Patents for C07B 53 - Asymmetric syntheses (6,231)
02/2013
02/13/2013CN102924206A Water-phase green preparation method of 1,3-disubstituted-3-aryl allyl compound and application of 1,3-disubstituted-3-aryl allyl compound
02/06/2013CN102909070A Load type chiral catalyst and preparation method thereof
02/06/2013CN101421285B Ferrocenediphosphines
02/05/2013CA2586527C Process for transition metal-catalyzed asymmetric hydrogenation of acrylic acid derivatives, and a novel catalyst system for asymmetric transition metal catalysis
01/2013
01/31/2013WO2012150825A9 Method for preparing optically pure (s)-cyclohexylamino acid derivative
01/30/2013CN102906273A Method for producing acyloxypyranone compound, method for producing alkyne compound, and method for producing dihydrofuran compound
01/30/2013CN101844980B Method for preparing chiral alpha-hydroxy-beta-keto ester compound by utilizing chiral beta-alkoxy beta'-alkamine as catalyst
01/30/2013CN101495491B Process for production of optically active aminophosphinylbutanoic acid
01/24/2013WO2013011930A1 Method for producing optically active tetrahydroquinoline
01/23/2013CN102887808A Preparation method of multi-substituted indanol derivatives
01/23/2013CN101967166B Synthesis method of chiral cis-bromo.ammine.bis(ethylenediamine) cobalt bromide
01/23/2013CN101565393B 3-(substituted bisulfonyl fluromethane)-1-propylene compound, synthetic method and applications thereof
01/22/2013US8357820 Process for producing N-protected amino acid
01/22/2013CA2382779C Chiral ligands, transition-metal complexes thereof and uses thereof in asymmetric reactions
01/16/2013EP2546257A1 Bisphosphate compound and asymmetric reaction using same
01/16/2013CN102875601A Preparation method and application for phosphine-oxazoline ligand, and ionic metal complex, enantiomer or racemate thereof
01/16/2013CN102875278A Method for synthesizing optically-active 2-(2', 3'-allene group) malonate
01/16/2013CN101270113B Preparation of multi-chiral catalyst, and application of the catalyst in preparation of cyclic carbonates with high optical activity
01/09/2013EP2543437A2 Homogeneous asymmetric hydrogenation catalyst
01/02/2013CN102858787A Bisphosphate compound and asymmetric reaction using same
01/02/2013CN102101868B 1,1'-bicarboline N,N'-dioxocompound and synthesis and application thereof
01/02/2013CN101972672B S-acylation L-cysteine and application of salt thereof as catalyst for asymmetrical organic synthesis reaction
01/02/2013CN101384532B Process for preparing optically active alcohols
12/2012
12/27/2012WO2012176830A1 1,2-bis(dialkylphosphino)-4,5-(methylenedioxy)benzene derivative, method for manufacturing same, metal complex having this 1,2-bis(dialkylphosphino)-4,5-(methylenedioxy)benzene derivative as a ligand, and asymmetric hydrogenation method
12/27/2012WO2012176715A1 1-amino-2-vinyl cyclopropane carboxylic acid amide, salt of same, and method for producing same
12/27/2012WO2012175837A1 Processes for preparing phosphorus-containing α- and β-amino acids and derivatives thereof
12/26/2012EP2537825A1 Method for producing 1-amino-1-alkoxycarbonyl-2-vinylcyclopropane
12/19/2012EP2534161A1 Enantiomerically enriched aminodiphosphines as ligands for the preparation of catalysts for asymmetric synthesis
12/19/2012CN102834370A Method for producing 1-amino-1-alkoxycarbonyl-2-vinylcyclopropane
12/19/2012CN102826947A Method for catalytic synthesis of chiral propargylamine compound by chiral copper catalyst
12/18/2012CA2694320C Method of producing optically active n-(halopropyl)amino acid derivative
12/18/2012CA2556891C Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols
12/12/2012CN102822161A Method for producing optically active n-monoalkyl-3-hydroxy-3-arylpropylamine compound
12/12/2012CN102816181A High electron-deficient axially chiral diphosphine ligand and synthetic method thereof
12/12/2012CN102816109A Method for synthesizing Hantzsch ester
12/12/2012CN101525291B Green asymmetric synthesis method of chiral bicyclics compound
12/12/2012CN101080399B Process for producing optically active epoxy compound, complex for use in the process, and process for producing the same
12/05/2012CN102807463A Method for synthesizing chiral sulfocompound by transition metal catalysis
12/05/2012CN102093343B N-aryl axially chiral carbene-oxazoline compound and application thereof
12/05/2012CN101519401B Intermediate (S)-2-(2-thiophene ethylamine)(2-chlorphenyl)methyl acetate of clopidogrel and method for preparing salts thereof
12/04/2012CA2501373C Mixtures of chiral monophosphorus compounds used as ligand systems for asymmetric transition metal catalysis
11/2012
11/28/2012CN101233099B Process for production of mono-substituted alkylated compound using aldimine or derivative thereof
11/27/2012CA2569849C Monophosphine compounds, transition metal complexes thereof and production of optically active compounds using the complexes as asymmetric catalysts
11/22/2012WO2012158515A1 Process for the preparation of protease inhibitors
11/22/2012WO2012158513A1 Processes and intermediates
11/22/2012US20120296088 Synthesis of udp-glucose: n-acylsphingosine glucosyl transferase inhibitors
11/15/2012WO2012153684A1 Ruthenium-diamine complex and method for producing optically active compound
11/15/2012CA2832994A1 Ruthenium-diamine complex and method for producing optically active compound
11/14/2012CN102781948A Enantiomerically enriched aminodiphosphines as ligands for the preparation of catalysts for asymmetric synthesis
11/14/2012CN102775418A Synthesis and application of novel chiral quaternary ammonium salt phase-transfer catalyst
11/14/2012CN101671357B (S)-Alpha, Alpha-fluorine-containing diaryl-2-pyrrolidine methanol derivative as well as preparation and applications thereof
11/08/2012WO2012150825A2 Method for preparing optically pure (s)-cyclohexylamino acid derivative
11/07/2012CN102766071A Chiral reduction method of statin intermediates
11/07/2012CN102040594B C2 axisymmetric chiral bisoxazoline ligand compound containing imidazole salt ion pair group, and preparation and application thereof
11/01/2012WO2012147925A1 Method for producing five-membered ring-containing compound
11/01/2012WO2012147897A1 Method for producing amine compound
11/01/2012US20120277455 Novel chiral phosphorus ligands
10/2012
10/31/2012EP2518050A1 Process for production of optically active 3-substituted glutaric acid monoamide
10/31/2012CN102757364A Preparation and synthetic method of chiral nitrogenous compound
10/31/2012CN101973951B Chiral D-oxazoline and application thereof
10/31/2012CN101863805B (S)-N-(2(3-(trifluoromethyl) phenyl) methyl)-tertiary butyl-2-sulfinamide and synthesis method thereof
10/24/2012EP2513016A1 Improved method for producing intermediates for the production of macrocycles that are inhibitors of the proteasomic degradation of p27, such as argyrin and derivatives thereof
10/24/2012CN102746335A Preparation method of chiral phosphine oxide
10/17/2012EP2509933A1 Kinetic resolution
10/17/2012CN102731572A Perfluoroalkyl group-containing phosphine ligand, preparation method thereof, application thereof, and metal complex
10/17/2012CN101972673B Catalyst capable of enhancing catalytic activity of heterogeneous asymmetric catalytic reaction and preparation method thereof
10/11/2012WO2012137460A1 Novel ruthenium complex and process for producing optically active alcohol compound using same as catalyst
10/11/2012CA2830481A1 Novel ruthenium complex and method for preparing optically active alcohol compounds using the same as a catalyst
10/10/2012CN102718768A Chiral five-membered bicyclic guanidine compound, preparation method and application thereof
10/10/2012CN102285984B Preparation method of (2R, 3R, 11bR)-dihydrotetrabenazine and relevant compounds
10/10/2012CN101628927B Method for three-dimensionally selectively preparing Beta-gemcitabine hydrochloride by using 1, 3, 5-3-O-benzoyl-Alpha-D-ribofuranose as raw materials
10/03/2012CN102702015A Preparation method of (2S, 3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
10/03/2012CN102008978B Chiral catalyst and preparation method and application thereof
09/2012
09/26/2012EP2502897A1 Method for producing optically active bicyclo [3.1.0]hexane derivative using oxygen
09/26/2012CN102690291A Imidazole ionic liquid supported chiral phosphine ligands and preparation method thereof
09/26/2012CN102688779A Preparation of phosphine ligand ruthenium catalyst and application thereof in asymmetric reduction
09/19/2012CN102686558A Process for production of optically active 3-substituted glutaric acid monoamide
09/19/2012CN102675017A Method for preparing chiral diaryl- substitute methylamine
09/19/2012CN102675016A Alpha-keto ester compound with gamma chiral center and synthetic method thereof
09/18/2012CA2443702C Echinocandin process
09/13/2012WO2012121079A1 Compound and method for producing same, as well as method for producing oseltamivir phosphate
09/12/2012EP2496589A1 Novel chiral phosphorus ligands
09/12/2012CN102665908A Heterogeneous rhodium metal catalysts
09/12/2012CN102659561A Method for preparing S-benzylsuccinic acid
09/12/2012CN102659494A Method for asymmetric synthesis of 3,3-disubstituted-2-oxindole compound
09/04/2012US8258345 Hydroxylation of β-dicarbonyls with zirconium catalysts
09/04/2012US8258340 Method for producing β-mercapto carboxylic acids
08/2012
08/29/2012EP2492275A1 Novel ruthenium carbonyl complex having a tridentate ligand and manufacturing method and usage therefor
08/29/2012CN101845056B C1 symmetrical chiral diene ligand, synthesis method and application thereof to asymmetric reactions
08/22/2012CN102643246A Method for synthesizing chiral 2-carbonyl oxazoline
08/16/2012WO2012108367A1 Quaternary ammonium salt
08/15/2012CN1852887B Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same
08/15/2012CN102633677A Nonsymmetrical alkylation method for glycine tert-butyl ester derivatives
08/14/2012CA2449836C Stereoselective preparation of cyclic l-amino acids
08/09/2012WO2012104866A1 Chiral 1-(4-methylphenylmethyl)-5-oxo-{n-[(3-t-butoxycarbonyl- aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion
08/08/2012EP2484667A1 Optically active quaternary ammonium salt having axial asymmetry and process for producing alpha-amino acid and derivative thereof with the same
08/08/2012EP2482978A1 Heterogeneous rhodium metal catalysts
08/08/2012CN102627704A Beta-cyclodextrin derivative and preparation method and application thereof
08/08/2012CN102627572A Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols
08/08/2012CN102626655A Aldol reaction catalyst and preparation method and application thereof
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