Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
03/2008
03/06/2008WO2008027466A1 Hydantoin derivatives useful as antibacterial agents
03/06/2008WO2008026769A1 Novel aminopyridine derivative having aurora a-selective inhibitory activity
03/06/2008WO2008026768A1 Novel aminopyridine derivatives having aurora a selective inhibitory action
03/06/2008WO2008026704A1 Isoquinoline derivative
03/06/2008WO2008026658A1 N-pyridylpiperidine compound, method for producing the same, and pest control agent
03/06/2008WO2008026577A1 Method for producing phenoxypyridine derivative
03/06/2008WO2008026220A1 A process for purification of 7-(4-bromobutoxy)-3,4 dihydrocarbostyril, an intermediate for manufacture of aripirazole
03/06/2008WO2008026219A2 Novel polymorphs of rimonabant
03/06/2008WO2008025886A1 Metal chelates and chelating agents containing triazolyl subunits
03/06/2008WO2008025820A1 Aminopyridine derivates as kinase inhibitors
03/06/2008WO2008025800A1 Pyrimidine compounds for treating gpr119 related disorders
03/06/2008WO2008025799A1 Pyridazine compounds for treating gpr119 related disorders
03/06/2008WO2008025798A1 Pyridine compounds for treating gpr119 related disorders
03/06/2008WO2008025735A1 Substituted oxindole derivatives and their use as vasopressin and/or oxytocin receptor ligands
03/06/2008WO2008025540A1 Heterocyclic fxr binding compounds
03/06/2008WO2008025526A1 Indole derivatives, their manufacture and use as pharmaceutical agents
03/06/2008WO2008025152A1 Antibacterial agents
03/06/2008WO2008014361A3 Cyclic derivatives as modulators of chemokine receptor activity
03/06/2008WO2008011176A9 Myosin light chain kinase inhibitor compounds, compositions and related methods of use
03/06/2008WO2008011131A3 Amide compounds
03/06/2008WO2008008375A3 Triazolyl pyridyl benzenesulfonamides as ccr2 or ccr9 modulators for the treatment of inflammation
03/06/2008WO2007146225A3 Heterocyclic aspartyl protease inhibitors
03/06/2008WO2007131201A3 Compounds and compositions as hedgehog pathway modulators
03/06/2008WO2007117607A9 Quinazolines for pdk1 inhibition
03/06/2008US20080058543 Process for making chiral 1,4-disubstituted piperazines
03/06/2008US20080058523 Processes for synthesizing piperazine-piperidine compounds
03/06/2008US20080058515 indazolylacrylamide derivatives are useful in the treatment of diseases associated with inappropriate SGK-1 activity
03/06/2008US20080058386 1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-ylamine; inhibiting tubulin polymerization; anticarcinogenic; mitotic arrest of microtubule structure, neovascularization; angiogenesis inhibitor: atherosclerosis, rheumatoid arthritis or Crohn's disease, diabetic retinopathy, psoriasis
03/06/2008US20080058385 For treatment of Type II diabetes, obesity
03/06/2008US20080058384 Novel Compounds
03/06/2008US20080058383 Such as 2-methyl-2-(4-nitro-3-trifluoromethyl-phenylamino)-propan-1-ol; prostate cancer; cardiovascular disorders; psychological disorders
03/06/2008US20080058382 Polyamine compounds
03/06/2008US20080058380 2-{[2-(3,5-difluorophenyl)acetyl]amino}-N-{5-[2-(isopropoxymethyl)phenyl]-1,3-thiazol-2-yl}propanamide; neuroprotectant; neurodegenerative diseases: Alzheimer's and Parkinson's disease, Down syndrome, amyloid angiopathy and cerebrovascular disorders
03/06/2008US20080058379 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
03/06/2008US20080058376 Useful in treatment of diseases through the inhibition of sodium ion flux through voltage-dependent sodium channels; treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels; neuropathic pain
03/06/2008US20080058359 1-[[3-[(1,4,5,6-Tetrahydro-2-pyrimidinyl)amino]phenyl]acetyl]-4-piperidinepropanoic acid; new class of selective modulator of beta 3, beta 5 or dual integrin receptors; anticarcinogenic, antiinflammatory, antidiabetic agent
03/06/2008US20080058358 Anticancer/antitumor agents; S-(4-([4-([(1R,2R)-2-Hydroxy-1-methylpropyl]amino)-5-(trifluoromethyl)-pyrimidin-2-yl]amino)phenyl)-S-methyl-N-[(trifluoromethyl)sulphonyl]-sulphimide for example
03/06/2008US20080058357 Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4
03/06/2008US20080058356 2,6 Bisheteroaryl-4-Aminopyrimidines as Adenosine Receptor Antagonists
03/06/2008US20080058347 Novel aminopyridine derivatives having aurora a selective inhibitory action
03/06/2008US20080058344 Enantiomers of 2'-fluoralkyl-6-nitroquipazine as serotonin transporter positron emission tomography imaging agents and antidepressant therapeutics
03/06/2008US20080058343 Heterocyclic substituted piperazine compounds with cxcr3 antagonist activity
03/06/2008US20080058342 potent kinase insert domain-containing receptor (KDR) inhibitors with improved selectivity and pharmacokinetics; VEGF (vascular endothelial growth factor) inhibitors; cancer and rheumatoid arthritis; e.g. 7-(2-[4-(acetylmethyl)piperazin-1-yl]ethoxy)-6-methoxy-4-[(2-methyl-1H-indol-5-yl)oxy]quinazoline
03/06/2008US20080058341 Azaindazole compounds and methods of use
03/06/2008US20080058339 4-phenyl-3-substituted pyridazine compounds such as tert-Butyl 4-[((6-[4-(methylsulfonyl)phenyl]pyridazin-3-yl)oxy)methyl]-piperidine-1-carboxylate; agonists of the G-protein-coupled receptor GPR119; diabetes and obesity; use with a dipeptidyl peptidase IV (DPP IV) inhibitor
03/06/2008US20080058334 Dermatological or oncological disorders; N-(4-fluorophenyl)-N'-[4-[1-(1H-imidazol-1-yl)-2-methylpropyl]phenyl]urea for example
03/06/2008US20080058332 Antiproliferative, antitumor agents; 4-(3-hydroxyphenyl)-6-morpholino-2-(3-piperidin-4-ylcarbonylaminophenyl)pyrimidine for example
03/06/2008US20080058326 Interfere with Tie2 signalling; Tie (tyrosine kinase with immunoglobulin and epidermal growth factor homology domain) receptor tyrosine kinase; antitumor, antimetastasis agents; for example, 1-[4-(6-tert-Butyl-1H-pyrazolo[3,4-b]pyridin-4-yl)-phenyl]-3-(3-ethyl-phenyl)-urea
03/06/2008US20080058320 Organic Compounds
03/06/2008US20080058319 Fused ring heterocycles as potassium channel modulators
03/06/2008US20080058315 Integrase inhibitors
03/06/2008US20080058313 Tetrahydro-2h-indazole pyrazole cannabinoid modulators
03/06/2008US20080058311 Antagonizing N-type calcium channels; use as analgesic, neurodegenerative diseases, brain injury, bronchial asthma, unstable angina and irritable colitis, drug withdrawal symptoms; t-butyl 2-[4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-piperidinyl]-2-oxoethylcarbamate for example
03/06/2008US20080058297 Heterocyclic Compounds For Preventing And Treating Disorders Associated With Excessive Bone Loss
03/06/2008US20080057074 Nitrogenous Heterocylic Derivative and Medicine Containing the Same as an Active Ingredient
03/06/2008US20080056991 Histamine H3 receptor inhibitors; (4-Azepan-1-ylmethyl-phenyl)-(4-isopropyl-piperazin-1-yl)-methanone dihydrochloride for example; allergies, nasal congestion, eating disorders, sleep disorders, neurodegenerative disorders
03/06/2008CA2670271A1 Substituted oxindole derivatives, medicinal products containing them, and use thereof
03/06/2008CA2662274A1 Chemical compounds
03/06/2008CA2661741A1 N-pyridylpiperidine compound, method for producing the same, and pest control agent
03/06/2008CA2661702A1 Method for producing phenoxypyridine derivative
03/06/2008CA2661605A1 Hydantoin derivatives useful as antibacterial agents
03/06/2008CA2661371A1 Pyrimidine compounds for treating gpr119 related disorders
03/06/2008CA2660806A1 5-substituted isoindoline compounds
03/06/2008CA2660699A1 Pyridine compounds for treating gpr119 related disorders
03/06/2008CA2660376A1 Salts of benzimidazolyl pyridyl ethers and formulations thereof
03/06/2008CA2657469A1 Novel aminopyridine derivatives having aurora a selective inhibitory action
03/05/2008EP1894925A1 Imidazole compounds having an antiinflammatory effect
03/05/2008EP1894924A1 Heterocyclic FXR binding compounds
03/05/2008EP1893604A2 Method for producing n,n-bis(pyridin-2-yl-methyl)-1,1-bis(pyridin-2-yl)-1-aminoalkane compounds and metal complex salts containing these compounds
03/05/2008EP1893603A1 Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists
03/05/2008EP1893602A2 Pantoprazole free acid form iii
03/05/2008EP1893601A1 Thrombin inhibiting 2-oxo-1, 2, 5, 6-tetrahydropyridine derivatives
03/05/2008EP1893600A1 Trombin inhibiting 2,4-dioxo-3,4-dihydropyrimidine derivatives
03/05/2008EP1893599A1 Compounds for the treatment of multi-drug resistant bacterial infections
03/05/2008EP1893598A1 Alkylquinoline and alkylquinazoline kinase modulators
03/05/2008EP1893588A1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
03/05/2008EP1893584A1 Dihydropyrimidone multimers and their use as human neutrophil elastase inhibitors
03/05/2008EP1893581A1 Substituted arylpyrazoles for use against parasitites
03/05/2008EP1893578A2 Novel piperidine carboxylic acid amide derivatives
03/05/2008EP1893577A1 Biphenyl compounds useful as muscarinic receptor antagonists
03/05/2008EP1893574A2 Peptide deformylase (pdf) inhibitors 4
03/05/2008EP1893212A2 Multicyclic compounds and methods of their use
03/05/2008EP1893202A2 Multimediator dopamine transport inhibitors, and uses related thereto
03/05/2008EP1893200A2 Carbamate derivatives as positive allosteric modulators of metabotropic glutamate receptors
03/05/2008EP1893196A1 Diarylhydantoin compounds
03/05/2008EP1713797B1 1-isopropyl-2-oxo-1,2-dihydropyridine-3-carboxamide derivatives having 5-ht4 receptor agonistic activity
03/05/2008EP1644351B1 Imidazole derivatives and their use in the treatment of mGluR5 receptor mediated disorders
03/05/2008EP1633748B1 Quinoline derivatives as phosphodiesterase inhibitors
03/05/2008EP1575926B1 New pyridazin-3(2h)-one derivatives
03/05/2008EP1560811B9 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
03/05/2008EP1383733B1 Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds
03/05/2008EP1045836B1 Pyridones as src family sh2 domain inhibitors
03/05/2008EP0989993B1 Tartrate salt of a substituted dipeptide as growth hormone secretagogue
03/05/2008CN101137652A Pyrimidine compounds having tie2 (tek) inhibitory activity
03/05/2008CN101137649A Alkinyl-oxypyrimidine used in the form of pesticides
03/05/2008CN101137646A Synthesis of ccr5 antagonists
03/05/2008CN101137645A Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
03/05/2008CN101137644A 7-(2-(4-(3-trifluoromethyl-phenyl)-1,2,3,6-tetrahydropyrid-1-yl)ethyl)isoquinoline besylate salt, preparation and therapeutic use thereof
03/05/2008CN101137643A Novel pyridine compounds
03/05/2008CN101137623A N-sulphonylpyrroles and their use as histone deacetylase inhibitors