Patents
Patents for C07D 257 - Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms (9,612)
06/2002
06/04/2002US6399043 Radiolabeled macrocyclic gadolinium complexes with substantially better neural compatibility; enhanced signal intensity for nuclear spin tomography; water solubility and low osmolality; stable; nmr; radioimaging
05/2002
05/30/2002WO2002042248A2 Naphthalene derivatives
05/30/2002WO2000076489A3 Method of inhibiting amyloid protein aggregation and imaging amyloid deposits
05/30/2002US20020065278 Non-imidazole aryloxyalkylamines
05/30/2002US20020065275 To increase insulin secretion, which makes them useful for treating type II diabetes
05/30/2002US20020065230 Bis(aminomethyl)carbonyl compounds as inhibitors of cysteine protease (cathepsin K) and serine proteases; bone or cartilage loss, e.g., osteoporosis, periodontitis; antiarthritic agents; rheumatic diseases; gingivitis
05/29/2002EP1208090A1 Herbicidaltetrazolinone derivatives
05/29/2002EP1019531A4 A method to assay enzymatic covalent bond formation and cleavage
05/29/2002CN1351596A Tetrazoline-one derivative
05/29/2002CN1351592A Acyl derivatives which treat VL4-4 related disorders
05/29/2002CN1085663C Aromatic amino ethers as pain relieving agents
05/28/2002US6395749 Carboxamide compounds, methods, and compositions for inhibiting PARP activity
05/23/2002WO2002040446A1 Glucagon antagonist/inverse agonist
05/23/2002WO2002040445A1 Glucagon antagonists/inverse agonists
05/23/2002WO2002040444A1 Glucagon antagonists/inverse agonists
05/23/2002US20020061509 Detecting modulators of parathyroid hormone related peptide expression; obtain cells, transform with expression vectors, culture transformed cells, expose to modulator, monitor cell for adjustment gene expression
05/16/2002US20020058820 Adding ammonia water to a reaction solution containing a 5,5'-bi-1H- tetrazoledisodium salt; recovering pure 5,5'-bi-1H- tetrazolediammonium salt
05/16/2002US20020058807 Process for preparation of N-1 protected N ring nitrogen containing cyclic polyamines and products thereof
05/16/2002US20020058653 Administering cyclic polyamine compound to elevate white blood cell (WBC) count
05/16/2002US20020058155 Cyclic tertiary amine compound and organic electroluminescent device containing the compound
05/16/2002DE10117242C1 New dimeric tetraazacyclododecane derivatives and their metal complexes useful as components of diagnostic agents, especially X-ray contrast agents, and radiotherapeutics
05/15/2002CN1349525A Di-aryl acid derivatives as PPAR receptor ligands
05/15/2002CN1349485A 糖皮质激素受体调制剂 Glucocorticoid receptor modulators
05/15/2002CN1084743C 毒蕈碱拮抗剂 Muscarinic antagonist
05/14/2002US6388088 Antidiabetic agents
05/14/2002US6387891 Compounds with chelation affinity and selectivity for first transition series elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury
05/10/2002WO2002036118A2 Heterocyclic derivatives useful as pharmaceutical agents
05/08/2002EP1203767A1 Heterocyclic-substituted alkylamide acat inhibitors
05/08/2002EP1202961A1 Arylsulfonamido-substituted hydroxamic acid derivatives
05/08/2002EP1202732A2 Method for treating chronic pain using mek inhibitors
05/08/2002EP1202726A2 Method for treating chronic pain using mek inhibitors
05/08/2002CN1348441A N-substituted arylsulfonyl-lamino hydroxamic acids
05/08/2002CN1347693A Noval compound, its synthetizing process and therapeutic use
05/07/2002US6384279 Oxidizing a diamidodiol to form a diacid followed by coupling with an aryl diamine
05/07/2002US6384075 Treating diseases in which mast cell dysfunction is involved
05/02/2002WO2001081298A3 Cyclic carboxylic acids as integrin antagonists
05/02/2002US20020052512 Diaminopropionic acid derivatives
05/02/2002US20020052495 Pyramidine or triazine derivatives which specifically inhibit the binding of endothelin to the receptor
05/02/2002US20020052354 Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction
05/02/2002US20020052348 Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase
05/02/2002EP1201240A2 Heterocyclic derivatives useful as pharmaceutical agents
05/02/2002EP1200398A1 3-arylsulfonyl-2-(substituted methyl)propanoic acid derivates as matrix metalloproteinase inhibitors
05/02/2002EP1200395A1 Urea derivatives as inhibitors of ccr-3 receptor
04/2002
04/30/2002US6380223 For therapy of diseases, such as obesity, diabetes, inflammation
04/30/2002CA2358678A1 Heterocyclic derivatives useful as pharmaceutical agents
04/30/2002CA2053478C Magnetic resonance imaging agent
04/25/2002US20020049202 Administering halogenated amidino or oxyamidino compound to treat diseases caused by nitric oxide synthase
04/25/2002US20020049190 Useful in binding nitric oxide; inhibiting tumor growth
04/24/2002CN1346350A Compound which inhibiti leukocyte adhesion mediated by VLA-4
04/24/2002CN1083442C Process for prepn of tetraazaacrocycles
04/23/2002US6376655 Physically functional materials
04/23/2002US6376532 Neurotransmitter
04/23/2002US6376484 For prevention and/or treatment of various kinds of inflammatory disease
04/23/2002CA2032261C Antiviral polyheterocyclic dimers
04/18/2002WO2002030884A2 Sulfide and disulfide compounds and compositions for cholesterol management and related uses
04/18/2002WO2002030882A2 Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
04/18/2002WO2002030863A2 Ether compounds and compositions for cholesterol management and related uses
04/18/2002WO2002030860A2 Ketone compounds and compositions for cholesterol management and related uses
04/18/2002US20020045664 Estrogen mimetics lacking reproductive tract effects
04/18/2002DE10047794A1 New RNA-cleaving polyaza-cycloalkane complex, useful e.g. in medical genetics, preferentially cleaves after an unpaired uridine
04/18/2002DE10046934A1 Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren A process for the fermentative production of non-proteinogenic L-amino acids
04/18/2002CA2425678A1 Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
04/18/2002CA2425674A1 Sulfide and disulfide compounds and compositions for cholesterol management and related uses
04/18/2002CA2425121A1 Ether compounds and compositions for cholesterol management and related uses
04/17/2002CN1344801A Method for production of non-proteinogen L-amino acid by fermentation
04/11/2002WO2002028810A2 Retinoids for the treatment of emphysema
04/11/2002US20020042431 Zwitterionic tachykinin receptor antagonists
04/10/2002CN1344262A Perfuoroalkylamide, prodn. thereof and use thereof in diagnostics
04/10/2002CN1344160A Heterocyclic aromatic compounds useful as growth hormone secretagogues
04/10/2002CN1082508C antivirally active heterocyclic azahexane derivatives
04/09/2002US6369232 Antidiabetic agents
04/09/2002US6369073 Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase
04/04/2002WO2002026721A1 Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof
04/04/2002US20020040024 A phenoxy substituted piperidine derivative, useful for treating or preventing histamine H3 receptor activity
04/04/2002US20020040003 Tyrosine phosphatase inhibitors useful in the treatment or prevention of Type II Diabetes Mellitus
04/04/2002US20020039767 Batch processing using nucleophilic compound
04/04/2002CA2419631A1 Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof
04/03/2002EP1193250A1 Phenyl sulfamate derivatives
04/03/2002EP0874645B1 Perfluoroalkyl-containing metal complexes and their use in nmr diagnostics
04/03/2002CN1343203A Process for preparation of 1,4,7,10-tetraazacyclododecane
04/02/2002US6365583 Methods to enhance white blood cell count
03/2002
03/28/2002WO2002024630A1 Pharmaceutical compounds useful as modulators of endocannabinoid-mediated response
03/28/2002WO2002024629A1 Zwitterionic tachykinin receptor antagonists
03/28/2002WO2002024235A2 Prochelators of radiometal labeled molecules
03/28/2002WO2002009651A3 Fatty acid synthase inhibitors
03/28/2002US20020037905 N-phenyl-N'-(2-carboxyphenyl) urea, for example; chloride channel blockers; such as for treating bone metabolic disorders
03/28/2002US20020037896 Bicyclic compounds
03/28/2002DE10040858A1 Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung Perfluoroalkyl-containing complexes with polar radicals, process for their preparation and their use
03/28/2002CA2423356A1 Zwitterionic tachykinin receptor antagonists
03/27/2002EP1191106A1 Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren
03/27/2002EP1189873A1 Excitatory amino acid receptor modulators
03/27/2002EP1189609A1 Cxcr-4 receptor antagonists - thrombopoietin mimetics
03/27/2002CN1342137A N2 phenylamidine derivatives
03/26/2002US6362371 β2- adrenergic receptor agonists
03/26/2002US6362212 Oxime derivative and bactericide containing the same as active ingredient
03/26/2002US6362210 Carboxylic acid amides, pharmaceutical compositions containing these compounds and their use
03/21/2002WO2002022627A2 Ligands for metabotropic glutamate receptors
03/21/2002WO2002022584A1 Thrombin inhibitors
03/21/2002WO2002022581A1 Nitrogen-containing compounds and their use as glycine transport inhibitors
03/21/2002US20020035267 Tetrazolyl-phenyl acetamide glucokinase activators
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