Patents
Patents for C07D 257 - Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms (9,612)
10/1999
10/06/1999EP0946501A1 Prevention of loss and restoration of bone mass by certain prostaglandin agonists
10/06/1999CN1230980A Metal ligand containing bleaching compositions
10/06/1999CN1230979A Metal ligand containing bleaching composition
10/06/1999CN1230903A Long-lived homogenous oxidation catalyst
10/05/1999US5962731 Modify lipid metabolism; skin disorders,; autoimmune diseases; fatty acid metabolism; antitumor agents
10/05/1999US5962682 Aryl- and hetaryl-sulfonamide derivatives, their preparation and their use as endothelin antagonists
10/05/1999US5962679 Process for the preparation of 1,4,7,10-tetraaza-cyclododecane-1,4,7-triacetic acid and the derivatives thereof
10/05/1999US5962495 Estrogen sensitive diseases; breast cancer; prostate tumors
09/1999
09/30/1999WO1999048858A2 Aliphatic amino carboxylic and amino phosphonic acids, amino nitriles and amino tetrazoles as cellular rescue agents
09/30/1999CA2325943A1 Aliphatic amino carboxylic and amino phosphonic acids, amino nitriles and amino tetrazoles as cellular rescue agents
09/30/1999CA2267047A1 Derivatives of phenoxy acetic acid and phenoxymethyl tetrazole having antitumor activity
09/28/1999US5958971 Chemical compounds
09/28/1999US5958957 Modulators of molecules with phosphotyrosine recognition units
09/28/1999US5958373 Macrocyclic polyamine ligand forms a polychelate compound with lanthanides, chromium, iron and manganese; useful for diagnostic imaging contrast
09/22/1999CN1229082A Amine compound and its acid addition salt
09/21/1999US5955576 Peptide aldehyde analogs that inhibit thrombin or factor xa; for prevention or treatment of abnormal thrombosis
09/21/1999US5955487 Treating high blood pressure, cardiac insufficiency, glaucoma
09/21/1999US5955463 Antitumor, antiinflammatory, and antiarthritic agents
09/16/1999WO1999046242A1 Cycloalkene derivatives, process for producing the same, and use
09/14/1999US5952377 Fatty acid analogs and prodrugs
09/14/1999US5952375 Compounds and methods for synthesis and therapy
09/14/1999US5952359 Thiazoles and their agricultural compositions
09/10/1999WO1999009000A3 Novel inhibitors of aggrecanase and matrix metalloproteinases for the treatment of arthritis
09/07/1999US5948780 Administering a metalloproteinase inhibitor
09/02/1999WO1998034632A9 Compounds and compositions for delivering active agents
09/01/1999EP0938483A2 Muscarinic antagonists
08/1999
08/31/1999US5945572 Method for producing aryl alkyl hydroperoxides
08/31/1999US5945532 Method for manufacture of cephalosporin and intermediates thereof
08/31/1999US5945450 Naphthalene derivative
08/26/1999WO1999035133A3 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid derivatives as chelating agents
08/26/1999WO1999026909A3 Alpha-hydroxy, -amino and -fluoro derivatives of beta-sulphonyl hydroxamic acids as matrix metalloproteinases inhibitors
08/24/1999US5942493 LH-RH antagonists having improved action
08/19/1999WO1999041231A1 Amidino derivatives and drugs containing the same as the active ingredient
08/19/1999WO1999024394A3 Compounds for the antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid deposition
08/18/1999CN1225922A Metal chelates of substituted polyaminocarboxylic macrocycles and their use in diagnostic imaging
08/17/1999US5939443 Selective β3 adrenergic agonists
08/17/1999US5939442 Modulations of peroxisome proliferator activated receptor-γ, and methods for the use thereof
08/17/1999US5939381 4-(4-(phenoxyacetyl)aminophenyl)butyric acid as a carrier for drug delivery
08/17/1999CA2150610C Benzene derivatives and pharmaceutical composition
08/11/1999EP0934316A1 Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use
08/10/1999US5935907 Phenylacetylene derivatives
08/05/1999WO1999038508A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
08/05/1999CA2319465A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
08/04/1999CN1225088A Carbamoyltetrazolinones and herbicides
08/04/1999CN1224723A Stable and water soluble bis Au(I) complexes and their synthesis
08/03/1999US5932730 Endothelin antagonist
08/03/1999US5932575 Cardiac diseases improving agents
08/03/1999US5932559 Treatment of hyperandrogenic conditions
07/1999
07/29/1999DE19900571A1 New oximino substituted phenyl tetrazolinone derivatives, having fungicidal, insecticidal, acaricidal and nematocidal activity
07/28/1999EP0931057A1 Method for preparing 4-methyl-biphenyl derivatives
07/28/1999CN1223793A Tetrazolinones as herbicides for use in paddy fields
07/27/1999US5929110 Fatty acid analogs and prodrugs
07/22/1999WO1999036393A1 INHIBITORS OF α4 MEDIATED CELL ADHESION
07/22/1999WO1999036384A1 Alkenyldiarylmethane non-nucleoside hiv-1 reverse transcriptase inhibitors
07/22/1999CA2317942A1 Alkenyldiarylmethane non-nucleoside hiv-1 reverse transcriptase inhibitors
07/21/1999CN1223637A Phenylalamine derivatives as integrin inhibitors
07/21/1999CN1223259A Anti-cancer medicine 3,6-dimethyl 1,4-dihydro 1,2,4,5-tetrazine-1,4-dimethyl amides compound and preparation process thereof
07/20/1999US5925753 Reacting 1,4,7,10-tetraazacyclododecane with triethyl orthoformate in presence of an acid catalysts
07/20/1999US5925752 Process for the preparation of macrocyclic chelants and the chelates thereof with paramagnetic metal ions
07/20/1999CA1340657C Modulateurs de la proteine kinase c
07/15/1999WO1999035134A1 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid
07/15/1999WO1999035133A2 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid derivatives as chelating agents
07/15/1999WO1999034797A1 Method for treating multiple sclerosis
07/15/1999CA2317548A1 Method for treating multiple sclerosis
07/13/1999US5922862 Alkylation of 2a,4a,6a,8a-decahydrotetraazacyclopent(fg)acenaphthylene
07/13/1999US5922763 Biphenyl derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
07/13/1999US5922744 Novel compounds, their synthesis, for treating central nervous system disorders, respiratory system disorders and other diseases mediated by tachykinins; example: n2-(2-methoxy-5-tetrazol-1-yl-benzyl)-1-phenylethane-1,2-diami
07/07/1999EP0927166A1 Amides as npy5 receptor antagonists
07/07/1999CN1222147A Process for prepn. of tetraazamacrocycles
07/06/1999US5919787 Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
07/06/1999US5919433 Macrocyclic metal complex carboxylic acids, their use as well as process for their production
07/06/1999US5919432 Polyaminated ligands and metal complexes thereof
07/06/1999US5919431 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production
07/01/1999WO1999032454A1 Nitrogen containing heteroaromatics with ortho-substituted p1's as factor xa inhibitors
07/01/1999WO1999032111A1 INHIBITION OF p38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS
07/01/1999WO1999032106A1 Inhibition of raf kinase using substituted heterocyclic ureas
07/01/1999CA2315720A1 Inhibition of p38 kinase activity using substituted heterocyclic ureas
07/01/1999CA2314401A1 Nitrogen containing heteroaromatics with ortho-substituted p1's as factor xa inhibitors
06/1999
06/24/1999WO1999031078A1 Azulene hydroxamic acid derivatives as metalloprotein inhibitors
06/24/1999WO1999031075A1 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
06/24/1999WO1999031074A2 ((cyclo)alkyl substituted)-.gamma.-aminobutyric acid derivatives (=gaba analogues), their preparation and their use in the treatment of neurological disorders
06/24/1999WO1999031065A1 N-benzyl-3-indenylacetamides derivatives for treating neoplasia
06/24/1999WO1999031061A1 Integrin receptor antagonists
06/24/1999WO1999031057A1 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders
06/24/1999CA2313239A1 Azulene hydroxamic acid derivatives as metalloprotein inhibitors
06/23/1999EP0923635A2 Metal ligand containing bleaching compositions
06/22/1999US5914233 Screening assay for the identification of agents which alter expression of PTH-rP
06/17/1999WO1999029693A1 Imidazonaphthyridines and their use in inducing cytokine biosynthesis
06/17/1999WO1999029674A1 Retinoic acid mimetic anilides
06/17/1999CA2312720A1 Retinoic acid mimetic anilides
06/16/1999EP0922702A1 Azulene derivatives and pharmaceutical compositions containing them
06/16/1999EP0922700A1 Metal chelates of macrocyclic polyaminocarboxylic derivatives and their use for the diagnostic imaging
06/16/1999EP0684830B1 Inhibitors of thrombosis
06/15/1999US5912352 Catalytic reduction of hydrazide to hydrazine derivative in presence of complex hydride; acyl migration; hydrogenation; catalyst selectivity
06/15/1999US5912243 Novel compounds for controlling nematodes, insect or acarid pests
06/10/1999CA2254261A1 Metallic chelates of macrocyclic polyaminocarboxylic derivatives and their application to diagnostic imagery
06/03/1999WO1999026909A2 Alpha-hydroxy, -amino and -fluoro derivatives of beta-sulphonyl hydroxamic acids as matrix metalloproteinases inhibitors
06/03/1999WO1999010312B1 N-alkanoylphenylalanine derivatives
06/03/1999CA2310401A1 Alpha-hydroxy, -amino and -halo derivatives of beta-sulfone hydroxamates as matrix metalloproteinase inhibitors
06/02/1999EP0919544A1 Compounds useful for treating allergic and inflammatory diseases
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