Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
08/1998
08/19/1998CN1190967A Heterocyclylcarboxamide derivatives and their use as therapeutic agents
08/19/1998CN1190965A Diphenylmethylene piperidine derivatives
08/19/1998CN1190890A Cyclo-oxygenase inhibitor and amidine derivative salts, preparation method thereof, use thereof as drugs, and pharmaceutical compositions containing said salts
08/19/1998CA2223020A1 Human protein kinase hoacf72
08/18/1998US5795915 Use of (x-aminomethyl-3,4-dichlorobenzyl) thioacetamide derivatives for inhibiting dopamine reutake and new compounds for this use
08/18/1998US5795908 Fkbp immunophilins for enzyme inhibitors
08/18/1998US5795905 CRF receptor antagonists and methods relating thereto
08/18/1998US5795903 Anticonvulsants, antianxiety, schizophrenia, sleep disorders, brain disorders and alzheimer's or parkinson's disease
08/18/1998US5795888 Analgesics, antiinflammatory agents, antidiabetic agents
08/18/1998US5795887 Method of inducing cholecystokinin agonist activity using 1,4- Benzodiazepine compounds
08/18/1998US5795886 Anticonvulsants
08/18/1998US5795861 Methods for regulating gastrointestinal motility
08/18/1998US5795574 Use of an extract from a non-photosynthetic filamentous bacterium and composition containing it
08/18/1998CA2224123A1 Nucleic acid construct for the cell cycle regulated expression of structural genes
08/18/1998CA2215920A1 Drug binding protein
08/18/1998CA2161768C 3-(indol-3-yl) propenoic acid derivatives and as nmda antagonists
08/18/1998CA2036876C Derivatives having a naphthalenic structure; process for preparing the same and pharmaceutical compositions containing them
08/13/1998WO1998035048A2 Engineered protein kinases which can utilize modified nucleotide triphosphate substrates
08/13/1998WO1998035042A2 Activity dependent neurotrophic factor iii (adnf iii)
08/13/1998WO1998034949A2 Monocyclic compounds with four bifunctional residues having nk-2 antagonist action
08/13/1998WO1998034933A1 (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents
08/13/1998WO1998034929A1 Il-8 receptor antagonists
08/13/1998WO1998034923A1 Phenylbenzimidazole derivatives as ligands for gaba receptors
08/13/1998WO1998034919A1 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines
08/13/1998WO1998034907A1 Compounds consisting in particular of effectors of the central nervous system receptors sensitive to excitatory amino acids, preparation and biological applications
08/13/1998WO1998034643A1 Pharmaceutically active agents that impede the formation of amyloid by impeding the genesis or growth of dms
08/13/1998WO1998034637A1 Use of a polypeptide for obtaining a composition for detecting, preventing or treating a degenerative and/or autoimmune disease
08/13/1998WO1998034615A1 Pharmaceutical composition for treatment of synaptic dysfunction comprising an oxime
08/13/1998WO1998034612A1 Pharmaceutical compositions containing ibuprofen and domperidone for the treatment of migraine
08/13/1998WO1998030693A3 Tumor necrosis factor receptor 5
08/13/1998WO1998022501A3 Secreted proteins and polynucleotides encoding them
08/13/1998WO1998019512A3 Method for the preparation of citalopram
08/13/1998WO1998018466A3 Anti-neurogenic inflammatory compounds and compositions and methods of use thereof
08/13/1998DE3790166C2 Pure stereoisomers of N-cyclopropyl-methyl-nor-morphine cpds.
08/13/1998CA2280228A1 Monocyclic compounds with four bifunctional residues having nk-2 antagonist action
08/13/1998CA2280048A1 Il-8 receptor antagonists
08/13/1998CA2279929A1 Phenylbenzimidazole derivatives as ligands for gaba receptors
08/13/1998CA2279834A1 Pharmaceutically active agents that impede the formation of amyloid by impeding the genesis or growth of dms
08/13/1998CA2279531A1 Pharmaceutical composition for treatment of synaptic dysfunction comprising an oxime
08/13/1998CA2279231A1 Activity dependent neurotrophic factor iii (adnf iii)
08/12/1998EP0857781A2 Human endoglingene promoter and use thereof
08/12/1998EP0857732A1 Human pec-60-like protein and dna encoding the same
08/12/1998EP0857725A1 (N-(pyridinylmethyl)-heterocyclic)-ylideneamine compounds as nicotinic acetylcholine receptor binding agents
08/12/1998EP0857066A1 Use of nitroflavonoids for the treatment of anxiety
08/12/1998EP0857065A2 Use of 4-amino-4-(4-fluorobenzylamino)-1-ethoxy-carbonylaminobenzene for prophylaxis and treatment of sequelae of acute and chronic reduced circulation in the brain and neurodegenerative disorders
08/12/1998EP0751947B1 Glucosidic derivatives of n-acyl alkylamines exerting neuroprotective, neurotrophic and anti-inflammatory action, useful in acute and chronic disorders of the central nervous system connected with excitotoxicity
08/12/1998EP0701450B1 Recombinant viruses and their use in gene therapy
08/12/1998EP0625903B1 Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
08/12/1998EP0596891B1 Aminoalkyl-substituted 2-amino-5-mercaptothiadiazoles, their preparation and their use
08/12/1998EP0566709B1 Composition comprising a tramadol compound and acetaminophen, and its use
08/12/1998CN1190404A Neuroactive steroids of androstane and pregnane series
08/12/1998CN1190401A C-4' modified adenosine kinase inhibitor
08/12/1998CN1190393A Diaryldiamine derivatives and their use as delta opioid (ANT)-agonists
08/12/1998CN1190388A Semicarbazones having CNS activity and pharmaceutical preparations containing same
08/12/1998CN1039491C Tetrahydro-carbazole compound and its preparation and application
08/11/1998US5792874 Process for the manufacture of 8-chloro-6-(2-flourophenyl)-1-methyl-4H-imidazo 1,5A! 1,4!benzodiazepine (midazolam)
08/11/1998US5792858 Lysosphingolipid derivatives
08/11/1998US5792849 Polypeptides useful for the stimulation of glial cell (particularly, schwann cell) mitogenesis and treating glial cell tumors
08/11/1998US5792784 A pseudo-dipeptide product which is histamine or methyl-substituted histamine coupled with a amino acid; used in therapeutical, cosmetological applications and treats vision defect
08/11/1998US5792783 Capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation
08/11/1998US5792772 Enatiomerically pure hydroxylated xanthine compounds
08/11/1998US5792770 Administering as sedative, tranquilizer, anxiolytic agent
08/11/1998US5792768 Reduced side effects
08/11/1998US5792767 Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists
08/11/1998US5792766 Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
08/11/1998US5792764 Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives, their preparation and use
08/11/1998US5792763 Serotonin 5-HT1F agonists
08/11/1998US5792757 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
08/11/1998CA2113425C Androgens for stimulating the central nervous system and for treating osteoporosis
08/11/1998CA2090234C Method for providing improved analgesic effect
08/11/1998CA2076589C Naphthylethylureas and naphthylethylthioureas, the process for their preparation and pharmaceutical compositions holding same
08/06/1998WO1998033922A1 The neurotrophic factor nnt-1
08/06/1998WO1998033921A1 Novel human cystatin-like protein
08/06/1998WO1998033916A2 Secreted proteins and polynucleotides encoding them
08/06/1998WO1998033904A2 An antisense oligonucleotide preparation method
08/06/1998WO1998033815A1 Amyloid beta protein (globular assembly and uses thereof)
08/06/1998WO1998033795A1 Nanomolar, non-peptide inhibitors of cathepsin d
08/06/1998WO1998033784A1 1-phenyl-4-benzylpiperazines: dopamine receptor subtype specific ligands (d4)
08/06/1998WO1998033780A1 Endothelin antagonists: n-[[2'-[ [(4,5-dimethyl-3-isoxazolyl) amino]sulfonyl]-4-(2-oxazolyl) [1,1'-biphenyl]-2-yl]methyl] -n,3,3-trimethylbutanamide and n-(4,5-dimethyl-3-isoxazolyl) -2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl) methyl] -4'-(2-oxazolyl)[1,1'-biphenyl]-2-sulfonamide and salts thereof
08/06/1998WO1998033502A1 Use of 1-[4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1yl]-2-(6,7-dimethoxynapht-2-yl) ethane for preparing medicines for the treatment of cerebral and neuronal disorders
08/06/1998WO1998033498A1 Drugs for memory enhancement
08/06/1998WO1998033493A1 Alcoholic treatment and homeopathic pharmaceutical product
08/06/1998WO1998033492A1 Compounds and methods for therapeutic intervention in preventing diabetic complications
08/06/1998WO1998027113A3 Melanocortin derivatives for specific binding of melanocortin receptor 3, 4 or 5
08/06/1998WO1998021332A3 Secreted proteins and polynucleotides encoding them
08/06/1998WO1998019511A3 Method for the preparation of citalopram
08/06/1998WO1998016507A3 New heterocyclylmethyl-substituted pyrazol derivates and their use for treating cardiovascular diseases
08/06/1998WO1998015275A3 Method and potentiated composition for treating migraine
08/06/1998WO1998002148A3 Pharmaceutical composition
08/06/1998CA2280096A1 Nanomolar, non-peptide inhibitors of cathepsin d
08/06/1998CA2279947A1 Drugs for memory enhancement
08/06/1998CA2279326A1 Use of 1-[4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1yl]-2-(6,7-dimethoxynapht-2-yl)ethane for preparing medicines for the treatment of cerebral and neuronal disorders
08/06/1998CA2279265A1 Novel human cystatin-like protein
08/06/1998CA2279178A1 Endothelin antagonists: n-[[2'-[ [(4,5-dimethyl-3-isoxazolyl) amino]sulfonyl]-4-(2-oxazolyl) [1,1'-biphenyl]-2-yl]methyl] -n,3,3-trimethylbutanamide and n-(4,5-dimethyl-3-isoxazolyl) -2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl) methyl] -4'-(2-oxazolyl)[1,1'-biphenyl]-2-sulfonamide and salts thereof
08/06/1998CA2278595A1 Secreted proteins and polynucleotides encoding them
08/06/1998CA2222981A1 Promoter of the human endoglin gene and its use
08/05/1998EP0856579A1 An antisense oligonucleotide preparation method
08/05/1998EP0856514A1 8-substituted-1,3,8-triazaspiro[4.5]decan-4-on derivatives
08/05/1998EP0856050A1 Transforming growth factor alpha hi
08/05/1998EP0856001A1 Pyrimidine derivatives as 5ht 2c?-receptor antagonists