Patents
Patents for C07D 405 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom (69,397)
03/2009
03/04/2009EP2029576A1 Cyclohexylimidazole lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
03/04/2009EP2029572A2 Organic compounds
03/04/2009EP2029553A1 Substituted pyrazinone derivatives for use as a medicine
03/04/2009EP2029551A2 Pyridinone and pyridazinone derivatives as inhibitors of poly(adp-ribose)polymerase (parp)
03/04/2009EP2029543A2 Substituted 3-cyanopyridines as protein kinase inhibitors
03/04/2009EP2029540A2 Benzamide derivatives and uses related thereto
03/04/2009EP2029535A1 Isoindole derivatives useful for treating pain, gastrointestinal diseases and cancer
03/04/2009EP1836187B1 1h-indole-3-carboxylic acid derivatives and their use as ppar agonists
03/04/2009EP1485370B1 Amino-derivatives as novel inhibitors of histone deacetylase
03/04/2009EP1452527B1 Azabicyclo compound, matrix metalloprotease inhibitor, and skin preparation
03/04/2009EP1140908B1 Triazole compounds with dopamine-d3-receptor affinity
03/04/2009CN101379043A Substituted 2-Aminopyrimidine-4-ones, their pharmaceutical compositions and their use in the treatment and/or prevention of ass-related pathologies
03/04/2009CN101379034A Benzamide and heteroarene derivatives as CETP inhibitors
03/04/2009CN101378756A Piperidine derivatives as CXCR3 receptor antagonists
03/04/2009CN100465173C A selective kinase inhibitor
03/04/2009CN100465163C Cis-2,4,5-triaryl-imidazolines
03/03/2009US7498460 Isophthalic acid derivatives
03/03/2009US7498441 Melanin-concentrating hormone antagonists for eating disorder and diabetes treatment
03/03/2009US7498435 One amine is substituted with a fused heterocyclic ring and the other with a fused heterocyclic ring or phenyl ring, e.g., N2,N4-Bis(3,4-ethylenedioxyphenyl)-5-cyano-2,4-pyrimidinediamine; inhibit IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators such as histamine
03/03/2009US7498349 To treat Gram-positive bacterial infections; antibacterial and/or antifungal properties; Preferably drug-resistant strains of bacteria
03/03/2009US7498347 improved metabolic stability; gastrointestinal conditions like hypermotility, irritable bowel syndrome (IBS), constipation or diarrhea; amidation
03/03/2009US7498343 Mycobacterial inhibitors
03/03/2009US7498302 Analogues of rachelmycin and the duocarmycins that are potent cytotoxins containing a benzodipyrrole or naphthopyrrole ring; anticancer agents
02/2009
02/26/2009WO2009026407A1 Pyrrole compounds having sphingosine-1-phosphate receptor agonist or antagonist biological activity
02/26/2009WO2009026252A1 Methods for assaying alpha-l-iduronidase enzymatic activity
02/26/2009WO2009026204A1 2-heteroarylamino-pyrimidine derivatives as kinase inhibitors
02/26/2009WO2009025839A2 Phosphodiesterase 10 inhibitors
02/26/2009WO2009024819A1 Cannabinoid receptor ligands
02/26/2009WO2009024342A2 Novel microbiocides
02/26/2009WO2009024341A2 Condensed anthran i lami de derivatives as insectisides
02/26/2009WO2008140553A3 Mapk/erk kinase inhibitors
02/26/2009WO2008138551A3 3-(2-alkoxy-phenyl)-substituted tetramates
02/26/2009WO2007014226A3 Compounds for the treatment of neurodegeneration and stroke
02/26/2009US20090054650 Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids
02/26/2009US20090054630 Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
02/26/2009US20090054514 (3-Amino-6-phenyl-benzofuran-2-yl)-(2,4-dichloro-phenyl)-methanone; antiprolifrative, anticarcinogenic, antitumor agent; lymphomas, sarcomas, and leukemias
02/26/2009US20090054495 4-Chloro-2-phenylsulfanyl-phenyl)-4-isopropoxy-benzenesulfonamide; inflammatory bowl disease such as Crohn's disease or Colitis
02/26/2009US20090054488 Isomigrastatin Analogs In The Treatment Of Cancer
02/26/2009US20090054484 Substituted heteroaryl benzofuran acids
02/26/2009US20090054464 Hdac inhibitor
02/26/2009US20090054462 Hydroisoindoline tachykinin receptor antagonists
02/26/2009US20090054460 Piperazine derivatives and methods of use
02/26/2009US20090054459 Substituted indoles
02/26/2009US20090054440 Quinoline derivatives as neurokinin receptor antagonists
02/26/2009US20090054429 Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
02/26/2009US20090054420 Bicyclic-substituted amines as histamine-3 receptor ligands
02/26/2009US20090054397 Pyrazole compounds and pharmaceutical compositions comprising the compound
02/26/2009US20090054395 focal adhesion kinase inhibitor, i.e. FAK inhibitor; tyrosine kinase inhibitors; cancer, osteoporosis; e.g. N-methyl-4-({4-[({3-[methyl(methylsulfonyl)amino]pyrazin-2-yl}methyl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)benzamide hydrochloride
02/26/2009US20090054240 Heteroaroyl-substituted Alanines
02/26/2009CA2696697A1 Cannabinoid receptor ligands
02/26/2009CA2696429A1 Pyrrole compounds having sphingosine-1-phosphate receptor agonist or antagonist biological activity
02/25/2009EP2027107A1 2, 4 -diamino pyrimidines as cell cycle kinase inhibitors
02/25/2009EP2027104A1 Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors
02/25/2009EP2027098A1 1-(2-aryl-2-oxoethyl)-3-phenyl-1, 4-diazaspiro (4.5)dec-3-en-2-one derivatives and their use as glycine transporter inhibitors
02/25/2009EP1578726B1 Tetrahydroquinoline derivatives
02/25/2009EP1506188B1 Process for the preparation of a hydrate of an anthranilic acid derivative
02/25/2009EP1027056B1 Alpha-ketoamide multicatalytic protease inhibitors
02/25/2009CN101374833A Novel pyrone-indole derivatives and process for their preparation
02/25/2009CN101374832A Use of 4-imidazole derivatives for CNS disorders
02/25/2009CN101374831A Tetrahydropyrane antibiotics
02/25/2009CN101374828A Heterocyclylalkyl derivatives as novel inhibitors of histone deacetylase
02/25/2009CN101374818A Pyrimidine derivatives
02/25/2009CN101374817A Trisubstituted amine compound as inhibitors of cholesteryl ester transfer protein cetp
02/25/2009CN101374815A Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (HIF)
02/25/2009CN101374811A Novel dual nk2/nk3-antagonists, pharmaceutical compositions comprising them and processes for their preparations
02/25/2009CN101374808A Indole sulfonamide modulators of progesterone receptors
02/25/2009CN101374517A Use of 2-imidazoles for the treatment of CNS disorders
02/25/2009CN101374516A Use of substituted 2-imidazole of imidazoline derivatives
02/25/2009CN101372485A Preparation of triazole compounds
02/24/2009US7495110 Benzimidazole derivatives and their use as GnRH antagonists
02/24/2009US7495109 Nociceptin analogs
02/24/2009US7495104 Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors
02/24/2009US7495027 drugs that inhibit biosynthesis of bacterial cell walls, such as (5Z)-5-[(3',5'-dichloro-1,1'-biphenyl-3-yl)methylene]-3-(3,5-dichlorophenyl)-4-hydroxyfuran-2(5H)-one, used for treatment of bacterial infections, and as parasiticides
02/24/2009US7495017 3-(3-Cyclopentyloxy-4-methoxyphenyl)-1H-pyrazole;adenosine monophosphate activator; antiinflammatory agent, antidepressant, antiallergen, cognition activator, neurodegenerative diseases; arthritis, Alzheimer's disease, schizophrenia, Parkinson disease
02/24/2009US7495016 inhibiting HIV replication in a cell; inhibiting reverse transcriptase
02/24/2009US7495014 Gyrase inhibitors and uses thereof
02/24/2009US7494996 can be applied as sprays by methods commonly employed in crops such as vegetables, fruits, ornamentals, seeds, turf, cereal and vines among other plants
02/24/2009US7494990 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
02/24/2009CA2426221C New neurokinin antagonists, processes for preparing them and pharmaceutical compositions containing these compounds
02/19/2009WO2009022731A1 P2x4 receptor antagonist
02/19/2009WO2009022730A1 P2x4 receptor antagonist
02/19/2009WO2009022720A1 Five-membered heterocyclic compound
02/19/2009WO2009022171A1 Pyridinyiioxy pyridines as alk5 inhibitors
02/19/2009WO2008157404A3 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
02/19/2009WO2008154246A8 Hiv integrase inhibitors
02/19/2009WO2008152514A3 Process for the preparation of alfuzosin and salts thereof
02/19/2009WO2008130600A3 Quinolones and azaquinolones that inhibit prolyl hydroxylase
02/19/2009WO2008087514A3 Hdac inhibitors
02/19/2009WO2008079787A3 Glucokinase activators
02/19/2009WO2006065484A3 Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof
02/19/2009US20090048447 Method for decreasing opioid metabolism
02/19/2009US20090048429 aspartic acid aldehyde moieties via reduction, deprotecting, reacting with benzyloxycarbonyl-tert-leucine under coupling conditions, deprotection conditions to provide amine and reacting amine and 4-amino-3-chlorobenzoic; for preparing caspase inhibitors and/or prodrugs
02/19/2009US20090048337 Modulation of anxiety through blockade of anandamide hydrolysis
02/19/2009US20090048303 Indole-2-carboxamidine derivatives as nmda receptor antago
02/19/2009US20090048255 Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs
02/19/2009US20090048230 Compounds and compositions useful as cathepsin s inhibitors
02/19/2009US20090048227 Substituted-1-Phthalazinamines As Vr- 1 Antagonists
02/19/2009US20090048226 Inhibitors of caspases
02/19/2009US20090048224 Compounds and methods of use
02/19/2009US20090048190 Antiviral activity and resolution of 2-hydroxymethyl-5(5-fluorocytosin-1-yl)-1,3-oxathiolane