Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
04/2008
04/08/2008US7354925 Alpha aryl or heteroaryl methyl beta piperidino propanamide compounds as ORL1-receptor antagonists
04/08/2008US7354923 Piperazine melanocortin-specific compounds
04/08/2008CA2337886C Pharmaceutical compositions comprising hydroxylansoprazole and uses thereof
04/08/2008CA2260909C Intestinal absorption of nicotine to treat nicotine responsive conditions
04/08/2008CA2232663C At1-receptor antagonists for preventing and treating postischemic renal failure and for protecting ischemic kidneys
04/08/2008CA2188924C Arylpiperidine and arylpiperazine derivatives and drugs containing the same
04/08/2008CA2187541C Benzoxazepine derivatives, salts thereof, and drugs containing the same
04/03/2008WO2008039489A2 5-substituted quinazolinone derivatives as antitumor agents
04/03/2008WO2008038765A1 Optical information recording medium and azo metal complex dye
04/03/2008WO2008038600A1 1,4-benzodiazepine derivative, pharmaceutical composition comprising the same, and use of the same for medical purposes
04/03/2008WO2008038122A2 Processes for the preparation of 7-substituted 3,3-dimethyl-4-amino-piperidino-quinolone carboxylic acid derivatives
04/03/2008WO2008038011A1 Pyrimidine derivatives as aurora a and aurora b inhibitors
04/03/2008WO2008037789A1 Fungicide n-cycloalkyl-carboxamide, thiocarboxamide and n-substituted-carboximidamide derivatives
04/03/2008WO2008037784A1 Quinolinone derivatives
04/03/2008WO2008037681A1 5-{2-[4-(2-methyl-5-quinolinyl)-l-piperidinyl] ethyl} quinolinone derivatives as 5ht1a receptor modulators for treating sexual dysfunction, cognition impairement, psychotic disorders, anxiety, depression, etc.
04/03/2008WO2008037626A1 Quinoline derivatives with 5-ht-binding properties
04/03/2008WO2008019279A3 Synthesis of piperazines, piperidines and related compounds
04/03/2008WO2008018639A3 Glycine transporter inhibitor
04/03/2008WO2008016883A3 Inhibitors of plasma kallikrein
04/03/2008WO2008014291A3 Compounds and compositions as hedgehog signaling pathway modulators
04/03/2008WO2008008776A3 Hepatitis c virus inhibitors
04/03/2008WO2007135131A9 Substituted pyrazinone derivatives for use as a medicine
04/03/2008WO2007102127A3 New amines
04/03/2008WO2007070359A3 Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof
04/03/2008WO2007015923A8 Benzimidazoles useful as inhibitors of protein kinases
04/03/2008WO2006114666A8 SUBSTITUTED ARYL 1,4-PYRAZlNE DERIVATIVES
04/03/2008US20080081908 Use of metal complex compounds as oxidation catalysts
04/03/2008US20080081907 5-HT5A serotonin receptor activity; such as (5-Methyl-furan-2-ylmethyl)-(5-phenoxymethyl-quinolin-2-yl)-amine; anxiety, depression, sleep disorders, schizophrenia
04/03/2008US20080081825 5-((2,4-difluorophenyl) {[(1-methyl-4-piperidinyl)oxy]imino}methyl)-1-(2,6-dimethylphenyl)-2(1H)-pyridinone; p38 MAP kinase and tumor necrosis factor inhibitor; inflammatory cytokines or chemokine, respiratory diseases, cardiovascular diseases and bone diseases
04/03/2008US20080081824 Substituted piperidines as modulators of chemokine receptor activity
04/03/2008US20080081817 7-(3-ethoxybenzyl)-4-[4-[[trans-4-[[N-(2-methoxyethyl)-N-(tert-butyl)amino]methyl]cyclohexyl]carbonyl]piperazin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine; small-conductance calcium activated potassium channel (SK) blocking agent; gastrointestinal, central nervous system disorders, myotonic muscular dystrophy
04/03/2008US20080081814 Carbonyl Compounds Which Can be Used as Inhibitors of Coagulation Factor Xa
04/03/2008US20080081813 Lipid Lowering Biphenylcarboxamides
04/03/2008US20080081810 rac-6-chloro-3-(3-chloro-benzyl)-3-(3-isopropoxy-phenylamino)-1,3-dihydro-indol-2-one; murine double minute (MDM2 ) oncogene inhibitor; feedback control loop of p53 mutant cells; inhibit the interaction between p53 and MDM2 proteins
04/03/2008US20080081807 Arylphenyl-substituted cyclic keto-enols
04/03/2008US20080081803 Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity
04/03/2008US20080081802 Thiazolyl-Dihydro-Indazole
04/03/2008CA2664342A1 New chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors
04/03/2008CA2664031A1 Quinoline derivatives with 5-ht-binding properties
04/03/2008CA2663731A1 5-substituted quinazolinone derivatives and compositions comprising and methods of using the same
04/03/2008CA2660377A1 Quinolinone derivatives
04/02/2008EP1905769A1 Heterocycle-substituted benzimidazole derivative
04/02/2008EP1905765A1 6-arylamino-5-cyano-4-pyrimidinone as PDE9A-inhibitors
04/02/2008EP1905762A1 Pyrazolone derivative
04/02/2008EP1904480A2 Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one lactic acid salts
04/02/2008EP1904479A2 Novel 2,4-dianilinopyrimidine derivatives, the preparation thereof, their use as medicaments, pharmaceutical compositions and, in particular, as ikk inhibitors
04/02/2008EP1904478A1 Acid addition salts of n-ethyl-n'-[2-methoxy-4-(5-methyl-4-{[(1s)-1-pyridin-3-ylbutyl]amino}pyrimidin- 2-yl)phenyl]urea and uses thereof
04/02/2008EP1904477A1 Indol-3-carbonyl-spiro-piperidine derivatives as v1a receptor antagonists
04/02/2008EP1904476A1 Heteroaryl-substituted amides comprising an unsaturated or cyclic linker group, and their use as pharmaceuticals
04/02/2008EP1904475A1 N-thio-anthranilamid compounds and their use as pesticides
04/02/2008EP1904474A1 New pyridine analogues
04/02/2008EP1904473A1 Benzoheterocyclylethylcarboxamide derivatives
04/02/2008EP1904461A2 Cyclic anilinopyridinotriazines as gsk-3 inhibitors
04/02/2008EP1904457A2 Compositions and methods for inhibition of the jak pathway
04/02/2008EP1904454A2 Process for the production of intermadiates for the preparation of tricyclic benzimidazoles
04/02/2008EP1904452A2 Histone deacetylase inhibitors
04/02/2008EP1904450A1 Pyrazole-4- carboxamide derivatives as microbiocides
04/02/2008EP1904442A1 Histamine h3 receptor agents, preparation and therapeutic uses
04/02/2008EP1904064A2 Omeprazole form b
04/02/2008EP1709030B1 Indolylmaleimide derivatives
04/02/2008EP1232147B1 Triazoles as farnesyl transferase inhibitors
04/02/2008EP1129088B1 Crystalline form of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole
04/02/2008CN101155807A Compounds having tie2 (tek) inhibitory activity
04/02/2008CN101155801A Process for preparing 2, 3-disubstituted indoles
04/02/2008CN101155800A Pyrazolylaminopyridine derivatives useful as kinase inhibitors
04/02/2008CN101155799A Pyrimidine inhibitors of kinases
04/02/2008CN101155798A Vla-4拮抗剂 Vla-4 antagonists
04/02/2008CN101155797A 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
04/02/2008CN101155796A Imidazole derivatives
04/02/2008CN101155789A 1h-quinaz0line-2,4-diones and their use as ampa-receptor ligands
04/02/2008CN101155786A N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
04/02/2008CN101155784A Cis-2,4,5-triaryl-imidazolines and their use as anti-cancer medicaments
04/02/2008CN101155783A Pyrazoles
04/02/2008CN101155780A Hydroxamates as histone deacetylase inhibitors and pharmaceutical formulations containing them
04/02/2008CN101153022A Isoquinolinium compound, producing method and application of its salt
04/02/2008CN101153021A Isoquinolinium compound, producing method and application of its salt
04/02/2008CN100378100C Pyrazolo(4,3-d)pyrimidine derivatives
04/02/2008CN100378094C Novel 2-pyridinecarboxamide derivatives
04/02/2008CN100378093C Method for preparing optical purity or optically concentrated sulfoxide compounds comprising amorphous esomeprazole and its salts
04/02/2008CN100378092C Biphenyl derivatives
04/02/2008CN100378082C Pyrimidine compounds and pests controlling composition containing the same
04/02/2008CN100378076C Pyridine carboxamide derivatives and their use as pesticides
04/02/2008CN100378075C Aniline derivative using as phosphodiesterase 4 inhibitor
04/02/2008CN100378074C 2-,3-4- or 5-substituted-n1-(benzensulfonyl)indoles and their use in therapy
04/02/2008CN100378063C Novel compounds and medicinal use thereof
04/02/2008CN100377709C Use of acceptor tyrosine kinases inhibitor and related detecting method
04/02/2008CN100377645C Substituted arylpyrazoles as parasiticidal agents
04/01/2008US7351828 Benzimidazoles that are useful in treating sexual dysfunction
04/01/2008US7351826 Aryl acid pyrimidinyl methyl amides, pyridazinyl methyl amides and related compounds
04/01/2008US7351825 4-[5-((1S,2R)-1-Carboxy-2-phenyl-cyclopropylsulfamoyl)-thiophen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; aggrecanase and matrix metalloproteinase (with zinc in the catalytic active center) (MMP) inhibitor; antiarthritic agent: osteoarthritis, rheumatoid arthritis
04/01/2008US7351822 Serine protease inhibitors
04/01/2008US7351807 Cyanine-sulfenates for dual phototherapy
04/01/2008US7351733 Tetrahydrocarbazole derivatives and their pharmaceutical use
04/01/2008US7351720 chemokine receptor (CCR) inhibitors for treating allergic or inflammatory diseases such as asthma or rheumatoid arthritis, multiple sclerosis, inflammatory bowel diseases; 2-((p-fluorobenzyl)piperidinylmethyl)cyclohexylureas of given formula
04/01/2008US7351719 Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
04/01/2008US7351712 Inhibitors of the FAK (focal adhesion kinase) protein tyrosine kinases, antiproliferative, antitumor; for example 5-{4-[(1-Hydroxy-cyclopentylmethyl)-amino]-5-trifluoromethyl-pyrimidin-2-ylamino}-1,3-dihydro-indol-2-one
04/01/2008US7351711 Tricyclic indanyls as integrin inhibitors
04/01/2008US7351706 Indol-3-yl-carbonyl-spiro-piperidine derivatives
04/01/2008US7351704 Indazole-carboxamide compounds as 5-HT4 receptor agonists
04/01/2008US7351700 4-(2-Hexylsulfanyl-6-methyl-pyrimidin-4-ylmethyl)-morpholine; antidepressant, anxiolytic agent, cognition activator; epilepsy, schizophrenia, spasticity and skeletal muscle rigidity, spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis, neuropathic pain