A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Patents for A61K 48 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy (86,964)
12/2004
12/09/2004	US20040248145 Using vector transformation to generate transgenic cells which overexpress an enzyme which specifically digests RNA/DNA hybrids; gene expression inhibition via nuclease digestion and antisense oligonucleotide exposure
12/09/2004	US20040248141 Transgenic cell comprising nucleotide sequences which form triplex structures for use in diagnosis, prevention and treatment of skin, pigmentation and cell proliferative disorders
12/09/2004	US20040248137 Human and mammalian stem cell-derived neuron survival polypeptides
12/09/2004	US20040248114 Novel maxizyme
12/09/2004	US20040248083 Viral plasmid comprising heterologous or synthetic dimerisation sequences which promotes dimer formation of plasmid transcripts and prevents recombination between plasmid transcripts and another retrovirus present in genome; gene transfer tool; bioreactor
12/09/2004	US20040247680 Targeted delivery of controlled release polymer systems
12/09/2004	US20040247662 Systemic immune activation method using nucleic acid-lipid complexes
12/09/2004	US20040247615 A nucleic acid comprising a nucleotide sequence encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region; adenovector or DNA plasmid vaccine; cultured cells expressing the nucleic acid; vaccination
12/09/2004	US20040247613 A nucleic acid expression vector encodes the catalytic subunit of human telomerase reverse transcriptase (hTRT); immunostimulants; anticarcinogenic agents; gene therapy
12/09/2004	US20040247598 In particular of delayed-type hypersensitivity; especially administering an IL-18 binding protein or a derivative, an expression vector or a genetically engineered cell, optionally with an antiinflammatory agent such as a COX-inhibitor.
12/09/2004	US20040247596 TRANCE regulation of chondrocyte differentiation
12/09/2004	US20040247592 Administering a substance that modulates an ephrin or an Eph receptor, especially treating cancer by modulating an adhesive, migratory or chemotactic property of a cancer cell; also treating autoimmune diseases, allergies, graft versus host disease, and transplant rejection
12/09/2004	US20040247585 Recombinant alpha-galactosidase a therapy for fabry disease
12/09/2004	US20040247578 Administering into or near a site of a tumor or infectious lesion an antigen presenting cell, especially a dendritic cell, and an immunostimulatory cytokine or a nucleic acid encoding an immunostimulatory cytokine
12/09/2004	US20040247575 Especially cells containing an exogenous nucleic acid encoding VEGF, fibroblast growth factor-4, a natiuretic peptide, prostacyclin synthase, nitric oxide synthase, angiostatin, endostatin, erythropoietin, granulocyte/macrophage colony stimulating factor, an integrin, or an interleukin
12/09/2004	US20040247574 Improving stem cell homing to bone marrow by contacting them for a period insufficient for cell division to occur with a CD26 peptidase inhibitor before administering them to a patent in need
12/09/2004	US20040247567 Transfecting cells of the free flap ex vivo by perfusing with a suspension of a vector that is a nucleic acid encoding the product of interest under the control of a promoter; and reattaching the free flap to the native circulation using microvascular surgical techniques.
12/09/2004	US20040247564 Treating a tissue disorder involving a loss and/or apoptosis of cells by administering an agent that induces phosphorylation and/or activation of protein kinase B to cause proliferation; particularly administering a human stromal-derived factor-1 and a G-CSF to cause proliferation of cardiomyocytes
12/09/2004	CA2527907A1 Double-stranded hairpin rnas for rnai
12/09/2004	CA2527722A1 Biodegradable poly(beta-amino esters) and uses thereof
12/09/2004	CA2527303A1 Intravenous delivery of polynucleotides to cells in mammalian limb
12/09/2004	CA2527109A1 Oligo double-stranded rna inhibiting the expression of bcl-2 and medicinal composition containing the same
12/08/2004	EP1484409A2 Expression vector comprising short-lived drug resistance gene
12/08/2004	EP1484397A1 Peptide from antigen MUC-1 for triggering an immune response to tumor cells
12/08/2004	EP1484081A1 Systems and methods for treating ischemia
12/08/2004	EP1484067A2 Cancer control
12/08/2004	EP1484066A1 Remedy for infections
12/08/2004	EP1484063A2 Method for inhibiting rejection of transplanted tissue
12/08/2004	EP1483588A2 Screening method for identifying protective substances for treating neurodegenerative and/or ischemic disorders
12/08/2004	EP1483396A2 Wit 3.0, novel gene to control soft tissue wound healing
12/08/2004	EP1483389A2 Genetic products differentially expressed in tumors and use thereof
12/08/2004	EP1483385A2 Compositions and methods for generating an immune response
12/08/2004	EP1483384A2 Method for overexpression of zwitterionic polysaccharides
12/08/2004	EP1483375A1 A method for producing recombinant viruses using site-specific recombination
12/08/2004	EP1483289A2 Angiogenesis regulator genes, pharmaceutical preparations containing same and uses thereof
12/08/2004	EP1483281A1 Methods for producing interfering rna molecules in mammalian cells and therapeutic uses for such molecules
12/08/2004	EP1482988A1 METHOD OF RADIO−LABELLING BIOMOLECULES
12/08/2004	EP1482974A2 Electroporation methods for introducing bioactive agents into cells
12/08/2004	EP1482972A2 Treatment of immunological disorders using anti-cd30 antibodies
12/08/2004	EP1482970A1 Cancer therapy
12/08/2004	EP1482916A2 Schwann cell and phosphodiesterase inhibitors based therapy
12/08/2004	EP1143797A4 Methods for reducing adverse side effects associated with cellular transplantation
12/08/2004	EP0984925B1 Compounds, preparation and use for transferring nucleic acids into cells
12/08/2004	CN1553963A Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells
12/08/2004	CN1553958A Photochemical internalization for delivery of molecules into the cytosol
12/08/2004	CN1553952A Materials and methods to promote repair of nerve tissue
12/08/2004	CN1553806A Use of SAPR-1 for the treatment and/or prevention of scleroderma
12/08/2004	CN1552880A Use and constructing plan of anticancer recombined gland virus with tumour CHK1 as target of medicine
12/08/2004	CN1552879A Use and obtain of inactivating lumour CHK1 gene anticancer recombined gland virus constituent
12/08/2004	CN1552878A Use and obtain of selective inactivating tumour PLK1 anticancer recombined gland virus constituent
12/08/2004	CN1552877A Use and constructing method for anticancer recombined gland virus with tumour cell PLK1 as target of medicine
12/08/2004	CN1552876A Targetted liver cancer AFP gene siRNAs expression carrier and its constructing method and use
12/08/2004	CN1552855A Vascular endothelial growth factor 2
12/08/2004	CN1552734A Recombination glant associated virus carrier induced TNF concerned cytonecrosis ligand peptide segment and its use
12/08/2004	CN1552447A Adjuvant for improving hepatitis B vaccine immune effect and preparing method thereof
12/08/2004	CN1552446A Nucleic acid vaccin for preventing and treating hepatitis B virus inflammation and its preparation
12/08/2004	CN1179048C Modified MSP-1 nucleic acid sequences and method for increasing mRN-A level and protein expression in cell system
12/08/2004	CN1179047C Method for introducing substances into cells and use of said method
12/08/2004	CN1178950C Corpuscles of stannius protein and stanniocalcin
12/08/2004	CN1178671C Egg anti-inflammatory composition and isolation method and use
12/07/2004	US6828453 Phospholipid-analogous compounds
12/07/2004	US6828433 DNA encoding mutated collagen X
12/07/2004	US6828431 Compositions and methods for the therapy and diagnosis of breast cancer
12/07/2004	US6828429 Prostate-specific gene, PCGEM1, and the methods of using PCGEM1 to detect, treat, and prevent prostate cancer
12/07/2004	US6828428 IGA nephropathy-related genes
12/07/2004	US6828426 VEGF-like factor
12/07/2004	US6828424 Nucleotide sequences coding enzymatic polypeptide for use in the treatment of arthritis and cancer; for use as antiscarring agent
12/07/2004	US6828150 Antigen presenting system and methods for activation of T-cells
12/07/2004	US6828144 Method of observing vasculogenesis in vitro using cultured allantois
12/07/2004	US6828138 Recombinant sendai virus vector including a gene encoding a chemokine
12/07/2004	US6828105 Methods of their use in inhibition of growth of viruses of the picornavirus, calicivirus, togavirus and flavivirus families, as in treatment of a viral infection. The antisense antiviral compounds are substantially uncharged oligomers having a
12/07/2004	US6827938 Compositions and methods for improving kidney function
12/07/2004	US6827935 Method of and compositions for immunization with the pseudomonas V antigen
12/07/2004	CA2158834C Antisense oligos which interfere with mrna cap activity and inhibit translation
12/02/2004	WO2004104204A1 RECOMBINANT GENE MEDICINE OF ADENOVIRUS VECTOR AND GENE p53 FOR TREATING PROLIFERATIVE DISEASES
12/02/2004	WO2004104200A1 Method of controlling cell proliferation by using novel function of myeloid leukemia factor mlf1 and utilization of the same
12/02/2004	WO2004104199A2 Modulation of gene expression using dna-dna hybrids
12/02/2004	WO2004104161A2 Methods and systems for identifying naturally occurring antisense transcripts and methods, kits and arrays utilizing same
12/02/2004	WO2004104032A2 Methods and compositions related to high-titer pseudotyped retroviruses
12/02/2004	WO2004103410A1 Methods compositions and articles of manufacture for modulating bone growth
12/02/2004	WO2004103301A2 Synergistic treatment of cancer using immunomers in conjunction with chemotherapeutic agents
12/02/2004	WO2004103271A2 Disease prevention and vaccination prior to thymic reactivations
12/02/2004	WO2004103269A2 Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of the genus borrelia
12/02/2004	WO2004067563A8 Peptide inhibitors of toxins derived from ll-37
12/02/2004	WO2004065440A3 Cationic graft-copolymer for non-viral gene delivery vector
12/02/2004	WO2004050027A3 Materials and methods for treating ocular-related disorders
12/02/2004	WO2004047758A3 Methods of therapy and diagnosis using targeting of cells that express p2y10
12/02/2004	WO2004013308A3 Maxs as modifiers of the axin pathway and methods of use
12/02/2004	WO2004009788A3 Fluorescent proteins, nucleic acids encoding them and methods for making and using them
12/02/2004	WO2003085377A3 Novel pancortin-pablo protein interactions and methods of use thereof
12/02/2004	WO2003083079A8 Bone generation by gene therapy
12/02/2004	WO2003064665A3 Viral vector
12/02/2004	WO2003028632A3 Development of a preventive vaccine for filovirus infection in primates
12/02/2004	WO2003025119A3 Compositions comprising immunostimulatory oligonucleotides and uses thereof to enhance fc receptor-mediated immunotherapies
12/02/2004	WO2002051981A3 Defects in periaxin associated with myelinopathies
12/02/2004	US20040244070 Expression of polypeptides in rod outer segment membranes
12/02/2004	US20040244062 Use of protein inhibitors as antithrombotic agents
12/02/2004	US20040243097 Antiproliferative drug and delivery device
12/02/2004	US20040242529 Vector encoding inactivated telomerase for treating cancer
12/02/2004	US20040242528 Intravenous delivery of polynucleotides to cells in mammalian limb

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