Patents
Patents for C07D 401 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom (107,979)
11/2008
11/26/2008CN100436452C Pyrazole compounds useful as protein kinase inhibitors
11/26/2008CN100436450C Novel triarylimidazoles
11/26/2008CN100436449C Preparation of pharmaceutical salts of 4((z)-(4-bromophenyl)(ethoxyimino)methyl)-1'-((2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl)-4'-methyl-1,4'bipiperidine as ccr5-antagonists for the treatment of aid
11/26/2008CN100436448C Bicyclic indolyl derivatives and methods of their use as serotonergic agents
11/26/2008CN100436447C Compounds possessing neuronal activity
11/26/2008CN100436446C Ester derivatives of a decahydroisoquinoline-3-carboxylic acid as analgestics
11/26/2008CN100436445C Pyrazole derivative
11/26/2008CN100436425C Fused imidazolium derivatives
11/26/2008CN100436421C Dual binding site acetylcholinesterase inhibitors for the treatment of alzheimer's disease
11/25/2008US7456289 Anti-tumor compounds
11/25/2008US7456288 Heterocyclic compounds and methods of making and using thereof
11/25/2008US7456287 Tipifarnib (R115777) from amination of 6-[chloro(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone with chiral (S)-(-)-1-(4-methoxyphenyl)ethylamine and acidic conversion of claimed intermediate to the primary amine
11/25/2008US7456283 an N-phenyl-4-(4-methyl-piperazin-1-ylmethyl)-benzamide claimed intermediate easily prepared by amidation of the aniline and the benzoic acid; reaction with a 2-aminopyrimidine to produce antitumor tyrosine kinase inhibitor
11/25/2008US7456279 antibiotic 7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid by amination of the borone ester chelate of the 7-fluoro-dihydro-quinolone carboxylic acid with (5-Methyl-piperidin-3-yl)-carbamic acid tert-butyl ester and then deprotecting by hydrolysis
11/25/2008US7456211 Enzyme inhibitors as bactericides for infections and as enzyme inhibitors
11/25/2008US7456208 CCK-1 receptor modulators
11/25/2008US7456202 Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules
11/25/2008US7456201 Such as N-{5-[1-(4-tert-butylphenyl)-3-pyridin-2-yl-1H-pyrazol-5-yl]pentanoyl}tyrosinamide; useful for the treatment of mammalian infertility
11/25/2008US7456198 Useful in the treatment of chronic and acute pain.
11/25/2008US7456197 Such as 1-(2,3-dihydroxypropyl)-2,4,6-trimethylpyridinium hexafluorophosphate; transfecting eukaryotic cells
11/25/2008US7456196 Alzheimer's disease; antihistamine; attention deficit disorder; hyperactivity; bipolar disorder; cognition activators; psychological disorder; anticancer agent; antidepressants; antiepileptic agents; gastrointestinal disorder; analgesics; 6-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-2-(3-pyridinyl)quinoline
11/25/2008US7456195 Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants
11/25/2008US7456190 autoimmune disease; antiinflammatory agents; bone disorders; central nervous system disorders; cardiovascular disorders; Alzheimer's disease; antihistamines; antiallergens
11/25/2008US7456185 2-amino-6-phenoxy-substituted quinazoline derivatives; treating arthritis, Crohn's disease, Alzeihmer's disease, adult respiratory distress syndrome, chronic obstructive pulmonary disease, asthma, stroke, sepsis, myocardial infarction, and spondylitis
11/25/2008US7456183 Melanocortin-4 receptor agonists; obesity, type II diabetes; such as N-(2-(2-(2,4-dichlorophenyl)ethyl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl) -3-methyl-N'-(2,6,6-trimethylbicyclo(3.1.1)hept-3yl)piperazine-1-carboximidamide
11/25/2008US7456182 Phenylpiperazines
11/25/2008US7456181 Aripiprazole crystalline forms
11/25/2008US7456176 Benzotriazine inhibitors of kinases
11/25/2008US7456175 For treatment and/or prevention of diseases which are associated with the modulation of H3 receptors; treatment of obesity; N-[2-(4-ethyl-piperazin-1-yl)-pyridin-4-yl]-propionamide, 1-[2-(4-ethyl-piperazin-1-yl)-pyridin-4-yl]-3-propyl-urea
11/25/2008US7456172 Succinoylamino benzodiazepines as inhibitors of Aβ protein production
11/25/2008US7456169 Heterocyclic kinase inhibitors
11/25/2008US7456164 Useful for treatment of H3-related diseases such as neurologic disorders, or inflammatory, respiratory and allergic diseases, disorders and conditions; for example, 4-[4-(1-isopropylpiperidin-4-yloxy)phenyl]tetrahydropyran-4-carbonitrile; well absorbed from gastrointestinal tract, metabolically stable
11/25/2008CA2376760C Quinolinecarboxylic acid derivative or salts thereof
11/25/2008CA2318579C Nitrogen-containing heterocyclic compounds and medicaments containing the compounds
11/25/2008CA2275635C Pesticidal 1-arylpyrazoles
11/25/2008CA2271136C Novel pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient
11/25/2008CA2224369C Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use
11/25/2008CA2211749C Biphenyl-substituted triazines as light stabilizer
11/20/2008WO2008141312A1 ((phenyl)imidazolyl)methylheteroaryl compounds
11/20/2008WO2008141227A1 Novel peptide inhibitors of hepatitis c virus replication
11/20/2008WO2008141119A2 Modulators of cftr
11/20/2008WO2008141020A1 2-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-3-phenyl pyrazines and pyridines and 3-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-2-phenyl pyridines as 5-ht7 receptor antagonists
11/20/2008WO2008140895A1 Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
11/20/2008WO2008140850A1 Solid forms of a raf kinase inhibitor
11/20/2008WO2008140239A1 Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same
11/20/2008WO2008140198A1 Novel carbamoyloxy arylalkanoyl arylpiperazine compound, pharmaceutical compositions comprising the compound and method for treating pain, anxiety and depression by administering the compound
11/20/2008WO2008140111A1 One-pot production process for cinnamide derivative
11/20/2008WO2008140099A1 Tetrazoyloxime derivative and plant disease control agent
11/20/2008WO2008140066A2 Pyridone derivatives as p38a mapk inhibitors
11/20/2008WO2008139941A1 Substituted imidazole compound and use thereof
11/20/2008WO2008139894A1 Nitrogenated aromatic 6-membered ring derivative, and pharmaceutical agent comprising the same
11/20/2008WO2008139288A2 Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials
11/20/2008WO2008139152A1 N-oxide-containing pharmaceutical compounds
11/20/2008WO2008138992A1 Fungicides phenyl-pyrimdinyl-amino derivatives
11/20/2008WO2008138939A1 Pyrazolone derivatives as pde4 inhibitors
11/20/2008WO2008138920A1 Dihydroquinone and dihydronaphthridine inhibitors of jnk
11/20/2008WO2008138918A1 Mono-hydrochloric salts of an inhibitor of histone deacetylase
11/20/2008WO2008138754A2 New solid forms of fxa inhibitors
11/20/2008WO2008138733A1 Oxime ester photoinitiators
11/20/2008WO2008117079B1 Antimicrobial compounds based upon 4-aminoquinoline
11/20/2008WO2008111077A3 Self-assembled polyhedral multimeric chemical structures
11/20/2008WO2007110418A3 Substituted 5-hetaryl-4-aminopyrimidines
11/20/2008WO2007102883A3 Chemical compounds
11/20/2008US20080287682 Substituted benzimidazoles and methods of preparation
11/20/2008US20080287681 Substituted Benzimidazoles and their Use for Inducing Apoptosis
11/20/2008US20080287677 Salts of Aripiprazole
11/20/2008US20080287676 Fused compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor
11/20/2008US20080287674 Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade
11/20/2008US20080287517 Pyrazole Derivatives as Cb1 Modulators
11/20/2008US20080287506 Insecticidal N,N-Di(Heteroarylalkyl) Amine Derivatives
11/20/2008US20080287505 Substituted 2-methyl-2-phenoxy-n-propyl-propionamides as cannabinoid receptor antagonists/inverse agonists useful for treating obesity
11/20/2008US20080287504 Such as N-(4-Fluoro-benzyl)-4-(3-phenyl-indole-1-sulfonyl)-benzamide; Cannabinoid-1 (CB1) receptor; dietetics
11/20/2008US20080287496 1-Oxo- and 1,3-dioxoisoindolines and method of reducing inflammatory cytokine levels
11/20/2008US20080287492 Alkylpyridyl Quinolines as Nk3 Receptor Modulators
11/20/2008US20080287490 Bis-pyridino containing compounds for the use in the treatment of CNS pathologies
11/20/2008US20080287484 Neurotrophin antagonist compositions
11/20/2008US20080287479 Inhibitors of serine palmitoyltransferase
11/20/2008US20080287474 Antiproliferative Pyrimidyl, Fused Pyrimidyl and Pyrimidyl Hydrazones
11/20/2008US20080287461 5-Bromo-2,6-dimethyl-6'-{[4-(trifluoromethoxy)benzyl]oxy}-3,3'-bipyridin-4(1H)-one; 3-Chloro-2,6-dimethyl-5-(5-nonyl-2-pyrimidinyl)-4(1H)-pyridinone; treating maleria causerd by infection with Plasmodium falciparum
11/20/2008US20080287460 New compounds 835
11/20/2008US20080287455 Sulfanyl substituted phenyl methanones
11/20/2008US20080287454 Cxcr4 antagonists
11/20/2008US20080287453 Piperazine Compounds Useful as Antagonists of C-C Chemokines (Ccr2b and Ccr5) for the Treatment of Inflammatory Diseases
11/20/2008US20080287452 Heteroaryl/aryl pyrimidine analogs and their use as agonists of the wnt-beta-catenin cellular messaging system
11/20/2008US20080287449 Aza-tripeptide hepatitis c serine protease inhibitors
11/20/2008US20080287444 Pyrazole compounds useful as protein kinase inhibitors
11/20/2008US20080287440 Novel Antifungal Triazole Derivatives
11/20/2008US20080287438 Agent for preventing or treating neuropathy
11/20/2008US20080287424 e.g. N-[amino(imino)methyl]-2-[2-(4-phenoxyphenyl)-5-phenyl-1H-pyrrol-1-yl]acetamide; beta -amyloid deposits and neurofibrillary tangles; cognition activator, neurodegenerative diseases; Alzheimer's disease, Down's syndrome
11/20/2008US20080287415 Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
11/20/2008US20080287411 Optically active dihydropyridine derivative
11/20/2008US20080287410 Pyrimidine derivatives useful as inhibitors of pkc-theta
11/20/2008US20080287399 Substituted Aminopyridines and Uses Thereof
11/20/2008US20080287396 Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections
11/20/2008US20080286207 Polycyclo Dyes and Use Thereof
11/20/2008CA2687303A1 ((phenyl)imidazolyl)methylheteroaryl compounds
11/20/2008CA2687262A1 One-pot production process for cinnamide derivative
11/20/2008CA2686926A1 Novel carbamoyloxy arylalkanoyl arylpiperazine compound, pharmaceutical compositions comprising the compound and method for treating pain, anxiety and depression by administering the compound
11/20/2008CA2686909A1 Pyrazolone derivatives as pde4 inhibitors
11/20/2008CA2686838A1 Modulators of cftr