Patents
Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587)
09/2008
09/12/2008WO2008070507A3 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
09/12/2008WO2008070016A3 Inhibitors of akt activity
09/12/2008WO2004078116A9 P38 inhibitors and methods of use thereof
09/12/2008CA2680177A1 Metalloprotease inhibitors containing a heterocyclic moiety
09/12/2008CA2680055A1 Novel 2-heteroaryl substituted indoles 695
09/12/2008CA2679670A1 Indole and benzothiophene compounds as modulators of the histamine h3 receptor
09/12/2008CA2679411A1 Ppar active compounds
09/12/2008CA2679380A1 Sulfonylated heterocycles useful for modulation of the progesterone receptor
09/12/2008CA2679101A1 Heterocyclic compounds, compositions comprising them and methods of their use
09/12/2008CA2678492A1 Bicyclic organic compounds suitable for the treatment of inflammatory or allergic conditions
09/12/2008CA2675312A1 1-biarylazetidinone derivative
09/11/2008US20080221322 Chemical process
09/11/2008US20080221187 N-substituted pyrazolyl-amidyl-benzimidazolyl c-Kit inhibitors
09/11/2008US20080221178 Benzimidazole Derivatives,Compositions Containing Them, Preparation Thereof and Uses Thereof
09/11/2008US20080221157 (2S)-2-{[(5-Methoxy-2-methyl-1H-indol-3-yl)acetyl]amino}-8-oxo-N-[2-(2-phenyl-1H-indol-3-yl)ethyl]nonanamide; treating neurodegenerative diseases, schizophrenia and stroke
09/11/2008US20080221152 4-(heteroaryl-methyl and substituted heteroaryl-methyl)-imidazole-2-thiones acting as alpha2 adrenergic agonists
09/11/2008US20080221151 In which the amino is substituted by arylmethyl- or heteroarylmethyl- group, e.g., 2-Methoxybenzyl)-(2-phenylpyrrolidin-3-yl)-amine and 5-{[2-(3-Chloro-phenyl)-pyrrolidin-3-ylamino]-methyl}-6-methoxy-3-methyl-1,1a,3,7b-tetrahydro-3-aza-cyclopropa[a]naphalen-2-one; neurokinin 1 (Substance P) inhititors
09/11/2008US20080221146 Inhibit the multimerization of nucleophosmin; cancer
09/11/2008US20080221139 Novel Compounds
09/11/2008US20080221137 Sodium channel moderators; antiarrhythmia agents; analgesics; antiarthritic agents; antiinflammatory agents; antieplipetic agents; psychological disorders; nervous system disorders
09/11/2008US20080221123 geranylgeranyltransferase I inhibitors; treatment of neoplasia, hyperproliferative cell growth, psoriasis, intimal hyperplasia (restinosis) and chronic inflammatory diseases including rheumatoid and osteoarthritis
09/11/2008US20080221122 cancer and non-cancer diseases associated with vascular proliferation; mitoxantrone resistant, taxol resistant cancers
09/11/2008US20080221112 New utilities of amide compounds
09/11/2008US20080221086 Novel Inhibitors of Glutaminyl Cyclase
09/11/2008US20080221082 of the alpha V beta 3 integrin receptor; , thromboembolic events, cardiovascular disorders, lung diseases, disorders of the CNS, the kidney, the gastrointestinal tract or inflammation
09/11/2008US20080221063 4-(3-Chloro-1H-indole-6-sulfonyl)-1-[1-(1-methyl-6-oxo-1,6-dihydro-pyridazin-3-yl)-piperidin-4-ylmethyl]-6-oxo-piperazine-2-carboxylic acid for example; antithrombotic and anticoagulant; synthesis; combination therapy
09/11/2008US20080220286 Electroluminescent compound; high color purity, high fluorescence yield, and high electric luminance yield; easy to synthesize and can easily form films
09/11/2008US20080217580 Organic Luminescent Element
09/11/2008US20080216606 Grinding to uniform particle size; heating; pressurization;; extraction from ores, concentrates
09/10/2008EP1966187A1 Piperazine compounds useful as antagonists of c-c chemokines (ccr2b and ccr5) for the treatment of inflammatory diseases
09/10/2008EP1966183A1 Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
09/10/2008EP1966165A1 Pyrazine derivatives as epithelial sodium channel blocker
09/10/2008EP1966164A1 Novel substituted pyrazinone derivatives for use in mch-1 mediated diseases
09/10/2008EP1966162A2 Pyrimidine derivatives
09/10/2008EP1966161A1 Carboxamides for controlling undesired micro-organisms in plant protection
09/10/2008EP1966159A2 Chemical compounds
09/10/2008EP1966151A1 Polycyclic indazole derivatives that are erk inhibitors
09/10/2008EP1966146A1 4,5-dihydro- (1h)-pyrazole derivatives as cannabinoid cb1 receptor modulators
09/10/2008EP1966144A1 Nicotinic acid derivatives as modulators of metabotropic glutamate receptors
09/10/2008EP1966134A1 Novel fused pyrrole derivatives
09/10/2008EP1646389B1 Pyrimidine-2,4-dione derivatives as gonadotropin-releasing hormone receptor antagonists
09/10/2008EP1438053B1 Pyrimidine derivatives, pharmaceutical agent containing said compounds, use and method for making same
09/10/2008EP1362856B1 Water-soluble triazole fungicide
09/10/2008EP1323710B1 Nitrogenous five-membered ring compounds
09/10/2008CN101263136A Benzimidazole derivatives as 5-HT6, 5-HT24
09/10/2008CN101263125A Quinazoline derivatives useful in cancer treatment
09/10/2008CN101263124A Quinazoline derivatives useful in cancer treatment
09/10/2008CN101263120A 4,5-dihydro-1h-pyrazole derivatives, their preparation and use as medicaments
09/10/2008CN101263116A Novel heterobicyclic derivatives useful as inhibitors of liver carnitine palmitoyl transferase
09/10/2008CN101263112A Histamine H3 receptor agents, preparation and therapeutic uses
09/10/2008CN101260104A Inhibition of phosphoinositide 3-kinase beta
09/10/2008CN101260103A Compound with portion PPARgamma excitant activity and application thereof
09/10/2008CN101260102A Antineoplastic activity marine indole alkaloids substances, and preparation method and application thereof
09/09/2008US7423159 Agent for preventing or treating neuropathy
09/09/2008US7423157 Substituted benzimidazoles and their use for inducing apoptosis
09/09/2008US7423155 (Meth)acrylates, e.g., 2-(p-(succinimidyl)sulfonyl)benzoyloxy)ethyl methacrylate; used for immobilization of amine-containing materials such as amino acidss, peptides, proteins, enzymes, immunoglobulins, DNA, RNA to substrate surfaces
09/09/2008US7423148 Small molecule PI 3-kinase inhibitors and methods of their use
09/09/2008US7423058 Inhibitors of hepatitis C virus NS3 protease
09/09/2008US7423049 e.g., 2-(5-fluoro-2-tolyl)-4-(4-aminocarbonylpiperazinylmethyl)-6-[a-aminocarbonyl-2,6-dichlorobenzyl]pyridine; mitogen-activated protein kinase inhibitor; antiinflammatory agent, autoimmune diseases
09/09/2008US7423048 eating disorders of disturbed fundus such as dyspepsia, early satiety, bloating, anorexia; fundic relaxation; 1-(1-((2,3-dihydro(1,4)dioxino(2,3-b)pyridin-3-yl)methyl) -4- piperidinyl)-2-imidazolidinone; improved pharmacokinetics, less vasoconstriction, side effect reduction, sustain release
09/09/2008US7423039 (4-phenylpiperazin-1-yl)acylpiperidine derivatives, preparation thereof and application of same in therapeutics
09/09/2008US7423036 Long-acting betamimetics for the treatment of respiratory complaints
09/09/2008US7423030 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof
09/09/2008CA2460865C Quinoline derivatives as neuropeptide y antagonists
09/09/2008CA2252163C D-proline derivatives
09/09/2008CA2225756C Substituted cyanophenyl uracils
09/04/2008WO2008106594A2 Inhibitors of nucleophosmin (npm) and methods for inducing apoptosis
09/04/2008WO2008105408A1 Novel pyrrole derivative having ureide group and aminocarbonyl group as substituents
09/04/2008WO2008105392A1 3-amino-2-indolylbutyrolactam derivative, process for production of the same, and pharmaceutical agent comprising the same as active ingredient
09/04/2008WO2008104754A1 Novel pyrimidine derivatives 698
09/04/2008WO2008104580A1 New use of glutaminyl cyclase inhibitors
09/04/2008WO2008104077A1 Small molecule inhibitors of protein arginine methyltransferases (prmts)
09/04/2008WO2008104055A1 Indole and indoline cyclopropyl amide derivatives as ep4 receptor antagonists
09/04/2008WO2008086462A3 AMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF β-CANTENIN/TCF-4 PATHWAY AND CANCER TREATMENT AGENTS
09/04/2008US20080214831 Copper-catalysed ligation of azides and acetylenes
09/04/2008US20080214813 ethyl 2-(2-chloropyrimidin-4-yl)-1H-indole-5-carboxylate; intermediates for preparing Ikb kinase inhibitors
09/04/2008US20080214810 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound
09/04/2008US20080214645 Administering 2-(1H-1-Indol-3-ylsulfanyl)benzyl]dimethyl amine; general anxiety disorder, social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, panic attacks, specific phobias, social phobia and agoraphobia
09/04/2008US20080214644 [2-(4-Fluoro-]. H-indol-3-ylsulfanyl)benzyl]dimethyl amine; depression, anxiety disorders including general anxiety disorder, social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, panic attacks
09/04/2008US20080214640 3'-{[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydropyrazol-4-ylidene]hydrazino}-2'-hydroxybiphenyl-3-carboxylic acid or a salt; treatment of thrombocytopenia; may be coadministered with a colony stimulating factor, cytokine, chemokine, or an interleukin or cytokine receptor agonist or antagonist
09/04/2008US20080214637 use of catalytic amounts of organic acids to prepare losartan, irbesartan and olmesartan medoxomil or their salts, and candesartan cilexetil
09/04/2008US20080214635 Modulation of pathogenicity
09/04/2008US20080214614 reduces intraocular pressure; primary open-angle glaucoma; effective to influence the actomyosin interactions by leading to cellular relaxation and alterations in cell-substratum adhesions
09/04/2008US20080214613 Substituted benzimidazole compounds with dual NOS inhibitory activity and mu opioid agonist activity
09/04/2008US20080214559 Compounds with a combination of cannabinoid cb1 antagonism and serotonin reuptake inhibition
09/04/2008US20080214558 2-[(2-(4-methylpyrazin-1-yl)-3-fluoro-5-pyridinyl)amino]-4-[(3-chloro-4-fluoro) or (3-cyanomethyl)phenylamino]pyrimidine; 2-[(4-(4-methylpyrazin-1-yl)-phenyl)amino]-4-[(3-chloro-4-fluoro) or (3-cyanomethyl)phenylamino]pyrimidine; colon, breast, stomach, urogenital, pancreatic cancers, leukemia lymphoma
09/04/2008US20080214553 2-(4-Oxo-4H-Quinazolin-3-Yl) Acetamides and Their Use as Vasopressin V3 Antagonists
09/04/2008US20080214552 Substituted Pyridazinecarboxamides and Derivatives Thereof
09/04/2008US20080214544 N-(4-(6-(1-methyl-6-oxo-2-(phenylamino)-1,6-dihydropyrimidin-5-yl)pyridin-3-yloxy)pyridin-2-yl)pyrrolidine-1-carboxamide; anticarcinogenics, antiproliferatives, angiogenesis inhibitors; hepatocyte growth factor mediated diseases
09/04/2008US20080214542 1-(5-methoxyisoindolin-2-yl)-6-[4-(3-trifluoromethylphenyl)piperazin-1-yl]hexan-1-one; amidation of an isoindole with a 4-phenylpyrimidinylalkanoic acid or amination of a N-haloalkylcarbonyl isoindole with a 4-phenylpyrimidine; antidepressant, neuroleptic agent; drug abuse, impotency, Parkinson's Disease
09/04/2008US20080210858 High Stability Polyionic Liquid Salts
09/04/2008CA2679446A1 New use of glutaminyl cyclase inhibitors
09/04/2008CA2679312A1 Co-crystals and pharmaceutical compositions comprising the same
09/04/2008CA2679175A1 Indole and indoline cyclopropyl amide derivatives as ep4 receptor antagonists
09/04/2008CA2678735A1 Novel pyrrole derivative having ureido group and aminocarbonyl group as substituents
09/03/2008EP1964839A2 Quinazoline derivatives as kinase inhibitors
09/03/2008EP1963309A1 Method for producing metal salts of losartan
09/03/2008EP1963308A2 Method for making nicotine hapten
09/03/2008EP1963286A1 Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same
09/03/2008EP1963285A1 Bradykinin 1 receptor antagonists