Patents for A61P 25 - Drugs for disorders of the nervous system (183,225)
10/1998
10/29/1998DE19716984A1 Verfahren zur Herstellung von reinem Flupirtin-Maleat und dessen Modifikation A A process for the preparation of pure flupirtine maleate and its modification A
10/29/1998CA2288227A1 A purified 20 kda presenilin 2 c-terminal fragment and methods of screening for compounds that inhibit proteolysis of presenilin 2
10/29/1998CA2288172A1 A bicyclic aryl or a bicyclic heterocyclic ring containing compounds having a combined 5ht1a, 5ht1b and 5ht1d receptor antagonistic activity
10/29/1998CA2287566A1 9,10-diazatricyclo¬4.2.1.12,5|decane and 9,10-diazatricyclo¬3.3.1.12,6|decane derivatives having analgesic activity
10/29/1998CA2287501A1 Ibuprofen thioesters as inhibitors of nf-kb-dependent pain and inflammation mediator formation
10/29/1998CA2287255A1 Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof
10/29/1998CA2287162A1 Neuroprotective compounds and uses thereof
10/29/1998CA2286106A1 5-aryl-3-(8-azabicyclo(3.2.1)oct-3-yl)-1,3,4-oxadiazol-2(3h)-one derivatives as 5-ht4 receptor ligands
10/29/1998CA2286081A1 Gastric-retained pharmaceutical composition
10/29/1998CA2272292A1 Crf antagonistic thiophenopyridines
10/28/1998EP0874050A2 Integrin ligand ITGL-TSP
10/28/1998EP0873993A1 Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
10/28/1998EP0873755A1 Prevention and treatment of enterohemorrhagic E. coli infection
10/28/1998EP0873753A1 Use of NK-1 receptor antagonists for the manufacture of a medicament in the treatment of symptoms of irritable bowel syndrome
10/28/1998EP0873406A2 Protein induced by deprenyl
10/28/1998EP0873340A1 Heterocyclic substituted cyclopentane compounds
10/28/1998EP0873338A1 Quinoline derivatives as type iv phosphodiesterase inhibitors
10/28/1998EP0873336A1 Antagonists of gonadotropin releasing hormone
10/28/1998EP0873330A1 Diarylalkenylamine derivatives
10/28/1998EP0873329A1 Novel n-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands
10/28/1998EP0873322A1 Novel compounds with analgesic effect
10/28/1998EP0873321A1 Novel amido quinoxaline diones, their production and use
10/28/1998EP0873320A1 Piperazine derivatives as tachykinin antagonists
10/28/1998EP0873317A1 Pyrimidin derivatives
10/28/1998EP0873312A1 Alpha-substituted arylsulphonamido hydroxamic acids as tnf-alpha and matrix metalloproteinase inhibitors
10/28/1998EP0873309A1 3-spiro-indolin-2-one derivatives as vasopressin and/or oxytocin receptor ligands
10/28/1998EP0873308A1 O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same
10/28/1998EP0873304A1 Metalloproteinase inhibitors
10/28/1998EP0873295A1 Dimer-selective rxr modulators and methods for their use
10/28/1998EP0873118A1 Transdermal administration of ropinirole and analogs thereof
10/28/1998EP0715620B1 1-arylcycloalkyl sulphides, sulphoxides and sulphones for the treatment of depression, anxiety and parkinson's disease
10/28/1998EP0649418B1 7-(2-aminoethyl)-benzothiazolones
10/28/1998EP0593513B1 Tryptamine analogues, their synthesis and their use as 5-ht1-like receptors or 5-ht2 receptor agonistes
10/28/1998EP0476016B1 CNS active 8-heterocyclyl-2-aminotetralin derivatives
10/28/1998CN1197461A Truncated glial cell line-derived neurotrophic factor
10/28/1998CN1197388A Pharmaceutical compsn. for oral delivery
10/28/1998CN1197077A Nucleic acid construct for cell cycle regulated expression of structural genes
10/28/1998CN1197072A New N-aryl piperidine compounds, process for their preparation and pharmaceutical compositions containing them
10/28/1998CN1197067A New naphthylpiperazine derivatives
10/28/1998CN1197059A Substituted amino compounds and their use as substances having analgesic effect
10/28/1998CN1196955A Thebaica giving-up vaccinum for man
10/28/1998CN1196932A Oral application of (+)-0-demethyltramadol as pain-killing drug
10/27/1998US5827874 Rheumatic, nonrheumatic and postoperative posttraumatic pain
10/27/1998US5827873 Alzheimer's disease
10/27/1998US5827871 Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof
10/27/1998US5827869 Substituted biphenyl isoxazole sulfonamides
10/27/1998US5827856 Method of treating insulin resistance
10/27/1998US5827847 Treatment of cognitive disorders with piperazine derivatives
10/27/1998US5827823 Method of producing analgesia using neurotrophins
10/27/1998US5827819 Pharmaceutical composition comprising a psychotropic, neurotropic or neurological drug, a polar lipid carrier, two linker functional groups and a spacer; facilitates entry of drugs into cells and tissues
10/27/1998US5827689 Encoding fatty acid biosynthesis (fabd) polypeptides expressed in bacterial genes; vaccines, immunology
10/27/1998US5827529 External preparation for application to the skin containing lidocaine
10/27/1998CA2154870C Silylated acetylcholinesterase inhibitors
10/27/1998CA2102179C Quinuclidine derivatives
10/24/1998CA2228743A1 Novel integrin ligand itgl-tsp
10/23/1998CA2235457A1 Prevention and treatment of enterohemorrhagic e. coli infection
10/23/1998CA2235438A1 Nk-1 receptor antagonists for the treatment of symptoms of irritable bowel syndrome
10/22/1998WO1998046746A1 Extracellular/epidermal growth factor like protein
10/22/1998WO1998046743A1 Novel ldl-receptor
10/22/1998WO1998046643A1 TUMOR NECROSIS FACTOR RECEPTOR RELATED PROTEINS TANGO-63d AND TANGO-63e
10/22/1998WO1998046638A1 A novel th2-specific gene
10/22/1998WO1998046636A2 β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME
10/22/1998WO1998046619A1 Glycine transporter
10/22/1998WO1998046618A1 Morphine derivatives
10/22/1998WO1998046611A1 Compounds
10/22/1998WO1998046610A1 Process for preparing single enantiomer narwedine
10/22/1998WO1998046609A1 Furopyridine, thienopyridine, pyrrolopyridine and related pyrimidine, pyridazine and triazine compounds useful in controlling chemical synaptic transmission
10/22/1998WO1998046605A1 5,7-disubstituted 4-aminopyrido[2,3-d]pyrimidine compounds and their use as adenosine kinase inhibitors
10/22/1998WO1998046604A1 5,6,7-trisubstituted-4-aminopyridol[2,3-d]pyrimidine compounds
10/22/1998WO1998046603A1 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds
10/22/1998WO1998046589A2 Indazole amide compounds as serotoninergic agents
10/22/1998WO1998046574A1 Pyridazine and phthalazine derivatives, process of their preparation and their use as anticonvulsants
10/22/1998WO1998046570A1 Substituted heteroaromatic 5-ht1f agonists
10/22/1998WO1998046563A1 Metalloproteinase inhibitors
10/22/1998WO1998046235A1 Analgesic combination
10/22/1998WO1998046227A1 Composition for treating pain
10/22/1998WO1998046226A1 Method for treating schizophrenia
10/22/1998WO1998046076A1 Retinoid related molecules for the inhibition of endothelin-1 overproduction in disease
10/22/1998WO1998034949A3 Monocyclic compounds with four bifunctional residues having nk-2 antagonist action
10/22/1998WO1998029407A3 N-(pyridinylamino)isoindolines for treating alzheimer's and depression
10/22/1998WO1998002190A3 Cationic amphiphile/dna complexes
10/22/1998DE19716713A1 Arzneimittel, enthaltend Ibuprofenthioester als Hemmer der Nf-kappaB abhängigen Bildung von Mediatoren von Entzündung und Schmerz A drug containing Ibuprofenthioester dependent as inhibitors of Nf-kappaB formation of mediators of inflammation and pain
10/22/1998DE19715594A1 Analgetika-Kombination Analgesic combination
10/22/1998CA2288171A1 Pyridazine and phthalazine derivatives, process of their preparation and their use as anticonvulsants
10/22/1998CA2287518A1 A novel th2-specific gene
10/22/1998CA2287465A1 6,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds
10/22/1998CA2287085A1 Tumor necrosis factor receptor related proteins tango-63d and tango-63e
10/22/1998CA2286909A1 5,7-disubstituted 4-aminopyrido¬2,3-d|pyrimidine compounds and their use as adenosine kinase inhibitors
10/22/1998CA2286789A1 Compounds
10/22/1998CA2286592A1 5,6,7-trisubstituted-4-aminopyridol[2,3-d]pyrimidine compounds
10/22/1998CA2286484A1 .beta.-amyloid peptide-binding proteins and polynucleotides encoding the same
10/22/1998CA2286351A1 Extracellular/epidermal growth factor like protein
10/22/1998CA2285603A1 Substituted heteroaromatic 5-ht1f agonists
10/22/1998CA2234399A1 Cdna clone hmtmf81 that encodes a novel human 7-transmembrane receptor
10/22/1998CA2231740A1 Cdna clone hmtmf81 that encodes a novel human 7-transmembrane receptor
10/21/1998EP0872550A2 cDNA clone HACCH94 that encodes a human 7-transmembrane receptor
10/21/1998EP0872247A1 Pharmaceutical formulation
10/21/1998EP0872235A1 Therapeutic agents
10/21/1998EP0871720A2 Beta-secretase, antibodies to beta-secretase, and assays for detecting beta-secretase inhibition
10/21/1998EP0871667A1 G-protein coupled receptor