Patents
Patents for C07D 403 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group (62,587)
11/2008
11/06/2008CA2685106A1 6-phenylpyrimidinones as pim modulators
11/06/2008CA2683159A1 Isoquinolinone derivatives as nk3 antagonists
11/05/2008EP1988091A1 Tricyclic compounds
11/05/2008EP1988090A1 Imidazol-5-carboxylic acid derivatives, preparation methods and use therrof
11/05/2008EP1988076A1 Amide derivative or salt thereof
11/05/2008EP1988075A1 Pyrrole derivative or salt thereof
11/05/2008EP1987831A1 Compounds effecting glucokinase
11/05/2008EP1987028A2 Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors
11/05/2008EP1987022A1 Pyridinone pyrazole urea and pyrimidinone pyrazole urea derivatives
11/05/2008EP1987021A1 Substituted prolinamides, their preparation and their use as pharmaceuticals
11/05/2008EP1987003A1 Pyridine-2-carboxamide derivatives
11/05/2008EP1986646A1 Novel azacycly-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
11/05/2008EP1824844B1 Pyrazine dicarboxamides and the use thereof
11/05/2008EP1732921B1 Thioamide derivatives as progesterone receptor modulators
11/05/2008EP1713781B1 Quinazoline derivatives
11/05/2008EP1664032B1 N-substituted pyrazolyl-amidyl-benzimidazolyl c-kit inhibitors
11/05/2008EP1663970B1 Matrix metalloproteinase inhibitors
11/05/2008EP1608374B1 2-phenoxy- and 2-phenylsulfomamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders
11/05/2008EP1296973B1 Guanidine derivatives of quinazoline for use in the treatment of autoimmune diseases
11/05/2008EP1200424B1 C7 heterosubstituted acetate taxanes as antitumor agents
11/05/2008CN101300249A Aminoquinoline and aminoquinazoline kinase modulators
11/05/2008CN101300236A Triazole compounds as lipoxygenase inhibitors
11/05/2008CN101300235A Diaminopyrimidines as P2X3 and P2X2/3 modulators
11/05/2008CN101298433A 2-, 3-, 4-, or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
11/05/2008CN100430390C Water-soluble triazole fungicide
11/05/2008CN100430389C Inhibition of phsphoinostide 3-dinase beta
11/05/2008CN100430388C Improved process for preparing alpha-polymorphic eletriptan hydrobromide
11/05/2008CN100430386C Phenylalanine derivatives as depeptidyl peptidase inhibitors for the treatment or prevention of diabetes
11/05/2008CN100430060C Combination administration of an indolinone with a chemotherapeutic agent for cell proliferation disorders
11/04/2008US7446212 Polymethine ethers
11/04/2008US7446195 High affinity thiophene-based and furan-based kinase ligands
11/04/2008US7446123 Azabicyclo derivatives as muscarinic receptor antagonists
11/04/2008US7446109 Carbonylamino-derivatives as novel inhibitors of histone deacetylase
11/04/2008US7446106 Pyridylfurans and pyrroles as Raf kinase inhibitors
11/04/2008US7446105 4-(1,2-diethyl-4-methylimidazol-5-yl)-2-{4-[N-(2-methoxyethyl)sulphamoyl]anilino}pyrimidine; selectivity for cyclin-dependent serine/threonine kinases (CDK2, CDK4 and CDK6); antiproliferative agent; minimize pharma toxicity on S-phase cell cycle, G2 or mitosis; oncogene signalling pathways
11/04/2008US7446103 N-[4-(3-Piperidin-1-ylpropoxy)-benzoyl]-5-fluoroisoindoline; Alzheimer's disease; cognition enhancers; amidation
11/04/2008US7445767 Using water soluble dyes; contrast media for fluorescence
11/04/2008CA2443449C Pyrazole derivatives for treating hiv
10/2008
10/30/2008WO2008131253A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
10/30/2008WO2008131227A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
10/30/2008WO2008131103A2 Drug discovery methods for aurora kinase inhibitors
10/30/2008WO2008130970A1 7-nonsubstituted indole mcl-1 inhibitors
10/30/2008WO2008130879A2 Tetrahydroindole and tetrahydroindazole derivatives
10/30/2008WO2008130368A2 Transcription factor modulating compounds and methods of use thereof
10/30/2008WO2008130313A1 Imidazole derivatives as modulators of the gaba receptor for the treatment of gastrointestinal disorders
10/30/2008WO2008130021A2 Heterocyclic hydrazide compound and pesticidal use of the same
10/30/2008WO2008129951A1 Novel pyrimidine compound having dibenzylamine structure, and medicine comprising the compound
10/30/2008WO2008129380A1 Sulfonyl amide derivatives for the treatment of abnormal cell growth
10/30/2008WO2008129080A1 4, 6-disubstituted aminopyrimidine derivatives as inhibitors of protein kinases
10/30/2008WO2008129075A1 Substituted 3-(4-hydroxyphenyl)-indolin-2-one-compounds
10/30/2008WO2008129069A1 Inhibitors of protein kinases
10/30/2008WO2008128984A1 Aminopyrimidine derivatives as glutaminyl cyclase inhibitors
10/30/2008WO2008128982A1 Thioxoquinazolinone derivatives as glutaminyl cyclase inhibitors
10/30/2008WO2008128968A1 Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5
10/30/2008WO2008128921A1 Process for hcv protease inhibitor intermediate
10/30/2008WO2008128891A1 Pyrrolidine derivatives as dual nk1/nk3 receptor antagonists
10/30/2008WO2008128711A1 Insecticidal aryl pyrrolidines
10/30/2008WO2008074752A3 Indolylmaleimide derivatives as kinase inhibitors
10/30/2008WO2007109211A8 1-oxo-isoindoline compounds for the treatment of spinal muscular atrophy and other uses
10/30/2008WO2007100610A3 Pyridine, pyrimidine and pyrazine derivatives as cxcr3 receptor modulators
10/30/2008US20080269502 Process for the preparation of macrocyclic compounds
10/30/2008US20080269489 Resolution by diastereomeric salt formation and crystallisation is easier to apply industrially; obtain partially enriched mixture of substantially enantiomerically pure (S)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
10/30/2008US20080269487 6-{[1-(carbamoylmethyl)piperidin-4-yl]oxy}-4-(3-chloro-2-fluoroanilino)-7-methoxyquinazoline; prevent, treat tumours which are sensitive to inhibition of erbB receptor tyrosine kinases
10/30/2008US20080269305 R)-N-{2-Butyl-3-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazol-4-ylmethyl}-2-(2-hydroxycarbamoyl-3-phenyl-propionylamino)succinamic Acid; AT1 receptor antagonist and neprilysin (NEP) enzyme inhibition activity; hypertension, heart failure
10/30/2008US20080269267 Anticancer agents; rheumatic diseases; asthma; chronic obstructive pulmonary disease; neurodegenerative diseases; metabolic disorders
10/30/2008US20080269254 Antiproliferative agents; anticancer agents; graft versus host disease; rheumatic diseases; vision defects; cardiovascular disorders
10/30/2008US20080269251 Central nervous system disorders; psychological disorders; anxiolytic agents; antidepressants; Parkinson's disease; Alzheimer's disease; analgesics; neurodegenerative diseases; sexual disorders
10/30/2008US20080269250 Pyrrolidine and Piperidine Acetylene Derivatives for Use as Mglur5 Antagonists
10/30/2008US20080269249 Controlling intraocular pressure
10/30/2008US20080269235 e.g. 5-Acetyl-4-[(3,5-difluorophenyl)amino]-2-ethyl-6-phenylpyridazin-3(2H)-one; Tumor Necrosis Factor alpha antagonist; antiinflammatory agent, autoimmune diseases; chronic obstructive pulmonary disease, rheumatoid arthritis, psoriasis, ulcerative colitis, and Crohn's disease
10/30/2008US20080269233 Piperidinoyl-Pyrrolidine and Piperidinoyl-Piperidine Compounds
10/30/2008US20080269232 Pyridazine compound; also useful against rhinovirus
10/30/2008US20080269228 Hydrazide-containing hepatitis c serine protease inhibitors
10/30/2008US20080269224 Substituted Triazines as Prion Protein Ligands and Their Use to Detect or Remove Prions
10/30/2008US20080269217 Melanocortin-4 receptor binding compounds and methods of use thereof
10/30/2008US20080269214 Therapy for bacteria infections
10/30/2008US20080269212 Anticancer agents
10/30/2008US20080269211 Antiserotonine agents; gastrointestinal disorders; irritable bowel syndrome; central nervous system disorders; Alzheimer's disease; cognition activators; analgesics; cardiovascular disorders; antidiabetic agents; sleep disorders
10/30/2008US20080269207 Anticancer agents; such as 4-acetylamino-1H-pyrazole-3-carboxylic acid (4-fluoro-phenyl)-amide
10/30/2008US20080269201 Central nervous system disorders; respiratory system disorders; sexual or reproductive disorders; gastrointestinal disorders; eating disorders; antidiabetic agents; anticancer agents
10/30/2008US20080269200 Antiinflammatory agents; tissue repair; rheumatic disorders; asthma; chronic onstructive pulmonary disease; osteoporosis; psoriasis; Alzheimer's disease; transplant rejection; stroke; antidiabetic agents; glomerulonephritis; anticancer agents
10/30/2008US20080269193 Inhibition of heat shock protein diseases; antiproliferative agents; antiarthritic agents; antiinflammatory agents; autoimmune diseases; stroke; antiischemic agents; cardiovascular disorders; antitumor agents; anticancer agenst
10/30/2008US20080269170 Novel 2,4-Dianilinopyrimidine Derivatives, the Preparation Thereof, Their Use as Medicaments, Pharmaceutical Compositions and, in Particular, as IKK Inhibitors
10/30/2008US20080267911 Imidazole derivatives; Alzheimer's Disease, Down syndrome and Huntington's Disease; hypotensive agents; sleeping and eating disorders, anxiolytic agents, antidepressants, antiepileptic agents; drug abuse/withdrawl; 1-(3,4-dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)thiourea
10/30/2008US20080267892 Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair
10/30/2008US20080267867 Imidazole, pyridine derivative silver complexes; nanofiber with radioactive transition metal, lanthanide, actinide; radiopharmaceutical peptide, polyamine, imaging and tumor treatment
10/30/2008US20080265758 Organometallic complexes and organic electroluminescence device using the same
10/30/2008CA2685141A1 New compounds 806
10/30/2008CA2684950A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
10/30/2008CA2684949A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
10/30/2008CA2684651A1 Insecticidal aryl pyrrolidines
10/30/2008CA2684552A1 Substituted 3-(4-hydroxyphenyl)-indolin-2-one compounds
10/30/2008CA2684240A1 Tetrahydroindole and tetrahydroindazole derivatives
10/30/2008CA2684086A1 Process for hcv protease inhibitor intermediate
10/30/2008CA2683534A1 Novel pyrimidine compound having dibenzylamine structure and medicament comprising the same
10/30/2008CA2682676A1 Nicotinic acid derivatives as modulators of metabotropic glutamate receptor-5
10/30/2008CA2682506A1 Pyrrolidine derivatives as dual nk1/nk3 receptor antagonists
10/30/2008CA2682354A1 7-nonsubstituted indole mcl-1 inhibitors
10/30/2008CA2681779A1 Heterocyclic hydrazide compound and pesticidal use of the same
10/30/2008CA2656157A1 Transcription factor modulating compounds and methods of use thereof