Patents for A61P 9 - Drugs for disorders of the cardiovascular system (159,484)
06/1988
06/01/1988EP0269295A1 Therapeutic agents
06/01/1988EP0269220A2 Derivatives of alpha-hANP and their production
06/01/1988EP0269105A2 Derivatives of cyclohexane, preparations containing them and their use
06/01/1988EP0268975A2 Process for the preparation of mono, bi and tricyclic amino acids, intermediary compounds and their preparation
06/01/1988EP0268813A1 Process for the preparation of a compressible granulate from celiprolol hydrochloride, free of binders
06/01/1988EP0268585A1 Tertiary hydroxyalkylxanthines, their manufacturing process, medicines containing them and use thereof.
06/01/1988CN87107975A Preparation of therapeutic agents
05/1988
05/31/1988US4748239 Benzazepine derivatives
05/31/1988US4748182 Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
05/31/1988US4748175 Pyrimido[5,4-B][1,4]oxazine derivatives and pharmaceutical compositions containing them
05/31/1988US4748155 Pharmacologically active tripeptides and process for their synthesis
05/25/1988EP0268389A2 Cyclopenthyl ethers and their preparation and pharmaceutical formulation
05/25/1988EP0268178A1 Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation
05/25/1988EP0268148A1 Tetrahydronaphthalene derivatives and medicaments containing them
05/25/1988EP0268146A1 Enhancement of prazosin
05/25/1988EP0267986A1 "(2-amino-4-aryl-thiazole-5-yl)ethanols and their derivatives having diuretic activity and methods for preparing the same
05/25/1988CN87107875A Tetrahydronaphthalene derivatives
05/25/1988CN85108458B Process for preparation of novel 9-chloro-1,5-benzothiazepine derivatives
05/24/1988US4746729 Cartilage-derived leukocyte elastase-inhibitor
05/24/1988US4746676 Carboxyalkyl dipeptide compounds
05/24/1988US4746671 Pharmaceutical use of [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters
05/24/1988US4746664 Substituted-3,4-dihydro-4-(2,4,6-trimethoxyphenylimino)-2(1H)-pyrimidones useful as cardiotonic, antihypertensive, cerebrovascular vasodilator and anti-platelet agent
05/24/1988US4746660 Process for reducing reflex tachycardia in the treatment of hypertension employing a combination of a diazacyclopentene derivative and a pyridazinone derivative
05/24/1988US4746658 2-phenyl-imidazo-pyrazines, -pyridazines and -triazines
05/24/1988US4746656 1,2,4,7-tetrahydro-2-oxopyrazolo[1,5-a]pyrimidine derivatives
05/24/1988CA1237129A1 Aminoguanidine derivatives and a process for the preparation thereof
05/24/1988CA1237079A1 Antiarrhythmic class iii process
05/19/1988WO1988003537A1 Novel peptides
05/19/1988WO1988003531A1 Cardiotonic imidazolylphenylpyrrol-2-ones
05/19/1988WO1988003529A1 2-methylmercapto-3-cyano-4-(o-difluoromethoxyphenyl)-6-phenyl-1,4-dihydropyridine
05/18/1988EP0267878A1 N9-cyclopentyl-substituted adenine derivatives
05/18/1988EP0267723A2 New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
05/18/1988EP0267703A1 Human apolipoprotein AI and variant form of the same expressed in Escherichia coli
05/18/1988EP0267676A2 Use of 1,3-di-n-butyl-7-(2-oxypropyl) xanthine in the treatment of cerebrovascular or cerebral senility associated disorders, peripheral vascular disease and proliferative skin diseases
05/18/1988EP0267439A2 Alpha-(phenylalkyl) pyridinealkanol derivatives
05/17/1988US4745198 1,3-dioxan-5-ylalkenoic acids
05/17/1988US4745196 Orally active phosphonyl hydroxyacyl prolines
05/17/1988CA1236834A1 Substituted 1-pyridyloxy-3-indolylalkylamino-2- propanols, preparation, and use thereof
05/11/1988EP0267155A2 Bicyclic compounds
05/11/1988EP0266968A2 Gelled ointment of vasodilating agent
05/11/1988EP0266956A2 Azulene derivatives and pharmaceutical compositions containing them
05/11/1988EP0266950A2 Nor-statine and nor-cyclostatine polypeptides
05/11/1988EP0266922A1 Dihydropyridine derivatives, their preparation and their use
05/11/1988EP0266640A2 A pharmaceutical compound containing nifedipine
05/11/1988EP0266558A2 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them
05/11/1988EP0266504A2 Use of N6-[(1,2-dihydro-1-acenaphthylenyl) methyl]-adenosine in the preparation of pharmaceutical compounds for treating congestive heart failure
05/11/1988CN87101499A A preparation method of the polypeptide with nor-statine and nor-cyclostatine
05/10/1988US4743686 Process for the isomerization of asocainol
05/10/1988US4743613 Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity
05/10/1988US4743612 Prodrug derivatives of the cardiotonic agent 4-ethyl-1,3-dihydro-5-(4-(2-methyl-1H-imidazol-1-yl)benzoyl)-2H-imidazol-2-one, composition containing them, and method of using them to treat cardiac failure
05/10/1988US4743608 Pyridone-pyridyl-imidazolyl and triazolyl compounds and their use as cardiotonic agents
05/10/1988US4743607 Enhancing myocardial contractile force
05/10/1988US4743599 1,5-benzothiazepine derivatives and compositions containing them
05/10/1988CA1236460A1 Chromone- and thiochromone-substituted 1,4- dihydropyridine derivatives, several processes for their preparation and their use in medicaments
05/10/1988CA1236458A1 Active compounds
05/05/1988WO1988003166A1 Human apolipoprotein ai and variant form of the same expressed in escherichia coli
05/05/1988WO1988003143A1 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(5'-trimethylsilyl-2'-furyl)-1,4-dihydropyridine
05/05/1988WO1988003022A1 Relatively low molecular weight polypeptides as renin inhibitors
05/04/1988EP0266336A1 1-[3-(2-Dialkylaminoethoxy)-2-thienyl]-3-phenyl-1-propanones and their acid addition salts, process for their preparation and pharmaceutical compositions containing them
05/04/1988EP0266170A2 Peptide derivative and its production
05/04/1988EP0266006A2 Novel hypotensive diuretic peptides
05/04/1988EP0265947A2 Dihydropyridine derivatives, process for their preparation, pharmaceutical composition and use
05/04/1988EP0265685A2 Combination of ACE inhibitors with calcium antagonists, and their use in medicines
05/04/1988EP0265662A2 Pharmaceutic composition
05/04/1988EP0265640A2 Azaindole and indolizine derivatives, processes for their production and their use as pharmaceuticals
05/04/1988CN87107150A Dihydropyridine derivatives, their preparation and their use
05/04/1988CN87104319A 苯并吡喃衍生物 Benzopyran derivatives
05/03/1988US4742172 Antiarrhythimia
05/03/1988US4742154 GLN- or ASN-vasopressin compounds
05/03/1988US4742069 Calcium antagonist, antiangina, antiischemic, hypotensive
05/03/1988CA1236116A1 Process for the production of s(-)-3-/3-acetyl-4- (3-tert.butylamino-2-hydroxy-propoxy)-phenyl/-1,1- diethylurea and its salts
05/03/1988CA1236110A1 Aminoalkyleneamido chroman derivatives having anti-hypertensive activity
04/1988
04/27/1988EP0264888A1 Stabilized drug compositions
04/27/1988EP0264887A1 Drug compositions stabilized against oxidation and discoloration
04/27/1988EP0264795A2 Amino acid derivatives
04/27/1988EP0264729A2 Prodrug derivatives of the cardiotonic agent 4-ethyl-1,3-dihydro-5-[4-(2-methyl-1H-imidazol-1-yl)-benzoyl]]-2H-imidazol-one
04/27/1988EP0264639A1 Aryloxyaminoalkanes, their preparation and use
04/27/1988EP0098794B1 Carbacyclines, process for their preparation and their use as medicines
04/26/1988US4740602 Indole derivatives
04/26/1988US4740523 Interfuranylene prostacyclins
04/26/1988US4740513 Cardiac stimulants
04/26/1988US4740509 12- and 13-bromoergolines useful for treating hypertension
04/26/1988US4740508 Ureidoalkanoylaminocarbonyl amino and imino acids and esters
04/21/1988WO1988002756A2 Peptide derivatives
04/21/1988WO1988002746A1 Medicaments containing alpha-halogenated dicarboxylic acids
04/20/1988EP0264114A1 Alpha-[(phenylmethoxy)methyl]pyridine-alkanol derivatives
04/19/1988US4739067 4-(1,2,5,6-tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines and 4-(hexahydro-1-alkyl-3-pyridinyl)-2-thiazolamines
04/19/1988US4739060 Radioactive and non-radioactive iodobutyrophenone derivative
04/19/1988US4739050 Calcium antagonist, anticoagulant
04/19/1988US4738979 Adrenergic receptors; anti-convulsive drug; treatment of metabolic and neutral disorders
04/19/1988US4738965 2-oxo-4-(2'-difluoromethylthiophenyl)-5-methoxycarbonyl-6-methyl-1,2,3,4-tetrahydropyrimidine
04/19/1988US4738954 Hypotensive agents, analgesics, nervous system disorders
04/19/1988CA1235417A1 2-(n-pyrrolidino)-3-isobutoxy-n-substituted phenyl-n- benzyl-propylamines, their preparation and pharmaceutical use
04/13/1988EP0263521A2 Gonadoliberine analogues with improved solubility, process for their preparation, agents containing them and their use
04/13/1988EP0263480A1 Tetrahydroquinoline derivatives, method for their preparation, their use and pharmaceutical compositions containing them
04/13/1988EP0263229A1 Phenol derivatives, their preparation and the use thereof
04/13/1988EP0263174A1 Increased vascular perfusion following administration of lipids
04/12/1988US4737511 Cardiotonic imidazolylphenylpyrrol-2-ones
04/12/1988US4737506 Anti-arteriosclerotic pyridyl or imidazolyl derivatives of carbonyloxyalkyl hantzsch esters
04/12/1988US4737487 VIP type peptides