Patents
Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587)
09/1998
09/11/1998CA2282851A1 Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid
09/11/1998CA2282850A1 Preparation of phosphonium compounds as intermediates for glycine antagonists
09/11/1998CA2281518A1 4,4-difluoro-2,3,4,5-tetrahydro-1h-1-benzazepine derivatives and drug compositions containing them
09/11/1998CA2278547A1 Small molecules useful in the treatment of inflammatory disease
09/09/1998EP0862558A1 Substituted 4,5-di(trifluoromethyl)pyrazoles and their use as herbicides and for desiccating/defoliating plants
09/09/1998EP0862555A1 Substituted aryl or heteroarylamides having retinoid-like biological activity
09/09/1998EP0862552A1 Succinimide and maleimide cytokine inhibitors
09/09/1998EP0716649B1 5-arylindole derivatives
09/09/1998EP0715627B1 Indole derivatives as thromboxane a2 antagonists
09/09/1998EP0591280B1 Use of tetrahydrocarbazole derivatives as 5ht1-receptor agonists
09/09/1998EP0584085B1 Antibiotic carbapenem derivatives
09/09/1998CN1192735A Parasiticidal compound
09/09/1998CN1192697A Epoxy-steroidal aldosterone antagonist and angiotensin 2 antagonist combination therapy for treatment of congestive heart failure
09/09/1998CN1192696A Spironolactone and angiotensin 2 antagonist combination therapy for treatment of congestive heart failure
09/09/1998CN1192681A Novel medical use
09/09/1998CN1192356A Composition for oxidation dyeing of keratin fibres and dyeing process using this composition
09/09/1998CN1039714C Substituted indole derivatives, prepn. method and application thereof
09/08/1998US5804686 fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
09/08/1998US5804564 Antitumor indolopyrrolocarbazole derivatives
09/03/1998WO1998038188A1 Cycloimido-substituted benzofused heterocyclic herbicides
09/03/1998WO1998038171A1 Pyrimidine carboxylates and related compounds and methods for treating inflammatory conditions
09/03/1998WO1998038170A1 Substituted benzimidazoles and their use for treating retroviral infection
09/03/1998WO1998038167A1 Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of mip-1-alpha binding to its ccr1 receptor
09/03/1998WO1998037893A1 Dopamine d4 receptor antagonist
09/03/1998CA2282552A1 Substituted benzimidazoles and their use for treating retroviral infection
09/03/1998CA2281688A1 Cycloimido-substituted benzofused heterocyclic herbicides
09/02/1998EP0861246A1 Prolylendopeptidase inhibitors
09/02/1998EP0861243A1 Heterocyclic compounds as bradykinin antagonists
09/02/1998EP0861238A1 Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
09/02/1998EP0861233A1 N-protected/n-substituted-beta-amino hydroxy sulfonates
09/02/1998CN1192209A Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas
09/02/1998CN1192147A Imidazole compounds
09/02/1998CN1192144A 1H-4(5)-substituted imidazole derivatives
09/01/1998US5801180 Antiischemic agents and cardiovascular disorders
09/01/1998US5801150 Aminopyri(mi)dine derivatives combined with amino acids, and pharmacological activities thereof
09/01/1998CA2166903C 3-amidopyrazole derivatives, process for preparing these and pharmaceutical compositions containing them
08/1998
08/27/1998WO1998037087A1 Inhibition of major groove dna binding proteins by modified polyamides
08/27/1998WO1998037079A1 N-heterocyclic derivatives as nos inhibitors
08/27/1998WO1998037075A1 Disubstituted bicyclic heterocycles, their production and use as medicaments
08/27/1998WO1998037067A1 Design, synthesis and use of specific polyamide dna-binding ligands
08/27/1998WO1998037066A1 Improved polyamides for binding in the minor groove of double stranded dna
08/27/1998CA2281948A1 Inhibition of major groove dna binding proteins by modified polyamides
08/27/1998CA2281947A1 Improved polyamides for binding in the minor groove of double stranded dna
08/27/1998CA2281930A1 Design, synthesis and use of specific polyamide dna-binding ligands
08/26/1998EP0859771A1 Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
08/26/1998EP0859765A1 Pyrazin-2-one derivatives, their use, and intermediates for their production
08/26/1998EP0859759A1 Sulphonic acids and their use as u/v absorbers
08/26/1998CN1191533A 1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivs. as neurokinin receptor antagonists
08/25/1998US5798353 Treating eating disorder, obesity, diabetes, psychological disorder, sexual disorder, psychosis, memory disorder
08/25/1998US5798337 Low molecular weight peptidomimetic growth hormone secretagogues
08/25/1998US5798311 N-aryl-3-aryl-4-substituted-4,5-dihydro-1H-pyrazole-1-carboxamides and methods of their production
08/25/1998CA2071193C Sulfonamides
08/20/1998WO1998035960A1 Prolylendopeptidase inhibitors
08/20/1998WO1998035958A1 Phthalazines with angiogenesis inhibiting activity
08/20/1998WO1998035944A1 Amides as npy5 receptor antagonists
08/20/1998WO1998035941A1 New benzolactam derivatives and medicinal compositions containing the same
08/20/1998DE19706229A1 New aryl-substituted bi:cyclic heterocyclic compounds
08/20/1998CA2251580A1 Amides as npy5 receptor antagonists
08/19/1998EP0858999A1 Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
08/19/1998EP0858464A1 Thrombin inhibitors
08/19/1998EP0858451A1 Pharmaceutically active quinazoline compounds
08/19/1998EP0858444A1 Cyclopentyl tachykinin receptor antagonists
08/18/1998US5795907 Gastin and CCK receptor ligands
08/18/1998US5795899 Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl) pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)-amide, a process for the preparation thereof, the use thereof as pharmaceuticals and starting materials
08/18/1998US5795889 Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
08/18/1998US5795888 Analgesics, antiinflammatory agents, antidiabetic agents
08/18/1998US5795887 Method of inducing cholecystokinin agonist activity using 1,4- Benzodiazepine compounds
08/13/1998WO1998018466A3 Anti-neurogenic inflammatory compounds and compositions and methods of use thereof
08/12/1998EP0857483A1 Substituted aminopyridines in the treatment of glucose metabolism disorders
08/12/1998EP0857171A2 Imidazole derivatives and the use thereof as nitrogen monoxide synthase inhibitors
08/12/1998EP0857067A1 Radioprotectors
08/12/1998CN1190395A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) n-£(aminoiminomethyl) phenylalkyl|-azaheterocyclylamide compounds
08/12/1998CN1190392A 5-pyrazolylbenzoic acid derivatives as herbicides
08/12/1998CN1190390A Nitric oxide synthase inhibitors derived from cyclic amidines
08/11/1998US5792783 Capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation
08/11/1998US5792782 Treating cryptococcus neoformans
08/11/1998US5792781 Antifungal agents, processes for the preparation thereof, and intermediates
08/11/1998US5792778 2-substituted aryl pyrroles, compositions containing such compounds and methods of use
08/11/1998US5792768 Reduced side effects
08/11/1998US5792767 Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists
08/11/1998US5792766 Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
08/11/1998CA2009678C Pyridazinone, oxadiazinone, thiadiazinone and triazinone cardiotonic agents
08/06/1998WO1998033802A1 Quinazolinone compounds
08/06/1998WO1998033798A2 Pyrido[2,3-d]pyrimidines and 4-amino-pyrimidines as inhibitors of cell proliferation
08/06/1998WO1998016507A3 New heterocyclylmethyl-substituted pyrazol derivates and their use for treating cardiovascular diseases
08/06/1998CA2271157A1 Pyrido[2,3-d]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation
08/05/1998EP0856001A1 Pyrimidine derivatives as 5ht 2c?-receptor antagonists
08/05/1998EP0649407B1 Dimeric piperidine, tetrahydropyridine and piperazine derivatives
08/05/1998CN1189829A Piperazino derivatives as neurokinin antagonists
08/05/1998CN1189823A Cyclic amidino agents useful as nitric oxide synthase inhibitors
08/05/1998CN1189821A Substituted oximes, hydrazones and olefins as neurokinin antagonists
08/05/1998CN1189490A Process for preparing 1-biphenylmethylimidazole derivatives
08/04/1998US5789429 Antifungal agents, processes for the preparation thereof, and intermediates
08/04/1998US5789417 Anticarcinogenic agents
08/04/1998US5789410 Treatment of schizophrenia, depression, parkinson's disease
08/04/1998US5789404 Central nervous system disorders and antiserotonin agents
08/04/1998US5789402 Compounds having effects on serotonin-related systems
08/04/1998CA2161533C Indole derivatives
08/04/1998CA2132706C Acylaminoindole derivatives as 5-ht1 agonists
07/1998
07/30/1998WO1998032739A1 Pyrazole derivatives