Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
08/1998
08/05/1998EP0855914A1 Stable formulations of mhc-peptide complexes
08/05/1998EP0649407B1 Dimeric piperidine, tetrahydropyridine and piperazine derivatives
08/05/1998EP0575430B1 Preparation of a medicament for the treatment of addiction to drugs and substances of abuse
08/05/1998EP0553263B1 1'-aminospiro-[isoquinoline-4(1h),3'-pyrrolidine]- 1,2',3,5'(2h)-tetrones and analogs thereof useful as aldose reductase inhibitors in vivo
08/05/1998CN1189834A Condesned thiazole derivatives, having 5-HT receptor affinity
08/05/1998CN1189829A Piperazino derivatives as neurokinin antagonists
08/05/1998CN1189823A Cyclic amidino agents useful as nitric oxide synthase inhibitors
08/05/1998CN1189821A Substituted oximes, hydrazones and olefins as neurokinin antagonists
08/05/1998CN1189376A Pure Chinese medicine for stopping drugs and its prepn. tech.
08/05/1998CN1039416C Process for preparing novel pyrido (3,2-B) (1.5) benzothiazepines
08/05/1998CA2221687A1 Tumor necrosis related receptor, tr5
08/04/1998US5789565 Serine threonine kinase receptor, ALK-7
08/04/1998US5789543 Vertebrate embryonic pattern-inducing proteins and uses related thereto
08/04/1998US5789447 Nitric oxide releasing compounds as protective agents in ischemia reperfusion injury
08/04/1998US5789425 Imidazolidinone derivatives, their acid adducts and therapeutic drugs for senile dementia
08/04/1998US5789412 Piperazides derived from arylpiperazine, processes for their preparation, their use as medicaments and pharmaceutical compositions comprising them
08/04/1998US5789406 Indeno 1,2-E!pyrazine-4-ones, their preparation and the medicaments containing them
08/04/1998US5789404 Central nervous system disorders and antiserotonin agents
08/04/1998US5788987 Time-specific controlled release dosage formulation
08/04/1998CA2161533C Indole derivatives
08/04/1998CA2149242C Quinuclidine derivative for treatment of inflammatory and gastrointestinal disorders
08/04/1998CA2132706C Acylaminoindole derivatives as 5-ht1 agonists
08/04/1998CA2119647C Heteroaryl amines as novel acetylcholinesterase inhibitors
08/04/1998CA2071093C Ethanolamine benzoate derivatives; process for preparing the same and pharmaceutical compositions containing them
08/04/1998CA2066248C Esters of thienyl carboxylic acids and amino alcohols, their quaternization products, and manufacture and use of said compounds
08/03/1998CA2220852A1 Tumor necrosis related receptor, tr4
07/1998
07/30/1998WO1998032863A2 Mammalian thioredoxin
07/30/1998WO1998032766A1 SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS
07/30/1998WO1998032759A1 Method of making (1s, 4r)-1-azabicyclo[2.2.1]heptan-3-one and (1r, 4s), 1-azabicyclo[2.2.1]heptan-3-one
07/30/1998WO1998032758A1 Single pot process for producing (z)-azabicyclo oxime ethers
07/30/1998WO1998032754A1 Imino-aza-anthracyclinone derivatives for the treatment of amyloidosis
07/30/1998WO1998032753A1 THIAZOLE BENZENESULFONAMIDES AS β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY
07/30/1998WO1998032733A1 Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
07/30/1998WO1998032724A1 Novel tetralone or benzopyranone derivatives and process for producing the same
07/30/1998WO1998032448A1 Facilitation of repair of neural injury with cm101/gbs toxin
07/30/1998WO1998032441A1 Use of central cannabinoid receptor antagonists for regulating appetence
07/30/1998WO1998032438A1 Il-8 receptor antagonists
07/30/1998WO1998032425A1 Pharmaceutical formulations with delayed drug release
07/30/1998WO1998027108A3 New amide compounds and their use as nitric oxide synthase inhibitors
07/30/1998WO1998024780A3 Substituted pyrimidinone and pyridinone compounds and their use
07/30/1998WO1998014168A3 Dosage form providing a sustained and ascending drug release
07/30/1998WO1998010787A3 Pharmaceutical compositions for the treatment of immune disorders
07/30/1998CA2279241A1 Mammalian thioredoxin
07/30/1998CA2278779A1 Substituted amino bicyclic-.beta.-lactam penam and cepham derivatives as cysteine protease inhibitors
07/30/1998CA2278739A1 Thiazole benzenesulfonamides as .beta.3 agonists for the treatment of diabetes and obesity
07/30/1998CA2278661A1 Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour reguler l'appetance
07/30/1998CA2278427A1 Il-8 receptor antagonists
07/30/1998CA2270884A1 Single pot process for producing (z)-azabicyclo oxime ethers
07/30/1998CA2269683A1 Method of making (1s, 4r)-1-azabicyclo¬2.2.1|heptan-3-one and (1r, 4s), 1-azabicyclo¬2.2.1|heptan-3-one
07/29/1998EP0855444A2 Aspartic proteinase 2 (ASP2)
07/29/1998EP0855443A2 cDNA clone HE8CH90 that encodes a 7-transmembrane receptor
07/29/1998EP0855442A2 Central nervous system transcription regulator polypeptide and a DNA sequence to which a protein containing the polypeptide binds
07/29/1998EP0855396A1 Thioctic acid metabolites and methods of use thereof
07/29/1998EP0855391A1 Novel isoquinoline derivatives
07/29/1998EP0855182A1 3-Deoxyglucosone production inhibitor
07/29/1998EP0854884A1 Ligand inhibitors of insulin-like growth factor binding proteins and methods of use therefor
07/29/1998EP0854881A1 IDENTIFICATION OF sel-12 AND USES THEREOF
07/29/1998EP0854868A1 Substituted hydroisoquinoline derivatives and their use as pharmaceuticals
07/29/1998EP0854726A2 Stable extract of hypericum perforatum l., process for preparing the same and pharmaceutical compositions
07/29/1998EP0854720A1 Nk-1 receptor antagonists for prevention of neurogenic inflammation in gene therapy
07/29/1998EP0854714A1 Substituted indolylpropyl-piperazine derivatives as 5-ht 1dalpha? agonists
07/29/1998EP0854711A1 gamma-RAR ANTAGONIST LIGAND OR alpha-RAR AGONIST LIGAND AS AN APOPTOSIS INHIBITOR
07/29/1998EP0854709A1 Use of boswellic acid and its derivatives for inhibiting normal and increased leucocytic elastase or plasmin activity
07/29/1998EP0794949B1 Novel 3,5-dioxo-(2h,4h)-1,2,4-triazine derivatives, their preparation and use as drugs
07/29/1998EP0722434B1 Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
07/29/1998EP0693068B1 Phenylpyrrole derivatives and their use as antipsychotic agents
07/29/1998EP0686155B1 Xanthine derivatives as adenosine a1 receptor antagonists
07/29/1998EP0681571B1 Spiro-substituted azacycles as tachykinin receptor antagonists
07/29/1998EP0643688B1 Substituted (arylalkoxybenzyl)aminopropanamide derivatives, their preparation and use as anti-epileptic, neuroprotective and antidepressant agents
07/29/1998EP0626951B1 Benzisoxazole derivatives and pharmaceutical compositions containing them
07/29/1998CN1189154A 4-aryl-1-phenylalkyl-1,2,3,6-Tetrahydropyridines having neurotrophic and neuroprotective activity
07/29/1998CN1189151A 维生素d类似物 Vitamin d analogues
07/29/1998CN1039322C Preparation method of indole derivatives
07/29/1998CN1039284C Composition for treating pain and reinforcing pain relief action
07/28/1998US5786447 Opioid peptide analogs
07/28/1998US5786390 Enzyme inhibitors of enzyme monoamine oxidase
07/28/1998US5786380 Modified valproic acid
07/28/1998US5786378 Fkbp type immunophillins for nervous system disorders
07/28/1998US5786372 Heteroaryl compounds used as pharmaceuticals
07/28/1998US5786364 Nervous system disorders; psychological disorders; drug abruse
07/28/1998US5786347 Vitamin D amine and amide derivatives
07/28/1998US5786180 Antibody specific for peptide derived from amyloid precursor protein
07/28/1998US5786158 Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
07/28/1998US5786157 DNA encoding human 5-HT1D receptors and uses thereof
07/28/1998CA2221686A1 Asp2
07/28/1998CA2220851A1 Cdna clone he8ch90 that encodes a novel 7-transmembrane receptor
07/28/1998CA2141563C Novel 2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
07/28/1998CA2082527C Use of purine derivatives for anesthesia, analgesia and in vivo organ preservation
07/23/1998WO1998031802A2 Secreted proteins and polynucleotides encoding them
07/23/1998WO1998031702A1 16-hydroxy-11-(substituted phenyl)-estra-4,9-diene derivatives
07/23/1998WO1998031686A1 Substituted 4-(6-fluoro-(1h)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of cns-disorders
07/23/1998WO1998031663A1 Novel modifications to 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonyl-aminobenzene and processes for preparing said compound
07/23/1998WO1998031660A1 Process for preparing indane-like compounds
07/23/1998WO1998031395A1 Adenoviral-vector-mediated gene transfer into medullary motor neurons
07/23/1998WO1998031381A1 Compositions to enhance the cytoprotective effects of polycyclic phenolic compounds through the synergistic interaction with anti-oxidants
07/23/1998WO1998031365A1 Paroxetine compositions
07/23/1998WO1998031362A1 Use of pramipexole in the treatment of restless legs syndrome
07/23/1998WO1998031358A1 d-METHADONE, A NONOPIOID ANALGESIC
07/23/1998WO1998022493A3 N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
07/23/1998DE19701694A1 Neue Modifikationen des 2-Amino-4-(4-fluorbenzylamino)-l-ethoxycarbonyl-aminobenzen sowie Verfahren zu ihrer Herstellung Recent modifications of 2-amino-4- (4-fluorobenzylamino) -l-ethoxycarbonyl-diaminobenzene as well as processes for their preparation