Patents
Patents for C07D 257 - Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms (9,612)
01/1999
01/19/1999US5861428 Alleviation of osteoarthritis, rheumatoid arthritis, septic arthritis, periodontal disease, corneal ulceration, proteinuria, aneurysmal aortic disease, dystrophobic epidermolysis bullosa, inflammation, osteopenias, tempero
01/19/1999US5861427 Substituted 4-biarylbutyric acid derivatives as matrix metalloprotease inhibitors
01/19/1999CA1340325C Tetrazole intermediates to antihypertensive compounds
01/14/1999WO1999001459A1 Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
01/14/1999WO1999001421A1 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors
01/14/1999WO1999001161A1 Perfluoroalkylated oligomer compounds, process for preparing the same and their use in nmr diagnosis
01/14/1999CA2290509A1 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors
01/13/1999EP0889881A1 New triazoles as therapeutic agents for fungal infections
01/12/1999US5859052 Treating lentivirus infections, especially human immunodeficiency virus
01/12/1999US5859047 Antiarthritic agents, nervous system disorders
01/12/1999US5859025 Fluoroalkyl- and fluoroalkoxy-substituted heterocyclic bradykinin antagonists, process for their preparation, and their use
01/07/1999EP0888341A1 Novel sulphur derivatives comprising an amide bond, method for preparing same, use thereof as drugs, and pharmaceutical compositions containing such derivatives
01/07/1999EP0888299A1 Sulphur derivatives with a retroamide bond as endothelin-converting enzyme inhibitors
01/07/1999EP0888278A1 Antidiabetic agents
01/05/1999US5856502 Method for manufacture of cephalosporin and intermediates thereof
01/05/1999CA2005880C Macrocyclic aminophosphonic acid complexes, their preparation formulations and use
12/1998
12/29/1998US5854277 Thiophenebutanoic acid derivatives as matrix metalloprotease inhibitors
12/29/1998US5854251 Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
12/29/1998US5853428 Metal ligand containing bleaching compositions
12/29/1998CA2036427C Acyl compounds
12/24/1998DE19722846A1 Leukotrien-B¶4¶-Derivate, insbesondere 7-Methylcyclohexyl-LTB¶4¶-Antagonisten Leukotriene B¶4¶ derivatives, in particular 7-methylcyclohexyl-LTB¶4¶ antagonists
12/23/1998WO1998057937A2 Inhibitors of factor xa with a neutral p1 specificity group
12/23/1998WO1998057910A2 Cyclooxygenase-i selective inhibitors and the use thereof as analgesic, antiinflammatory and antiarthritic agents
12/23/1998EP0885202A1 Polychelants, their complexes with metal ions, their preparation and their uses
12/23/1998CN1202882A New LH-RH antigonists with improved effectiveness
12/23/1998CA2290982A1 Inhibitors of factor xa with a neutral p1 specificity group
12/17/1998WO1998056791A1 A PROCESS FOR THE PREPARATION OF 5H,9bH-2a, 4a,7,9a-OCTAHYDROTETRAAZACYCLOOCTA [cd]PENTALENE
12/17/1998WO1998056776A1 A process for the preparation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid and the derivatives thereof
12/17/1998WO1998056775A1 A process for the preparation of macrocyclic chelants and the chelates thereof with paramagnetic metal ions
12/16/1998EP0883610A1 Process for preparing 1,4,7,10-tetraazacyclododecane and its derivatives
12/16/1998EP0664791B1 Process for the preparation of oxime derivatives, certain intermediates and the use of the oxime derivatives as fungicides
12/16/1998CN1202107A Selective 'beta'3 adrenergic agonists
12/16/1998CN1202106A Selective 'beta'3 adrenergic agonists
12/15/1998US5849911 Antivirally active heterocyclic azahexane derivatives
12/10/1998WO1998055467A1 Production of mono and 1,7-bis-n-hydroxyalkyl-cyclene and lithium salt complexes
12/09/1998EP0882010A1 Pharmaceutical agents containing perfluoroalkyl-containing metal complexes and the use thereof in tumour therapy and interventional radiology
12/09/1998EP0719251B1 Bicyclo (2.2.2) octane derivatives cholecystokinin and/or gastrin antagonists
12/09/1998EP0700392B1 Use of macrocyclic metal complexes as temperature probes
12/08/1998US5847227 Method for producing aryl alkyl hydroperoxides
12/08/1998US5847120 Long-lived homogenous oxidation catalysts
12/08/1998US5846986 Therapeutic phenoxyalkylazoles and phenoxyalkylazines
12/08/1998US5846519 Method for imaging mammalian tissue using 1-substituted-1,4,7-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
12/03/1998DE19724186A1 Verfahren zur Mono- und 1,7-Bis-N- Hydroxyalkylierung von Cyclen und die entsprechenden N-ß-Hydroxyalkyl-1,4,7,10-tetraazacyclododecan-Li-Salz-Komplexe A process for mono- and 1,7-bis-N- hydroxyalkylation of cycles and the corresponding N-.beta.-hydroxyalkyl-1,4,7,10-tetraazacyclododecane-Li-salt complexes
12/02/1998CN1200720A Carboxylic acid derivatives, their prepn. and their use
12/01/1998US5843997 Excitatory amino acid receptor antagonists
12/01/1998US5843942 Aromatic amino ethers as pain relieving agents
11/1998
11/26/1998WO1998052929A1 Anti-inflammatory piperazinyl-benzyl-tetrazole derivatives and intermediates thereof
11/26/1998WO1998052915A2 Leukotriene b4 derivatives, in particular oximo-ltb4 antagonists
11/26/1998WO1998052914A1 Leukotriene b4 derivatives, in particular 7-methylcyclohexyl-ltb4 antagonists
11/26/1998DE19722848A1 Leukotrien-B¶4¶-Derivate, insbesondere Oximo-LTB¶4¶-Antagonisten Leukotriene B¶4¶ derivatives, in particular oximo-LTB¶4¶ antagonists
11/26/1998CA2291123A1 Leukotriene b4 derivatives, in particular oximo-ltb4 antagonists
11/26/1998CA2291112A1 Leukotriene b4 derivatives, in particular 7-methylcyclohexyl-ltb4 antagonists
11/25/1998EP0879223A1 Aromatic polycyclic retinoid-type derivatives, method for preparing same, and use thereof for making pharmaceutical and cosmetic compositions
11/25/1998CN1200117A Phenylacetic acids, processes for their preparation and agents containing them
11/24/1998US5840758 Useful in the treatment of inflammatory diseases
11/24/1998US5840294 Method for treating amyloidosis
11/19/1998WO1998051683A1 Herbicidal tetrazolinones
11/19/1998WO1998051662A2 Compounds and methods for the inhibition of the expression of vcam-1
11/19/1998WO1998051289A2 Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
11/19/1998CA2428130A1 Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
11/18/1998CN1040750C Polyazamacrocyclic compounds for complexation of metal ions
11/12/1998WO1998050394A1 Nitric oxide carriers based on polyazamacrocycle complexes
11/12/1998WO1998050342A1 Protease inhibitors
11/12/1998WO1998050031A1 Inhibitors of protein isoprenyl transferases
11/12/1998WO1998050030A1 Inhibitors of protein isoprenyl transferases
11/12/1998WO1998050029A1 Inhibitors of protein isoprenyl transferases
11/12/1998CA2289602A1 Protease inhibitors
11/12/1998CA2288330A1 Benzoyl amino acid derivatives useful as inhibitors of protein isoprenyl tranferases
11/12/1998CA2287981A1 Nitric oxide carriers based on polyazamacrocycle complexes
11/11/1998EP0876337A2 New lh-rh antagonists with improved effectiveness
11/11/1998EP0859768A4 Amine acid salt compounds and process for the production thereof
11/11/1998CN1198744A Amine acid salt compounds and process for the production thereof
11/10/1998US5834521 Treatment of progestin mediated maladies; osteoporosis, cancer
11/10/1998US5834481 Hypotensive agents
11/05/1998WO1998049151A1 A process for the preparation of 1,4,7,10-tetraazacyclododecane
11/04/1998EP0875888A1 Optical recording medium and recording and/or reproduction method using the same
11/04/1998EP0874809A1 Carbamoyloxy derivatives of mutiline and their use as antibacterials
11/04/1998EP0874645A2 Perfluoroalkyl-containing metal complexes and their use in nmr diagnostics
11/04/1998EP0827495A4 Substituted-pent-4-ynoic acids
10/1998
10/29/1998WO1998047969A1 Alkyl, alkenyl and alkynyl chrysamine g derivatives for the antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid deposition
10/29/1998WO1998047904A1 Herbicidal sulfonamides
10/29/1998WO1998047879A1 Substituted phenyl derivatives, their preparation and use
10/29/1998CA2286607A1 Alkyl, alkenyl and alkynyl chrysamine g derivatives for the antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid deposition
10/29/1998CA2285424A1 Substituted phenyl derivatives, their preparation and use
10/29/1998CA2285293A1 Herbicidal sulfonamides
10/28/1998EP0873295A1 Dimer-selective rxr modulators and methods for their use
10/27/1998US5827887 Biphenyl compounds
10/22/1998WO1998046786A1 Combinatorial libraries of peptidomimetic aminothioether acids
10/22/1998WO1998046562A1 A process for the preparation of 4-bromomethyl diphenyl compounds
10/22/1998CA2286862A1 Combinatorial libraries of peptidomimetic aminothioether acids
10/21/1998EP0872479A1 Chelated complexes of paramagnetic metals with low toxicity
10/21/1998EP0651740B1 Amino acid linked nitrogen mustard derivatives and their use as prodrugs in the treatment of tumours
10/21/1998CN1040328C Preparation method of complex salts of hematoporphyrin and of its derivatives
10/20/1998US5824696 Medicaments
10/20/1998US5824691 Guanidine derivatives as inhibitors of Na+ /H+ exchange in cells
10/15/1998WO1998045296A1 A process for the preparation of tetraazamacrocycles
10/15/1998WO1998045242A1 Retinoid activity regulators
10/13/1998US5820849 Cascade polymer complexes, process for their production and pharamceutical agents containing said complexes
10/08/1998WO1998043678A2 Tetraaza- or n2s2- complexants, and their use in radiodiagnostics or radiotherapy
10/07/1998EP0869123A2 Phenylacetylene derivatives
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