Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
04/1988
04/12/1988CA1235129A1 (S)-.alpha.-ETHYL-2-OXO-1-PYRROLIDINEACETAMIDE
04/07/1988WO1988002374A2 Renin inhibitory peptides having novel c-terminal moieties
04/07/1988WO1988002362A1 Aryl-n-aminoalkyl-4-(sulfonamido)benzamides, antiarrhytmic agents and compositions thereof
04/07/1988WO1988002258A1 Use of an adenosine, hypoxanthine and ribose-containing solution for improved protection of the heart during surgery
04/07/1988WO1988001997A3 Azaindole and indolizine derivatives, processes for their production and their use as pharmaceuticals
04/07/1988WO1988000587A3 5-HETERO- OR ARYL-SUBSTITUTED-IMIDAZO[2,1-a]ISOQUINOLINES
04/06/1988EP0262852A2 Prodrugs of antihypercholoesterolemic compounds
04/06/1988EP0262552A1 Pharmaceutical preparation for the treatment of hypertension
04/06/1988EP0262448A1 Imidazolylguanidine derivatives, process for their preparation and medicines containing them
04/06/1988EP0262395A2 Sulfonamido-ethyl compounds, medicines containing them and process for their preparation
04/06/1988EP0262373A1 Benzothiazepine derivates
04/06/1988EP0262318A2 Renin-inhibiting amino acid derivatives
04/06/1988EP0262125A1 AICA riboside for the prophylactic treatment of diseases with restricted blood flow.
04/05/1988US4736064 Anticholesterol, antilipemic agents
04/05/1988US4736057 Cyclohexane derivatives
04/05/1988US4736043 Process for the preparation of indole derivatives
04/05/1988US4736042 Chemical intermediates
04/05/1988US4736034 Cardiotonic agents
04/05/1988US4735965 Crystalline amine salt; water solubility; materials handling
04/05/1988US4735963 Anti-platelet aggregating 1,3-oxathiane derivatives, compositions, and method of use therefor
04/05/1988US4735952 Anti-hypertensive
04/05/1988US4735936 Pharmaceutical composition containing inositol triphosphate
04/05/1988US4735933 Hypotensive
04/05/1988CA1234804A1 Adenosine receptor antagonists
03/1988
03/30/1988EP0261814A2 Therapeutic composition containing gamma-linolenicacid and an assimilable form of calcium
03/30/1988EP0261804A1 Dopamine-beta-hydroxylase inhibitors
03/30/1988EP0261759A2 Amido substituted naphthalene and intermediates thereof
03/30/1988EP0261633A2 6-(Imidazolylphenyl)-4-imino-pyrimidinones hypotensive agents
03/30/1988EP0261539A2 Substituted phenyl-sulphon amides
03/30/1988EP0261185A1 7-oxoprostacycline derivatives and process for their manufacture.
03/29/1988US4734417 Lipid- and cholesterol-reducing derivatives of halo-biphenyl primary alcohols
03/29/1988US4734410 Lactam derivatives and their use as hypotensive agents
03/29/1988US4734405 Combination product
03/29/1988US4734283 Method of making a food composition containing inosotoltriphosphate and the composition
03/29/1988CA1234572A1 Process for preparing pyridinecarboxylic esters of dopamine and of its n-alkyl derivatives
03/24/1988WO1988001997A2 Azaindole and indolizine derivatives, processes for their production and their use as pharmaceuticals
03/24/1988WO1987005909A3 Renin inhibitors having a lactam pseudo dipeptide
03/24/1988WO1987004430A3 Fused benzazepines
03/23/1988EP0260852A2 Nucleoside Analogues
03/23/1988EP0260675A1 4-[N-(substituted)-aminophenyl]-substituted 1,4-di-(hydro)-pyridine derivatives, process for their preparation and medicaments containing them
03/23/1988EP0260613A2 Imidazopyridine derivatives, their preparation and their use as PAF-antagonists
03/23/1988EP0260605A2 Dihydropyridine-5-phosphonic acid cyclic ester
03/22/1988US4733000 Oligopeptides for hypotensives
03/22/1988US4732985 2-oxygen containing heteroalkoxyalkyl dihydropyridine intermediates
03/22/1988US4732896 Aromatic derivatives comprising an aminoalkoxy chain, the salts thereof, the process for preparing these derivatives and salts and the application thereof in therapeutics
03/22/1988US4732890 Retro-inverso hexapeptide neurotensin analogs, process for their preparation and pharmaceutical compositions containing them
03/16/1988EP0260127A2 Xanthine derivatives, their preparation and pharmaceutical compositions containing them
03/16/1988EP0260118A1 Selective amidination of diamines
03/16/1988EP0259871A1 Indolinones substituted by heterocycles, process for their preparation and medicines containing them
03/16/1988EP0259838A2 Pharmaceutical composition containing A 1,4-dihydropyridine derivative and an acylated 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
03/16/1988EP0259835A2 Pyridazinone derivatives
03/16/1988EP0259793A1 Naphthyl derivatives, medicaments containing them and processes for their preparation
03/16/1988EP0259782A1 Naphthalene and indane derivatives, medicaments containing these compounds and processes for their preparation
03/16/1988EP0259707A2 Hydroxybutenolide derivatives, production and use thereof
03/16/1988EP0259468A1 Cyclodextrinclathrates of carbacycline derivatives and their use as medicinal drugs.
03/15/1988US4731478 Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them
03/15/1988US4731383 Antiarrhythmia agents
03/15/1988US4731376 2-(-(2,2,5,5-tetramethyl-3-pyrrolin-3-carbonyl))-amino derivatives
03/15/1988CA1234113A1 Aminoalkyl-imidazothiadiazole-alkenecarboxylic acid amides, new intermediates for their preparation, their preparation and their use in medicaments
03/15/1988CA1234111A1 2-(pyridinyl or hydroxyphenyl)pyrido-(2,3-d) pyrimidin-5-ones, their preparation and their cadiotonic use
03/15/1988CA1234103A1 Pharmaceutical preparations containing ( )-cyanidan -3-ol derivatives, the use thereof, novel substituted ( )-cyanidan-3-ol derivatives, and processes for producing them
03/10/1988WO1988001508A1 Benzodiazinone-pyridone compounds, cardiotonic compositions including the same, and their uses
03/09/1988EP0259206A1 Derivatives of 1,4-dihydropyridine, process for their preparation and pharmaceutical compositions containing them
03/09/1988EP0259092A1 Substituted hexahydroarylquinolizines
03/09/1988EP0259086A2 Prodrugs of antihypercholesterolemic compounds
03/09/1988CN87105724A 4-nitrogen substituted isoquinolinol compounds having cardiotonic, phosphodiesterase fraction iii inhibiting properties and / or renal vasodilating properties
03/08/1988US4730061 Plant growth regulators
03/08/1988US4730053 S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives
03/08/1988US4730042 Compounds 1 or 3-hydroxy-4-benzyl-6-methyl-7-(4-isopropylamino-butoxy)-1,3-dihydro[3,4-C]pyridine and 2-methyl-3-(4-isopropyl-aminobutoxy)-4-(1'-morphilinomethyl)-5-hydroxymethyl-6-benzyl pyridine, useful for treating cardiac arrhythmias
03/08/1988US4730003 Tricyclic compounds for treating heart and circulatory diseases
03/08/1988US4729985 Hypotensive agents
03/08/1988CA1233775A1 Monoclonal antibody with a high affinity for digoxin
03/02/1988EP0258175A2 5-hetero- or aryl-substituted-imidazo[2,1-a]isoquinolines
03/02/1988EP0258096A2 Indane derivatives, process for their preparation, their use as medicines, pharmaceutical compositions containing them and the intermediates obtained
03/02/1988EP0258095A1 Decahydroquinoline derivatives, method for their preparation and intermediates thereof, their use as medicaments and their pharmaceutical compositions
03/02/1988EP0258009A2 2,6-Bis(chloromethyloxycarbonyloxymethyl)pyridine
03/02/1988EP0257992A2 Prophylactic and therapeutic agents for cerebral ischemia
03/02/1988EP0257921A2 New 1,3-diaryl cyclopentanes and derivatives thereof as paf antagonists
03/02/1988EP0257918A1 Quinolone cardiac stimulants
03/02/1988EP0257864A1 Antiarrhythmic agents
03/02/1988EP0257787A1 Process for producing optically active benzene-sulfonamide derivates
03/02/1988EP0257768A1 2-Isopropyl-2-phenyl-5-(N-methyl-2-phenylethylamino)-valeronitrile derivatives and processes for their preparation
03/02/1988EP0257762A2 Novel glycerol derivative and anti-hypertensive agent
03/02/1988EP0257616A2 Dihydropyridine derivates and pharmaceutical composition thereof
03/02/1988EP0257610A2 Process and intermediates for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives and for the synthesis of bicyclo(4.2.0)octane derivatives
03/02/1988EP0257485A2 Mixture of positively inotropically acting dihydropyridines and ACE inhibitors, and their use in medicaments
03/02/1988EP0257312A2 A new cartilage-derived leukocyte elastase-inhibitor
03/02/1988EP0257306A1 Diselenobis benzoic acid amides of primary heterocyclic amines, process for producing the same and pharmaceutical compounds comprising the same
03/02/1988EP0176546B1 Isothiuronium salts
03/02/1988EP0096720B1 Process for the preparation of B-[(2-methylpropoxy)-methyl]-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine
03/01/1988US4728741 1-substituted-2-mercapto benzimidazole compounds and intermediates
03/01/1988US4728725 Bradykinin potentiating pentapeptide; hypotensives, diagnostics
03/01/1988US4728663 N-[(1H-imidazol-1-yl)alkyl]benz[cd]-indol-2-amines and use in inhibiting thromboxane synthetase enzyme
03/01/1988US4728661 Cardiotonic phenyl oxazolones
03/01/1988US4728654 Quinolone inotropic agents
03/01/1988US4728651 Systemic or ocular
03/01/1988US4728649 3-oxo-piperazin-1-yl-ergolines exhibiting antidopaminergic activity
03/01/1988US4728647 Amides derived from quinoline, and anxiolytic compositions containing them
03/01/1988CA1233465A1 Aminopropanol derivatives of substituted 2-hydroxy- propiophenones, their preparation, and therapeutic agents containing these compounds
02/1988
02/25/1988WO1988001166A1 Stimulation of angiogenesis and promotion of endothelialisation