Patents
Patents for C07D 223 - Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom (8,732)
01/2006
01/19/2006US20060013852 Use of organic compounds
01/19/2006CA2574002A1 Method for chiral inversion of (s)-(+)- and (r)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide and optically enriched mixtures thereof
01/19/2006CA2573372A1 Sulfonamide derivatives
01/18/2006EP1616867A1 Hydroxycarboxylic acid derivatives
01/18/2006EP1616859A1 Substituted cyclohexyl carboxylic acid compounds
01/18/2006EP1615633A2 Chemokine receptor binding heterocyclic compounds with enhanced efficacy
01/18/2006CN1721409A Dibenzo(b,f)azepine derivatives
01/12/2006WO2006002764A1 4-trifluoromethoxyphenoxybenzol-4'-sulfonic acids, method for the production and use thereof in medicaments
01/12/2006US20060009517 Tricyclic inhibitors of poly(ADP-ribose) polymerases
01/12/2006US20060009449 Naphthaline derivatives as H3 inverse agonists
01/12/2006CA2572126A1 4-trifluoromethoxyphenoxybenzol-4'-sulfonic acids, method for the production and use thereof in medicaments
01/11/2006EP1614687A1 Process for the preparation of 1,3,4,5-tetrahydro-2H-3-benzazepin-2-one derivatives and their application in the synthesis of ivabradine and its pharmaceutically acceptable salts
01/11/2006EP1613602A1 Alkylated iminodibenzyls as antioxidants
01/10/2006US6984648 TNF (tumor necrosis factor); for treating conditions such as rheumatoid and osteoarthritis, corneal, epidermal or gastric ulceration; tumor metastasis or invasion; periodontal disease and bone disease
01/10/2006US6984637 Cyclic amine derivatives-CCR-3 receptor antagonists
01/04/2006EP1383741A4 Process for the preparation of benazepril
01/04/2006CN1234692C Process for oximation reaction cyclohexaone continuous feeding
01/04/2006CN1234685C Method for separation azepine derivative out of mixture contg. amine and azepine derivative
01/03/2006US6982350 reduction of 4,5-dimethoxy-1-cyano-benzocyclobutane, resolution with optically active diacid (N-acetyl-L-glutamic acid), amidification and reduction; improved yield and optical purity; chemical intermediates; antiischemic agents
01/03/2006US6982263 Peptidyl carbamates; treatments for osteoporosis and autoimmune diseases
12/2005
12/29/2005WO2005123659A1 Method of synthesising (1s)-4,5-dimethoxy-1- (methylaminomethyl)-benzocyclobutane and the addition salts thereof, and use of same for the synthesis of ivabradine and the pharmaceutically-acceptable addition salts thereof
12/29/2005WO2005122671A2 An improved process for the preparation of oxcarbazepine and related intermediates
12/28/2005EP1608374A1 2-phenoxy- and 2-phenylsulfomamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders
12/27/2005US6979736 Process for the preparation of benazepril hydrochloride
12/22/2005WO2005097778A8 Tetrahydrobenzazepines as histamine h3 receptor ligands
12/22/2005US20050282872 Novel thyroid receptor ligands and method II
12/22/2005US20050282858 Substituted cycloalkylcarboxamides: 1-((1-(4-Chlorophenyl)cyclopropyl)carbonyl)pyrrolidin-3-ol and 1-Acetyl-4-(4-{1-[(3-phenylpyrrolidin-1-yl)carbonyl]cyclopropyl}phenyl)piperazine; 11- beta hydroxyl steroid dehydrogenase type 1 inhibitors; mineralcorticoid receptor antagonists; antidiabetic agents
12/22/2005US20050282797 Reacting oximinostilbene with chlorosulfonyl isocyanate in an inert organic solvent and isolating and hydrolyzing reaction product; use in treatment of epilepsy
12/21/2005EP1606255A2 Cyclic derivatives as modulators of chemokine receptor activity
12/20/2005US6977303 Highly enantiomerically pure lactam-substituted propanoic acid derivatives and methods of making and using same
12/20/2005US6977298 Tricyclic inhibitors of poly(ADP-ribose) polymerases
12/15/2005WO2005118550A1 A process for the preparation of iminostilbene derivatives
12/15/2005WO2005118549A2 Compounds having affinity for dopamine d3 receptor and uses thereof
12/15/2005WO2005117865A1 Naphthaline derivatives useful as histamine-3-receptor ligands
12/14/2005EP1603880A1 Quinolinone/benzoxazinone derivatives and uses thereof
12/14/2005EP1603651A2 Distillative method for separating hexamethylenediamine from a mixture comprising hexamethylenediamine, -aminocapronitrile and tetrahydroazepine
12/14/2005CN1706831A Prepn process of Lappaconite hydrobromide
12/08/2005US20050272666 Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
12/07/2005EP0957917B1 Vitronectin receptor antagonists
12/07/2005CN1704406A Intermediate for the preparation of epimino
11/2005
11/30/2005EP1600443A1 Process for the preparation of oxcarbazepine
11/30/2005CN1703404A Enantioselective process for the preparation of both enantiomers of 10,11-dihydro-10-hydroxy-5h-dibenz [b,f]azepine-5-carboxamide and new crystal forms thereof
11/30/2005CN1703401A Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
11/29/2005CA2194189C Process for producing cyclic lactames
11/24/2005WO2005111027A1 Novel method of synthesising 1,3,4,5-tetrahydro-2h-3-benzazepin-2-one derivatives and use thereof in the synthesis of ivabradine and the salts thereof for addition to a pharmaceutically acceptable acid
11/24/2005WO2005111026A1 Novel method of synthesising 1,3-dihydro-2h-3-benzazepin-2-one derivatives and use thereof in the synthesis of ivabradine and the salts thereof for addition to a pharmaceutically acceptable acid
11/24/2005WO2005110993A1 Novel method of synthesising ivabradine and the salts thereof for addition to a pharmaceutically acceptable acid
11/24/2005WO2005110992A1 Amido compounds and their use as pharmaceuticals
11/24/2005WO2005110984A1 Process for producing cyclic n-hydroxyimide compound
11/24/2005WO2005068643A3 Biochemical synthesis of 6-amino caproic acid
11/24/2005WO2004113297A9 Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
11/24/2005US20050261495 Lactam Compound
11/24/2005US20050261376 reduction of 4,5-dimethoxy-1-cyano-benzocyclobutane, resolution with optically active diacid (N-acetyl-L-glutamic acid), amidification and reduction; improved yield and optical purity; chemical intermediates; antiischemic agents
11/24/2005US20050261308 1-(2-Chloro-6-piperazin-1-yl-pyrimidin-4-ylmethyl)-3,4-dihydro-1H-quinolin-2-one; substituted benzoxazinone compounds; 5-HT6 modulators/antagonists; Parkinson's disease, Huntington's disease, manic depression, psychoses, Alzheimer's disease and memory disorders
11/24/2005US20050261279 antipsychotic agents; phenylsulfonyl compounds; 7-Methoxy-8-(3-phenoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-3-benzazepine; schizophrenia
11/24/2005US20050261274 1-[3-Methyl-1-(5-methyl-6-oxo-benzo[b]-1,4-diazepin-7-ylcarbamoyl)-butyl]-cyclohexanecarboxylic acid amide; inhibit processing of amyloid precursor protein (production of A beta -peptide); neurological disorders related to beta -amyloid production: Alzheimer's disease, Down's Syndrome
11/24/2005CA2565238A1 Amido compounds and their use as pharmaceuticals
11/23/2005EP1598333A1 Process for the preparation of (1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane, acid addition salts thereof and its use for the synthesis of ivabradine and for its pharmaceutically acceptable acid addition salts
11/23/2005EP1596868A1 Method for treating severe heart failure and medicament therefor
11/23/2005EP1280777B1 Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
11/23/2005CN1700919A Method for treating severe heart failure and medicament therefor
11/23/2005CN1699545A Apparatus and method for controlling biofilms
11/23/2005CN1699331A Process for the synthesis of (is)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane and uses thereof
11/23/2005CN1228326C Method for producing N-alkenyl amides
11/17/2005WO2005108368A1 Adamantyl-acetamide derivatives as inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
11/17/2005US20050256104 Protease inhibitors
11/17/2005CA2568241A1 Adamantyl-acetamide derivatives as inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
11/16/2005EP1330464B1 Phosphino-aminophosphines, catalyst complexes and enantioselective hydrogenation
11/16/2005EP0873406B1 Protein induced by deprenyl
11/16/2005CN1227226C Preparation of Lactams from aliphatic alpha, omega-dinitriles
11/16/2005CN1227218C Process for preparing 6-aminocaproamide
11/15/2005CA2248686C Process for depolymerizing polycaprolactam processing waste to form caprolactam
11/10/2005US20050250814 Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity
11/10/2005US20050250811 Such as 14-O-[4-hydroxy-N-valyl-piperidin-3-yl]-sulfanylacetylmutilin
11/09/2005EP1593433A1 Method for producing epsilon-Carpolactam and method for reactivating catalyst for producing epsilon-Carpolactam
11/09/2005EP1592684A1 Malonamide derivatives as gamma-secretase inhibitors
11/09/2005EP1240139B1 Method for producing n-alkenyl amides
11/09/2005EP1179341B1 Remedies or preventives for diseases in association with chemokines
11/09/2005CN1226250C Anthracene derivatives and organic electroluminescent device made by using the same
11/08/2005US6962913 Benzo-1,4-diazepin-2-ones as inhibitors of Aβ protein production
11/03/2005US20050245740 Method for producing E-caprolactam
11/03/2005US20050245534 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
11/03/2005US20050245507 7-Phenylsulfonyl-tetrahydro-3-benzazepine derivatives as antipsychotic agents
11/03/2005US20050245501 Succinoylamino lactams as inhibitors of A-beta protein production
11/03/2005DE19910403B4 3-Hydroxy-1,2,3,3a-tetrahydro-benzo[b]cyclopent[e]azepin-4,10(5H,10aH)-dion-Derivate enthaltende Arzneimittel 3-hydroxy-1,2,3,3a-tetrahydro-benzo [b] cyclopent [e] azepine-4,10 (5H, 10AH) -dione derivatives of drugs containing
11/02/2005EP1590319A1 Amide derivatives and their use as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1
11/02/2005CN1689405A Compounds, compositions, and methods for controlling biofilms
11/01/2005US6960576 Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
10/2005
10/26/2005EP1589014A1 Process for the preparation of 1,3-dihydro-2H-3-benzazepin-2-one and application to the preparation of ivabradine and their pharmaceutically acceptable salts
10/26/2005EP1589005A1 Process for the synthesis of Ivabradine and its pharmaceutically acceptable acid addition salts
10/26/2005EP1289965B1 Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
10/26/2005EP1129071B1 Phenyl-substituted cyclic enaminones
10/25/2005US6958330 useful as synthetic intermediates in the preparation of inhibitors of beta-amyloid peptide release described in U.S. patent application Ser. No. 08/996,422; 5-amino-7-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-one for example
10/25/2005US6958329 1-[3-Methyl-1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]-azepin-7-ylcarbamoyl)-butyl]-cyclohexanecarboxylic acid amide; inhibit processing of amyloid precursor protein (production of A beta -peptide); neurological disorders related to beta -amyloid production: Alzheimer's disease, Down's Syndrome
10/20/2005WO2005097778A1 Tetrahydrobenzazepines as histamine h3 receptor ligands
10/20/2005WO2005097738A1 Novel sulfonamide derivative
10/20/2005WO2005030794B1 Hemiasterlin derivatives and uses thereof
10/20/2005WO2004071460A3 Cyclic derivatives as modulators of chemokine receptor activity
10/20/2005US20050234041 Substituted 1-benzazepines and derivatives thereof
10/20/2005US20050234039 Substituted lactams as inhibitors of Abeta protein production
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