Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
01/1989
01/17/1989CA1248947A1 Pyrrol-1-ylphenyldihydropyridazinones, their preparation and their use
01/12/1989WO1989000192A1 Production of kallikrein
01/12/1989WO1989000161A1 Malic acid derivative containing renin inhibiting peptides
01/11/1989EP0298919A2 4-amino-substituted 1,2-dihydroxynaphthalene derivatives
01/11/1989EP0298820A1 Peptide derivatives and their therapeutic application
01/11/1989EP0298466A2 Substituted alkene carboxylic acid amides and derivatives
01/11/1989EP0298452A2 2H-1-benzopyrane derivatives substituted in position 4 by aryl or N-heteroaryl
01/10/1989US4797410 Calcium channel blocking compounds
01/10/1989US4797404 Pharmaceutical preparation comprising co-dergocrine and a calcium antagonist
01/10/1989US4797401 Cardiovascular disorders
01/10/1989US4797390 Inositol triphosphate pharmaceutical compositions
01/10/1989US4797278 Hypocholesterolemically and/or hypotriglyceridemically active products and their use
01/10/1989CA1248536A1 Benzoil acid derivatives
01/10/1989CA1248533A1 Phenylacetonitrile derivatives
01/10/1989CA1248526A1 [3.2.0]bicycloheptanone oxime ethers with valuable therapeutic properties
01/10/1989CA1248525A1 Carbacyclins, process for their manufacture and their use as medicaments
01/10/1989CA1248523A1 OCCLUSION COMPOUND OF 2-NITROXYMETHYL-6- CHLOROPYRIDINE WITH .beta.-CYCLODEXTRIN AND PROCESS FOR PREPARATION THEREOF
01/10/1989CA1248521A1 10,11-dihydro-5h-dibenzo [a,d] cycloheptadiene derivatives, their preparation and their use
01/04/1989EP0297913A2 Production of Kallikrein
01/04/1989EP0297855A1 Aminocyclopentyl ethers and their preparation and pharmaceutical formulation
01/04/1989EP0297816A2 Homocyclostatine and cyclostatine containing polypeptides as antihypertensive agents
01/04/1989EP0297815A2 Fluorine containing renin inhibitors
01/04/1989EP0297770A1 Novel HMG-COA reductase inhibitors
01/04/1989EP0297651A1 Anellated indole derivatives
01/04/1989EP0297593A2 Treating agent for heart failure
01/04/1989EP0297435A2 Aminopropanol derivatives of 3-(3'-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds
01/04/1989EP0297380A2 Indolyl propanols, process for their preparation, their uses and preparation containing them
01/04/1989CN1030075A Substituted pyrroles
01/04/1989CN1030074A Leukotriene antagonists
01/03/1989US4795814 Process for preparing novel dihydropyridine derivatives
01/03/1989US4795750 Hypotensive agents
01/03/1989US4795646 Fluidized bed process
01/03/1989CA1248115A1 Process for preparing 7-(2-aminoethyl)-1,3-benzthia- or oxa-zol-2(3h)-ones
01/03/1989CA1248111A1 Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
01/03/1989CA1248110A1 Piperazine derivatives, processes for production thereof, and pharmaceutical compositions comprising said compounds as active ingredient
01/03/1989CA1248103A1 Substituted 5-phenyl-2- (1h)-pyridimidinone compounds
01/03/1989CA1248102A1 Phenylpiperazine derivatives and process for producing the same
01/03/1989CA1248099A1 Indoline and 2-indolinone derivatives
01/03/1989CA1248098A1 Process for preparing fenoldopam 4',8-bis-hydrogen sulfates
01/03/1989CA1248096A1 Optionally n-substituted aminodesoxy-1,4;3.6- dianhydrohexitol derivatives, processes for their preparation and their use
12/1988
12/29/1988WO1988010299A1 A process for preparing a protein or polypeptide, a dna sequence coding for the polypeptide, a microorganism containing the dna sequence as well as the polypeptide and its use as a pharmaceutical preparation
12/29/1988WO1988010269A1 Growth factors
12/28/1988EP0297068A2 Mammal intestine hormone precursor
12/28/1988EP0296892A2 Novel linear derivatives of arginine vasopressin antagonists
12/28/1988EP0296830A2 Ergoline derivatives
12/28/1988EP0296748A1 Cycloalkylamides of (8Beta)-1-alkyl-6-(substituted) ergolines
12/28/1988EP0296732A1 Leukotriene antagonists
12/28/1988EP0296581A2 Amino acid 1,2-diketo derivatives as renin inhibitors
12/28/1988EP0296553A2 Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
12/28/1988EP0296316A1 1,4-Dihydropyridine enantiomers
12/28/1988EP0296265A1 Aminopropanol derivatives of 3-(3-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds
12/28/1988EP0296264A1 Aminopropanol derivatives of 3-(2-hydroxyphenyl)-1-propanone, process for their preparation and medicines containing these compounds
12/28/1988EP0296225A1 Carbamoyloxylabdanes
12/28/1988EP0213180A4 Neovascularization inhibitors and methods for their production and use.
12/28/1988CN88103539A 3.4-dihydro-2-alkyl-3-oxo-n-aryl-2h-(1) benzothieno (3,2-e)-1,2-thiazine-4-carboxamide-1,1-dioxides
12/28/1988CN88103112A Amides
12/28/1988CN88102356A 1,3-dioxanes
12/27/1988US4794121 Antispasmodic, bronchodilator, anticonvulsant, analgesic, hypotensive, or bradycardial agent; adrenergic stimulant
12/27/1988US4794118 1,4-benzodioxane derivatives
12/27/1988US4794115 Method of treating hyperlipemia
12/27/1988US4794110 5-Aryl-11-substituted-5H,11H-pyrrolo[2,1-c][1,4]benzoxazepined as analgesic and hypotensive agents
12/27/1988US4794104 Injection
12/27/1988US4794103 Pharmaceutical compositions containing peptides of the cholecystokinin-cerulein group for the therapy of shock conditions and of respiratory and cardiocirculatory insufficiencies
12/27/1988US4794014 Counteracting deliterious effects of heavy metals, radiation and smoking
12/27/1988US4793998 Stabilized drug compositions
12/21/1988EP0295851A1 4,7-diacyloxybenzofuran derivatives
12/21/1988EP0295826A1 Method of using superoxide dismutase during surgical procedures
12/21/1988EP0295769A2 1,4 Dihydropyridine derivatives, process for their preparation and their uses in pharmaceutical compositions
12/21/1988EP0295679A2 Physiologically-active novel peptides
12/21/1988EP0295637A2 Lipid regulating compositions
12/21/1988EP0295476A2 Inclusion complexes of dipyridamole with cyclodextrins
12/21/1988EP0295331A2 Use of vitamin E for the preparation of medicaments for use in normalizing the blood coagulation in the therapy with omega-3-type highly unsaturated fatty acids
12/21/1988EP0295294A1 Peptidylaminodiols
12/21/1988CN88103236A Cardiotonic tricyclic oxazolones
12/21/1988CN88103091A Phosphorus-containing hmg-c0a reductase inhibitors, new intermediates and method
12/20/1988US4792559 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators
12/20/1988US4792553 Diene derivatives and vasodilators containing the same
12/20/1988CA1247116A1 7,8,9,10-tetrahydro-6-oxo-6h-dibenzo/b,d/pyranyloxy- propanes
12/20/1988CA1247103A1 Basic oxime ethers and a process for preparing same
12/20/1988CA1247098A1 Antihypertensive 1-piperazine-3-(4-fluorophenyl)- indane derivatives
12/20/1988CA1247093A1 N-¬(amino)alkyl|-1-pyrrolidine, 1-piperidine and 1-homopiperidine-carboxamides (and thiocarboxamides) with sulfur linked substitution in the 2, 3 or 4- position
12/20/1988CA1247092A1 Pyridyl n-oxides
12/20/1988CA1247086A1 Renally active tetrapeptides
12/20/1988CA1247085A1 Process for preparing n-carboxyalkylproline- containing tripeptides
12/15/1988WO1988009793A1 3,4-DIHYDRO-2-ALKYL-3-OXO-N-ARYL-2H-[1]BENZOTHIENO[3,2-e]-1,2-THIAZINE-4-CARBOXAMIDE-1,1-DIOXIDES
12/15/1988WO1988009792A1 Ester-substituted thienotriazolodiazepine compounds and their medicinal use
12/15/1988WO1988009789A2 3-indolepyruvic acid derivatives and pharmaceutical use thereof
12/15/1988WO1988009605A2 Traumatic and ischemic brain injury treatment with opiate-receptor antagonists
12/15/1988WO1988009603A2 Central nervous system injury treatment with opiate-receptor antagonists
12/14/1988EP0295161A1 3-Acylaminomethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives, their preparation and therapeutical use
12/14/1988EP0295049A2 Thiophene sulfonamide antiglaucoma agents
12/14/1988EP0295010A1 Derivatives of alkylaminoalkyl ureas and cyanoguanidines
12/14/1988EP0294994A1 3-4-Dihydro-2-alkyl-3-oxo-N-aryl-2H-[1]benzothieno[3,2-el]-1,2-thiazine-4-carboxamide-1,1-dioxides
12/14/1988EP0294973A1 Dopamine-beta-hydroxylase inhibitors
12/14/1988EP0294695A2 New polyoxygenated labdane derivatives, a process for their preparation, and their use as medicaments
12/14/1988EP0294647A2 Thiadiazinones
12/14/1988CN88103014A Process for preparation of novel and derivatives
12/14/1988CN88102858A Process for preparing hydrazine derivatives use as antihypertension agent
12/14/1988CN88102650A Diarylalkyl-substituted alkylamines, process for preparing them, their use, and medicaments containing them
12/13/1988US4791203 Cardiotonic agents