Patents
Sitemap › C07 - Organic chemistry › C07D - Heterocyclic compounds › C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
11/2008
11/13/2008US20080280918 phosphodiesterase enzyme inhibitor; 4-[(3-chlorophenyl)amino]-2-ethyl-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one; potent antiinflammatory agent; asthma, atopic dermatitis, psoriasis, chronic obstructive pulmonary disease, rheumatoid arthritis, irritable bowel disease
11/13/2008US20080280911 Cinnoline Compounds as Inhibitors of Phosphodiesterase Type IV (Pde4)
11/13/2008US20080280909 New phenylalanine derivatives
11/13/2008US20080280905 Urea antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
11/13/2008US20080280904 N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors
11/13/2008US20080280903 antiapoptosis agents such as 1-[2-Methoxyimino-2-(4-pyrrolidin-1-yl-phenyl)-ethyl]-quinolinium bromide, used for cytoprotection or for side effect reduction of anticarcinogenic agents
11/13/2008US20080280902 Inhibitors of Checkpoint Kinases
11/13/2008US20080280898 5-Bromo-1'-[(3-methyl-1H-inden-2-yl)carbonyl]spiro[indole-3,4'-piperidin]-2(1H); vasopressin receptor antagonist; antidepressant, anxiolytic agent; dysmenorrhea, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, obsessive compulsive disorder
11/13/2008US20080280895 5-Amino-4-Hydroxy-7-(1H-Indolmethyl)-8-Methylnonamide Derivatives as Renin Inhibitors for the Treatment of Hypertension
11/13/2008US20080280891 effective against a broad range of cancers, especially leukemia, non-small cell lung and colon; (6-chloropyridin-3-yl)-[3-hydroxy-5-(1H-indol-4-yl)-phenyl]-methanone; antimitotic agents that can block cell cycle progression
11/13/2008US20080280889 Cancer; N,N-dimethyl-5-phenyl-6-(4-{[4-(5-pyridin-2-yl-1H-pyrazol-3-yl)piperidin-1-yl]methyl}phenyl) pyridazin-3-amine;; serine/threonine kinase (Akt) suppression; increased cellular potency or solubility, enhanced pharmacokinetic properties
11/13/2008US20080280887 Selected Cgrp-Antagonists, Processes for Preparing Them and Their Use as Pharmaceutical Compositions
11/13/2008US20080280873 Biaryl Substituted Pyrazinones as Sodium Channel Blockers
11/13/2008US20080280868 Pyridine Derivatives and Their Use as Cb2 Receptor Modulators
11/13/2008US20080280857 ligands for Calcitonin gene related peptide; azepinone ligands; migranes; N-[5-(2,3-Difluorophenyl)-1-(2-methoxyethyl)-2-oxopiperidin-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
11/13/2008CA2686382A1 Phenylaminopyrimidine derivatives and compositions thereof as c-kit and pdgfr kinase inhibitors
11/13/2008CA2686379A1 Phenylaminopyrimidine derivatives and compositions thereof as c-kit and pdgfr kinase inhibitors
11/13/2008CA2685876A1 Thiazoles and pyrazoles useful as kinase inhibitors
11/13/2008CA2685546A1 Organic compounds
11/13/2008CA2683821A1 Heterocyclic compounds and their use as pesticides
11/13/2008CA2680803A1 Derivatives of the aminated hydroxyquinoline class for treating cancers
11/13/2008CA2674831A1 5,6-ring annulated indole derivatives and methods of use thereof
11/12/2008EP1990337A1 Quinazoline derivatives,preparation methods and uses thereof
11/12/2008EP1990335A1 17 beta hsd type 5 inhibitor
11/12/2008EP1989196A2 Melanocortin type 4 receptor agonist piperidinoylpyrrolidines
11/12/2008EP1989195A1 Phosphodiesterase 10 inhibitors
11/12/2008EP1989188A1 Therapeutic piperazines as pde4 inhibitors
11/12/2008EP1989185A1 Therapeutic compounds
11/12/2008EP1988777A2 Pyrazoles for the treatment of obesity and other cns disorders
11/12/2008EP1863791B1 2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl-piperidines used as cgrp antagonists
11/12/2008EP1751138B9 Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders
11/12/2008EP1732918B1 Novel pyrrolidine-3,4-dicarboxamide derivatives
11/12/2008EP1727808B1 Biaryl amino acids and their use in dna binding oligomers
11/12/2008EP1705989B1 Substituted arylpyrazoles as parasiticidal agents
11/12/2008EP1703905B1 Indole derivatives and use thereof as kinase inhibitors in particular ikk2 inhibitors
11/12/2008EP1644340B1 N-[({'4-substituted piperazine-1-yl}sulfonylmethyl)alkyl]-n-hydroxyformamide compounds as metalloproteinase inhibitors
11/12/2008EP1641780B1 Processes for the preparation of 1- [(benzoimidazole-1yl) quinolin-8-yl] piperidin-4-ylamine derivatives
11/12/2008EP1606282B1 Phenyl- and pyridylpipereidinye-derivatives as modulators of glucose metabolism
11/12/2008EP1532117B1 Multi-substituded imidazolines and method of use thereof
11/12/2008EP1445271B1 Polyisocyanate composition having allophanate group and high-solid coating material
11/12/2008EP1409468B1 Guanidinobenzamides as mc4-r agonists
11/12/2008EP1343503B1 Heteroaryl urea neuropeptide y y5 receptor antagonists
11/12/2008EP1315490B1 A method for treating allergies using substituted pyrazoles
11/12/2008CN101304990A Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for the production thereof
11/12/2008CN101304989A Carbocyclic fused cyclic amines as inhibitors of the coagulation factor XA
11/12/2008CN101304988A Process for production of 2-(4-methyl-2-phenylpiperazin-1-yl)pyridine-3-methanol
11/12/2008CN101304987A Aminophenylsulfonamide derivatives as HIV protease inhibitor
11/12/2008CN101304981A P2x7 receptor antagonists and methods of use
11/12/2008CN101304975A P2X7 receptor antagonists and uses thereof
11/12/2008CN101304974A Pyrazole derivatives and their medical use
11/12/2008CN101304973A Methods of modulating neurotrophin-mediated activity
11/12/2008CN101304743A Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration
11/12/2008CN101302194A Synthetic method of polysubstituted chinoline compound
11/12/2008CN101302184A Indoline sulfanilamide compound
11/12/2008CN101302182A Virus polymerase inhibitors
11/12/2008CN100432070C Novel sulfamides and their use as endothelin receptor antagonists
11/12/2008CN100432055C Tricyclic protein kinase inhibitors
11/11/2008US7450293 Electrochromic salts, solutions, and devices
11/11/2008US7449585 1,2-dihydro-2-(4-trifluoromethylphenyl)-6-(3-trifluoromethyl-2-pyridinyl)-3H-indazol-3-one; capsaicin receptor ; analgesic, antiinflammatory, hypotensive agent; rheumatoid arthritis, osteoarthritis, headache, migraine, cancer and central nervous system pain, irritable bowel syndrome
11/11/2008US7449583 Process for the preparation of 4-(8-chloro-5 6-dihydro-11h-benzo-(5 6)-cyclohepta-(1 2b)-pyridin-11-ylidene-1-piperidiniecarboxylic acid ethyl ester (loratadine)
11/11/2008US7449576 potent antagonists of the CCR1 receptor; inflammation; (5-Chloro-2-piperazin-1-yl-phenyl)-phenyl-methanone
11/11/2008US7449489 e.g. isopropyl [({2-[5-[2-(2-azabicyclo[2.2.2]oct-2-yl)- 1,1-dimethyl-2-oxoethyl]-2-(3,5-dimethylphenyl)-1H-indol-3-yl]propyl }amino)(3-pyridin-4-ylpyrrolidin-1-yl)methylene]carbamate; gonadotrophin releasing hormone antagonists; anticarcinogenic agent; breast, prostate, uretus cancer
11/11/2008US7449484 angiogenesis inhibitor; Tie2 receptor kinase inhibitors; 2-tert-Butyl-4-naphthalen-2-yl-5-pyridin-4-yl-imidazole;2-tert-Butyl-4-(6-Ethoxynaphthalen-2-yl)-5-pyridin-4-yl-imidazole;4-(2-tert-Butyl-5-(6-methoxy-naphthalen-2-yl)-3H-imidazol-4-yl)-pyridine; etc.
11/11/2008US7449480 Small molecule inhibitors of HER2 expression
11/11/2008US7449479 Hepatitis C virus inhibitors
11/11/2008US7449477 7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)
11/11/2008US7449474 Tri-substituted ureas as cytokine inhibitors
11/11/2008US7449471 5-phenylpyrimidines, their preparation, compositions comprising them and their use
11/11/2008US7449466 Cyclic aminophenyl sulfamate derivative
11/11/2008US7449465 glycogen synthase kinase 3 alpha and 3 beta inhibitors; improved phanrmacological activity, potency, selectivity, solubility, permeability, metabolic stability; bipolar disorder; Alzheimer's disease; type II diabetes, neuropathic pain; depression; inflammatory diseases
11/11/2008US7449464 4-{3-[4-(6-Chlorobenzothiazol-2-yl)-1,4-diazepan-1-ylcarbonyl]benzyl}-1(2H)-phthalazinone; Cancer, BRCA deficient
11/11/2008US7449462 2-{4-[4-(2-Ethyl-phenyl)-5-methyl-4H-[1,2,4]triazol-3-yl]-piperidin-1-yl}-pyrimidine; more potent, longer duration of action, broader range of activity, more stable, fewer side effects, selectivity; anxiety, cardiovascular disease, dysmenorrhoea, endometriosis, emesis, inflammation, sexual disorders
11/11/2008US7449460 3-Quinolinecarbonitrile protein kinase inhibitors
11/11/2008US7449459 Inhibitors of soluble adenylate cyclase
11/11/2008US7449457 Substituted heterocyclic carboxamides with antithrombotic activity
11/11/2008US7449456 signal transducer and activator of transcription-6 inhibitors; asthma, COPD, respiratory, inflammatory and allergic diseases; compounds have less suppressive effect on immunological functions; 4-[(2,5 -difluorobenzyl) amino]-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5 -carboxamide
11/06/2008WO2008134693A1 Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme
11/06/2008WO2008133973A1 Therapeutic agents useful for treating pain
11/06/2008WO2008133949A1 Analogues of cilostazol
11/06/2008WO2008133900A1 Quaternary ammonium compounds useful as muscarinic receptor antagonists
11/06/2008WO2008133896A2 Dual-acting antihypertensive agents
11/06/2008WO2008133155A1 Bicyclic heterocyclic compound
11/06/2008WO2008132679A1 Bridged six-membered ring compounds
11/06/2008WO2008132600A2 Trpv1 antagonists and uses thereof
11/06/2008WO2008132505A1 N' - (phenyl) -n- (morpholin-4-yl-pyridin-2-yl) -pyrimidine-2, 4-diamine derivatives as ephb4 kinase inhibitors for the treatment of proliferative conditions
11/06/2008WO2008132502A1 Pyrazolyl-amino-substituted pyrimidines and their use for the treatment of cancer
11/06/2008WO2008132211A1 Amino-quinazolinone derivatives for use as radiotracers and imaging agents
11/06/2008WO2008131972A1 Arylmethylen substituted n-acyl-gamma-aminoalcohols
11/06/2008WO2008131860A2 Pyridonecarboxamides crop protection agents containing the same method for production and use thereof
11/06/2008WO2008131779A1 Isoquinolinone derivatives as nk3 antagonists
11/06/2008WO2008108517A3 Piperazinyl-propyl-pyrazole derivatives as dopamine d4 receptor antagonists, and pharmaceutical compositions containing the same
11/06/2008WO2008106594A3 Inhibitors of nucleophosmin (npm) and methods for inducing apoptosis
11/06/2008WO2008100456A3 Functionally selective alpha2c adrenoreceptor agonists
11/06/2008WO2008079291A3 Substituted heterocycles and methods of use
11/06/2008WO2008076046A8 Novel 2-amino-5, 5-diaryl-imidazol-4-ones
11/06/2008WO2008073933A3 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use
11/06/2008WO2008072053A3 Substituted arylpyrazoles
11/06/2008WO2008030455A3 Small molecule inhibitors of toll-like receptor 9
11/06/2008WO2008024977A3 Isoquinoline, quinazoline and phthalazine derivatives
11/06/2008WO2007136605A3 Aryl-fused spirocyclic compounds
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