Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
03/2008
03/25/2008US7348346 Use as antidiabetic agents, treating hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis; (3S, 5S)-4-([5-(Thiazolidine-3-carbonyl)-pyrrolidin-3-ylmethyl]-sulfamoyl)-benzoic acid for example
03/25/2008US7348343 N-(N-heteroaryl)1-pyridyl- or -pyrimidyl-hydropyridine-4-carboxamides; e.g., 3'-Chloro-3,6-dihydro-2H-[1,2']bipyridinyl-4-carboxylic acid (6-trifluoromethyl-pyridin-3-yl)-amide and 1-pyrimidin-2-yl-1,2,3,6-tetrahydro-pyridine-4-carboxylic acid (6-trifluoromethyl-pyridin-3-yl)-amide
03/25/2008US7348342 5-(4-Fluorophenyl)-1-(4-methylsulfoximinylphenyl)-3-trifluoromethyl-1H-pyrazole; prostaglandin and cyclooxygenase inhibitor; antiinflammatory, analgesic, and antipyretic agent
03/25/2008US7348341 Chemical compounds
03/25/2008US7348340 "caused" by the stimulation of nociceptive receptors and transmitted over intact neural pathways; 2-(4-Chlorophenyl)-quinoline-4,6-diamine; acute, persistent and neuropathic pain
03/25/2008US7348338 PPAR active compounds
03/25/2008US7348337 heterocyclic oxo amides such as 1-[4-(1-Phenyl-1-(pyrazinyl)-methylene)-piperidin-1-yl]-2-(4-methoxy-7-pyrazinyl-6-azaindol-3-yl)-ethane-1,2-dione, used as viricides for prophylaxis of lympadenopathy associated virus; synergystic mixtures with immunomodulators
03/25/2008US7348335 Compositions useful as inhibitors of JAK and other protein kinases
03/25/2008US7348328 MCH antagonists for the treatment of obesity
03/25/2008US7348327 (2S)-4,4-difluoro-1-(2-{[1-(2-pyrazinyl)piperidin-4-yl]amino}acetyl)-2-pyrrolidine carbonitrile; enzyme inhibitors; diabetes
03/25/2008US7348326 in brain; (2,5-difluorodifluorophenyl)-N-methyl-N-((1-propylbenzimidazol-2-yl)methyl)carboxamide; anxiolitic and antidepressant; finding and altering the signal-transducing activity of gamma aminobutyric acid (GABA) receptors; detectably-labeled antagonist/agonist of GABAR
03/25/2008US7348325 Pyrrolotriazine kinase inhibitors
03/25/2008US7348324 Cyclic amine compounds as CCR5 antagonists
03/25/2008CA2288322C Block oligomers containing 1-hydrocarbyloxy-2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials
03/25/2008CA2268709C Hiv protease inhibitors
03/25/2008CA2268394C New heterocyclylmethyl-substituted pyrazol derivates
03/25/2008CA2250002C Cephem compounds and drugs containing the compounds
03/25/2008CA2173493C Fused pyridazine compounds
03/20/2008WO2008033931A1 Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib
03/20/2008WO2008033854A1 Certain substituted amides, method of making, and method of use thereof
03/20/2008WO2008033834A1 Pyrimidines derivatives and their use as kinase inhibitors
03/20/2008WO2008033764A2 Quinazolinone and isoquinolinone acetamide derivatives
03/20/2008WO2008033567A1 N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same
03/20/2008WO2008033465A1 Azetidinone derivatives and methods of use thereof
03/20/2008WO2008033455A2 Biphenyl and heteroaryl phenyl derivatives as protein tyrosine phosphatases inhibitors
03/20/2008WO2008032330A2 Improved process for rimonabant
03/20/2008WO2008032204A1 Substituted pyridylmethyl bicyclocarboxyamide compounds
03/20/2008WO2008032136A1 An improved process for the preparation of desloratadine
03/20/2008WO2008032091A1 4-benzimidaz0lyl-6-m0rph0lin0-2-piperidin-4-ylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032089A1 4-benzimidaz0lyl-2-m0rph0lin0-6-piperidin-4-ylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032086A1 2-benzimidazolyl-6-morpholino-4-phenylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032072A1 2-benzimidaz0lyl-6-m0rph0lin0-4-piperidin-4-ylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032060A1 4-benzimidaz0lyl-6-m0rph0lin0-2-piperazinylpyrimidine derivatives as p13k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032041A1 Pyrimidine derivatives having inhibitory activity against pi3k enzymes
03/20/2008WO2008032036A1 6-benzimidaz0lyl-2-m0rph0lin0-4- (azetidine, pyrrolidine, piperidine or azepine) pyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032033A1 4-benzimidazolyl-2-morpholino-6-piperazinylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008032028A1 2 -benzimidazolyl- 6 -morpholino-4- (azetidine, pyrrolidine, piperidine or azepine) pyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
03/20/2008WO2008031735A1 Pyridine- and quinoline-pyrimidine-derivatives
03/20/2008WO2008031734A1 5-phenyl-nicotinamide derivatives
03/20/2008WO2008031556A2 2 amino-pyrimidine derivatives as h4 receptor antagonists, processes for preparing them and their use in pharmaceutical compositions
03/20/2008WO2008031549A1 Process for the preparation of anthranilamide derivatives
03/20/2008WO2008031548A1 Process for the preparation of anthranilamide derivatives
03/20/2008WO2008031227A1 Diaryl piperidine compounds as calcium channel blockers
03/20/2008WO2008017466A8 Pharmaceutically active tetrahydroisoquinoline-substituted benzimidazole derivatives
03/20/2008WO2008014247A3 4 -arylalkoxymethyl-4- phenyl piperidines and their use as neurokinin receptor antagonists for the treatment of cns disorders
03/20/2008WO2008009750A3 Macrocyclic compounds useful as bace inhibitors
03/20/2008WO2008005910A3 Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
03/20/2008WO2007146341A9 Amorphous and crystalline forms of pantoprazole magnesium salt
03/20/2008WO2007144769A3 Aryl- and heteroaryl-ethyl-acylguanidine derivatives, their preparation and their application in therapeutics
03/20/2008WO2007144512A3 Diazeniumdiolate derivatives, method for the preparation thereof, pharmaceutical compositions thereof, and use of same in the fields of hypertension and cardiovascular pathologies
03/20/2008WO2007140174A3 Compounds and methods for modulating fxr
03/20/2008WO2007136510A3 Polymorphic forms of imatinib mesylate and processes for their preparation as well as of amorphous imatinib mesylate and form alpha
03/20/2008WO2007133983A3 2-aminobenzimidazoles for treating neurodegenerative diseases
03/20/2008WO2007113327A3 Fungicide n-cyclopropyl-sulfonylamide derivatives
03/20/2008WO2007080131A3 Anthranilamide derivatives and their use for the control of insects and acari
03/20/2008WO2007072092A8 New phenanthridine derivatives as bradykinin antagonists
03/20/2008WO2006094187A3 Phthalazine, aza- and diaza-phthalazine compounds and methods of use
03/20/2008US20080071089 Reacting rabeprazole with aqueous sodium hydroxide; salt formation; adding ethanol; agitation in nonsolvent; isolation
03/20/2008US20080071088 Drugs for respiratory system disorders; also chemical intermediate for such drugs
03/20/2008US20080070949 Polymorphs of rimonabant
03/20/2008US20080070948 Including indanones, indolinones and benzoxazolinones containing a piperidine ring, e.g., 1-[3-(4-(Hydroxymethyl)piperidin-1-yl)propyl]-1,3-dihydrobenzoimidazol-2-one; particularly for the M1 and/or M4 receptor subtypes; increase acetylcholine signaling or effect in the brain
03/20/2008US20080070945 4-(2-methyl-5,6,7,8-tetrahydro-quinolin-7-ylmethyl)-1,3-dihydro-imidazole-2-thione as specific alpha2b agonist and methods of using the same
03/20/2008US20080070935 Isoquinoline, Quinazoline and Phthalazine Derivatives
03/20/2008US20080070931 5-phenyl-nicotinamide derivatives
03/20/2008US20080070928 Novel 2-Heteroaryl-Substituted Benzimidazole Derivative
03/20/2008US20080070915 Poly(ADP-ribose)polymerase (PARP); ischemia, reperfusion injuries, neurological disorders, neuroprotectants, sensitizer for chemotherapy or radiotherapy, anticancer
03/20/2008US20080070913 Thieno [ 3,2-b] pyridine-6-carbonitriles and thieno [2,3-b] pyridine-5-carbonitriles as protein kinase inhibitors
03/20/2008US20080070912 Phosphodiesterase inhibitors; neuropathic pain, inflammation, opioid dependence or withdrawal; 2-amino-1-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one for example
03/20/2008US20080070906 Quinolinone derivatives
03/20/2008US20080070903 New pyrimidine derivatives and new pyridine derivatives
03/20/2008US20080070902 Cinnamide Compound
03/20/2008US20080070899 (Calcitonin gene related peptide); headache, migraine and cluster headache; spiropiperidine-substituted azepan-2-ones such as 1-(2,2,2-trifluoroethyl)-3-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl-aminocarbonylamino)6-(2,3-difluorophenyl)azepan-2-one
03/20/2008US20080070898 Sodium channel inhibitor of low side effect; analgesics; neuropathic pain; 4-(2-{4-[(E)-2-(2-methylphenyl)vinyl]piperidin-1-yl}-2-oxoethyl)morpholine for example
03/20/2008US20080070895 Heteroaryl substituted spirocyclic sulfamides for inhibition of gamma secretase
03/20/2008US20080070869 Malonyl-CoA Decarboxylase Inhibitors Useful as Metabolic Modulators
03/20/2008US20080070789 Process for making amlodipine, derivatives thereof, and precursors therefor
03/20/2008US20080070093 aromatic resins having heat and oxidation resistance, high doping ability and high conductivity values, used as electrolytes in high temperature proton exchange-membrane fuel cells
03/20/2008DE69717831C5 Substituierte 2-(2,6-dioxopiperidin-3-yl)-phthalimide und -1-oxoisoindoline und verfahren zur reduzierung des tnf-alpha-spiegels Substituted 2- (2,6-dioxopiperidin-3-yl) -1-oxoisoindoline and -phthalimides and method for reducing the TNF-alpha levels
03/20/2008DE102007037830A1 Indolinsulfonamidverbindungen Indolinsulfonamidverbindungen
03/20/2008DE102006040915A1 New oxindole derivatives useful for treating vasopressin- or oxytocin-dependent diseases
03/20/2008CA2663503A1 Azetidinone derivatives and methods of use thereof
03/20/2008CA2663376A1 N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same
03/20/2008CA2663280A1 Diaryl piperidine compounds as calcium channel blockers
03/20/2008CA2663189A1 Benzimidazolone derivatives
03/20/2008CA2663113A1 Nicotinic acid derivatives as modulators of metabotropic glutanate receptors
03/20/2008CA2662902A1 Kinase inhibitor compounds
03/20/2008CA2662409A1 5-phenyl-nicotinamide derivatives
03/20/2008CA2662099A1 Pyridine- and quinoline-pyrimidine-derivatives
03/20/2008CA2661951A1 Substituted amides, method of making, and method of use thereof
03/20/2008CA2661938A1 Pyrimidines derivatives and their use as kinase inhibitors
03/20/2008CA2661654A1 Certain substituted amides, method of making, and method of use thereof
03/19/2008EP1900735A1 Pyridazinyl amine derivatives, the use thereof in the preparation of picorna virus inhibitors
03/19/2008EP1900733A1 Process for production of 4(3h)-quinazolinone derivative
03/19/2008EP1900732A1 Novel nitrogenated heterocyclic compound and salt thereof
03/19/2008EP1900731A1 N-(1-Phthalazin-1-yl-piperidin-4-yl)-amides as EP2-receptor modulators
03/19/2008EP1900730A1 Process for the preparation of anthranilamide derivatives
03/19/2008EP1900727A1 Aminopyridine derivatives as kinase inhibitors
03/19/2008EP1900726A1 Heterocyclic thioesters
03/19/2008EP1900721A1 Substituted cyclic compound, its preparation process and its medical use
03/19/2008EP1899329A1 Pyrimidine-substituted benzimidazole derivatives as protein kinase inhibitors