyrazinoylguanidine sodium channel blockers
06/02/2005WO2005009950A3 Piperidine derivatives as melanocortin-4 receptor agonists
06/02/2005WO2005005380A3 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
06/02/2005US20050119489 Antidiabetic, anorexigenic, hypotensive, and anticholesterol agents that are synergistically combined with other active agents; obesity, premenstrual tension, hyperlipidemia, myocardial infarction and skin disorders
06/02/2005US20050119484 Mitotic kinesin inhibitors
06/02/2005US20050119468 preparing azithromycin using a crystalline 9-deoxo-9a-aza-9a-homoerythromycin A hydrate as an intermediate, and a novel precursor thereof, crystalline 9-deoxo-9a-aza-9a-homoerythromycin A hydrate
06/02/2005US20050119332 Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
06/02/2005US20050119322 Phorboxazole derivatives for treating cancer
06/02/2005US20050119317 such as (5RS)-3-(3-Fluoro-4-thiomorpholin-4-yl phenyl)-5-(1,2,3-triazol-1-ylmethyl)-4,5-dihydroisoxazole; antibiotics
06/02/2005US20050119312 Lipid lowering agents; hypotensive agents; obesity
06/02/2005US20050119311 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
06/02/2005US20050119292 antibiotic; Gram-positive pathogens (Staphylococci, Enterococci, and Streptococci ), MRSA and MRCNS; resistance to vancomycin and E. faecium to both aminoglycosides and beta--lactams; gram negative strains H.influenzae, M.catarrhalis and chlamydia; improved activity against mono-amine oxidase (MAO)
06/02/2005US20050119271 Pyrimidine A2B selective antagonist compounds, their synthesis and use
06/02/2005US20050119260 5-(7-Chloro-1-methyl-1H-indol-3-ylmethyl)-3-methyl-imidazolidine-2,4-dione; neurodegenerative and necrotic cell disease; non-apoptotic/caspase-independent cell death mechanisms; ischemia, stroke, cardiac infarction, infection and sepsis
06/02/2005US20050119256 Aromatic amino acid derivates and medicinal compositions
06/02/2005US20050119252 Ligands of melanocortin receptors and compositions and methods related thereto
06/02/2005US20050119250 Amino-derivatives as novel inhibitors of histone deacetylase
06/02/2005US20050119231 Quinolone antibiotics such as 3-Amino-1-cyclopropyl-6-fluoro-7-(3-hydroxymethyl-pyrrolidin-1-yl)-8-methoxy-1H-quinazoline-2,4-dione, used for treating gramnegative or grampositive bacterial infection in mammals
06/02/2005US20050119227 Cyclic amine bace-1 inhibitors having a benzamide substituent
06/02/2005DE10335545A1 New bicyclic nitrogen-containing heteroaryl-substituted amides, are inhibitors of Factor Xa and/or related serine proteases, useful as antithrombotic agents, e.g. for treating or preventing deep leg vein thrombosis
06/02/2005CA2546339A1 Antibacterial aminoquinazolidinedione derivatives
06/02/2005CA2545711A1 Urea derivatives as kinase modulators
06/02/2005CA2545261A1 Piperidine-substituted indoles- or heteroderivatives thereof
06/02/2005CA2545193A1 Pyridazin-3 (2h) -one derivatives and their use as pde4 inhibitors
06/01/2005EP1535967A1 Oxazine derivatives
06/01/2005EP1535915A1 Furan or thiophene derivative and medicinal use thereof
06/01/2005EP1535909A2 Cyclic amine derivatives and their use as drugs
06/01/2005EP1535906A1 Nitrogen-containing compounds
06/01/2005EP1534705A1 Process for preparing zolmitriptan compounds
06/01/2005EP1534703A2 Antagonists of melanin concentrating hormone receptor
06/01/2005EP1534700A1 Novel thiophene derivatives, preparation method thereof and pharmaceutical compositions containing same
06/01/2005EP1534696A1 Therapeutic compounds for treating dyslipidemic conditions
06/01/2005EP1534695A2 Tyrosine kinase inhibitors
06/01/2005EP1534694A1 Aryl and heteroaryl morpholine derivatives
06/01/2005EP1534693A2 1, 3-diamino-2-hydroxypropane prodrug derivatives
06/01/2005EP1534685A1 1h-indazole-3-carboxamide compounds as cyclin dependent kinases (cdk) inhibitors
06/01/2005EP1534676A1 Piperidinetriol derivatives as inhibitors of glycosylceramide synthase
06/01/2005EP1534391A1 Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders
06/01/2005EP1534280A1 Aryl piperidine derivatives and use thereof to reduce elevated levels of ldl-cholesterol
06/01/2005EP1534275A1 Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals
06/01/2005EP1404330B1 Substituted 8-arylquinoline pde4 inhibitors
06/01/2005EP1351959B1 Novel pleuromutilin derivatives
06/01/2005EP1268465B1 Triarylimidazole derivatives as cytokine inhibitors
06/01/2005EP1254136A4 FACTOR Xa INHIBITORS WITH ARYL-AMIDINES AND DERIVATIVES, AND PRODRUGS THEREOF
06/01/2005EP1248761A4 Compounds which mimic the chemical and biological properties of discodermolide