Patents
Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587)
12/2003
12/03/2003CN1129597C Heterocyclic compounds and antitumor agent containing same as active ingredient
12/03/2003CN1129583C Compound as intermediates for use in preparation of optically active 2-imidazoline-5-one or 2-imidazoline-5-thionone derivatives
12/03/2003CN1129578C Tetrahydrobenzindole derivs
12/02/2003US6657060 Neuropeptide Y antagonists; treatment of eating disorders such as obesity and hyperphagia
12/02/2003US6656945 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-one cGMP-PDE inhibitors for the treatment of erectile dysfunction
12/02/2003US6656939 Pyrazole compounds useful as protein kinase inhibitors
12/02/2003US6656935 Aromatic nitrogen-containing 6-membered cyclic compounds
12/02/2003US6656933 Novel compounds which inhibit production of cytokines involved in inflammatory processes
11/2003
11/27/2003WO2003097649A2 1-oxa-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
11/27/2003WO2003097637A1 (imidazol-1-yl-methyl)-pyridazine as nmda receptor blocker
11/27/2003WO2003097610A1 Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
11/27/2003WO2003097609A1 N-substituted tricyclic 3-aminopyrazoles as pdfg receptor inhibitors
11/27/2003WO2003097598A1 Compound exhibiting pgd 2 receptor antagonism
11/27/2003WO2003097062A1 Phenyl substituted imidazopyridines and phenyl substituted benzimidazoles
11/27/2003WO2003097053A1 Compounds, compositions, and methods
11/27/2003WO2003097044A1 Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
11/27/2003WO2003059881A3 Dna minor groove binding compounds
11/27/2003WO2003047417A3 Ep4 receptor agonist, compositions and methods thereof
11/27/2003WO2003024899A3 CYCLIC HYDROXAMIC ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND/OR TNF-α CONVERTING ENZYME (TACE)
11/27/2003WO2003009850A1 Substituted piperazines as modulators of the melanocortin receptor
11/27/2003US20030220494 Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
11/27/2003US20030220493 Selectively inhibit binding to the alpha -1a adrenergic receptor; chemical intermediates
11/27/2003US20030220469 Novel compound used as an amino-protecting group, process for preparing the same, and synthetic method of a peptide using the same
11/27/2003US20030220388 Indoline derivatives
11/27/2003US20030220375 N-biphenyl(substituted methyl) aminocycloalkane-carboxamide derivatives
11/27/2003US20030220371 Administering to a mammal an aromatic or heteroaromatic ring substituted triazole derivative to treat the conditions mediated by angiogenesis, such as cancer, haemangioma, proliferative retinopathy, rheumatoid arthritis, and obesity
11/27/2003US20030220359 Substituted pyrimidine-sulfonamide derivatives are used as endothelin receptor antagonists
11/27/2003US20030220357 Reacting an aniline derivative with an acylchloride to form an intermeidate, cyclizing the intermediate, replacing hydroxy group with a leaving group (chloride), racting the product with an amino-heterocyclic compound
11/27/2003US20030220355 Useful as specific inhibitors of type-13 matrix mettaloprotease; for treating inflammatory conditions such as rheumatoid arthritis or osteoarthritis, and proliferative conditions such as cancers, particularly human breast cancer
11/27/2003US20030220348 Substituted imidazolylmethyl pyridine and pyrazine deriviatives GABAa receptor ligands
11/27/2003US20030220347 Compounds and methods for treatment of asthma, allergy and inflammatory disorders
11/27/2003US20030220341 Chemokine receptor binding heterocyclic compounds with enhanced efficacy
11/27/2003US20030220338 Fungal efflux pump inhibitors
11/27/2003US20030220332 Useful in the treatment of inter alia benign prostatic hyperplasia
11/27/2003US20030220331 6-Azauracil derivatives as IL-5 inhibitors
11/27/2003US20030220330 Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto
11/27/2003US20030220324 Substituted piperazines and methods of use
11/27/2003US20030220319 Such as 1-(4,5-dihydro-1H-imidazol-2-ylmethyl)-3-methanesulfonyl-2-methyl-1H-indole for preventing/treating disorders modulated by alpha-1A/L adrenoceptors such as urinary incontinence and sexual disorders
11/27/2003US20030220318 New phenylalanine derivatives
11/27/2003CA2486097A1 N-substituted tricyclic 3-aminopyrazoles as pdfg receptor inhibitors
11/27/2003CA2485214A1 1-oxa-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
11/27/2003CA2484631A1 Phenyl substituted imidazopyridines and phenyl substituted benzimidazoles
11/27/2003CA2484324A1 Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
11/26/2003EP1364949A1 Jnk inhibitor
11/26/2003EP1363906A2 Heterocyclic inhibitors of erk2 and uses thereof
11/26/2003EP1363905A1 Pyrazolyl pyrimidines
11/26/2003EP1363903A1 Indole derivatives and their use as gnrh antagonists
11/26/2003EP1363902A1 Chemical compounds
11/26/2003EP1363899A1 Quinazolone derivatives as alpha 1a/b adrenergic receptor antagonists
11/26/2003EP1363898A1 Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
11/26/2003EP1363889A1 Novel diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres
11/26/2003EP1363881A2 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
11/26/2003EP1363876A1 Glucocorticoid receptor modulators
11/26/2003EP1363705A1 Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
11/26/2003EP1363638A2 Use of gal3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
11/26/2003EP1363632A1 Receptor selective cannabimimetic aminoalkylindoles
11/26/2003EP1363631A2 Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
11/26/2003EP1363630A2 Kappa opioid receptor ligands
11/26/2003EP0760375B1 Antitumor indolopyprolocarbazole derivative
11/26/2003EP0689436B1 Taxanes not having an oxo group at c-9 and pharmaceutical compositions containing same
11/26/2003EP0673937B1 Bicyclic heterocyclic sulfonamide and sulfonic ester derivatives
11/26/2003CN1458922A Urea derivative and adhesive-molecule inhibitor containing same as ctive ingredient
11/26/2003CN1128807C Novel triazine-based detoxification agents and their use
11/26/2003CN1128788C Benzyl(idene)-lactam derivatives, their prepn. and their use as selective(ant) agonists of 5-HT 1A and/or 5-HT 1D receptors
11/26/2003CN1128617C Preparation method for medicinal composition containing triazolyl derivative
11/25/2003US6653475 Coupling a compound with pyrimidone intermediate
11/25/2003US6653471 Tricyclic heteroaromatic compounds containing pyrrole ring; central nervous system disorder treatment; side effect reduction
11/25/2003US6653308 Anticancer agents; antidiabetic agents; antiinflammatory agents
11/25/2003US6653306 Epoxy-steroidal aldosterone antagonist and angiotensin II antagonist combination therapy
11/25/2003US6653304 Antiarthritic agents; skin disorders; anticarcinogenic agents
11/25/2003US6653301 For therapy of cancer, diabetes and Alzheimer's disease
11/25/2003US6653300 Pyrazole compounds useful as protein kinase inhibitors
11/25/2003US6653086 Fusion protein; ligand has not been identified; screening for agonists/ antagonists
11/25/2003CA2106370C Antibiotic compounds
11/20/2003WO2003095433A1 Hexahydro-pyridazine-3-carboxylic acid derivatives, pharmaceutical compositions containing same and preparation methods thereof
11/20/2003WO2003095432A1 Benzimidazole derivatives
11/20/2003WO2003095430A1 Substituted pyrazolyl compounds for the treatment of inflammation
11/20/2003WO2003094918A1 Substituted piperazine as melanocortin receptors ligands
11/20/2003WO2003094839A2 Pyrimidinone compounds, compositions and methods
11/20/2003WO2003048130A3 Peroxisome proliferator activated receptor agonists
11/20/2003WO2003032984A8 2-phenyl benzimidazoles and imidazo-[4,5]-pyridines as cdsi/chk2-inhibitors and adjuvants to chemotherapy or radiation therapy in the treatment of cancer
11/20/2003WO2003029210A3 Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
11/20/2003WO2003027076A3 1h-imidazole derivatives having cb1 agonistic, cb1 partial agonistic or cb1- antagonistic activity
11/20/2003WO2003014105A9 Bicyclic compound, production and use as hiv inhibitors
11/20/2003WO2003006447A3 Interaction inhibitors of tcf-4 with beta-catenin
11/20/2003WO2002102315A3 QUINAZOLINE AND PYRIDO[2,3-d]PYRIMIDINE INHIBITORS OF PHOSPHODIESTERASE (PDE) 7
11/20/2003WO2002095022A3 Sequence-specific dna binding compounds and their use in targeting telomeres and other dna sequences
11/20/2003WO2002041910A3 Methods and compositions for the treatment of diseases of the eye
11/20/2003WO2002028861A8 Methods and compounds for treating proliferative diseases
11/20/2003US20030216569 Viricides; Aids therapy
11/20/2003US20030216462 Anticancer agents; psoriasis
11/20/2003US20030216460 N3 alkylated benzimidazole derivatives as MEK inhibitors
11/20/2003US20030216450 Inhibitors of dipeptidyl peptidase IV
11/20/2003US20030216410 Administering to a cancer patient an indole-2-one derivative containing pyrrole ring as protein kinase inhibitor together with a cyclooxygenase inhibitor to treat the cancer
11/20/2003US20030216406 Pyrimidine derivatives
11/20/2003US20030216402 Administering to the living body a oxo-azabicyclo derivative to treat disease selected from arthritis, osteoporosis, periodontal diseases, inflammatory bowel disease, psoriasis, multiple sclerosis, asthma, cancer and macular degeneration
11/20/2003US20030216390 Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues
11/20/2003US20030216385 Triazole derivatives
11/20/2003US20030216383 Compounds useful as reversible inhibitors of cysteine proteases
11/20/2003US20030216382 Useful for the treatment and/or prophylaxis of diseases associated with dipeptidyl peptidase, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance